Calico Life Sciences Job Trends

Calico seeks a Senior Machine Learning Research Engineer to join the team building the computational engine that closes the design-test-learn cycle in molecular design and scales the ML infrastructure across the company. Working closely with a biology-fluent group of researchers and engineers, you will build ML platforms to accelerate their research, translate advanced ML methods into scalable code, and iteratively refine these tools as they apply them to real-world drug discovery problems. If you are passionate about building high-impact ML systems, thrive in ambiguity, and are excited to move fluidly between optimizing data pipelines and deploying generative models, this is...

Calico is seeking a machine learning scientist to join a research group investigating how genome sequence determines regulatory function and how dysregulation of these programs drives aging. We develop sequence-based deep learning models that predict gene expression, chromatin accessibility, and other functional readouts directly from DNA. We use these models to interpret human genetic variation, map causal regulatory mechanisms, and identify promising intervention points. This work builds on a sustained research program at the intersection of deep learning and regulatory genomics, including Avsec, Ž. et al. Effective gene expression prediction from sequence by integrating long-range interactions. Nat Methods 18 ,...

We are seeking an experienced Associate Director, External Communications to join our Corporate Communications team. In this key role, you will develop and execute communication plans that increase awareness of Calico’s scientific advancements, clinical milestones, and partnerships. Reporting to the Senior Director of Corporate Communications, you will play a key role in maintaining a cohesive brand narrative that reinforces Calico’s overarching mission and translating scientific excellence into compelling external presence as we advance our lead programs toward potential commercialization and patient impact. In addition to subject matter expertise, this position will require strong collaboration and project management skills as you...

Calico is seeking an accomplished and motivated individual to step into the role of Nonclinical Safety Leader within our Toxicology and Pathology team. This leader will collaborate with innovative and diverse scientists and play a pivotal role in advancing Calico’s preclinical pipeline and development portfolio. The ideal candidate will leverage deep and proven expertise in toxicology to provide leadership for discovery and development projects, with flexibility to specialize or work across stages of development, therapy areas, and modalities. Responsibilities Act as a Nonclinical Safety representative and Subject matter expert representing toxicology on project teams to support on early- and late-stage...