Vertex Job Trends

As a member of Vertex’s Investor Relations team, the I nvestor R elations Analyst is responsible for key activities supporting quarterly earnings call preparation , quarterly shareholder analyses, investor conference s, consensus reporting , stock charts and analyses, calendar/deliverables prioritization, leveraging AI tools to maintain competitive awareness, and supporting the IR team and Executive Committee as needed. This role provides support for the IR team and key insights for various Finance functions (FP&A, Accounting, BD, etc.). This position is based in our Boston, MA location (Seaport area) and requires a hybrid work schedule with 3 days in office/2 days remote...

Employer Vertex Pharmaceuticals Incorporated JOB TITLE Operational Area Quality Manager LOCATION 50 Northern Ave., Boston, Massachusetts, 02210 OPENINGS 1 DUTIES Responsible for generating performance metrics and identifying trends. Provide QA support of change controls, investigations, CAPA’s and effectiveness checks. Lead meetings as necessary and collaborate with customer groups to ensure quality systems are monitored and established metrics are met. Participates in compliance walkthroughs of the site and help to drive the closure of any observations. Responsible for identifying risks and communicating gaps for process/systems. Participate in continuous improvement of department processes and ensure the team continues to...

The Senior Meetings & Events Planner will be responsible for delivering strategic meeting planning for a variety of meetings independently and with the support of preferred logistics vendors. This role will be skilled in ensuring seamless execution of highly complex events while fostering strong relationships with global teams and suppliers. The ideal candidate will demonstrate problem-solving and interpersonal skills with a global point of view, and partner with cross-functional planning teams to ensure meeting logistics and planned activities are aligned and support the overall meeting goals and objectives. The ideal candidate must possess strong HCP/Compliance knowledge and experience and the...

The External Communications, Senior Specialist is responsible for supporting the team with executing corporate communication programs for Vertex. While part of the Corporate Reputation team this role will also be expected to work with the wider Corporate Affairs team across multiple projects. You will support the delivery of above product activities including awards and recognitions; community affairs activities; executive and senior leader thought leadership planning; corporate social responsibility; and external communications related to culture and values. Responsibilities Support with developing and executing our corporate above brand media activities including (media placements, writing media materials, development of social media copy) Writing...

The Operations, Pricing & Analytics Associate Director leads sophisticated analyses, develops financial models, and generates insights to address strategic questions, business cases and government policy changes for a portfolio of commercial assets. Key Duties and Responsibilities Builds, improves, and manages best-in-class models (i.e; GTN forecast) for commercial assets in the Vertex portfolio Generates insights and leads complex analyses to address strategic questions, business cases, government policy changes in the industry and innovative reimbursement approaches such as value-based agreements throughout product lifecycle Provides a high degree of support for the monthly and annual forecasting process, focusing on the current year and...

We are seeking a strategic and hands-on Director, HR Business Partner to support one or more sub-functions within the Biopharmaceutical Sciences & Manufacturing Organization (BSMO) during a pivotal phase of growth and innovation. In this role, you will be a visible HR leader within the sub-function, serving as a trusted advisor to senior leaders and their teams. You will shape the people and organization strategy, enable business outcomes, and foster a high-performance, agile culture across a regulated manufacturing and technical development environment. This is a senior individual contributor role that leads through influence—orchestrating outcomes across a matrix, aligning cross-functional stakeholders,...

Vertex is seeking a talented and experienced leader to join our Analytical Development (AD) Biologics and Cell and Gene Therapies Team in Boston, MA. The experienced leader will be a member of the AD Leadership Team and will play a central role in advancing our programs and growing our capabilities to support manufacturing and testing of our therapies. The individual in this role will work collaboratively with Research, Process Development, Manufacturing, Quality Control, Regulatory, and Quality functions to develop and innovate next-generation analytical tools for the characterization and release of biologics and cell and gene therapy products. Responsibilities of the...

Vertex is seeking a talented and experienced leader to join our Analytical Development Team to lead CMC analytical development for Biologics. The experienced leader will play a central role in advancing our biologics portfolio by building analytical development strategies through a combined internal and external network. The individual is responsible for providing strategic and technical leadership for analytical development of biologics from the discovery interface to first license approval and beyond, such as post approval 2nd generation product development. The individual is expected to lead multiple analytical matrix team leaders, in defining and execution analytical development strategies with phase appropriate...

As a key Team Manager and leader in the Strategic Sourcing function, the Director, Strategic Sourcing Enterprise Third-party Risk Process & Governance leader is responsible for leading the operational execution of the end-to-end third party risk process as a key member of the Central Risk Management team. This role is responsible for shaping, driving and managing central third-party risk management processes, supporting cross-functional teams, and ensuring consistent application of risk policies and procedures across the third-party/supplier life cycle. The Director will collaborate closely with business owners, risk SMEs, sourcing teams and the rest of the Central Risk Management team to...

Principal Data Scientist, MSAT – Data Science and Automation Engineering, Vertex Pharmaceuticals (Boston) Vertex MSAT team is seeking a Principal Data Scientist to join a growing team in support of commercial Cell and Gene Therapy programs. This position will be responsible for supporting and providing technical support in alignment with defined program priorities pertaining to data acquisition, analysis, trending, visualization, and reporting. Key Responsibilities Identify and develop technical solutions to enable program and company goals. Lead/support development of data trending visualizations using Statistica and for process parameters Lead/support the Development of Routine Data Visualization charts and tools Develop scripts for...

The Territory Account Manager is responsible for plan execution, delivering sales performance, and product promotion in their specified territories. (Territory may change upon the needs of the organization). The TAM must maintain a high level of knowledge within the disease states and product labeling. Activities include disease state and product education to referring HCPs, collaboration with internal and external stakeholders, and shaping and executing sales strategies. The individual in this role must be goal-oriented and accountable for their individual performance, while acting in a professional and compliant manner. This role will drive business growth through effective sales strategies, HCP engagement,...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

This role oversees process compliance within the Clinical Budgets Team, including documentation, training, and implementation. This role also champions compliance with Vertex's Global Spend Transparency Policy across Global Medicines Development and Medical Affairs (GMDA). The focus across all initiatives will be on continual process improvement to drive effectiveness, standardization, and improved productivity. Key Duties and Responsibilities Oversees technology and processes for Global Spend Transparency policy compliance Training of Global Spend Transparency reporting requirements to external vendors and internal stakeholders Presentation of Global Spend Transparency data to leadership Manages time-sensitive activities, ensuring all deliverables are completed on schedule, with clear ownership...

The Senior Director, Strategic and Portfolio Finance is a key leader within Vertex’s Finance organization, responsible for driving strategic decision support across the enterprise portfolio and leading long-range financial planning processes. This role defines and delivers the vision for portfolio decision-making, integrating financial and non-financial metrics to enable informed trade-offs and strategic alignment. The position plays a critical role in ensuring consistent understanding of value creation, investment, and uncertainty across Vertex’s portfolio. Key Duties and Responsibilities Develop and implement an enterprise portfolio management framework to support strategic decision-making and prioritization. Collaborate with cross-functional stakeholders to define common financial and non-financial...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Formulation Research Scientist will work with other scientists dedicated to advancing drug candidates from exploratory development through commercial line extension in a Quality by Design (QbD) environment using lab based and computational tools to design and select dosage forms and manufacturing process. Key Duties and Responsibilities Develop dosage forms for clinical and commercial use Develop stable and bioavailable formulations for different stages of development (e.g., solution/suspension based formulations, amorphous pharmaceutical systems into solid oral dosage forms, parenterals, etc.) Help to design, execute experiments and analyze, and present results Generate data for project progression and regulatory filings, conduct optimization and...

The Medical Affairs Associate Medical Director will provide medical leadership for the Medical Department in the Pain therapeutic area. This role will be accountable for working with the medical team for North America, for the development and implementation of the North American Medical strategy and plans and will work in partnership with cross functional team colleagues to ensure access to company’s products, develop and implement cross functional country plans aligned with patient, HCPs’ and broader corporate needs. This role is responsible for building and encouraging scientific excellence within the team and engaging in close partnerships with HCPs, scientific societies and...

The Territory Account Manager is responsible for the geography between Bradenton and Naples, Florida, plan execution, delivering sales performance, and product promotion in their specified territories. (Territory may change upon the needs of the organization). The TAM must maintain a high level of knowledge within the disease states and product labeling. Activities include disease state and product education to referring HCPs, collaboration with internal and external stakeholders, and shaping and executing sales strategies. The individual in this role must be goal-oriented and accountable for their individual performance, while acting in a professional and compliant manner. This role will drive business...

The Clinical Trial Management Principal is responsible for leading global or regional-based activities on complex clinical trials across a range of study phases (Phases 1 through 4, including Real World Evidence trials) and therapeutic areas. In the global role, the Clinical Trial Management Principal leads the global cross-functional Study Team, ensuring that deliverables are met, quality is maintained throughout the lifecycle of the trial, and the study budget is maintained. The role is also responsible for contributing to Clinical Trial Management department initiatives, often as leader. Key Duties and Responsibilities Accountable for execution of assigned clinical trial(s) at the global...

The Director of Financial Planning and Analysis, Biopharmaceutical Sciences and Manufacturing Operations (BSMO) is a key member of Vertex's Financial Planning & Analysis team. This role will partner closely with Commercial Manufacturing and Tech Ops (CMTO), Commercial Finance and Disease Strategy Team (DST) Finance in support of our Cell and Gene Therapies portfolio, with a specific focus on CASGEVY, the first-ever approved CRISPR-based gene-editing therapy used to treat Sickle Cell Disease and Transfusion-Dependent Thalassemia. This role will have the opportunity to work across the organization by providing analysis and insights that will drive key decisions around manufacturing strategy and resource...

Vertex is seeking a hands-on, strategic, and collaborative Director of Talent Acquisition to lead talent acquisition efforts across all U.S. Commercial Business Units. The ideal candidate is a bold, business-minded talent advisor who thrives in a fast-paced, matrixed environment and is passionate about building teams that drive commercial excellence. The Director will serve as a trusted partner to senior leaders, shaping and executing talent strategies that align with Vertex’s mission to transform lives. Key Duties and Responsibilities · Own and actively manage a desk of high-impact requisitions, including key and business-critical roles, ensuring timely and high-quality outcomes. · Drive and...

Vertex currently operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Pain, and the first CRISPR-based, gene therapy for sickle cell disease and transfusion-dependent beta thalassemia. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Type 1 diabetes, APOL-1 Mediated Kidney Disease, IgA nephropathy, Duchenne Muscular Dystrophy, and Alpha-1 Antitrypsin Deficiency (AATD). The Regional Access and Reimbursement Associate Director will help ensure appropriate access and reimbursement of Vertex cellular...

The Associate Director, Congress and Ad Board Lead, US Kidney is responsible for driving congress planning and advisory boards for povetacicept and inaxaplin to support our launches in IgA nephropathy (IgAN) and APOL1-mediated kidney disease (AMKD). This person will lead the planning and booth presence at local, regional, and national conferences and medical society meetings. Additionally, this person will be responsible for engaging with Key Thought Leaders (KTLs) to plan and execute ad boards and strategic council meetings, ensuring the collection and pull through of insights to inform marketing strategy. We are seeking a candidate that has a strong track...

The Biomarkers Senior Principal Research Scientist (Associate Director) is an independent leader with advanced scientific knowledge and expertise in biomarker development who develops and implements the clinical biomarker strategy for one or more programs and implements the biomarker plan during clinical development with no/minimal guidance. Experience in authoring and supporting regulatory filings and applicable areas of these filings is required. The incumbent is an expert in the field of assay development and validation and works with a team and several external CROs to ensure fit-for-purpose validation of biomarker assays. The incumbent candidate is a specialized technical expert in specific areas...

The Senior Manager, Thought Leader Programming and Operations, US Kidney , leads the planning, management, and implementation of peer to peer (P2P) educational events. This role will initially cover two pipeline assets within the US Kidney Business Unit to support launches in IgA nephropathy (IgAN) and APOL1-mediated kidney disease (AMKD). The Senior Manager will ensure successful and compliant execution of a broad range of activities such as speaker programs, ad boards, congresses, and other Thought Leader engagements. We are seeking a candidate who has a strong track record of managing US commercial programming with Thought Leaders, collaborating with field sales...

We are seeking a visionary People Research Associate Director to lead the design and execution of high-impact research initiatives that shape workforce strategy and elevate organizational effectiveness. This role demands deep expertise in experimental methods, program evaluation, and storytelling with data. The People Research Associate Director will hold a PhD in a relevant field and bring a strong track record of translating complex research into actionable insights for senior leadership. Key Duties and Responsibilities Lead End-to-End Research Design Architect and execute research studies to evaluate the effectiveness of HR programs, policies, and interventions. Plan, design and conduct experiments to understand...

The Director, Speaker Bureau and Content Lead, US Kidney is responsible for setting up and leading the speaker bureau and developing all approved content to support our launches in IgA nephropathy (IgAN) and APOL1-mediated kidney disease (AMKD). Additionally, this person will map and prioritize all Key Thought Leaders (KTLs), Digital Opinion Leaders (DOLs), and Centers of Excellence (COEs) to support the KTL engagement strategy and identify opportunities for educational partnerships. We are seeking a candidate who has KTL and speaker bureau experience and a background in developing engaging content for peer-to-peer forums. This role reports to the Head of Market...

Are you an accounting or finance professional who is passionate about process innovation, optimization and supporting positive business outcomes? Vertex is seeking a hands-on, experienced leader with deep process optimization expertise to join our Global Accounting organization. The Senior Director, Record-to-Report (R2R) Strategy & Optimization will be accountable to set the strategy and roadmap for our R2R process improvement journey, for measuring our performance and ensuring related stakeholder needs and enterprise goals are consistently met. This newly established role is ideal for a motivated leader who can contribute to our strategic direction, effectively align diverse stakeholders, foster collaboration, and deliver...

General/ Vertex

General/ Vertex is in an exciting time of growth and innovation, and technology and data are valued as strategic assets. The Commercial Technology team in the Data, Technology and Engineering (DTE) organization is seeking an experienced technology leader to head the strategy, planning and delivery of key technology capabilities to support Vertex’s North America Kidney and CF business units and Patient Services function. The Business Unit team includes sales and marketing for each disease area, and the Patient Services team support North America patient services for all disease areas. Vertex is in a transformational period of growth; we are investing...

The People Analytics Sr. Manager will play a pivotal role in shaping Vertex’s HR data strategy by leveraging advanced analytics, experimentation, and storytelling to drive data-informed decisions across the employee lifecycle. This role will partner closely with HR and business leaders to uncover insights, design experiments, and communicate findings that influence talent strategies and organizational effectiveness. The People Analytics Sr. Manager will be focused on building scalable data and AI solutions and translating research and analytics into actionable business insights Key Duties and Responsibilities Lead the design and execution of people analytics projects that support strategic HR initiatives, including talent...

The Commercial Pain Training Senior Manager will help enhance the skills and knowledge competencies of customer-facing teams, including Field Sales, Account Managers, and Guidance and Patient Support (GPS). This role will be primarily responsible for developing and executing training programs for the field teams and managing the day-to-day Commercial needs for the Learning Management System (LMS) administration. Key Duties and Responsibilities Partner with commercial marketing, sales, account management, and GPS to identify training needs and recommend solutions Develop, implement, and facilitate training programs and workshops as required Identify, design, create and facilitate effective content that improves the desired outcome for...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Medical Affairs Medical Director will provide medical leadership for T1D and will be responsible for developing the medical plan and its execution for T1D. This role will collaborate closely with cross-functional groups to ensure that medical strategies are aligned with broader corporate and key stakeholder needs as well as ensuring the voice of the patient and medical community is integrated into product strategies. Technical competencies and enterprise-level critical thinking abilities are required. Key Duties and Responsibilities Under direction of the Medical Affairs Leader supports development of plans such as medical, launch and evidence generation plans Critically interprets scientific data,...

The Senior Manager, Contract Administration will report to the Director, US Market Access Contracting & Pricing in support of the US Market Access Contract Operations team with various deal governance activities (scheduling, proposal log maintenance, meeting minutes, etc.), Fair Market Value “FMV” governance, contract timeline tracking/reporting, contract clause library upkeep, contract prioritization tracking/reporting, and peer review of contract drafts and SOWs. The role is highly visible and will help build efficiency within the team and provide critical support across the end-to-end contracting process. Key Duties & Responsibilities Support deal governance committees Schedule meetings based on submitted agendas, maintain proposal...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex is seeking an experienced Associate Director to lead the day-to-day operations of our global End User Compute (EUC) platforms with a focus on end user experience of the highest quality. This role will focus on Modern Workstation Engineering & Architecture to deliver secure, compliant, and seamless Windows and Mac workstation and mobile experiences across Vertex’s regulated life sciences environment. The successful candidate will drive operational excellence, governance, lead offshore delivery teams, and shape the future of EUC in the age of AI-driven transformation. Key Duties and Responsibilities Lead daily operations of global EUC platforms, ensuring reliability, seamless end user...

The Compliance Associate Director assists in implementing and further enhancing the anti-corruption/anti-bribery Compliance program. Reporting to the Executive Director Head of Global Compliance Program Strategy, Assurance and Management, the Compliance Associate Director will be responsible for executing compliance-related investigations and supporting the company’s global healthcare fraud and abuse assurance program and activities, including auditing and monitoring, both transactional and live. The Compliance Associate Director will serve as the initial point of contact for business colleagues for these activities, will support department initiatives globally and must have knowledge of the biotechnology/pharmaceutical industry, anti-bribery/anti-corruption laws, and experience executing compliance-related investigations as well...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Director, GDP Operational Quality is r esponsible to partner with Trade Operations to support the distribution of Vertex’s commercial product portfolio. The role is responsible for oversight of team activities, development of personnel and ensuring timely completion and quality of deliverables/goals within their remit. The role supports GDP quality operations for all distribution activities within the US; key stakeholders include Trade Operations, Vendor Quality Management & Quality Compliance. Key Duties and Responsibilities The responsibilities of this position may include, but are not limited to, the following Primary quality partner for Vertex US Trade Operations organization, providing quality input and...