Calico Life Sciences Job Trends

The Cellular Models and Assay Technologies (CMAT) group at Calico is seeking a talented and creative bench Scientist to lead the design, optimization, and implementation of complex biochemical assays to support our drug discovery efforts. As an expert individual contributor, the successful candidate will perform advanced hands-on laboratory work while also managing external Contract Research Organizations (CROs) to scale our capabilities. The position requires the candidate to have extensive experience in enzymology, in vitro pharmacology, and the biophysical characterization of protein-ligand interactions. In this role, you will act as a thought leader, driving innovative assay technologies to advance therapeutic pipelines...

Calico is seeking an experienced and highly motivated Director/Senior Director, Compound Management to lead our Compound Management group. This individual will be a key leader in establishing, optimizing, and maintaining a robust compound and sample management platform, critical for accelerating our drug discovery efforts. The successful candidate will lead a team focused on the management of diverse small molecules and biologics, ensuring seamless support for internal and external research activities. Responsibilities Strategically govern all facets of compound and sample management, designing and building a comprehensive inventory system to serve as the critical interface for logistics and communications among R&D project...

Calico is seeking an accomplished Director of Analytical Chemistry to lead our small-molecule analytical development function. This leader will play a pivotal role in advancing Calico’s development portfolio, supporting programs from pre-IND through commercialization. The ideal candidate will have deep expertise in designing phase-appropriate analytical methods, shaping analytical regulatory strategies, and driving comprehensive lifecycle management. Key Responsibilities Expertise with developing analytical techniques and specifications for immediate release oral solid dosage, extended-release oral solid dosage, parenteral, and subcutaneous delivered products Oversee characterization and control strategies for drug substances and drug products in alignment with ICH guidelines and global regulatory expectations...