Vertex Job Trends

Vertex is seeking an Associate Director of Patient Support & Engagement Analytics to lead analytics initiatives that optimize patient services and programs, primarily supporting therapies for hemoglobinopathies such as sickle cell disease and beta thalassemia. This role will leverage data-driven insights, patient journey analytics, and predictive modeling to enhance patient engagement and improve operational efficiency across Vertex’s patient support ecosystem. The ideal candidate is a highly skilled individual contributor with a proven ability to translate complex concepts into clear, actionable insights for diverse stakeholders. They demonstrate exceptional attention to detail and accuracy in deliverables, while working independently and proactively engaging...

The Associate Director, Strategy and Operations, US Market Access is a key partner and advisor to the VP US Market Access and Market Access Leadership Team (MALT) on a variety of strategic, operational, and organizational matters. The role requires both strategic thinking as well as the ability to drive operational execution through preparing, implementing, and effectively managing tactical initiatives. The ideal candidate is a highly motivated and highly organized individual with exceptional emotional intelligence, communication skills and judgment with the ability to manage complex details, understand the business, and drive action. This role reports directly into the Vice President of...

The Learning Management Systems (LMS) Manager will oversee the administration and optimization of Vertex University’s LMS platform, Cornerstone OnDemand. This role ensures seamless delivery of learning programs by managing system configurations, resolving technical issues, and partnering in the implementation of new releases. The position plays a critical role in supporting Vertex’s learning strategy and enhancing user experience across the organization. Key Duties and Responsibilities Serve as the primary administrator for Cornerstone OnDemand, managing system configurations and ensuring data integrity Partner with stakeholders in development of custom and automated LMS reporting Advise on best practices for learning assignments and data collection...

The Quality Specialist will provide QA support for manufacturing operations, analytical laboratory operations, and materials management for the internal programs at Vertex Manufacturing Center (VMC), Boston, MA. The position will be a part of the QA operation floor support team. This role will review & support activities related to product disposition, including batch data, batch records, deviations, in-process data, EM data, QC release testing, and other quality systems documentation. The Quality Specialist supports or executes daily activities related to equipment or instrumentation supporting Facilities, Utilities, Manufacturing, and Labs. The position will support multiple production functions (from Quality operations to Quality...

The Cybersecurity Senior Engineer II provides day-to-day technical support for one or more security capabilities and services, including the implementation of new solutions and processes to increase efficiencies, and optimize and expand service offerings for both on premise and the cloud. Key Duties and Responsibilities Collaborates with members of the technical and business communities to integrate new applications into the Vertex ecosystem Analyzes and resolves software and hardware problems and ensures that the correct processes are followed in change management for tracking and reproducibility Helps deploy and maintains large-scale enterprise-level security services Supports projects from requirements gatherings and scope to...

Job Summary Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. The role is as a Director within the Modeling Center of Excellence (CoE), a designated group within the HEOR team that provides strategic and technical modeling support to HEOR, Market Access & Pricing, and the broader commercial organization. The main responsibility of the Director will be to lead the team that supports the HEOR disease/asset teams in developing health economic models, including models that will...

The Project Management & Strategic Operations Director - Clinical Development serves as the end-to-end program lead for large-scale strategic programs of high business value. Drives benefit achievement by leading program initiation, planning, solution design and build, and by measuring key performance indicators and solution adoption. Engages other colleagues/resources and assigns appropriate responsibilities to support achievement of program roadmap and project plan(s). Independently applies expert knowledge of advanced methodologies, selecting and applying high-level project management tools to conduct analyses, reporting and related activities for assigned projects. Contributes to the development of internal protocols and processes used to carry out program management...

General/ Vertex is in an exciting time of growth and innovation, and technology and data are valued as strategic assets. The Commercial Technology team in the Data, Technology and Engineering (DTE) organization is seeking an experienced technology leader to head the strategy, planning and delivery of key technology capabilities to support Vertex’s North America Kidney and CF business units and Patient Services function. The Business Unit team includes sales and marketing for each disease area, and the Patient Services team support North America patient services for all disease areas. Vertex is in a transformational period of growth; we are investing...

The Associate Director, Digital Marketing HCP will be responsible for developing and executing digital marketing strategies to enhance the engagement and communication with healthcare professionals (HCPs) within the US Kidney Business Unit. This role will focus on creating and implementing omnichannel communication journeys, non-personal promotion (NPP) execution, and leveraging search and AI strategies. The Associate Director will also serve as the Legal and Regulatory HCP Digital lead, ensuring alignment with regulatory and compliance standards. Key Duties and Responsibilities Develop and execute HCP digital marketing strategies, including content creation and omnichannel communication journeys, to reach and engage HCPs effectively Lead the...

The Marketing Associate Director is accountable for understanding the market landscape, defining and developing key business activities and tactics to support goals of the brand/portfolio, and measuring the success of those activities/tactics. Key Duties and Responsibilities Partners with brand/team-lead to help shape the brand strategy, segment the market, develop messaging and launch into new segments, including label expansions Directs the development and implementation of strategic and tactical plans for assigned product Collaborates with Vertex external communications review committee to approve materials for external use with customers Generates and consolidates key insights across HCPs and patient stakeholders through market research, ad...

The Associate Director, Media/Social Marketing - HCP will lead the development and execution of comprehensive media and social marketing strategies to enhance the digital presence and engagement of the US Kidney business unit. This role will focus on driving influencer strategies, managing digital opinion leaders (DOLs), and leading HCP media planning and execution. The ideal candidate will have a strong background in media planning, media buying, analytics measurement, as well as channel selection and optimization. Key Duties and Responsibilities Oversee media planning and media buying activities to ensure effective allocation of resources. Develop Marketing content for media platforms for HCPs....

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

General/ The Real World Analytics (RWA) Senior Manager leads the execution of statistical analysis plans for observational research conducted by the RWE researchers ). The Senior Manager also advises on fit-for-purpose database selection, guides patient population selection, performs QC as needed and manages workload in support of one or more therapeutic areas. The (RWA) Senior Manager is a hybrid role requiring two core skills sets statistical programming and project management. Key Duties & Responsibilities Executes on statistical analysis and programming plans. Ensure quality and timely deliverables for all assigned studies/projects. Advises on database selection, patient population selection and statistical analysis...

General/ The Director, Quality Oversight Lead within Global Clinical Quality (GCQ) is responsible for strategic and operational oversight of key activities such as inspection readiness, the GCQ operational framework, continuous improvement initiatives, and expert guidance on computer systems assurance in a clinical trial setting. Additionally, the Director will be responsible for providing quality oversight to Clinical Development and Biometrics functional areas. We seek an individual with strong leadership skills, expert drug development and GCP knowledge, and advanced understanding of the application of inspection readiness principles in a clinical trial setting. This position reports directly to the Senior Director of Global...

Vertex is seeking to hire an Associate Director, NA Cystic Fibrosis (CF) Analytics & Reporting to join the North America Forecasting, Analytics, and Insights team in the Commercial organization. This role will provide analytics support for strategic commercial initiatives by identifying and quantifying market drivers, barriers, and opportunities using advanced analytical methods. Additionally, this role will provide support for ongoing analytics, quantitative tracking, and reporting of national and sub-national commercial performance of the NA CF business. This individual will work cross-functionally and lead requirement gathering, development, execution, and insight generation for performance analytics, dashboards, and present insights to stakeholders. The...

Vertex is seeking a talented strategic & operations colleague to serve in a critical role joining our US Pain Business Unit to support the ongoing launch of Journavx in moderate to severe acute pain, the first new class of medicines in over two decades on our journey to fundamentally transform pain management. The Associate Director , US Pain Strategy & Operations will drive critical strategic planning and execution as continue to scale launch within the US Pain Business Unit. We are seeking a candidate that has a strong track record in strategic and project management roles to report directly into...

The Executive Medical Director, Global Medical Lead (GML), Pain is a critical leadership role in Global Medical, responsible for the global medical strategy and impl eme ntation and tracking of global activities for a designated disease area(s) . Key responsibilities include, but are not limited to, disease area specific Integrated Medical Plan development, including the publication plan, global launch strategy and execution, scientific leadership, external medical expert engagement, and strategic alignment with commercial and other cross-functional business partners. This leader will also be critical in leading post-approval evidence generation strategy in the disease area. This leader reports directly to the...

The Senior Manager, Third-Party Risk Management (TPRM) will serve as the Subject Matter Expert (SME) for the operational processes of the enterprise-wide TPRM program. Reporting to the Senior Director of Strategic Sourcing Enterprise Third-Party Risk Management, this role will focus on managing day-to-day TPRM operations, ensuring seamless stakeholder engagement, and providing excellent user support. The Senior Manager will act as a liaison between vendors and business owners, triaging questions, facilitating communication, and tracking issues to resolution. The role also includes supporting the use and maintenance of TPRM tools (e.g., ProcessUnity, Archer, RiskConnect, or similar platforms) and driving the resolution of...

Vertex Pharmaceuticals is seeking an experienced and driven Technology focused Chief of Staff to support our Chief Digital and Information Officer in leading Vertex’s digital transformation and IT strategy. This high-impact role functions as a trusted advisor and operational leader for the Office of the CDIO, ensuring that Digital, Data, and Technology initiatives are executed with excellence and aligned with our mission to improve patients’ lives. You will drive strategic planning, oversee key initiatives, enhance operational processes, and facilitate cross-functional collaboration. The ideal candidate is a proactive problem-solver with a strong background in digital and technology leadership and exceptional interpersonal...

Employer Vertex Pharmaceuticals Incorporated JOB TITLE Principal Research Associate, Bioanalytical LOCATION 316-318 Northern Ave, Boston, Massachusetts, 02210 OPENINGS 1 DUTIES Conduct bioanalytical assays to support preclinical study sample analysis. Carry out method development and optimization to quantify target proteins. Maintain proper documentation of experiments and support QC data review. Collaborate with cross-functional teams to review study design and interpret results. Prepare technical reports and presentations to document and communicate results. REQUIREMENTS Employer will accept a Master’s degree or equivalent, in applied science, biotechnology or a related field and 3 years of experience in the job offered or...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Associate Director, Consumer Media Strategy and Execution will lead the development and execution of comprehensive media strategies to enhance the digital presence and engagement plan as a critical part of the US Consumer Marketing team within the US Kidney Business Unit. This role will focus on designing the consumer media plan around a focused understanding of the patient journey with disciplined follow through and drive for optimizing patient experience. The ideal candidate will have a strong background in media planning, media buying, analytics measurement, as well as channel selection and optimization. Key Duties and Responsibilities Oversee media planning and media...

We are seeking a talented, self-motivated and collaborative in-vivo pharmacologist to join the integrated pharmacology team supporting late-stage drug discovery. The ideal candidate will have a strong foundation in pharmacology, work with a high degree of independence and be adept at conceptually designing, executing and interpreting in vivo/ex vivo experiments to establish therapeutic proof-of-concept across diverse disease areas. Key Duties and Responsibilities Designs and conducts elaborate, conceptually connected, multi-component in vivo/ex vivo experiments to demonstrate proof-of-concept in preclinical disease models including pharmacokinetic, pharmacodynamic and efficacy relationships. Perform advanced and/or complex experimental assay development and troubleshooting. Collates and interprets complex data...

Associate Director, Consumer Digital Marketing will be responsible for developing and executing digital marketing strategies to enhance the engagement and communication with US immunoglobulin A Nephropathy (IgAN) patients as part of the US Povetacicept Marketing team within the US Kidney Business Unit. This role will focus on creating and implementing the consumer omnichannel communication journeys, including but not limited to display, CRM, social, and search integration while considering the evolving AI landscape. The Associate Director will also serve as the Consumer Digital lead for CRC, ensuring alignment with regulatory and compliance standards. Key Duties and Responsibilities Develop and execute consumer...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

This person will be responsible for the day-to-day administration of the Microsoft 365 Purview and Entra ID platforms, as well as the Veritas Data Insight platform, in a heavily-regulated GxP environment. This person will be responsible for working with business and technical leaders to identify systems containing critical data and labeling them accordingly. S/he will be responsible for creating data protection awareness programs for end-users and using standardized metrics to document compliance. S/he will participate in incident investigations and assist, when necessary, to resolve complex software and hardware problems. This person will be required to follow strict change control processes...

Vertex is seeking an Associate Director (AD) to join the Forecasting, Analytics and Insights team in the North America Commercial organization. The AD will be responsible for delivering commercial insights to inform strategic choices and commercialization decisions for launched and pipeline assets in disease areas such as hemoglobinopathies (e.g., sickle cell disease, beta thalassemia), cystic fibrosis, pain, and other serious diseases. The AD will partner with the US & Canada business units and the Global Commercial Brand teams, to maintain a clear understanding of the overall business and key questions for the programs, and will formulate and execute an insights...

Federal Accounts Lead, US Pain Business Unit Vertex is seeking a highly motivated and experienced Federal Accounts Lead to join our US Pain Business Unit to support our journey to bring forth new options for the treatment of pain. The Federal Accounts Lead will be part of the strategic accounts field team for the US Pain Business Unit, for the commercialization of JOURNAVX in acute pain. We are seeking a candidate who has a strong track record of engaging key DoD and VA decision-makers to drive access and use of innovative pain medicines . The Federal Accounts Lead will report...

Vertex

This role will lead and drive the Sales and Operations Planning (S&OP) process for Casgevy, a commercially launched product within Vertex’s Cell and Gene Therapy portfolio. This is a critical role within the Vertex Supply Chain, that includes the ability to perform complex modeling, utilizing assumptions, demand and capacity to meet both short- and long-term requirements. The Associate Director will be responsible for working with the commercial team to align assumptions and the demand plan, External Manufacturing to work with CDMO’s to align capacity assumptions, Finance, Materials, Quality Control and Regulatory that will culminate in the monthly S&OP process. This...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

The Principal Analyst will serve as a strategic liaison between Marketing stakeholders and technical delivery teams, ensuring that business objectives are translated into actionable technology solutions. This role focuses on enabling and optimizing the Marketing Technology ecosystem—including Marketing Automation, Customer Data Platforms (CDP), and Web technologies—while maintaining compliance with legal and privacy regulations in a highly regulated industry. The ideal candidate combines deep technical expertise with strong business acumen and solution architecture principles. Key Duties and Responsibilities Business Engagement & Requirements Translation Execute the translation of defined business milestones, objectives , and KPIs from Marketing into clear, actionable functional requirements,...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

The Executive Director (ED), North America Commercial Operations leads a team that supports multiple in-line disease areas, supporting each US Business Unit and their respective leadership teams within North America Commercial. The ED oversees 6 district functions Commercial Data Management, Digital Customer Engagement, Field Operations, Marketing Operations, Field Training, and Business Engagement Leads. This position reports to the Vice President, North America Commercial Operations, Insights & Analytics and is located at our headquarters in Boston, MA in the Seaport area. Key Duties and Responsibilities Leads 6 distinct functions Commercial Data Management, Digital Customer Engagement, Field Operations, Marketing Operations, Field Training,...

Employer Vertex Pharmaceuticals Incorporated JOB TITLE Senior Statistical Programmer II LOCATION 50 Northern Ave., Boston, Massachusetts, 02110 OPENINGS 1 DUTIES Codes complex SAS programs (including Macro language, SAS/STAT and SAS/GRAPH) for applications designed to analyze and report complex clinical trial data and for electronic review, exchange, transformation, and submission of data in CDlSC SDTM format; consistently meeting objectives of the study. Performs quality control checks of SAS code and output produced by other Statistical Programmers. Demonstrates proficient knowledge of clinical development and medical data. Solves clinical trial reporting problems and has a proven technical proficiency in...

Through internal audits the Internal Audit Manager will identify risk areas, evaluate business process controls and complete test plans on operational audits. Additionally, this role will provide recommendations to improve the effectiveness and efficiency of operations and business systems. This role will also participate in ensuring that the yearly internal control review is brought to fruition by interacting with SOX testers, other stakeholders, and subject matter experts on special projects and the development and execution of departmental goals. Key Duties and Responsibilities Plans and performs financial, operational and, as applicable, IT audits; reviews related records for compliance with established and...

The Associate Director, GMP Operational Quality will provide leadership and quality oversight for contract testing laboratories (CTLs) supporting Vertex’s biologics and combination product portfolio across development, PPQ, launch, and commercial lifecycle management. This role ensures that analytical testing, method execution, and data generated by external laboratories meet Vertex, global regulatory, and data integrity standards. Key Duties and Responsibilities Serve as the primary QA lead for CTLs supporting release, stability, characterization, and device-related testing for Vertex’s biologics and combination products. Provide quality oversight for analytical method qualification/validation, method transfer, and lifecycle management activities executed by CTLs. Review and approve analytical protocols,...

Employer Vertex Pharmaceuticals Incorporated JOB TITLE Principal Clinical Programmer LOCATION 50 Northern Ave. , Boston, MA, 02110 OPENINGS 1 DUTIES Utilize SAS and other supporting tools to design, write, validate , and maintain programs to meet specifications in a quality, timely and productive manner following standard development procedures. Solid understanding of Clinical data warehouse platform ( Elluminate ), act as a subject matter expert for all the end users. Excellent programming skills to perform all the report development, data analytics and configuration in Elluminate application. Generate and maintain all required documentation, including the development of specifications,...