Vertex Job Trends

Vertex Pharmaceuticals, Inc. is seeking a highly skilled and proactive Senior Research Associate to join our Human Cell Core, contributing to the development and execution of advanced human cell models at scale. The successful candidate will work in a team setting, maintaining and expanding primary human cells at scale and operating automation-enabled cell culture platforms. Success in this position requires a high degree of reliability, attention to detail, adaptability, problem solving skills and ability to work in a team-oriented environment. Key Responsibilities Work collaboratively as a team to maintain and expand primary human cells at scale Operate state-of-the-art instrumentation and...

We are seeking a dedicated Principal Data Engineer with a passion for pharmaceutical research , to lead and manage our critical Data Engineering team as they strategically enable scientists across Vertex with data . As part of the Data & Software Engineering (DSE) Team , you will be responsible for developing , curating, and maintain ing data assets that enable our scientists to make timely , informed, and critical decisions. . You will work closely with data scientists , data engineers, and platform engineers to scale the Vertex Data Platform , which is Vertex’s cutting edge technology ecosystem for Data...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced senior analyst with a passion for supply solutions, to join our team and drive our digital transformation...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced senior analyst with a passion for External manufacturing solutions, to join our team and drive our digital...

MBA Summer Associate, Commercial The Vertex MBA Summer Associate Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our internship program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are fearless" is in everything we do. Each summer, top MBA candidates from business schools around the world find all this and more through our MBA...

Vertex’s Data, Technology and Engineering (DTE) organization is seeking a Technology Portfolio Management Director to join our Project Management and Strategic Operations (PMSO) team. Project Management and Strategic Operations is charged with streamlining and simplifying the work of our data and technology teams and ensuring the successful deployment of new technologies across our global enterprise. The Director, Technology Portfolio Management will report to our Senior Director of Project Management and Strategic Operations and partner directly with our Chief Information Security Officer and Vice President, Data & Software Engineering to oversee the Information Security and Data & Software Engineering project portfolios...

Job Summary Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. The role is as a Senior Manager within HEOR’s Modeling & Analytics Center of Excellence (CoE), a designated group within the HEOR team that provides strategic and technical support to HEOR, Market Access & Pricing, and the broader commercial organization. The main responsibility of the Senior Manager will be to support the HEOR disease/asset teams in real-world observational and claims data research activities. The Senior...

The Regional Field Leader, Associate Director will be responsible for the oversight of an assigned region within the US Pain Business Unit. Regional Field Leaders (RFLs) will manage a team of 8-10 field-based reps; account managers and territory managers. Pain Territory Account Managers (PTAMs) focus on driving and pulling through hospitals/health system volume and access, expand activation and breadth of prescribers within the hospital setting. Pain Territory Business Managers (TBMs) focus within the PTAM’s surrounding community, calling upon PCPs, oral surgeons, and selected specialties—to broaden reach and accelerate appropriate, on label adoption within these community targets. The RFL reports into...

We are seeking a strategic, influential, and agile HR Business Partner Director to lead talent strategies for key Global Medicines Development (GMDA) functions at Vertex . This Director will play a critical role in achieving the GMDA vision of enhancing leadership, driving innovation, enabling top-tier execution, and integrating technology to achieve superior performance across a diverse development pipeline. This role will serve as a trusted advisor to GMDA leaders and their leadership teams, shaping organizational design, culture, and workforce strategies that enable clinical development innovation, execution and long term pipeline success . Reporting to the Lead HRBP for the Chief...

The Process Chemistry Principal Scientist is technically self-reliant with an extensive track record of accomplishments and will identify and solve complex problems repeatedly across a number of critical and diverse projects. This role will serve as an emerging technical expert in the field and provide reliable and valuable advice to project teams on a regular basis. Key Duties and Responsibilities Designs and performs sophisticated, technically challenging experiments, efficiently and independently ensuring compliance with applicable regulations and SOPs Generates effective hypotheses to pursue project goals and sets new experimental direction Identifies broad implications of results and their impact on overall study...

The Associate Director, Biostatistics will perform sophisticated scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with minimal guidance and mentoring on new and complex issues. The incumbent will completed work in a resourceful, self-sufficient manner and create alternative approaches to achieve desired results. The incumbent is capable of independent strategic and technical contributions. The incumbent should possess a good knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. Key Duties and Responsibilities Conducts all scientific and operational statistical work for multiple clinical trials, observational studies, or real world data (RWD)...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced senior analyst with a passion for intelligent orchestration solutions, to join our team and drive our digital...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced senior analyst with a passion for intelligent manufacturing solutions, to join our team and drive our digital...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced senior analyst with a passion for supply chain planning solutions, to join our team and drive our...

The AI and Real-World Analytics Senior Manager will play a pivotal role in leading and advancing the RWA team’s AI and automation capabilities. This role will focus on driving the development and optimization of the real world data analysis processes. The position will involve deep diving into Real-World Data (RWD) to generate data expertise, actionable insights, and optimal data use strategies to support business objectives. The position is responsible for identifying opportunities within the team to enhance automation, standardization, and simplification and partnering with leadership to prioritize them. Then they will gather requirements, and either build agents using enterprise low/no...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Principal Research Scientist, Tissue Engineering Location Vertex Pharmaceuticals, Boston (Onsite) Vertex Pharmaceuticals is seeking a highly motivated and innovative scientist to join our Human Assay Technologies department in Boston as a Principal Research Scientist - Tissue Engineering. This lab-based role offers an exciting opportunity to lead tissue engineering and technology innovation by developing novel measurement platforms for complex cell models. The successful candidate will have a proven track record of engineering cutting-edge solutions to drive biological insights from 3D organoid models or organ-on-a-chip technologies, with a focus on advancing drug discovery. The ideal candidate will bring a strong background in...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Policy & Alliance Development Associate Director will support the strategy and execution of US (United States) Public Affairs (USPA) activities , with initial focus in our pain and kidney areas . This role will work within Public Affairs as well as cross- functionally with other internal Vertex functions, including commercial, medical, R& D and legal, to ensure alignment and progress around our corporate goals and objectives . Key Duties and Responsibilities Serves as the primary liaison to the USPA State Government Affairs (SGA) t eam on state policy work . S upports identification of SGA opportunities to advance pain...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Background and Vertex operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Casgevy, a gene therapy for sickle cell disease and beta-thalassemia and Journavx, a novel new treatment for moderate to severe acute pain. Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in kidney diseases, Type 1 diabetes, among others. Povetacicept is a highly potent and effective dual antagonist of BAFF and APRIL pathways with potential best-in-class efficacy in patients with IgA nephropathy (IgAN). IgAN is...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Pain Territory Business Manager (TBM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. The TBM reports into a Regional Field Leader and serves as a field representative for JOURNAVX within the community setting. The TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex is seeking a strategic Senior Director to lead AI Product Management within our Commercial Technology organization. This role will be responsible for building and managing a portfolio of high-value commercial AI products that automate operations, accelerate patient access, and enhance customer experience. The Senior Director will define and drive the AI strategy, lead the development and adoption of agentic AI-powered solutions, and collaborate closely with business engagement and platform teams to deliver measurable value. A key focus will be on defining and tracking the impact of AI investments, fostering upskilling and capability building across the functional teams to ensure...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex Pharmaceuticals is looking to hire a Commercial Training Associate Director, Pain on a full-time basis. The AD will report to the Head of Pain Training to develop training materials/curriculum and enhance the skill and knowledge for our US field teams for Pain. The ideal candidate must possess a unique blend of customer-facing field & pharmaceutical training experience, but most importantly scientific aptitude that will enable them to lead through science. The individual must be a strong collaborator to work cross-functionally within the US Commercial Team (Sales, Marketing, Managed Markets) but more importantly across the entire organization (Medical Affairs, HR,...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex is a global biotechnology company that invests in scientific innovation. The Data, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. Role Overview We are seeking a data driven, scientifically literate, and technically skilled Principal Engineer to serve as the Automated Data QC and Reporting...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Senior Manager, GxP Strategic Document Partner supports the Associate Director of GxP Quality Document and Records Management by managing, assessing, and delivering high-impact, compliant documents and records management solutions in alignment with quality objectives, regulatory standards, and business priorities. The Senior Manager serves as a strategic document partner for assigned area(s) and/or quality system(s), leading document impact and needs analyses and partners with the business to lead Global document initiatives, supporting a functional document hierarchy which integrates the development, maintenance, and distribution of critical documents that support the organization’s strategic goals and initiatives. This role requires expertise in consulting,...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

We are seeking a unique individual with a passion for data and AI technology who can help our team drive forward enterprise-scale AI adoption of our data & AI platform. Vertex Pharmaceuticals is in a transformational period where we are accelerating our capabilities, technologies, and data to augment our scientific mission, enable Vertex to grow in scale, and continue to be on the forefront of science, medicine, and technology. As part of this effort, it is critical that users have data “at their fingertips”, with the patterns and technology to support AI adoption at scale. As a Senior Principal AI...

Job Posting Title Senior Manager, Strategy & Operations Market Access Strategy The Senior Manager, Strategy and Operations, US Market Access Strategy is a key partner and advisor to the VP US Market Access Strategy and Market Access Strategy Leadership Team (MAS-LT) on a variety of strategic, operational, and organizational matters. The role requires both strategic thinking as well as the ability to drive project management, and operational execution through preparing, implementing, and effectively managing tactical initiatives. The ideal candidate is a highly motivated and highly organized individual with exceptional emotional intelligence, communication skills and judgment with the ability to...

The Patient Support Communications Senior Manager, Kidney will be responsible for the development and execution of patient and HCP-focused materials that will support our build out of our kidney patient support program(s). A deep passion and curiosity in understanding and supporting the challenges patients face in their lives is imperative. General/ The Patient Support Communications Senior Manager, Kidney is part of the communications team and participates in the day-to-day execution of the patient communications strategy that supports those enrolled in our patient support program. The individual will support the development of our executed communication strategy by developing and/or updating materials...

The Associate Director of Early Pipeline Forecasting & Process will lead commercial forecasting efforts across multiple pre-clinical and early clinical programs, shaping Vertex’s understanding of potential opportunities long before pivotal data becomes available. This individual will build structured, assumption-driven models, stress-test evolving inputs, and synthesize insights across scientific, clinical, competitive, and market research sources. They will collaborate closely with marketing science and external vendors to ensure primary and secondary market research is appropriately interpreted and incorporated into forecasts. The role serves as a key voice across the broader Vertex portfolio—coordinating portfolio-wide analytics during the long-range planning (LRP) cycle, aligning assumptions...

The Senior Director, Project Management and Strategic Operations, is a key leadership role that will provide strategic leadership and direction to the advancement of the framework, capabilities, and sustainability of the compliance function in driving leading practices and keeping pace with the evolving organization and industry. This role will provide strategic direction and oversee the vendor qualification and compliance oversight program across areas ensuring effectiveness of risk management strategies across third parties and internal vendor management. This role will also provide strategic direction and oversee advancement of the inspection readiness framework with responsibility for strategic management and hosting of regulatory...

As a key Team Manager and leader in the Strategic Sourcing function, the Director, Strategic Sourcing CoE Programs & Initiatives Leader is responsible for leading the strategic sourcing organizational through designing and driving key programs for value delivery and organizational AI readiness in partnership with the functional sourcing teams, business, DTE and other key stakeholders, elevating sourcing and procurement impact to the enterprise. The role provides people leadership to elevate the capabilities of the sourcing team, and has responsibility to help shape the future of an AI centered operating model. The ideal candidate understands Vertex systems and processes, is a...

The Director, Quality Analytics is accountable for advancing the Quality Analytics Center of Excellence by delivering trusted, decision‑grade insights across Quality and GxP domains. This role leads a team that designs and scales metrics, dashboards, and advanced analytics to strengthen quality governance, operational oversight, and continuous improvement across modalities and product lifecycle stages. This role is a people manager, responsible for building and developing a high‑performing team, establishing clear priorities and operating rhythms, and ensuring analytics and AI solutions are implemented in a controlled, compliant manner suitable for regulated environments. The role partners cross‑functionally to improve data quality and reliability,...

The Senior Director, Biostatistics will independently perform highly scientific statistical functions in support of a company therapeutic area or areas on new and complex issues. The incumbent will complete work in a resourceful, self-sufficient manner and create alternative approaches to achieve desired results if needed. In addition, the Senior Director provides independent strategic and technical contributions. The incumbent should possess an excellent knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. As a people manager within the organization, may have financial accountabilities and human resource responsibilities for assigned staff. Key Duties and Responsibilities Defines and implements...

Vertex is seeking an experienced and energized consolidation leader with accounting systems and process expertise to join our Global Accounting organization . T he Associate Director, Accounting Systems & Consolidation is responsible for overseeing the team’s performance of monthly consolidation tasks , supporting various process improvement and optimization initiatives, and collaborating with the IT department to enhance and upgrade key accounting systems . The ideal candidate is passionate about leveraging technology to streamline operations, improve efficiency, and modernize accounting processes . Key Duties and Responsibilities Oversee team execution of the global consolidation process, focusing on accuracy and timely preparation of...

The Patient Support Communications Manager, Kidney will be responsible for the development and execution of patient and HCP-focused materials that will support our build out of our kidney patient support program(s). A deep passion and curiosity in understanding and supporting the challenges patients face in their lives is imperative. General/ The Patient Support Communications Manager, Kidney is part of the communications team and participates in the day-to-day execution of the patient communications strategy that supports those enrolled in our patient support program. The individual will support the development of our executed communication strategy by developing and/or updating materials for patients...

Role Overview The Sr. Director, Commercial Technology Business Engagement Leader – Kidney & Patient Services is responsible for executing and operationalizing commercial technology capabilities in direct support of the North America Kidney Business Unit and the Patient Services Program. Reporting the Executive Director, US Commercial Technology this role acts as the day‑to‑day technology leader embedded with Kidney commercial and patient services leadership, accountable for translating business priorities into deliverable roadmaps, funded initiatives, and reliable operations. The Sr. Director ensures that technology solutions—spanning CRM, digital engagement, data, analytics, and AI‑enabled workflows—are implemented effectively, adopted by the business, and operated reliably within...

We are seeking a dedicated and skilled Senior Research Associate to join our Tissue Dissection Group within the Molecular & Cell Biology team in San Diego. The successful candidate will play a critical role in generating high-quality cells from primary human tissues, contributing to various Vertex research programs. This position requires expertise in human tissue dissection, a commitment to excellence, and a deep respect for the gift of donated human tissues. Key Responsibilities Perform dissection of human tissues, including dorsal root ganglia (DRG), lung, and precision-cut tissue slices. Develop and optimize dissection workflows and methods to enhance efficiency and quality....

Vertex currently operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Pain, and the first CRISPR-based, gene therapy for sickle cell disease and transfusion-dependent beta thalassemia. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Type 1 diabetes, APOL-1 Mediated Kidney Disease, IgA nephropathy, Duchenne Muscular Dystrophy, and Alpha-1 Antitrypsin Deficiency (AATD). The Regional Access and Reimbursement Associate Director will help ensure appropriate access and reimbursement of Vertex cellular...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Job Summary Vertex is seeking a highly motivated and experienced Associate Director, Quality Control to join our External Manufacturing, Cell and Genetic Therapies (CGT) team. This role is pivotal in driving quality excellence and operational efficiency across our commercial CGT manufacturing sites and testing facilities. The successful candidate will lead key quality initiatives, develop and execute lifecycle management (LCM) strategies, and champion digital transformation within the Quality Control (QC) function. This is a hybrid role, offering a dynamic and collaborative work environment. Key Responsibilities Develop and execute Lifecycle Management (LCM) strategies to ensure continuous improvement, scalability and compliance across QC...

The Commercial Field Strategy & Execution Associate Director assesses business opportunities and challenges within the kidney field sales business unit. This role entails collaborating with various customer-facing teams and internal stakeholders to maximize commercial opportunities while meeting assigned performance goals. This individual will focus on driving brand performance by leading the development, integration, and implementation of the business planning process for the commercial field team. The role involves close collaboration with marketing, market access, and other key stakeholders to develop and execute strategies within the kidney BU. The Commercial Field Strategy & Execution AD will serve as a liaison between...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Director, Clinical Trial Management is responsible for the planning, oversight, and execution of study and program-level deliverables across a range of study phases within one or more therapeutic areas to ensure corporate goals are met. This role often has responsibility for complex therapeutic areas with multiple compounds under simultaneous clinical development. This role will also manage a high performing global team of Clinical Trial Managers in the fast-paced and expanding Global Clinical Operations (GCO) organization, and may also manage individuals at the Associate Director level who also have program-level responsibilities. This position has a strong affiliation with the GCO...

Qualified candidates Must live within a 25 mile radius of Kissimmee / Lakeland, Florida areas. The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within...

As the Field Analytics and Reporting Associate Director , you will be responsible for supporting all field analytics to support the current and upcoming product launches for Vertex. This role reports to the Director of Field Analytics in North America IACO (Insights Analytics & Commercial Operations). This role will support strategy, design, roadmap planning, delivery, and adoption of all analytics across all field roles within the Strategic Customer Engagement Team including Field Account Managers, Regional/Area Managers, Strategic Account Leads, and Virtual Field Representatives. This role will also serve as a critical team member for the Business Unit Analytical Support team...

Vertex is seeking a talented leader to join our US Kidney Business Unit to support our aspirations of bringing Povetacicept and Inaxaplin , Phase 3 investigational therapies that have the potential to transform lives across multiple serious diseases, to patients. The Senior Director, Patient Support Lead will be key to creating the necessary processes, systems, infrastructure, and operations for the Patient Support organization within the US Kidney Business Unit. They will develop the launch strategy , define the appropriate patient support model, recruit and develop a high-performing patient support team and ensure execution of launch activities. This role is a...

The Associate Director, Portfolio Management R&D Quality (RDQ) reports to the Head of Analytics & Centers of Excellence (ACE) and provides operational leadership and oversight for the successful execution and delivery of all R&D Quality (RDQ) initiatives across the business portfolio. Supporting all RDQ and Quality Assurance (QA) business units, these initiatives focus on implementing effective business tools, systems, and processes to establish a robust governance model and a data‑rich environment that drives operational excellence, process optimization and automation, informed study oversight, transparent and proactive portfolio and program governance, and strategic, evidence‑based planning and prediction. With additional responsibilities for staff...

The Senior Director, Regulatory Submission Management champions functional and cross-functional project and submission management excellence. The incumbent is expected to apply deep subject matter expertise in project and submission management to lead and identify opportunities, shape objectives and drive execution of key functional and corporate objectives. This role will be responsible for driving timeline risk mitigation and contingency planning. Key Duties and Responsibilities Provide strategic and operational project, submission and program leadership activities at all stages of the lifecycle (initiation through closeout). Drive communication cross-functionally and with senior leaders on project, submission and program planning topics including timelines, status, risks...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex

Vertex is seeking an experienced commercial leader to implement field sales and non-personal promotion tactics in support of the Pain Business Unit (BU). The Customer Strategy & Execution Lead (CSEL) will partner with North America commercial organization to implement the go-to-market (GTM) strategy and deliver customer solutions that meet the business needs. This role will work directly with the BU stakeholders, Field Operations Leads, Digital Operations Leads, Customer Data Management, and technical stakeholders to optimize HCP customer experience. This role reports to the Director, Customer Strategy & Execution Lead. Key Duties and Responsibilities Partner with key business leaders to understand...

The Medical Affairs Strategy Medical Director will provide medical leadership for the Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of IgA Nephropathy (IgAN), that has best-in-class and pipeline-in-a-product potential across a variety of autoimmune diseases. This role will be responsible for developing the medical strategy and medical plan under the direction of the VP/Executive Director, as well as executing against the medical plan encompassing the pove programs. This role will collaborate closely with cross-functional groups to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs,...

The Executive Director (ED), North America Commercial Operations leads a team that supports multiple in-line disease areas, supporting each US Business Unit and their respective leadership teams within North America Commercial. The ED oversees 5 district functions Commercial Data Management, Field Operations, Marketing Operations, Field Training, and Business Engagement Leads. This position reports to the Vice President, North America Commercial Operations, Insights & Analytics and is located at our headquarters in Boston, MA in the Seaport area. Key Duties and Responsibilities Leads 5 distinct functions Commercial Data Management, Field Operations, Marketing Operations, Field Training, and business engagement leads in support...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Commercial Data Management Senior Manager, Pain, is responsible for contributing to the coordination, design and delivery of the commercial data activities that enhance customer engagement and facilitate data driven decision making for the Pain therapy business unit. Key Duties and Responsibilities Acts as an advisor and coach for and collaborates with the governance team(s) Manages data services vendors Supports the training of internal teams on processes and procedures, including CRM Collaborates with Global Information Systems (GIS) team regarding implementation of fixes and enhancements Partners with Sales and Marketing teams to manage and administer content update requests Manages HCP-to-HCO affiliations...

We are seeking an innovative and highly motivated Senior Scientist to lead discovery-stage development of targeted lipid nanoparticle (LNP) platforms. This role will drive receptor target identification and validation, establish high-throughput ligand conjugation workflows, and develop scalable assay systems to enable systematic screening of targeted LNP constructs. The successful candidate will build a modular, data-driven targeting engine capable of evaluating single and multi-ligand strategies across multiple cell types and therapeutic indications. This is an onsite position in San Diego. KEY RESPONSIBILITIES Receptor Target Identification & Validation Identify and prioritize cell-surface receptor targets aligned with disease biology and delivery feasibility. Integrate...

Vertex

The Senior Administrative Assistant provides experienced office/business support to a department. The Senior Administrative Assistant generally reports directly to a(n) Country Manager, Executive Director or Vice President-level manager. Key Duties and Responsibilities Manages calendars for assigned personnel, including meeting scheduling (both internal and off-site meetings), accepting/declining invites, meeting prioritization, securing conference rooms, ordering catering and "day-of" logistical and administrative support Serves as a departmental resource for Vertex's internal technologies (i.e; Procurement, SharePoint, Concur, Vertex U, VLearn, etc.) Exchanges and integrates information from stakeholders into departmental reports Books flights/hotels, completes expense reports, and arranges team lunches/dinners and offsite meetings for assigned...

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group in Boston, MA. The Health Economics & Outcomes Research Senior Manager will participate in the development and execution of Health economics and outcomes research studies in support of Vertex's products. This position reports to the Director HEOR, Pain. Key Duties and Responsibilities Executes HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value Provides...

The Senior Administrative Assistant provides experienced business support to the Quality department, reporting directly to a Vice President. The role is responsible for core administrative duties including calendar management, budget planning, and partnering with other assistants to drive continuous improvement. A primary focus of this position is establishing and leveraging digital technologies and AI to enhance task execution and optimize departmental workflows. Key Duties and Responsibilities Ensures seamless execution of day-to-day activities including proactive calendar management, meeting prioritization, and logistical support. Serves as a departmental resource for internal technologies such as SharePoint, Procurement, and Concur. Books travel logistics and completes...

The Patient Safety Associate Medical Director will provide medical safety expertise, state of the art pharmacovigilance, and safety risk management for assigned products (marketed or in development). This role will optimizes patient safety of Vertex products and maintenance of compliance with the Pharmacovigilance regulations of Regulatory Agencies around the globe, through the effective and timely completion of Safety activities through the product life cycle. Key Duties and Responsibilities Provides medical safety expertise, state of the art pharmacovigilance, and safety risk management for assigned products (marketed or in development) Responsible for the safety assessment activities of assigned products under the supervision...

Reporting to the Senior Director, Contract Operations, this role is responsible for the lifecycle management process of agreements within the US Market Access Organization (Commercial and Government (ex Medicare Advantage and Part D)) Full Line Wholesalers, Specialty Distributors, Specialty Pharmacies, Group Purchasing Organizations, PBMs, and other segments and channels as required. This position will work closely with the Senior Director, Contract Operations and cross-functional leaders to ensure agreements meet business, legal, operational and compliance needs across several therapeutic areas. The ideal candidate will be familiar with and highly conversant in various segments of market access, discuss and incorporate contracting strategies...

The Director, Congress, Ad Board, and Strategic Council Lead, US Kidney is responsible for setting the strategic direction, planning, and flawless execution of congresses, advisory boards, and strategic councils for povetacicept and inaxaplin to support our launches in IgA nephropathy (IgAN) and APOL1-mediated kidney disease (AMKD). This leader will define and oversee the immediate and long-term vision for the company’s presence and influence across 50 regional and national conferences, ensuring alignment with the overall brand strategy and business objectives. Additionally, this person will be responsible for engaging with Key Thought Leaders (KTLs) to plan and execute high-impact ad boards and...

We are seeking a visionary People Research Associate Director to lead the design and execution of high-impact research initiatives that shape workforce strategy and elevate organizational effectiveness. This role demands deep expertise in experimental methods, program evaluation, and storytelling with data. The People Research Associate Director will hold a PhD in a relevant field and bring a strong track record of translating complex research into actionable insights for senior leadership. Key Duties and Responsibilities Lead End-to-End Research Design Architect and execute research studies to evaluate the effectiveness of HR programs, policies, and interventions. Plan, design and conduct experiments to understand...

Vertex Pharmaceuticals, Inc. is seeking a highly skilled and proactive Principal Research Associate to join our Human Cell Core, contributing to the development and execution of advanced human cell models at scale. The ideal candidate is an expert experimentalist who excels in a fast paced , team-oriented environment and operates with a high level of scientific rigor and independence. This role involves maintaining and expanding primary human cells at scale, operating automation-enabled cell culture platforms and executing functional assays to support cell optimization and troubleshooting efforts. Success in this position requires exceptional reliability, attention to detail, adaptability, problem solving skills...

The Senior Quality Manager will be part of the Program Quality Team in Vertex’s North America Commercial Patient Support Program Center of Excellence (NAC PSP COE). The COE is a group of compassionate and determined individuals who provide operational support to our commercial Patient Support Programs (Cystic Fibrosis, Hematology, Diabetes and Kidney) in areas such as systems and technology, data and analytics, vendor management and program quality. Additionally, COE team members help design patient support offerings and policies for future Vertex Patient Support Programs (PSP). The Senior Quality Manager will play a meaningful role within the COE and contribute to...

The Clinical Pharmacology Director leads strategic, scientific and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the development of clinical pharmacology plans; assists in departmental management through program reviews and collaborative decision-making; supervises asset leads, provides career development; routinely co-leads cross-functional efforts and leads department initiatives. Key Duties and Responsibilities Responsible for the application of clinical quantitative pharmacology strategy to support the immunology portfolio. Guides metabolic, co-dosing and drug-drug interaction issues, collaborating closely with cross functional colleagues. Co-leads or serves on cross-functional committees and/or contributes...