Vertex Job Trends

General/ The Senior Director, CGT Quality Systems, Personalized Medicine provides strategic Quality leadership for personalized medicine and advanced cell therapies across the patient journey. The role is accountable for advancing Quality oversight, governance, compliance, and continuous improvement while ensuring efficient, patient-centric process across the end to end patient journey. This highly cross-functional position requires strong matrix leadership and partnership with Global Quality and Manufacturing, MS&T, Regulatory, Commercial, and Supply Chain stakeholders. Success requires the ability to influence enterprise decisions, build strong partnerships, and drive alignment through executive presence and effective communication. The ability to balance long-term vision with flawless execution...

Committed to advancing breakthrough treatments for patients with immune-mediated diseases, Vertex is building the clinical organization to match its scientific ambition in immunology. We are seeking a physician-scientist with a comprehensive understanding of molecular pathways as drivers of inflammatory and autoimmune diseases across a range of organs — and of the investigative treatment landscape targeting those pathways — to help shape Vertex's immunology portfolio beyond existing programs. Povetacicept, our lead immunology asset, is a differentiated TACI-Fc fusion protein that dually inhibits BAFF and APRIL, now advancing into a broad portfolio of antibody-mediated autoimmune indications with compelling early signals. As Executive...

Vertex is seeking a Senior Director, Solution Architect – Core Technology to serve as a senior individual contributor responsible for defining and driving an integrated architecture strategy across infrastructure and collaboration platforms in a global, GxP-regulated biopharma environment. This leader will establish the foundational architecture function within Core Technology and partner closely with domain leaders across cloud, network, collaboration, end-user computing, workplace technology, and service management. This role will ensure that enterprise technologies are cohesive, scalable, secure, and compliant, while helping shape a unified AI and digital workplace strategy across Microsoft 365, cloud platforms, and end-user environments. This role will...

The Portfolio & Program Management Business Technology Director is a role within the Portfolio & Program Management (PPM) organization and newly formed Center of Excellence. The incumbent is responsible for business ownership of technology platforms and AI tools supporting PPM and the broader Transactions, Alliances, and Portfolio Management (TAPM) organization, with accountability for enabling integrated planning, portfolio reporting and analytics, and scalable new ways of working. This role leads cross-functional efforts to evolve project management systems, strengthen data governance, and advance an integrated, AI-ready portfolio technology environment. Key Duties and Responsibilities Partner with TAPM leadership to shape and execute the...

The Kidney Territory Account Manager (KTAM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs), developing a strategic business plan, communicating thorough disease and product knowledge to HCPs and centers of care. This role must understand market dynamics in rare, complex disease states, demonstrate excellent judgment, and be motivated by the desire to improve patients' lives. The KTAM will report into a Regional Field Leader (RFL) and is responsible for leading engagement with nephrologists and serving as an account manager for specialty kidney clinics. Key Duties and Responsibilities Establishes meaningful and professional relationships with nephrologists and related...

The Clinical Study Quality Lead (SQL), Associate Director is responsible for advanced quality assurance oversight of clinical trial operations and applicable vendors, across a range of study phases within assigned disease area(s). The SQL will ensure clinical trials are conducted in accordance with GCP requirements, applicable protocols, Vertex policies and procedures and quality standards as set forth in the Quality Management System. Overall, the SQL is responsible for the development and execution of audit/quality plans, accurately identifying and communicating compliance risks and overseeing action plans to mitigate risks, real-time study inspection readiness oversight, and collaboratively identifying and driving inspection preparedness...

The State Government Affairs Director is responsible for supporting the company’s state government affairs strategy across several functional areas, including marketing, communications, policy, and medical affairs within their designated region. This role will help lead the company’s ongoing efforts to build and sustain meaningful relationships and collaborations to support the needs of patients and advance our company’s goals. This role will be responsible for grassroots campaigns execution across disease areas. Field-based position. Incumbent resides in the region (TX, TN, AR, LA, OK) Key Duties and Responsibilities Develops, coordinates, and leads the company’s state/regional public policy efforts. Collaboratively creates and leads...

The Senior GCP Operational Quality Manager conducts quality assurance oversight and management activities of clinical trial operations to ensure Vertex trials are conducted in accordance with Good Clinical Practice (GCP) guidelines, applicable regulations, protocols and Vertex policies and procedures. These activities include the development and execution of study level audit plans, accurately identifying and communicating compliance risks and overseeing action plans to mitigate risks, monitoring quality issues and compliance metrics, investigation and CAPA management, and proactive inspection readiness activities. Key Duties and Responsibilities Serves as the Quality Lead for assigned clinical programs providing GCP compliance interpretation, consultation, and other support...

Vertex is seeking an experienced scientist eager to help develop cutting-edge small molecules and the science underpinning the analytical control of their syntheses. As a member of the Drug Substance Control Strategy team in Analytical Development, this role will support synthetic drug development programs at Vertex with a focus on small molecule drug substance process and control strategy development across clinical and commercial-enabling phases. Specifically, the individual will oversee and execute experiments to develop the overall control strategy for novel drug substances, collaborate closely with associated CMC functions, and act as a subject matter expert liaison with our global network...

Job Summary The Principal Engineer, VaiDA Mobile Experience will help bring Vertex’s AI experience tool, VaiDA, to life through intuitive, high-quality mobile experiences that make AI accessible wherever work happens. This role will design and develop secure, performant, and user-friendly mobile capabilities that connect seamlessly to Vertex’s AI and agentic platform, while also supporting existing mobile applications across Vertex. The ideal candidate combines strong mobile engineering expertise with a sharp eye for usability, polish, and responsiveness, and can translate complex AI-driven functionality into clear, elegant mobile interactions. This person will play a key role in making VaiDA a trusted and...

The Senior Medical Director, Patient Safety, Disease Area Safety Head (DASH) will lead all safety and benefit-risk related activities for products within the role's Disease-area and/or Franchise, including pre-franchise products from first in-human clinical trials, into and throughout commercialization. This role will assist Global Patient Safety (GPS) Leadership in ensuring the consistency and compliance in the safety assessment, analysis and reporting for all designated product(s) throughout Vertex’s world markets. Directly and/or via oversight of direct reports, the role will lead pre-marketing risk assessment, planning for First-In-Human (FIH) studies, safety content of key Modules (SCS, CLO, Labelling) in regulatory authority submissions...

The Clinical Development Associate Medical Director will serve as the Medical Lead for clinical trials, working with cross-functional teams on trial strategy, design, execution, and reporting. In addition to oversight and accountability for the study as a whole, this role will serve as the internal primary Medical Monitor accountable for monitoring the safety of enrolled subjects and ensuring scientific integrity. The incumbent may participate in other projects to support the clinical development program. Key Duties and Responsibilities Participates in the development of Study Protocols, Investigator's Brochures, Clinical Development Plans and other key documents in conjunction with other line functions and...

The Manufacturing Process & Technical Quality Associate Director provides end-to-end l quality oversight for cell and gene therapy programs across clinical development, commercialization, product launch, and post-approval lifecycle management. The role is responsible for establishing product quality standards for both established and emerging technologies, ensuring alignment with regulatory expectations and industry best practices, and proactively identifying and mitigating product quality risks throughout the product lifecycle and end to end patient journey. This position partners closely with Manufacturing, Technical Operations, Regulatory Affairs, and Quality stakeholders to support program execution and governance, ensuring business, regulatory, quality, and operational objectives are achieved while...

This notice is being provided as a result of the filing of an application for permanent alien labor certification for the below job opportunity. Any person may provide documentary evidence bearing on the application to the Certifying Officer, U.S. Department of Labor, Employment and Training Administration, Office of Foreign Labor Certification, 200 Constitution Avenue NW, Room N–5311, Washington, DC 20210. Phone (202) 693-2991. Employer Vertex Pharmaceuticals Incorporated Chemistry Manufacturing Controls Manager Job Location 50 Northern Ave., Boston, Massachusetts 02210 Openings 1 Job Type Full Time Duties Review chemistry manufacturing control (CMC) sections of regulatory submissions, as well as...

The People Analytics Sr. Manager will play a pivotal role in shaping Vertex’s HR data strategy by leveraging advanced analytics, experimentation, and storytelling to drive data-informed decisions across the employee lifecycle. This role will partner closely with HR and business leaders to uncover insights, design experiments, and communicate findings that influence talent strategies and organizational effectiveness. The People Analytics Sr. Manager will be focused on building scalable data and AI solutions and translating research and analytics into actionable business insights Key Duties and Responsibilities · Lead the design and execution of people analytics projects that support strategic HR initiatives, including...

Vertex is seeking a talented, experienced analytical chemist for late-stage product development in a commercial setting with an interest in Process Excellence. Working directly with our contract manufacturing organizations and a highly diverse group of scientists at Vertex you will solve complex problems encountered in commercial production/manufacturing of drug products. You will be part of an organization that thrives on innovation and is at the forefront of implementing Quality by Design and Continuous Manufacturing. To be considered for this position the applicant will need to be a collaborative, experienced and competent analytical chemist with a history of developing, implementing and...

The Senior Director, Business Operations Lead is a senior role within the Business Operations function supporting Commercial Manufacturing and Technical Operations (CMTO). Reporting to the Executive Director, Business Operations and Performance , this role is accountable for product-level business leadership across commercial manufacturing activities, with a primary focus on CDMO business management, manufacturing performance governance, readiness and growth planning, cost of goods oversight, and scenario-based business decision support. This individual represents the business position for assigned product(s) across governance forums and key cross-functional decision-making bodies. The role ensures that product business requirements are translated into manufacturing priorities, performance expectations, contractual...

The Senior Medical Science Liaison (Sr MSL) will play a crucial role in supporting the pain program, with a specific focus on near-term launch. The Sr MSL serves as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with (Allied) Health Care Providers/Professionals (HCPs) and other key stakeholders involved in healthcare decision making to ensure the appropriate dissemination of clinical, scientific, and health economic data with respect to pain and Vertex’s compounds in a timely, ethical, and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights...

Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. The Associate Director role is within HEOR’s Analytics Center of Excellence (CoE), a specialized team that provides strategic and technical support to HEOR, Market Access & Pricing, and the broader commercial organization. In this role, the Associate Director will primarily support HEOR disease/asset teams in real-world observational and claims data research activities. The Associate Director will support colleagues looking to answer key questions that can be addressed...

Role Summary We are seeking a n innovative high performing individual to support global commercial Field (Veeva CRM) platform delivery. This role will integrate AI-driven solutions into CRM processes, enabling scalability, operational efficiency, and enhanced demand management. The ideal candidate will bring strong organizational, communication, and analytical skills, with a focus on leveraging AI tools and methodologies to optimize platforms, streamline governance, and improve team operations in a regulated, global environment. Additionally, the role will emphasize ensuring operational efficiency with Managed Service Providers (MSPs) and adherence to DevOps standards and best practices. Key Responsibilities Business Analysis Gather, analyze, and document...

The Senior Administrative Assistant provides experienced office/business support to a department. The Senior Administrative Assistant generally reports directly to a(n) Country Manager, Executive Director or Vice President-level manager. Key Duties and Responsibilities Manages calendars for assigned personnel, including meeting scheduling (both internal and off-site meetings), accepting/declining invites, meeting prioritization, securing conference rooms, ordering catering and "day-of" logistical and administrative support Serves as a departmental resource for Vertex's internal technologies (i.e; Procurement, SharePoint, Concur, Vertex U, VLearn, etc.) Exchanges and integrates information from stakeholders into departmental reports Books flights/hotels, completes expense reports, and arranges team lunches/dinners and offsite meetings for assigned...

We are seeking a dedicated and skilled Senior Research Associate to join our Tissue Dissection Group within our Molecular & Cell Biology group. The successful candidate will play a critical role in generating high-quality cells and tissue samples from primary human organs, contributing to various Vertex research programs. This position requires expertise in human tissue dissection, a commitment to excellence, and a deep respect for the gift of donated human tissues. Key Duties and Responsibilities Perform dissection of human tissues, including dorsal root ganglia (DRG), lungs, kidneys and precision-cut tissue slices. Develop and optimize dissection workflows and methods to enhance...

Vertex is seeking an Agent Engineer, Agentic AI Platform to help create the next generation of AI agents that deliver practical value across internal and user-facing experiences. This role will focus on prototyping, building, and productionizing multi-step agent workflows that are deeply integrated with enterprise systems, business processes, and digital products. The ideal candidate is energized by fast-moving AI technology but grounded in strong engineering discipline. This individual will use a forward deployed engineering mindset to work closely with stakeholders, rapidly iterate on real-world use cases, connect agents to APIs and business systems, and continuously improve quality through measurement and...

Vertex is seeking an Integrations Engineer, Agentic AI Platform to connect the AI/agentic platform to the systems, tools, and data sources that make AI valuable in real enterprise workflows. This role will focus on designing and implementing secure, scalable, and reliable integrations across internal platforms, third-party applications, and business-critical services. The ideal candidate brings strong expertise in MCP/A2A protocols, APIs, event-driven architectures, authentication patterns, and enterprise integration design. This individual will play a key role in ensuring AI capabilities are embedded into day-to-day work at Vertex and not as isolated proofs of concept, but as production-ready solutions integrated into the...

The Lab Automation Engineer will be a part of a team dedicated to designing, implementing, and validating automation solutions, across various automation platforms (Hamilton/Biomek/etc.), with a moderate degree of supervision. This role will support multiple disease areas and advance automation capabilities within Vertex Cell & Genetic Therapies. This role will develop an understanding of the research and development processes in order to establish new capabilities and improve efficiencies through automation enhancements. This is an onsite position at our Leiden Center research site in Boston. Key Duties and Responsibilities Translates manual research and development processes into the design of automation systems....

General position summary The Senior Manager, RDQ Learning & Documentation Governance will lead the oversight and coordination of R&D Quality (RDQ) learning governance, documentation governance, and operational readiness activities in partnership across RDQ, with Global Quality Training, Global Documentation, and cross-functional stakeholders. This role will serve as a central coordinator and governance lead for RDQ learning, documentation, and curriculum management activities, ensuring alignment to evolving regulatory expectations, quality systems, inspection readiness priorities, and organizational transformation initiatives. The individual will drive consistency, oversight, and continuous improvement of the RDQ curricula, such as establishing role based training and partner with stakeholders to...

Vertex is seeking a Sr. Principal AI Engineer, Agentic AI Platform to design, build, and optimize the shared platform capabilities that power AI-enabled products and intelligent workflows across the enterprise. This role will focus on delivering production-grade platform services for model integration, prompt and workflow orchestration, evaluation, observability, performance optimization, and agent lifecycle management. A key focus of this role will be enabling a build/bring-your-own-agents capability within the Agentic AI Platform, allowing teams across Vertex to create, integrate, customize, and operationalize their own agents using shared platform standards, tooling, and governance controls. The ideal candidate combines strong software engineering fundamentals...

Principal Engineer, VaiDA User Experience Location Hybrid / On-site Vertex Pharmaceuticals is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. At Vertex, we combine cutting-edge science, technology, and human-centered thinking to solve complex challenges and improve lives. Our digital and AI initiatives help empower employees across the organization with scalable, intuitive tools that accelerate innovation and decision-making. Role Summary Vertex Pharmaceuticals is seeking a Principal User Experience Engineer to shape the future of VaiDA, our enterprise AI platform for employees across Vertex. This role will design and build polished, seamless...

The Business Engagement & Technology Principal Analyst will be a technical resource in ensuring delivery and support of commercial-off-the-shelf (COTS) and a wide range of custom solutions in support of their business partners. The Business Engagement & Technology Principal Analyst will partner with business leadership to deliver capabilities and execute on a roadmap that align to support business strategy . Additionally, the Business Engagement & Technology Principal Analyst will maintain reliable, scalable and compliant systems that easily meet business needs by efficient delivery and enhancements that provides opportunities for developing and implementing innovative solutions and integrations. Key Duties and Responsibilities...

Vertex is seeking a Sr. Principal AI Engineer, Agentic AI Platform & Control Tower Ops to define and build the foundational enterprise AI platform that powers intelligent applications across the enterprise. This role will lead the design and implementation of scalable, secure, and reusable capabilities for agentic AI, with a strong focus on retrieval-augmented generation (RAG), orchestration frameworks, evaluation systems, and platform architecture. In addition to building out the core platform, this leader will own the vision for a centralized AI Control Tower / Control Plane / Gateway that enables agent monitoring, observability, policy enforcement, governance, and operational controls across...

Why Join Us? Vertex is a transformative biotechnology company that creates new possibilities in medicine to transform diseases and improve people’s lives. The company currently has five drugs on the market that treat the underlying cause of cystic fibrosis, one therapy on the market that is a cell and gene therapy treatment for sickle-cell disease and transfusion-dependent t β-thalassemia, and one drug on the market for the treatment of acute pain. It has also developed a deep pipeline, investing billions of dollars into R&D over the past two decades. Vertex is seeking an experienced Legal and Compliance professional to join...

The Business Engagement & Technology Associate Director will be a key technical resource in ensuring the planning and delivery of key commercial-off-the-shelf (COTS) and a wide range of custom solutions in support of their business partners. The incumbent will partner with business leadership to develop capabilities and systems roadmaps that align to support business strategy. Additionally, the Business Engagement & Technology Associate Director will ensure team members maintain reliable, scalable and compliant systems that easily meet business needs by efficient delivery and enhancements that provides opportunities for developing and implementing innovative solutions and integrations. Key Duties and Responsibilities Become a...

Vertex is seeking an Agent Engineer, Agentic AI Platform to help create the next generation of AI agents that deliver practical value across internal and user-facing experiences. This role will focus on prototyping, building, and productionizing multi-step agent workflows that are deeply integrated with enterprise systems, business processes, and digital products. The ideal candidate is energized by fast-moving AI technology but grounded in strong engineering discipline. This individual will use a forward deployed engineering mindset to work closely with stakeholders, rapidly iterate on real-world use cases, connect agents to APIs and business systems, and continuously improve quality through measurement and...

Vertex is entering a transformative phase in its data journey—where trusted, governed master data is foundational to enabling enterprise-wide analytics, AI, and operational excellence. We are seeking an execution-focused Associate Director, Customer Master to lead the Customer(HCP/HCO) master data domain within Vertex’s Enterprise Master Data Management (MDM) organization reporting to the Director, Enterprise MDM. This role will be responsible for one of the most critical and complex data domains at Vertex. The Global Healthcare Entity Master (GHEM) supports a broad range of cross-functional processes and is foundational to commercial operations, analytics, and decision-making. This role will provide end-to-end ownership of...

Vertex is seeking a Principal Analyst, G&A Technology to support our Legal, OBIE , and Corporate Communications functions. In this role, you will partner closely with stakeholders to deliver technology solutions that strengthen operations, enhance the user experience, and support strategic priorities across corporate functions, with a particular focus on Legal, Compliance and Corporate Communication needs. The ideal candidate combines deep expertise in technology delivery, stakeholder engagement, and cross-functional leadership with a proven track record of partnering with Legal, Compliance, and Corporate Communications organizations in complex, highly regulated environments. This person will translate business needs into scalable technology solutions, lead...

Job Summary Vertex is seeking a Director, Field Effectiveness to understand, analyze, and build solutions to maximize field effectiveness and drive commercial performance. This leader will play a critical role in shaping and advancing field effectiveness strategies, with a focus on targeting effectiveness, incentive design, account planning, and field force performance optimization . The Director will serve as a key thought partner to the sales and business unit leadership, field team leaders, I&A partners, and other cross-functional stakeholders to ensure field teams are equipped with the insights, tools, and performance frameworks needed to execute with impact. This role requires a...

The Chemistry Manufacturing Controls (CMC) Associate Director leads and executes global regulatory CMC strategies across investigational and commercial products focusing on biologics. This role is accountable for authoring, reviewing, and delivering high-quality regulatory submissions, while serving as the primary CMC interface with Health Authorities. The role integrates advanced digital and AI-enabled approaches to enhance the quality, consistency, and efficiency of regulatory document preparation and review. Key Duties and Responsibilities Leads preparation, review, and lifecycle management of CMC sections of global regulatory submissions for biologics (INDs/CTAs, NDAs/BLAs/MAAs) Develops and drives global CMC regulatory strategies for assigned programs Serves as primary regulatory...

The Patient Safety Epidemiology Associate Director leads safety and regulatory epidemiology activities for Vertex products across multiple therapeutic areas and throughout all phases of lifecycle. This includes execution of post-marketing regulatory study research strategies, leading comprehensive epidemiologic feasibility assessments, development of epidemiologic study designs, overseeing study implementation, interpretation of findings and communication to internal and external audiences. Key Duties and Responsibilities Major contributor and driver to the company safety risk management, signal detection, benefit/risk assessments, and post-marketing regulatory research strategies Expected to research the epidemiology of specific disease areas and events of interest, lead evaluation of data sources and data...

Vertex Patient Support (VPS) is seeking an experienced and highly motivated Associate Director, Assurance (AD, Assurance) to serve as a key leader within the US Patient Support Center of Excellence (COE) Program Quality team. Reporting to the Director of Program Quality, the AD provides operational leadership for the execution of the assurance program across Cystic Fibrosis, Kidney, and Hematology Patient Support Programs (PSPs) supporting both GxP and non-GxP functions. The Associate Director will provide oversight for the execution of quality assurance activities, including internal audits and continuous monitoring, corrective and preventive action (CAPA) management, and quality reporting. In collaboration with...

Overview At Vertex, the People Advisor delivers high-impact, manager-facing HR advisory support that helps leaders make effective people decisions, strengthen organizational health, and create a consistently positive employee experience. This role supports the Corporate Functions portfolio and will partner closely with managers through everyday people decisions, moments of change, and critical workforce cycles. Operating within Vertex’s HR service-based model, the People Advisor focuses on proactive coaching, early intervention, talent planning, program enablement, and people insights while partnering with People Experience, Employee Relations, HR Business Partners, HR Operations, and Centers of Excellence to route transactional, programmatic, or formal investigative work to...

Vertex is entering an exciting phase of commercial diversification. As we expand into new pipeline disease areas and new geographies, we are investing in data, technology, and AI to scale commercial operations globally. The Commercial, Medical and External Affairs Technology team is expanding our capabilities with increased investment in data, platforms, and AI. This role establishes the end-to-end architecture required to scale AI and digital capabilities across the enterprise. The Senior Director, Commercialization Technology Architect is responsible for defining and governing target-state architectures, integration patterns, and platform standards that enable scalable, secure, and compliant AI solutions. This role ensures technologies...

The Senior Biostatistician II will perform scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with guidance and mentoring on new and complex issues. The incumbent will complete assigned work in a resourceful manner and create alternative approaches to achieve desired results. The incumbent will develop a good knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. Key Duties and Responsibilities Within assigned area, designs, develops and executes the technical/statistical infrastructure for the conduct and evaluation of clinical trials, observational studies, or real world data (RWD) investigations, including related areas/activities. Participates...

As the Strategic Sourcing Manufacturing & Supply Director for Small Molecules, you will be part of a fast-growing, innovative organization at the company’s world headquarters in Boston, MA. The department is committed to a trusting and collaborative culture where growth and development are valued. We engage proactively with stakeholders to understand their needs and deliver results for our company and for patients. If you are looking for an entrepreneurial, hands-on, team-oriented environment where you can make a meaningful impact, this is the right place for you. This is a key leadership role focused primarily on materials and services that support...

The Senior Director, Finance Integration Lead will serve as the finance business partner for M&A activities. This role is critical to enabling a disciplined, well-governed integration that supports business continuity, financial transparency, strong controls, and alignment with Vertex standards. This role will oversee the financial strategy, execution, and outcomes of M&A integrations, ensuring that cross-functional value capture assumptions, financial considerations, and integration-related commitments are clearly baselined, tracked, governed, and supported throughout the integration. The role will also ensure a seamless transfer of financial information, institutional knowledge, and ongoing accountabilities to Vertex functional finance teams as the integration progresses. The Senior...

The Health Systems Marketing Associate Director is responsible for the development and execution of key personal and non-personal promotion marketing tactics targeting Health Systems and hospitals. Specifically, this role will own the evolution of formulary decision maker messaging, core Health Systems promotional materials (value proposition and economic tools), and digital media strategy and execution. Vertex recently launched JOURNAVX, an oral, non-opioid medication for the treatment of moderate-to-severe acute pain. Promotional education is critical to the success of JOURNAVX. This role will develop high impact personal and digital promotional content and work closely with colleagues on the health systems marketing team,...

Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. The Senior Manager Director role is within HEOR’s Analytics Center of Excellence (CoE), a specialized team that provides strategic and technical support to HEOR, Market Access & Pricing, and the broader commercial organization. In this role, the Senior Manager will primarily support HEOR disease/asset teams in real-world observational and claims data research activities. The Senior Manager will support colleagues looking to answer key questions that can be...

The Director, Chemistry Manufacturing Controls (CMC) leads a Regulatory CMC team responsible for developing and executing global regulatory strategies across multiple investigational and commercial products in the small molecule portfolio. This role provides strategic leadership for complex regulatory CMC activities, oversees Health Authority engagement, and ensures regulatory requirements are effectively integrated into development and commercialization plans. The Director drives organizational excellence through talent development, process innovation, and the application of digital and AI-enabled capabilities to enhance the quality, consistency, and efficiency of regulatory decision-making, document preparation, and submission execution. Key Duties and Responsibilities Leads development and execution of global CMC...

The Associate Director, CMC Quality Compliance and Inspection Readiness, is responsible for inspection readiness and compliance of external sites including evaluating, improving, and monitoring commercial level quality compliance and quality culture. Key Duties and Responsibilities Responsible for inspection readiness and compliance programs for external operations. Works cross-functionally and cross-company to ensure sites achieve and maintain a state of inspection readiness. Drive identification and resolution of issues, gaps and risks through collaboration with operational areas, assessments, audits, and evaluation of trends. Support and oversee inspection execution including responses and closure of CAPAs. Collaboration and Integration Serve as an integrator across multiple...

The CMC Quality Compliance Director is responsible for inspection readiness and compliance of internal and external sites including evaluating, improving, and monitoring commercial level quality compliance and quality culture. This position provides technical and strategic leadership for inspection readiness and compliance including processes and associated governance across all GMP areas. This position focuses not just on the “what” but the “how”, ensuring phase appropriate and risk-based compliance. Key Duties and Responsibilities Accountable for inspection readiness, inspection management, and compliance programs across all GMP areas including external CMOs and internal manufacturing/testing sites. Monitor and interpret cGMP regulatory guidelines and trends in...

General / Vertex is entering a transformative phase in its AI journey, where responsible, trusted, and compliant AI is foundational to accelerating innovation, improving patient outcomes, and enabling enterprise-wide productivity. We are seeking a visionary and execution-focused Director, AI Governance & Policy to lead Vertex’s enterprise AI Governance program and establish the policies, operating models, and technology platforms that enable safe, ethical, and business-enabling adoption of AI across the company. This role will lead the governance of generative AI, agentic AI, machine learning, and AI-enabled business solutions. The Director will oversee AI policy development, risk management, governance operations, technology...