Generate Biomedicines Job Trends

We are seeking to expand our Technical Development Team within Technical Operations by recruiting a highly experienced and collaborative Associate Director, Analytical Strategy and External Testing Oversight who will be responsible for providing external testing oversight and supporting QC operations for all biologics products in early- to late-stage clinical development up to product commercialization . Reporting to the VP of Technical Operations and working closely with CMC Analytical Development and other members of the Technical Development team, the successful candidate will be accountable for end-to-end technical QC oversight across multiple external global CDMO/CTL partners. This position includes establishing...

GenerateBiomedicines is seeking a detail-oriented and highly collaborative Clinical Trial Associate to support Phase 3 clinical trials within our Clinical Development team. Reporting to the Sr. Director of Late Stage Clinical Operations, this role will play a critical part in enabling high-quality execution of pivotal trials designed to support regulatory submissions and eventual product approval. The CTA will work cross-functionally with Clinical Supply, Data Management, Regulatory, QA, and CROs to maintain inspection-readiness, ensure compliance with GCP standards, and support key trial deliverables. This is an exciting opportunity for someone who thrives in high-accountability environments and is eager to contribute to...

Generate Biomedicines is seeking a visionary and dynamic Director to lead our Protein Analytics and Biophysics function within the Therapeutic Assay Sciences Department, a critical pillar of our AI-driven drug discovery engine. This role offers a unique opportunity to shape the future of biotherapeutic innovation by guiding a multidisciplinary team at the forefront of analytical and biophysical characterization of therapeutic proteins and their molecular targets. The ideal candidate brings deep expertise in protein analytics and protein-protein interactions, coupled with exceptional leadership and a passion for advancing the frontiers of biologics development. As a strategic leader, you will chart the direction...

About Generate Biomedicines Generate Biomedicines is a new kind of therapeutics company – existing at the intersection of machine learning, biological engineering, and medicine – pioneering Generative Biology™ to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. Generate has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development. We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically...

We are seeking a highly experienced and strategic Senior Counsel, Clinical Contracting – Legal & Regulatory to lead clinical contracting efforts across a portfolio of late-phase (Phase II-III) clinical trials. This role will be responsible for driving the negotiation and execution of a wide range of clinical trial agreements, and for advising internal stakeholders on contracting strategy, risk mitigation, and regulatory considerations. While the vast majority of this role (~80–90%) will be focused on transactional clinical contracts, the ideal candidate will also contribute in a strategic legal advisory capacity (~10%), supporting the General Counsel, Clinical Operations, and Tech Ops teams...

The Protein Engineering team is seeking a highly innovative and collaborative Senior Scientist I to drive the development and implementation of large-scale, NGS-based functional assays. In this role, you will lead the translation of Generate’s cutting-edge technologies into high-impact therapeutic applications that harness the full power of our computational and experimental platforms. This role will collaborate closely with teams across DNA Read/Write, Prototyping Lab, Machine Learning, and Early-Stage Biology to pioneer novel workflows for scalable functional screening. This is an ideal opportunity for a scientist who thrives at the interface of technology development and translational potential – someone who enjoys...

We are seeking a proactive and detail-oriented Counsel, Clinical Contracting to manage a high volume of global clinical site agreements and related legal documents in support of late-phase (Phase II-III) studies. Reporting to the Senior Counsel, Clinical Contracting, this individual will play a key executional role within the Legal and Contracts team and will collaborate cross-functionally with stakeholders in Clinical Operations, Finance, Regulatory, Legal, Clinical Development, and external CRO partners. This role is ideal for someone who thrives in a fast-paced, highly collaborative environment and is comfortable balancing process efficiency with strong contract execution and stakeholder engagement. This is a...

As GenerateBiomedicines transitions into late-stage development and prepares for global regulatory interactions, we are seeking an Executive Director of Clinical Pharmacology to lead strategy and execution for global Ph2/3 studies. Reporting to the Head of Clinical Pharmacology and working closely with the Head of Clinical Development, this role will drive the clinical pharmacology vision across our pipeline, with a strong focus on respiratory indications and global regulatory alignment. Here's how you will contribute Act as the subject matter expert for regulatory agency interactions on clinical pharmacology topics, including INDs, BLAs, and pediatric plans. Design and oversee modeling and simulation efforts...

We are seeking a visionary, execution-driven leader to head Generate’s CryoEM group—a multidisciplinary team operating one of the most advanced high-throughput structural biology platforms in the world. This role reports directly to the CTO and sits at the heart of our mission to transform biology into a programmable discipline. Our CryoEM facility wasn’t built to follow the field. It was built to change the rules, turning cryo-electron microscopy from a scientific bottleneck into a scalable engine for structure generation and foundational insight. At unprecedented speed and scale, this platform is essential to powering Generate’s ML platform and accelerating drug generation...

The Associate Director of TMF is responsible for the strategic leadership, operational oversight, and quality governance of the Trial Master File (TMF) process across clinical development programs. This individual ensures that TMF systems, processes, and documentation comply with applicable regulations (ICH-GCP, 21 CFR Part 11), company SOPs, and industry best practices (e.g., DIA TMF Reference Model). They will serve as the subject matter expert (SME) for all TMF-related activities, guiding internal teams and CROs to maintain inspection-ready TMFs at all times. The Associate Director of Clinical Records Management and SOP Development is an agile and proactive individual who will be...