Calico Life Sciences Job Trends

We are seeking a scientist to join our Peptide Chemistry team. In this role, you will drive peptide drug discovery projects that sit at the nexus of empirical medicinal chemistry and Calico’s proprietary Machine Learning (ML) peptide design platform. You will collaborate cross-functionally with ML scientists, medicinal chemists, automation specialists, and biologists to explore structure-activity relationships (SAR). By leveraging a rapid design-make-test cycle, you will accelerate the optimization of therapeutic peptides and contribute to the evolution of a world-class synthetic engine. Key Responsibilities Drive Discovery Lead peptide drug discovery campaigns from initial hit identification through to IND-enabling studies Innovate Synthetic...

Calico is seeking a Principal Scientist, Drug Metabolism and Pharmacokinetics to join our Drug Discovery team. This position is a unique opportunity to shape the DMPK strategy and contribute to the development of innovative therapeutics. This role will function as an individual contributor, collaborating closely with external partners such as Pharma and CROs. Position Responsibilities Strategic Leadership Develop and implement the DMPK strategy to support drug discovery and development programs Provide expert DMPK guidance and input to project teams Represent the DMPK function in cross-functional meetings and interactions with external stakeholders Stay abreast of the latest advancements in DMPK science...