Calico Life Sciences Job Trends

The Systems Administrator is a member of Calico’s Information Technology team and manages physical and virtual servers, data storage, compute clusters, and cloud infrastructure used by Calico scientists. This position works closely with scientists who are leaders in their fields, advising and assisting them with their data science and high-performance computing needs. We are seeking a resourceful individual with expertise in a variety of system administration functional areas who enjoy delivering high performance computing and data solutions to a dynamic, creative research and development organization. Responsibilities Provision, monitor, and support Calico’s on-premises and cloud-based high performance computing clusters, storage, virtual...

Position description Calico is seeking an intern to join the Translational Data Sciences team.The Translational Data Sciences team bridges the gap between basic science and clinical application to further Calico’s mission of extending healthy lifespan. It accelerates Calico's translational research and empowers data-driven decision-making by transforming complex data into actionable insights grounded in biology. The successful candidate will be an enthusiastic team player, detail-oriented, extremely organized and comfortable working on complex problems across a wide range of biological contexts. In this position you will extend Calico’s internal AI infrastructure to interface with internal and external sources of single cell sequencing...

Position description Calico is seeking an intern to join the Parkinson’s Disease Initiative.To succeed, you will need to be an enthusiastic team player, detail-oriented, extremely organized and comfortable working on complex problems. In this position you will develop a novel imaging-based experimental system to study 𝝰-synuclein dynamics in vitro and in living cells, focusing on its oligomerization and aggregation regulated by disease-relevant perturbation. The successful candidate will work closely with members of the Parkinson’s Disease Initiative and the imaging team to develop a labeling strategy for 𝝰-synuclein using codon expansion technology. Responsibilities Optimize a genetic code expansion approach to site-specifically...

Position description Calico is seeking an intern to join the Automation Core team. To succeed, you will need to be an enthusiastic team player, detail-oriented, extremely organized and comfortable working on complex problems. In this position you will apply software engineering principles to real-world physical systems. You will move beyond simple scripting to help build the robust software tools that power our research, bridging the gap between code and robotic instruments. The successful candidate will work closely with members of the Automation Core and software engineering teams on developing Python APIs, improving test coverage, and prototyping tools that help our...

Position description Calico is seeking an intern to join the Gillich lab.To succeed, you will need to be an enthusiastic team player, detail-oriented, extremely organized and comfortable working on complex problems.In this position you will use CRISPR screening and cutting-edge functional genomics approaches to discover lung aging targets. The successful candidate will work closely with members of the Gillich and Cellular Phenotyping labs to establish a platform for co-culturing alveolar organoids derived from primary alveolar type 2 (AT2) cells with alveolar fibroblasts. Using this system, you will screen for reversal of lung aging phenotypes in the co-cultures using phenotypic and...

Position description Calico is seeking an intern to join the Kelley Lab.To succeed, you will need to be an enthusiastic team player, detail-oriented, extremely organized and comfortable working on complex problems.In this position you will advance on machine learning approaches for regulatory genomics, particularly developing and evaluating methods for analyzing regulatory sequence functions. The successful candidate will work closely with members of the Kelley lab, driving a project that we’ll shape together to derive greater biological insight from deep learning models of gene regulation. Responsibilities Develop and evaluate machine learning models for regulatory genomics, focusing on model interpretability Collaborate with...

Position description Calico is seeking an intern to join the Machine Learning (Molecule Design) group.To succeed, you will need to be an enthusiastic team player, detail-oriented, extremely organized and comfortable working on complex problems. In this position you will perform research to advance the state-of-the-art in modelling binding affinity. The successful candidate will work closely with members of the Machine Learning (Molecule Design) group on developing ranking models for molecular design applications and integrating them into a molecule design framework to generate designs. Responsibilities Gain expertise in state-of-the-art research in machine learning based molecule design Implement novel ideas for ranking...

Position description Calico is seeking an intern to join the Hahn group in their mission to investigate the mechanisms driving brain aging and age-related neuroinflammation. To succeed, you will need to be an enthusiastic team player, detail-oriented, extremely organized and comfortable working on complex problems. In this position you will support our efforts to harness novel screening systems (like this ) to study brain immune cells at scale, in order to identify novel regulators of their cellular physiology. The successful candidate will work closely with members of the Hahn group on combining novel and innovative primary and progenitor-derived cell culture...

Position description Calico is seeking an intern to join the Protein Science group.We are looking for a highly motivated, detailed-oriented, organized team player who is comfortable working on complex problems. The intern will work on the structural and functional characterization of proteins. The successful candidate will work with other members of the Protein Science team and collaborate with other groups at Calico to provide mechanistic insight into proteins of interest. The internship will provide the intern with valuable experience in scientific discovery in an industry setting. Responsibilities Express and purify recombinant proteins Play an active role in structural determination and...

Position description Calico is seeking an intern to join the Nile Lab to help characterize the function of novel E3-ligases expressed in tissue-specific and cancer-relevant settings. An intern in the oncology department will get hands-on experience in drug development and will have the opportunity to use and/or develop experience in designing and carrying out biochemical and cellular assays (including but not limited to protein purification, biophysical and enzymatic assays, and mammalian cell culture experiments). We are looking for a motivated scientist who is an enthusiastic team player, highly organized, detail-oriented, and comfortable tackling complex problems at the bench. The successful...