Vertex Job Trends

Why Join Us? At Vertex, we are a transformative biotechnology company dedicated to creating new possibilities in medicine to improve lives. With five transformative medicines for cystic fibrosis, a pioneering gene therapy for sickle cell disease and transfusion-dependent β-thalassemia, and a first-in-class non-opioid therapy for moderate to severe acute pain, we are at the forefront of healthcare innovation. Our robust pipeline and commitment to investing billions in R&D over the past two decades reflect our mission to transform the treatment of serious diseases. As Director, Commercial Legal Senior Counsel – Genetic Kidney , you will play a pivotal role in...

The Associate Director, Health System Engagement & Congress Lead is responsible for developing the strategy and execution for all national Health System Congress promotional activities (sponsorships, booths, media, product theater, etc.), all commercial Health System speaker and peer education investment and programs (strategy, content, operations), and Health System KTL insight-seeking initiatives (strategic councils, advisory boards, KTL meetings) within the U.S. Commercial Pain Business Unit. Vertex recently launched JOURNAVX, an oral, non-opioid medication for the treatment of moderate-to-severe acute pain. Peer education is a highly important way to generate awareness, understanding and excitement across the nations largest and most complex Health...

The Analytical Science and Technology (AS&T) Principal Scientist, Separation Method Expert, will be responsible for providing scientific and technical expertise within and across functional areas for late-stage & commercial methods and vendor management. S/He will manage the method life cycle, including method remediation, validation, transfer, troubleshooting and investigations for OOT/OOS, along with data trending analysis. Additionally, the principal scientist will partner closely with all stakeholders, and with contract testing sites establishing partnerships to ensure compliance with cGMP and Quality Management systems for the global network to deliver our medicines to patients effectively. Key Duties and Responsibilities Lead analytical method remediation,...

Vertex is seeking an accomplished scientific communications leader to serve as Publications Science Director, Medical Affairs (Endocrinology). Following the Crinetics acquisition, this role will lead the global publications strategy, planning, development, and execution for Vertex’s rare endocrinology portfolio, including the commercialized acromegaly franchise and the pipeline program in congenital adrenal hyperplasia (CAH), with the flexibility to support future endocrinology indications as the portfolio evolves. Working closely with the Global Medical Lead (GML), the Science Director will translate scientific and medical priorities into an integrated publication strategy that communicates clinically meaningful evidence to healthcare professionals and the broader endocrine and rare...

The Patient Safety Medical Director will provide medical safety expertise for assigned products, pre- and post-approval. The role will optimize patient safety of Vertex products and maintenance of compliance with the Pharmacovigilance regulations of Regulatory Agencies around the globe through the effective and timely completion of Safety activities through the product life cycle. Key Duties and Responsibilities Provides medical safety expertise, state of the art pharmacovigilance, and safety risk management for assigned products (marketed or in development) Responsible for the safety assessment activities of assigned products under the supervision of a Global Patient Safety (GPS) Disease-area Safety Head Autonomously monitors...

The Field Communication Engagement Senior Manager develops and executes clear, comprehensive communication plans that inform, engage, and activate field teams and key stakeholders. This role supports the VP of Strategic Customer Engagement and field sales leaders by driving engagement, supporting pipeline launches, and strengthening collaboration across the kidney field team. Key Duties and Responsibilities Create high-impact communication and messaging to support kidney field business goals. Proactively identify opportunities for communication optimization through regular field rides, team observations, and performance analysis to enhance field efficiency and effectiveness. Work with cross-functional partners to identify, build, and maintain best internal channels to drive...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Sr. Manager, Marketing Automation, CDP & OneTrust leads day-to-day execution of marketing automation, customer data activation, and consent integration. The role translates business requirements into operational requirements, manages customer data activation, partners with DTE and production partners to implement, test, and optimize capabilities. Internally, the focus is requirements, coordination, alignment, prioritization, and vendor oversight, while DTE and partners handle build and configuration. The role also builds the documented processes and clean data that will support AI-driven automation. Key Duties and Responsibilities Partner with business stakeholders to understand their strategic goals, customer-engagement objectives, and evolving channel needs. Translate business requirements...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex is seeking experienced and talented commercial leaders to join our US Pain Business Unit to support our journey to bring forth new options for the treatment of pain. The Territory Account Manager will be responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to generate advocacy and drive sales growth for the US Pain Business Unit, which is preparing for potential commercialization of an investigational novel selective inhibitor of NaV1.8 in acute pain. We are looking for candidates with a strong track record of delivering exceptional results with patient focus, developing...

At Vertex, we're relentless in our pursuit of scientific innovation to create transformative medicines for people with serious diseases. Our Hematology organization supports patients living with transfusion-dependent beta thalassemia (TDT) and sickle cell disease (SCD) through an established gene therapy product. This team is focused on sustaining momentum, expanding impact, and delivering a consistent, high-quality experience for patients, caregivers, healthcare professionals, and treatment centers. With the support of a global biotech company and the opportunity to help shape the continued evolution of Hematology, this Senior Director of Hematology role will contribute directly to strong performance and delivering innovation for patients...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex’s Automation of Machinery and Processes (AMP) Team is seeking a high-impact leader to develop cutting-edge manufacturing solutions for its Cell & Genetic Therapies programs. This pivotal role is at the forefront of automating complex processes in one of the most dynamic and rapidly evolving fields in biotechnology. You will work with a passionate team of engineers, scientists, and innovators united by a shared mission to push the boundaries of what’s possible in Cell & Genetic Therapy. This critical position will lead an interdisciplinary engineering team in novel equipment & systems development, vendor selection, equipment qualification, technology transfer, and continuous...

Vertex is growing at a rapid pace with challenging and exciting opportunities for motivated professionals who are keen to contribute to the Vertex mission to invest in scientific innovation and create transformative medicines for people with serious diseases. Our finance function is integral to achieving our company’s strategic goals, providing critical insights and analysis in support of decision-making across the organization. By joining our function, you will become part of a fast-moving, forward-thinking team to support the ongoing growth of a leader in the biotechnology industry. The Finance Manager of Clinical Development is a key member of Vertex's Finance business...

The Associate Director, GMP Operational Quality Assurance is a Quality leader and advanced technical resource responsible for strategic and operational Quality oversight across multiple complex programs. This role leads day-to-day quality operations, supports the execution of new initiatives, and applies sound judgment to resolve complex quality and compliance issues. The role provides Quality oversight for drug substance disposition from development through process performance qualification, ensuring decisions align with patient safety, product quality, regulatory expectations, and business continuity. This role serves as a visible Quality partner to Product Quality Leads, MSAT, Regulatory Affairs, operational stakeholders, CDMOs, and suppliers. The successful candidate...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Financial Planning & Analysis Senior Manager General/ The Senior Manager, G&A Functions, is a key member of Vertex's Financial Planning & Analysis team, providing financial direction and strategic insight including identification of key value drivers and business KPIs, helping functions deliver their short-term and long-term goals and influencing strategy. This role will help drive our annual budget process and will partner closely with functional teams to drive the financial performance management process for responsible functions (objective setting, budget vs. actuals, etc.), including the monthly forecast process, with a focus on influencing business operations and decisions through an understanding of the...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Director, Clinical Quality & Development Operations (CQDO) Operational Excellence provides strategic leadership and operational oversight of Global Clinical Operations (GCO) Ancillary Supply Management, Phase 1 Center of Excellence Alliance, Safety Distribution as well as Training & Development programs. The Director drives the execution of departmental strategy, ensuring robust processes, inspection readiness, and compliance across all areas. In addition, the Director serves as a key liaison, that overall supports GCO, advancing business processes and systems to drive effectiveness, standardization, and productivity. Key Duties and Responsibilities Defines and executes the overarching vision and strategy for Operational Excellence ensuring alignment with GCO...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex is seeking a Principal Analyst, G&A Technology to support our Legal, OBIE , and Corporate Communications functions. In this role, you will partner closely with stakeholders to deliver technology solutions that strengthen operations, enhance the user experience, and support strategic priorities across corporate functions, with a particular focus on Legal, Compliance and Corporate Communication needs. The ideal candidate combines deep expertise in technology delivery, stakeholder engagement, and cross-functional leadership with a proven track record of partnering with Legal, Compliance, and Corporate Communications organizations in complex, highly regulated environments. This person will translate business needs into scalable technology solutions, lead...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Company Overview Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. Collaboration is central to how Vertexians work across offices and teams worldwide. The Digital Technology and Engineering organization delivers secure, reliable, and intuitive technology experiences that enable employees to connect, collaborate, and advance Vertex’s mission. Role Summary The Sr. AV Conference and Events Technologies Platforms Administrator is a client-facing technical leader responsible for delivering an exceptional global audio/visual, videoconferencing, live event, webcast, and collaboration experience for Vertexians working in hybrid and in-office environments. This role serves as the...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

The Pain Territory Business Manager (TBM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. The TBM reports into a Regional Field Leader and serves as a field representative for JOURNAVX within the community setting. The TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

Vertex’s Data, Technology and Engineering (DTE) organization is seeking a Director, AI Portfolio Management to join the Project Management and Strategic Operations (PMSO) team. PMSO is responsible for streamlining and simplifying the work of Vertex’s data and technology teams and supporting the successful deployment of new technologies across the global enterprise. This role reports to the Senior Director, Project Management and Strategic Operations and partners closely with the Chief Technology Officer (CTO) to oversee a portfolio of AI-driven initiatives supporting Vertex’s ambition of a tech-enabled workforce. The role requires leadership across portfolio planning, financial management, governance, and oversight of program,...

Vertex Pharmaceuticals is seeking to hire a Patient Educator Senior Manager - WEST to join our growing team. The ideal candidate will reside in one of these metropolitan areas Los Angeles or San Francisco metro areas. This is a field based role and candidates must currently reside in the Western Region of the United States. This Patient Educator will report to the Director, Patient Educators and is responsible for providing people living and affected by sickle cell disease (SCD) and beta thalassemia (BT) with education, tools, and resources that help them have meaningful discussions with their healthcare providers. This team...

The Manager, Manufacturing Operations manages a team and gives oversight to the day-to-day operations of the Drug Product Facility. The responsibilities include defining and directing activities for the DPF and DPF personnel while maintaining organizational balance across the group. The Manager will foster interdisciplinary communication and understanding within the group and with other departments. Key Duties and Responsibilities Responsible for day-to day operation of the Drug Product Facility and maintaining a cGMP environment Direct the activities of the group through managing of staff, prioritization and assignment of tasks Responsible for aligning with site leadership to provide departmental and technical leadership...

The Manager, Manufacturing Operations leads cell therapy manufacturing activities and ensures execution aligns with production schedules, operational plans, and business objectives. This role is responsible for defining and directing activities for cell therapy and cell therapy personnel while maintaining organizational balance across the group. This position is accountable for safe, compliant, and efficient cGMP operations, including equipment setup, assembly, operation, disassembly, and cleaning, while providing leadership to supervisors and manufacturing staff. The Manager will foster interdisciplinary communication and understanding within the group and across departments, maintain an audit-ready facility, and support the successful production of pharmaceutical drug products. Key Duties...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

DUTIES Provide functional and technical support for the Oracle E-Business Suite (EBS), working primarily with the Oracle Process Manufacturing (OPM) related modules and supporting business stakeholders in the Supply Chain Management and Materials Management business functions. Collaborate with business partners to identify and prioritize areas for opportunity, gathering and refining requirements, determining options for solution design. Collaborate with developers, support team, and other data, technology, and engineering partners to deliver innovative technology-driven projects, enhancements, and integrations. Maintain reliable, scalable, and compliant systems that meet business needs. Create, analyze, and validate detailed functional and technical specification documents and process flows to...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Trade and Distribution Data and Analytics Manager Job Profile Summary Vertex is a biotechnology company with commercialized medicines for Cystic Fibrosis, Sickle Cell Disease, Transfusion Depended Beta-thalassemia and Acute Pain. Vertex also has a robust pipeline with programs in Type 1 Diabetes and targeted kidney diseases in phase 3 clinical trials, as well as several programs in phase 2 development. This opportunity is unique in the breadth of disease areas in scope as well as the product modalities which span small molecule, gene therapy, cell therapy, subcutaneous injections, and mRNA therapy, each requiring unique and innovative access and distribution strategies....

The Manufacturing Process & Technical Quality Associate Director provides end-to-end l quality oversight for cell and gene therapy programs across clinical development, commercialization, product launch, and post-approval lifecycle management. The role is responsible for establishing product quality standards for both established and emerging technologies, ensuring alignment with regulatory expectations and industry best practices, and proactively identifying and mitigating product quality risks throughout the product lifecycle and end to end patient journey. This position partners closely with Manufacturing, Technical Operations, Regulatory Affairs, and Quality stakeholders to support program execution and governance, ensuring business, regulatory, quality, and operational objectives are achieved while...

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group in Boston, MA. The Health Economics & Outcomes Research Senior Director will lead strategies and execution of evidence generation that optimize the value proposition of Vertex’s inline and pipeline assets for the Hemoglobinopathies (Heme) Disease Area through each stage of development, including launch and post-launch phases. This position reports to Global HEOR Cell and Gene Therapy Lead. Key Responsibilities · Serves as the HEOR Heme Disease Area Lead · Develops the HEOR strategy for assets in the Heme Disease Area from...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

General/ The Director, Manufacturing Process & Technical Quality provides Quality leadership and end-to-end technical Quality oversight for assigned Cell & Genetic Therapies programs from development through commercialization and post-approval lifecycle management. The role is accountable for translating Quality strategy into compliant execution, establishing phase-appropriate product and process standards, identifying and mitigating Quality risks, and enabling operational and site readiness. Working across Development, Technical Operations, Manufacturing, Supply Chain, Regulatory, and external partners, the Director ensures alignment with the Vertex Quality Management System, global regulatory expectations, and business priorities. Key Duties & Responsibilities Strategic Quality Execution Translate program and CGT Quality...

The Senior Analyst is a member of Vertex's Financial Planning & Analysis team supporting a number of functions by providing financial analyses including identification of key value drivers and business key performance indicators (KPIs). Helps functions achieve their short- and long-term goals through proactive day-to-day decision support. The role ensures relevant functional activities are reflected in company budgets, forecasts, and long-range planning. The role will build analytics and models to aid functional management in decision-making. Key Duties and Responsibilities Conduct the financial performance management process for assigned functions (i.e., objective setting, tracking budget versus actuals, etc.), including the monthly forecast...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Sr. Director, ICX Data, Analytics & AI leads the intelligence engine behind Vertex’s integrated customer experience. This role is accountable for the data, analytics, models, decisioning, and AI agents that power precision engagement today and enable Vertex’s broader agentic capabilities over time. The role sets the strategic direction for ICX data and AI capabilities; oversees the intelligence layer across the customer experience; and partners with Digital Technology & Engineering/Data Science Solutions (DTE/DSS), Commercial, Legal, Medical, Regulatory, and external vendors to deliver compliant, scalable, and commercially impactful solutions. Key Duties and Responsibilities Set and execute the data, analytics, AI, and...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Senior Director, CMC Product Leader (T1D) will lead the Chemistry, Manufacturing, and Controls (CMC) functional team supporting cell therapy products within Biopharmaceutical Sciences - Cell & Gene Therapy. The role is accountable for developing and executing integrated CMC strategies across development, scale-up, technology transfer, validation, regulatory submission, and commercialization readiness. As the CMC representative on the Program Team, a sub-team of the Disease Strategy Team, the CMC Product Leader will partner across BiopharmSci CGT, Manufacturing, Quality, Regulatory, Clinical, Commercial, Finance, and other functions to align CMC plans with broader product objectives. The successful candidate will provide strategic and technical...

We are seeking an innovative physician-scientist to lead drug discovery and translational research within the Hemoglobinopathies Research Group. This role serves as the cross-functional Research Project Lead for in vivo gene editing therapies, with additional responsibilities across the Leiden Research portfolio and broader hematopoietic stem cell (HSC) biology initiatives. The primary focus is to advance in vivo gene editing programs from preclinical proof-of-concept through IND-enabling studies and into Phase 1/2 trials. This leader will bridge clinical expertise with translational science to shape disease strategy, direct preclinical and translational research, and define the path to first-in-human studies. The successful candidate will...

The Associate Director, Manufacturing Operations for Cell Therapy leads a team responsible for the execution of multi-product manufacturing operations. This role is accountable for the compliant production of cell therapy products and for the oversight, development, and training of the manufacturing team to ensure the efficient and effective delivery of therapies to patients. The role also cultivates and leverages cross-functional partnerships to identify and implement creative solutions to organizational opportunities and challenges. The Associate Director, Manufacturing Operations reports directly to the Senior Director, Manufacturing Operations and is a key member of the operational and manufacturing execution leadership team. This position...

Vertex is growing at a rapid pace with exciting opportunities for motivated professionals who want to contribute to our mission to invest in scientific innovation to create transformative medicines for people with serious diseases. Our Finance function plays a critical role in delivering on this mission by shaping strategy, enabling informed decision making, and providing deep business insight to support value creation across the enterprise. General The Senior Director of Commercial Finance is a senior leader within the US Commercial Finance organization and serves as the primary strategic business partner to the US Commercial Vice President and Business Unit...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Senior Manager, Manufacturing Operations manages a supervisory team and provides oversight to the day-to-day operations. This position provides strategic and operational leadership to ensure safe, compliant, and efficient execution of cGMP manufacturing operations in alignment with production schedules, site objectives, and business priorities. The Senior Manager is accountable for maintaining an audit-ready facility, driving continuous improvement, building organizational capability, and supporting the successful production of pharmaceutical drug products. Key Duties and Responsibilities Manage and develop a supervisory team, ensuring strong execution, accountability, and team effectiveness. Direct the activities of the group through management of staff, prioritization, and assignment of...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

We are seeking a highly motivated and experienced computational chemist to join our Computational Drug Design group in Boston. This individual will be responsible for contributing to both hit/lead identification and optimization programs using a broad range of computational approaches including molecular modeling, cheminformatics, data science, and AI-enabled methods. The right candidate's responsibilities include close interaction with interdisciplinary projects teams to identify and advance safe and efficacious molecules. In addition, this individual will work collaboratively within the global Data and Computational Sciences group to provide expertise in data analysis, computational chemistry and AI method development. This individual must demonstrate strong...

The Director, Integrated Customer Experience (ICX), Brand Engagement is responsible for translating brand priorities and customer needs into integrated healthcare professional (HCP) and patient experience strategies, prioritized journeys, activation roadmaps, and measurable business outcomes. This role is a strategic and trusted thought-partner to internal Business Units, working across Brand, Data and Technology, Insights and Analytics, Medical and external agency partners. The Director will define and orchestrate the customer experience vision and associated ICX activation plan, establish clear priorities across channels and touchpoints, enable consistent execution through enterprise standards and governance, and identify opportunities to apply AI and emerging digital capabilities...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Manufacturing Operations Supervisor is a critical first-line leadership role within Cell Manufacturing. This position is responsible for direct management of personnel executing GMP cell processing operations for adherent and suspension cell cultures. The candidate will have strong leadership skills, GMP expertise, and commitment to patients. The Supervisor will work one of the following shifts Second Shift - Tuesday to Saturday, 230PM - 11PM Second Shift - Sunday to Thursday, 230PM - 11PM Key Duties and Responsibilities Builds and develops an efficient team of 2-8 direct reports capable of consistently producing clinical cellular product or intermediates according to cGMP standards....

The Manufacturing Operations Supervisor is a critical first-line leadership role within Cell Manufacturing. This position is responsible for direct management of personnel executing GMP cell processing operations for adherent and suspension cell cultures. The candidate will have strong leadership skills, GMP expertise, and commitment to patients. The Supervisor will work one of the following shifts Second Shift - Tuesday to Saturday, 230PM - 11PM Second Shift - Sunday to Thursday, 230PM - 11PM Key Duties and Responsibilities Builds and develops an efficient team of 2-8 direct reports capable of consistently producing clinical cellular product or intermediates according to cGMP standards....

The Regional Field Leader, Associate Director will be responsible for the oversight of one of the eighteen geographic regions across three area teams for the US Pain Business Unit, which is preparing for potential commercialization of an investigational novel selective inhibitor of NaV1.8 in acute pain. We are looking for candidates with a strong track record of delivering exceptional results, establishing a strong team culture that aligns with Vertex values, and developing deep strategic account relationships. Regional Leaders will lead a team of 8-10 pain territory account managers and report into one of our three Area Field Leaders, Senior Directors....

The Principal Scientist Aseptic Control is recognized as having expertise in the principals and application of sterile and low bioburden processing technologies and providing technical support for manufacturing of cell and gene therapy (C>), small molecule, and combination medical device programs within cCMP manufacturing. This aseptic processing SME will partner with stakeholders to define strategies for microbial control of activities such as gowning, facility monitoring programs (EM, Water, Gases, etc.), disinfectant efficacy, aseptic processing simulations, filtration, particulate control, risk assessments, and will ensure the control strategies comply with industry guidance. The individual will interface with internal and external manufacturing sites...

The Senior Medical Science Liaison (Sr MSL) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights, and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources, and provide the...

The Senior Manager, Manufacturing Operations manages a supervisory team and provides oversight to the day-to-day operations. This position provides strategic and operational leadership to ensure safe, compliant, and efficient execution of cGMP manufacturing operations in alignment with production schedules, site objectives, and business priorities. The Senior Manager is accountable for maintaining an audit-ready facility, driving continuous improvement, building organizational capability, and supporting the successful production of pharmaceutical drug products. Key Duties and Responsibilities Manage and develop a supervisory team, ensuring strong execution, accountability, and team effectiveness. Direct the activities of the group through management of staff, prioritization, and assignment of...