Generate Biomedicines Job Trends

Generate is seeking an accomplished Principal Scientist to lead Target Binding efforts within our Protein Analytics & Biophysics (PAB) department. This individual will provide scientific and strategic leadership for protein–protein interaction, target-binding, and cell-binding measurements across multiple biotherapeutic discovery and development programs. The role will combine hands-on technical expertise, novel technology development, cross-functional program leadership, and direct management of junior scientists and research associates. The successful candidate will be an established industry expert in quantitative biophysical assay development, particularly for challenging systems such as integral membrane proteins, lipid- associated targets, detergent-solubilized proteins, and multispecific molecules. Here's how you will contribute...

Generate’s Prototyping Lab builds the experimental systems that let us measure protein function at unprecedented scale. By combining synthetic biology, large DNA libraries, high-throughput assays, and machine learning, the team creates workflows that turn complex biological questions into rich, usable datasets. We’re looking for two Scientists with a strong record in experimental synthetic biology to develop pooled screens capable of testing hundreds of thousands of protein variants in parallel to identify protein binders and modulators. You’ll shape these experiments via DNA library design, pooled in vitro protein display, and NGS-based enrichment analysis. For one of the two roles, we...

The Associate Director will lead a talented scientific team working at the intersection of biological engineering, protein science, automation, and data-enabled discovery. You will help define how difficult and diverse protein targets are designed, produced, characterized, and delivered to project teams with greater speed, scale, quality, and scientific insight, working at the intersection of biological engineering, protein science, automation, and data-enabled discovery. Your leadership will directly influence critical program decisions, the success of novel protein modalities in discovery, the technologies and capabilities we build, and the inclusive, high-performance culture we create. At GenerateBiomedicines, this is an opportunity to combine deep...