Calico Life Sciences Job Trends

Calico is seeking an exceptional and experienced individual to lead our contracts and alliances group which provides business, contractual and intellectual property support for Calico’s external collaborations and internal research activities. This role will be responsible for working closely with Calico scientists and external academic and industry collaborators, to lead and negotiate a wide variety of agreements in support of Calico’s research and development programs, with assistance as needed from Calico’s legal and IP counsel. Agreements include, but are not limited to, sponsored research agreements, licenses, CDAs, material transfer agreements, master services agreements, consulting agreements, software agreements and related amendments....

Calico is seeking an experienced and strategic Director of Chemical Development to lead and oversee all aspects of process chemistry and manufacturing for our mid- to late-stage small molecule programs. This role is critical to advancing our pipeline toward commercialization and requires deep technical expertise, leadership, and cross-functional collaboration. Key Responsibilities Lead chemical development strategyfor small molecule programs from Phase 2 through commercialization, ensuring robust, scalable, and cost-effective processes Providetechnical leadershipin route selection, process optimization, impurity control, and analytical support in collaboration with internal teams and external partners ManageCMC timelines, budgets, and deliverablesin alignment with program goals and regulatory requirements...

Calico is seeking an experienced, highly motivated Director of CMC Biologics to lead and oversee all aspects of Chemistry, Manufacturing, and Controls (CMC) development for our biologic drug candidates. This strategic role will focus on guiding programs from Investigational New Drug (IND) submission through commercialization, with a strong emphasis on process optimization and subcutaneous formulation development. The ideal candidate possesses deep expertise in biologics CMC, a comprehensive understanding of the drug development lifecycle, and a proven track record of successfully advancing biologic products in a highly regulated environment. Key Responsibilities CMC Strategy & Leadership Develop and execute comprehensive CMC strategies...

Calico is seeking a highly skilled Director of Formulation Development to lead formulation and drug product development efforts for our mid- to late-stage small molecule programs, including oral solid dosage forms and parenteral formulations. This role will be instrumental in progressing our pipeline from clinical development through commercial readiness, applying state-of-the-art formulation science and Quality by Design (QbD) principles. Key Responsibilities Leadprocess validationand supportingcommercial launchactivities Lead the development, optimization, and scale-up oforal solid dosage forms, including capsule, tablets, and mini-tablet presentations for small molecule drug candidates in mid- to late-stage development Lead the development, optimization, and scale-up ofparental therapies, including...

We are seeking a highly experienced and visionary Senior Director, Head of Toxicology to lead our toxicology and preclinical safety efforts. The ideal candidate will be a strategic and hands-on leader responsible for designing, implementing, and overseeing all toxicology studies, from early discovery through clinical development and registration. This role will be critical in ensuring the safety of our drug candidates and contributing to successful regulatory filings. Key Responsibilities Toxicology Strategy and Planning Develop and execute the overall toxicology strategy for each project and therapeutic candidate in the company's portfolio, aligning with project goals and regulatory requirements, from drug...