Vertex Job Trends

Vertex is seeking a talented leader to join our US Pain Field Medical team to support our journey to bring transformative medicines to patients. The Medical Strategy and Operations Manager is a critical medical leader tasked with preparing plans and execute tactics required for optimal field medical team performance. This role entails collaborating with members and leaders of field-facing teams and internal stakeholders to maximize field medical opportunities while meeting assigned performance goals. This individual will focus on designing and supporting execution of field medical plans. The role involves close collaboration with medical home office strategy, Medical Operations, Medical Information,...

Vertex currently operates at the forefront of rare disease scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Pain, Type 1 diabetes, APOL-1 Mediated Kidney Disease, Duchenne Muscular Dystrophy, and Alpha-1 Antitrypsin Deficiency, among others. The Associate Director, Market Access Strategy will be responsible for delivering impactful market access strategies and resources to maximize access and uptake for...

Vertex is seeking a talented leader to join our US [Pain/Nephrology] Field Medical team to support our journey to bring transformative medicines to patients. The Medical Strategy and Operations Manager is a critical medical leader tasked with preparing plans and execute tactics required for optimal field medical team performance. This role entails collaborating with members and leaders of field-facing teams and internal stakeholders to maximize field medical opportunities while meeting assigned performance goals. This individual will focus on designing and supporting execution of field medical plans. The role involves close collaboration with medical home office strategy, Medical Operations, Medical Information,...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Candidate must reside in Fairfax, Alexandria, Washington, DC Proper, Arlington, Reston, McLean areas. The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital...

The Project Management Senior Manager will be responsible for the integration, creation and execution of multiple department projects. By partnering closely with departmental management and cross-functional Project Team members, the incumbent develops and maintains fully integrated project plans to ensure that deliverables are successfully executed, are in accordance with project objectives, and are within budget. The incumbent is also responsible for comprehensive communication, including status reporting, risk management and escalation of issues to cross-functional stakeholders and Senior Management. Key Duties and Responsibilities Leads multiple departmental projects Develops plans, goals, and logistics for projects, gaining cooperation and alignment Works closely with...

The Clinical Scientist Principal will provide scientific, clinical, and operational input to early and late stage clinical development programs with an emphasis on protocol-specific, in-life clinical data monitoring activities. This role will work on cross-functional study teams on design, execution, and monitoring of clinical trials, as well as data interpretation and communication. This role will also serve as a point of contact for investigators in day-to-day clinical study needs. Key Duties and Responsibilities Works with cross-functional team with oversight by the Medical Lead to conduct clinical studies, including clinical and safety data review, site interface on clinical study content, preparation...

The Clinical Pharmacologist Associate Director manages scientific and operational aspects at a study level and assists development at a program level. He/she may represent the department on cross-functional study teams and contribute toward clinical pharmacology plans. The candidate will have expertise in clinical pharmacology concepts and applications. He/She will have the ability to effectively communicate, both in verbal and written form. Key Duties and Responsibilities Representation for clinical pharmacology at a program level and oversee all study-related activities Contribute to clinical pharmacology plans including drug-drug interaction, special population and safety studies Generate hypothesis and provide strategy for clinical pharmacology study...

The Clinical Budget Management Director oversees the Clinical Budget Analyst team in Global Clinical Operations. This role leads the group responsible for broader financial understanding or insight into defined clinical projects and will have direct responsibility for the financial health of clinical studies. This role liaises between Clinical Operations, Outsourcing and Finance, providing oversight support for invoicing and overall study budgets, and provides valuable analysis and metrics to help improve the financial management of clinical studies. Key Duties and Responsibilities Overall management, onboarding and training of the Clinical Budget Analysts Mentor and train junior staff and provide training opportunities for...

At Vertex Pharmaceuticals, we are relentless in our pursuit of transforming the lives of people with serious diseases. We are seeking a highly motivated and enthusiastic Research Scientist to join our Structural Biology and Biophysics team in Boston. This is an exciting opportunity to be part of a collaborative team dedicated to producing and characterizing high-quality recombinant proteins for structural, biochemical, and biophysical studies. Your contributions will play a critical role in elucidating target mechanisms of action and ligand engagement, driving our mission to deliver transformative therapies to patients. As a Research Scientist, you will work in a dynamic, fast-paced...

The candidate must reside in Harrisburg East or Philadelphia Suburbs West. The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting...

The Clinical Scientist Principal will provide scientific, clinical, and operational input to early and late stage clinical development programs with an emphasis on protocol-specific, in-life clinical data monitoring activities. This role will work on cross-functional study teams on design, execution, and monitoring of clinical trials, as well as data interpretation and communication. This role will also serve as a point of contact for investigators in day-to-day clinical study needs. Key Duties and Responsibilities Works with cross-functional team with oversight by the Medical Lead to conduct clinical studies, including clinical and safety data review, site interface on clinical study content, preparation...

Vertex is seeking an experienced commercial leader to implement field sales and non-personal promotion tactics in support of the North America Commercial (NAC) business. The Customer Strategy & Execution Lead (CSEL) will partner with North America commercial organization to implement the go-to-market (GTM) strategy and deliver customer solutions that meet the business needs. This role will work directly with the BU stakeholders, Field Operations Leads, Digital Operations Leads, Customer Data Management, and technical stakeholders to optimize HCP customer experience. This role will have direct responsibility in supporting one of the dedicated BU teams, and will report to the Director, Customer...

As the Sample Operations Program Management, Associate Director , you will be responsible for overseeing the portfolio of projects across the Vertex Sampling and In Hospital Pilot Programs and aligning them with strategic department goals to ensure successful, efficient delivery. This role is responsible for ensuring robust and balanced cross-functional planning, implementation, monitoring, and reporting of the Sample Operations program enhancements and operational execution. This individual will define roadmaps and mitigate risks across multiple interconnected initiatives, including the management of project plans, system/operational enhancements, process documentation, and analytical insights to advance the business strategy and customer experience. This role will...

The Senior Administrative Assistant provides experienced office/business support to a department. The Senior Administrative Assistant generally reports directly to a(n) Country Manager, Executive Director or Vice President-level manager. Key Duties and Responsibilities Manages calendars for assigned personnel, including meeting scheduling (both internal and off-site meetings), accepting/declining invites, meeting prioritization, securing conference rooms, ordering catering and "day-of" logistical and administrative support Serves as a departmental resource for Vertex's internal technologies (i.e; Procurement, SharePoint, Concur, Vertex U, VLearn, etc.) Exchanges and integrates information from stakeholders into departmental reports Books flights/hotels, completes expense reports, and arranges team lunches/dinners and offsite meetings for assigned...

The Principal Scientist, Stem Cell Research provides scientific leadership and ownership of stem cell differentiation, characterization, and assay strategies supporting Vertex stem cell therapy programs. This is a hands‑on, lab‑based role with responsibility for defining experimental direction, setting scientific standards, and driving decision‑making for complex stem cell-derived cellular platforms. The Principal Scientist serves as a subject‑matter expert and scientific authority, guiding strategy, assessing risk, and integrating biological, technical, and data‑driven evidence to advance robust differentiation and characterization approaches toward preclinical and IND‑enabling objectives. This role directly influences program strategy and milestones through independent scientific judgment and cross‑functional collaboration. Key Duties...

Job Summary Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. The role is as a Director within the Modeling Center of Excellence (CoE), a designated group within the HEOR team that provides strategic and technical modeling support to HEOR, Market Access & Pricing, and the broader commercial organization. The main responsibility of the Director will be to lead the team that supports the HEOR disease/asset teams in developing health economic models, including models that will...

The Pain Territory Business Manager (TBM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. The TBM reports into a Regional Field Leader and serves as a field representative for JOURNAVX within the community setting. The TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as...

Through internal audits the Internal Audit Manager will identify risk areas, evaluate business process controls and complete test plans on operational audits. Additionally, this role will provide recommendations to improve the effectiveness and efficiency of operations and business systems. This role will also participate in ensuring that the yearly internal control review is brought to fruition by interacting with SOX testers, other stakeholders, and subject matter experts on special projects and the development and execution of departmental goals. Key Duties and Responsibilities Plans and performs financial, operational and, as applicable, IT audits; reviews related records for compliance with established and...

The Senior Manager, Content Operations owns the day-to-day execution of our content transformation strategy and roadmap. The right candidate will sit at the intersection of strategy, execution, agencies, brand teams, and Data and Technology Engineering (DTE), enabling content excellence. You won’t just keep things running. You’ll play a major role in transforming how content gets planned, produced, governed, and delivered to our customers. Key Duties and Responsibilities Carry out the content transformation roadmap across marketing teams, agencies, MLR, and marketing operations Serve as the primary partner to DTE on content platforms, including requirements definition, prioritization, and delivery of enhancements Onboard...

This role owns how content is organized, governed, and made reusable at speed and scale. As the Content Operations Librarian, the ideal candidate will be responsible for ensuring content is structured, tagged, governed, and easy to find and reuse. You’ll help turn our core content from a collection of files into a strategic, reusable assets. Key Duties and Responsibilities Own content organization, taxonomy, metadata, and naming standards across platforms Ensure content is consistently tagged and structured to support reuse and reporting Partner with production and agency teams to enforce content standards at the point of creation Maintain and evolve content...

As the Sample Operations, Manager, you will act as the day-to-day lead for the Vertex Drug Sample Programs, overseeing operational activities for the direct-to-practitioner sample programs. This position will serve as the key escalation point for field-based employees for all matters related to sampling activities where you will assist, guide and enforce Vertex sampling policies and compliance with the Prescription Drug Marketing Act (PDMA). This role is critical in ensuring sample programs are consistently run in an effective and compliant manner by working closely with third party vendors and internal partners to influence decisions in alignment with organizational goals. This...

Role Summary We are seeking a Director to define and lead the enterprise GxP training strategy. This role sits at the intersection of business strategy, Quality governance, and operational enablement. The Director partners with senior leaders to understand business direction, clarify why training solutions are required, and translate regulatory and operational needs into a clear, prioritized roadmap with defined outcomes and accountability. In parallel, as QSO, the Director holds final authority for the system-level design, governance, compliance, and continuous improvement of the GxP Training Quality System within the Global QMS framework. The Director ensures the system remains compliant, effective, scalable,...

Vertex Pharmaceuticals is seeking a highly motivated and innovative scientist to join our growing immunology research site in Seattle as the Director-Head of Immune Cell Profiling. This leadership role offers a unique opportunity to shape the future of immunology research by building and leading a cutting-edge Molecular Profiling team. The successful candidate will drive strategy, develop advanced research capabilities, and lead a team of scientists to uncover novel biological insights in order to identify, validate and prioritize therapeutic targets. In addition, they will develop and execute a strategy for reverse translation optimally enabling serial innovation for immunological indications in line...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex Pharmaceuticals is seeking a highly motivated and dynamic Principal Research Scientist to join our Dissolution Team within the Formulation Development Department. This role offers a unique opportunity for a driven individual to contribute to the advancement of our scientific capabilities while growing into a leader within the team. The ideal candidate will possess a strong scientific foundation, a passion for learning, and the ability to lead with a sense of urgency and purpose. As a key member of the Dissolution Team, this individual will play a pivotal role in supporting our drug development efforts, driving innovation, and fostering a...

Vertex is entering a new phase of data-driven innovation where trusted, observable, and governed data is foundational. The Associate Director, Data Quality Platform is a senior technology and product leader within the Data & Software Engineering organization, reporting to the Director, Data Governance. This role owns the enterprise Data Quality (DQ) platform strategy and execution, with an explicit mandate to build AI-first, scalable and embedded data quality capabilities across the enterprise. The role partners closely with data stewards, data product owners, date engineering, analytics, compliance, privacy and security to translate data quality policies and standards into automated, measurable, and continuously...

The Senior Administrative Assistant provides experienced business support to the Quality department, reporting directly to a Vice President. The role is responsible for core administrative duties including calendar management, budget planning, and partnering with other assistants to drive continuous improvement. A primary focus of this position is establishing and leveraging digital technologies and AI to enhance task execution and optimize departmental workflows. Key Duties and Responsibilities Ensures seamless execution of day-to-day activities including proactive calendar management, meeting prioritization, and logistical support. Serves as a departmental resource for internal technologies such as SharePoint, Procurement, and Concur. Books travel logistics and completes...

Vertex Pharmaceuticals is seeking a Patient Support Training & Development Associate Director to join the North America Commercial Field Training (NACFT) organization. T he Associate Director will report to the Director of US Patient Support Training and will focus on improving the proficiency and effectiveness of our US patient-facing teams across the Vertex product portfolio. Ability to work in hybrid capacity or on site required. Key Duties and Responsibilities Develop and execute onboarding training programs to ensure that the Patient Support teams are trained , certified experts in Vertex products and Patient Support processes and education Partner with Patient Support...

The GxP Operations Support Manager will be responsible for supporting training documentation and electronic systems related to manufacturing and quality control at the Vertex Manufacturing Center (VMC). This role will primarily be responsible for creating, managing and delivering training content. The role may also involve serving as the business owner for QC laboratory computerized systems batch record and analytical data review, quality event ownership, and support for systems such as MES, LIMS, Tulip, and electronic training platforms. Key Duties and Responsibilities Manage the overall GxP training process, including hosting training sessions, assigning training modules, and maintaining up-to-date training materials to...

The Supervisor, Facilities Operations role is responsible for critical GXP facilities operations and maintenance tasks and requirements. The Supervisor, Facilities Operations role supervises facilities technicians in addition to facilities contractors to ensure completion of work orders in the CMMS system. This role is also responsible for supervising the operations of all site utilities, mechanical, HVAC and electrical systems. Key Duties and Responsibilities Performs reactive and preventative facilities maintenance tasks and jobs generated from CMMS work order system. Oversees staff facilities technicians and external facilities contractors in the execution of site maintenance and repair activities. . Performs and completes small facilities...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Project Management Associate Director will operationally lead the integration, creation and execution of multiple complex departmental development plans within Medical Affairs as a member of the Medical Affairs Project Management team. Partnering closely with Project Leaders , Global Medical Leads (GMLs), Regional Medical Leads (RMLs), and cross-functional teams, the incumbent will ensure delivery of strategic and operational priorities across disease areas and geographies. This role requires a proactive, strategic thinker with strong judgment who can manage diverse needs, drive cross ‑ functional alignment, and ensure seamless execution of Medical Affairs objectives. Responsibilities span project planning, risk and governance management,...

The ideal candidate will be located in the general White Plains area or Westchester and surrounding areas. The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select...

About Vertex Vertex is at the forefront of innovation, leveraging cutting-edge technology to deliver transformative solutions that drive business success. We are seeking a visionary and experienced AI Platform Owner with experience leading large complex initiatives and teams to own the development and deployment of scalable Artificial Intelligence (AI) Authoring applications and platforms within our data and technology organization. This role offers a unique opportunity to shape the future of AI-driven content creation at Vertex and make a significant impact on our business and industry. As part of Vertex’s Data and Software Engineering team, this role will report to...

The Audit Management Associate Director is responsible for the audit and inspection management for assigned activities, inclusive of internal and external processes. This role has responsibility for design and execution of compliance audits primarily across GCP/GLP suppliers and clinical investigator sites through the development of a risk-based audit program designed to support activities across Vertex business functions. This role ensures adherence to applicable regulations, industry standards, and to Vertex policies, procedures, and quality standards as set forth in the Quality Management System. This role may be a generalist but more often specializes in laboratory or clinical practices. Regularly applies specialized...

Vertex is seeking a talented scientist to join our small molecules Analytical Development group in Boston, MA. This individual will play a central role in advancing transformative medicines by leading analytical chemistry activities for small molecule development programs from preclinical through to Phase 1. This role includes representing Analytical Development at cross-functional project team meetings and so demonstrable experience to resolve project challenges in collaboration with other R&D functions is required. The ability to work both independently and in a matrix team environment is essential to succeed in this position. Key Duties and Responsibilities Project oversight represent Analytical Development at...

The Associate Director/Director of Capability Solutions and Data Management will lead the development and management of data-driven capabilities to support market access strategies, payer engagement, reimbursement, contracting, and patient access outcomes. Reporting to the Senior Director of Market Access Analytics & Insights, this role focuses on building scalable data foundations, governance frameworks, and advanced analytics tools to drive impactful business results and improve patient outcomes. Key Responsibilities Develop and execute capability roadmaps for data management, analytics, and solutions aligned with U.S. and global Market Access priorities for in-line brands and pipeline assets. Oversee data enablement initiatives, creating analytics-ready data products...

Vertex is seeking a strategic and analytical leader to serve as Director, Market Access Analytics & Forecasting . This role will lead a high-performing team to deliver actionable insights from U.S. market access data, including formulary/coverage data (e.g., MMIT), claims/utilization data (e.g., IQVIA LAAD), gross-to-net (GTN) forecasting inputs, and trade/channel analytics. These insights will drive market access strategy, contracting decisions, and performance management. As a trusted advisor to cross-functional stakeholders, this leader will translate complex access and channel dynamics into clear, data-driven recommendations for senior leadership and field execution. The role will also focus on building durable analytic capabilities, ensuring...

The Supply Chain Standards, Reporting and Analytics (SRA) Manager leads the CDMO digital integration efforts for Supply Chain in partnership with Supply Chain teams, and the Data, Technology, and Engineering (DTE) organization. Additionally, this role will support the development of analytics, KPIs, reporting, and data standards for SCM across all disease areas and enable insights with effective data visualization. This person will collaborate closely with SCM and DTE stakeholders to understand needs and shape deliverables for analytics, KPIs and reporting. KEY RESPONSIBILITIES Lead CDMO digital integration work for supply chain. Ensure supply chain requirements are understood by the integration team...

The Clinical Development Associate Medical Director will serve as the Medical Lead for clinical trials, working with cross-functional teams on trial strategy, design, execution, and reporting. In addition to oversight and accountability for the study as a whole, this role will serve as the internal primary Medical Monitor accountable for monitoring the safety of enrolled subjects and ensuring scientific integrity. The incumbent may participate in other projects to support the clinical development program. Key Duties and Responsibilities Participates in the development of Study Protocols, Investigator's Brochures, Clinical Development Plans and other key documents in conjunction with other line functions and...

The successful candidate will be responsible for Manufacturing Science and Technology (MSAT) activities for cell therapy products in our Type 1 Diabetes (T1D) program as well as our gene therapy (Casgevy) program. The candidate will provide cross-functional leadership in technology development and transfer from Development to Clinical Manufacturing and Process Performance Qualification including internal operations and potentially various CDMOs. The candidate will also plan and implement continuous improvement initiatives for life-cycle management working in cross-functional environment. Responsibilities Lead triage, investigation, and change control implementation as a Manufacturing Science and Technology functional area assessor and identify improvements, implement changes, and monitor...

We are seeking a highly skilled and experienced Compliance Associate Director to support in leading and executing compliance audits and monitoring across our organization. The ideal candidate will ensure adherence to regulatory requirements, internal policies, and industry standards while identifying areas for improvement and mitigating risks. This role requires a strategic thinker with strong leadership skills, exceptional attention to detail, and the ability to collaborate across departments to maintain a culture of compliance and integrity. The Compliance Associate Director will support the OBIE Assurance program, interacting with business colleagues across all regional Commercial, Medical, Clinical, Research, Development, and support functions....

Vertex is seeking an Associate Director of Patient Support & Engagement Analytics to lead analytics initiatives that optimize patient services and programs, primarily supporting therapies for hemoglobinopathies such as sickle cell disease and beta thalassemia. This role will leverage data-driven insights, patient journey analytics, and predictive modeling to enhance patient engagement and improve operational efficiency across Vertex’s patient support ecosystem. The ideal candidate is a highly skilled individual contributor with a proven ability to translate complex concepts into clear, actionable insights for diverse stakeholders. They demonstrate exceptional attention to detail and accuracy in deliverables, while working independently and proactively engaging...

Vertex is seeking a talented individual to join our Process Development organization supporting our cell, gene and biologics pipeline. The primary focus of the Director is driving execution of Vertex’s cell, gene and biological therapy program objectives with internal and/or external manufacturing partners (CDMOs). The position will be responsible for successful technology transfer, process validation, and lifecycle management of manufacturing processes. The range of tech transfers may include new product introductions as well as site-to-site transfers. These responsibilities include partner technical assessment, tech transfer and process establishment, initial process oversight (e.g., virtual and as person-in-plant), and performance management. The successful...

General/ The Senior Director, Manufacturing Technical Sciences QA is accountable for end-to-end technical quality oversight of cell and genetic program throughout clinical development, commercialization, product launch and post approval lifecycle management activities. This includes quality oversight of new process and product development, establishing relevant quality standards, ensuring internal and cross-functional alignment with industry and regulatory expectations, and identifying quality risks and mitigations throughout the life cycle for the assigned programs. The role will lead a team of process and analytical QA personnel and closely partner with operational stakeholders to participate in Cell & Genetic therapies projects, quality oversight of technical...

Overview / Purpose As Vertex’s US portfolio and pipeline expand, the Executive Director, US Commercial Technology is the senior technology leader accountable for end ‑ to ‑ end technology partnership, delivery outcomes, and operational performance for US Commercial priorities across multiple business units and horizontal capabilities. This role serves as the single, accountable technology point of contact for the SVP, US Commercial leadership and represents DTE function across US commercialization planning, governance, and execution. The role leads a team of senior technology and AI leaders and orchestrates shared/platform teams to deliver measurable improvements in customer engagement, go ‑ to ‑...

The Associate Director, Global Revenue Technical Accounting will lead and oversee the company’s revenue recognition processes, ensuring compliance with US GAAP (ASC 606) and other relevant accounting standards. This role will involve managing complex revenue transactions, ownership of the accounting policies and training curriculum, and leading the collaboration with cross-functional teams to support revenue related financial reporting requirements. The Associate Director will also play a critical role in audits, SEC filings, and the development of training tools for the revenue accounting team. Key Duties and Responsibilities Oversee the process for evaluating and documenting the revenue recognition (ASC 606) for customer...

The Director, Source-to-Contract Technology will define the technology strategy and lead a team responsible for the vision, roadmap, implementation, and support of Source-to-Contract technology solutions and related AI capabilities, including the Third-Party Risk Management (TPRM) platform (ProcessUnity), eSignature platform (DocuSign), and Contract Lifecycle Management (CLM) platform (Icertis). This position will collaborate with senior leaders and key stakeholders across several functional areas to identify, prioritize, and deliver technology solutions in support of their goals and objectives. Key Duties and Responsibilities Become a trusted partner by understanding the business needs and vision to deliver technology and related AI solutions to support and...

Vertex is seeking an experienced, innovative, passionate and inspirational senior scientific leader to join our research organization as the Seattle Research Site Head (Immunology).The successful candidate will be a well-recognized leader in immunology research and will have the ability to drive execution of high impact, high visibility projects thereby transforming our ability to reach more patients with a growing pipeline of lifechanging medicines. This is an essential hire for the company. Reporting to the SVP, Boston Research, this individual will be a critical leader in advancing the company’s research pipeline across biologic, immunology and autoimmune therapies. The successful candidate will...

The Associate Director, US Patient Marketing, will play a critical role in developing and executing patient-focused marketing tactics & strategies to support CASGEVY® (exagamglogene autotemcel). This individual will lead efforts to engage and empower patients and caregivers, ensuring that our marketing initiatives align with the needs of the patient community and drive awareness and education across branded and unbranded activities. The ideal candidate will have a strong background in marketing, a deep understanding of the US healthcare landscape, and a passion for making a difference in the lives of patients. Key Duties and Responsibilities Partner with patient advocacy groups, healthcare...

The Regulatory Strategy Senior Director is a regulatory leader with expert technical and tactical experience in regulatory strategy for the assigned global or regional position and will be responsible for overseeing the development and implementation of advanced global regulatory strategies for development programs (1) in emerging disease areas, (2) for additional development of registered Vertex medicines, and/or (3) for the support of Vertex marketed products. This incumbent will play a major role in shaping cohesive regulatory strategy across the assigned programs and ensuring effective integration of broad regulatory ideas/tactics supporting franchise strategy. This roles responsibilities may be global, regional or...

The Business Engagement & Technology Principal Analyst for Tax Systems will partner with business leadership in the Corporate Tax group to develop capabilities and systems roadmaps that align to support business strategy. Additionally, the Business Engagement & Technology Principal Analyst for Tax Systems will ensure team members maintain reliable, scalable and compliant systems that easily meet business needs by efficient delivery and enhancements that provide opportunities for developing and implementing innovative solutions and integrations. Key Duties and Responsibilities Act as a subject matter expert and become a trusted partner of the business leaders within their remit (Corporate Tax) Understand their...

We’re seeking a strategic and hands-on HR Business Partner Senior Director to support our growing commercial organization during an exciting period of expansion and innovation. This role will serve as the HR leader for 1-2 Disease Area U.S. Business Units (BUs) and work in partnership with the BU Vice President and their leadership teams. This new role will support teams during a period of growth, new product launches, and the continued evolution of legacy brands. The HRBP will drive talent strategies that enable business success, foster a high-performance culture, and support organizational agility in a fast-paced environment. This individual will...

Vertex is seeking a Principal Scientist, Translational Immunology to join our Seattle-based Research & Development organization. This role will provide scientific leadership at the interface of discovery and early development, translating immune disease mechanisms into robust, clinically actionable programs. The successful candidate will partner closely with Immune Cell Profiling, Discovery Immunology, Computational Sciences, Biomarkers, and Clinical colleagues to design and execute translational strategies that advance programs from late discovery through IND-enabling stages. This position requires deep immunology expertise, strong cross-functional leadership, and a proven ability to drive programs forward through data-driven decision-making. Key Duties and Responsibilities Provide translational immunology leadership...