Vertex Job Trends

Vertex Pharmaceuticals Incorporated Position Description Position Trade Account Associate Director Department Market Access, Trade & Distribution Reports To Senior Director, National Trade & Distribution Accounts Location Field-Based The Trade Account Associate Director (TAAD) is responsible for leading strategic account management and executing Vertex’s U.S. trade and distribution strategy across assigned channel partners. This role leads the negotiation, implementation, and ongoing management of Specialty Pharmacy and Retail Master Purchase and Service Agreements, Enhanced Service Agreements, and Distribution Purchase and Service Agreements. The TAAD plays a critical role in ensuring the effective distribution and availability of Vertex’s commercialized products and supporting...

Job Summary Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society. The Associate Director role is within HEOR’s Epidemiology Center of Excellence (CoE), a specialized team that develops patient population forecasts used to inform commercial opportunity and forecasting, clinical trial planning, long-range planning, regulatory filings, and external communications. In this role, the Associate Director will be responsible for supporting drug development programs in Vertex’s pipeline through the execution of strategic plans to obtain scientifically rigorous global...

The Executive Director, Global Commercial Analytics- Decision Science will lead the global Decision Science capability within Global Commercial Strategy. Reporting to the Vice President, Global Commercial Analytics, this leader will build an integrated team that frames priority business decisions, translates them into analytical questions, and applies advanced analytics to inform pipeline development and to improve commercial, launch, and portfolio choices. The Executive Director will establish common standards, methodologies, and scalable capabilities across segmentation, targeting, patient finding, resource allocation, scenario modeling, experimentation, and measurement. Working through disease-aligned Decision Science leads, this role will ensure analytics are embedded in decision-making and translated...

The Executive Director, Marketing / Head of Marketing, Endocrinology is responsible for defining and leading Vertex’s endocrinology marketing strategy across multiple assets. This role develops a deep understanding of the treatment landscape, customer and patient needs, and Vertex’s position in the market; sets strategic and performance goals; and leads execution across the portfolio. As a people manager, the Executive Director is accountable for the marketing budget and for building, developing, and leading a high-performing team. Key Duties and Responsibilities Define the endocrinology marketing strategy and oversee brand planning, launch readiness, and lifecycle activities, as applicable. Lead the development and execution...

The Health Economics & Outcomes Research Associate Director will participate in leading the development and execution of Health economics and outcomes research studies in support of Vertex's products. Key Duties and Responsibilities Leads others to execute complex HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value Gathers and synthesizes insights from Payers, KOLs and HEOR experts; stays current with scientific and policy trends and best practices and applies strategic and content expertise...

The Executive Director, Global Commercial Strategy (GCS) Kidney - Pove will be the senior commercial leader for povetacicept across the kidney indications, including immunoglobulin A nephropathy (IgAN) and primary membranous nephropathy (pMN). The role will own the global commercial strategy for the kidney franchise, supporting the near-term U.S. launch and subsequent global launches in IgAN while advancing pMN toward commercialization. The Executive Director will co-lead the povetacicept Kidney Program Team with the Development Lead, guiding program strategy and key development, lifecycle, and investment decisions. The role will lead global launch execution and lifecycle management in IgAN and build the global...

Vertex is seeking a talented Senior Research Associate to join a collaborative research team focused on Biologics conjugation and optimization in Boston, MA. The group’s mission is to deliver next generation biologics and genetic therapies impacting several therapeutic areas. We are looking for a candidate with a strong desire to support the development of targeted lipid nanoparticle (tLNP). In this lab-based role , ideal candidate will execute and improve laboratory workflows for lipid nanoparticle (LNP) conjugation and purification. The candidate should be independent, accustomed to taking initiative, and bring enthusiasm and intellectual curiosity to Vertex’s fast-paced research environment. Key Duties...

The Executive Director, Global Commercial Analytics- Market Research will lead the global Market Research capability within Global Commercial Strategy. Reporting to the Vice President, Global Commercial Analytics, this leader will build a team of market research experts who generate deep, objective insight into patients, healthcare professionals, caregivers, markets, and other stakeholders to inform development, commercialization, launch, and lifecycle decisions. This role requires both strategic leadership and deep research craft. The Executive Director will establish an operating model in which the internal team is intimately involved in the work framing business questions, selecting methodologies, conducting qualitative research, designing quantitative instruments, interpreting...

Job Summary Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society. The Associate Director role is within HEOR’s Epidemiology Center of Excellence (CoE), a specialized team that develops patient population forecasts used to inform commercial opportunity and forecasting, clinical trial planning, long-range planning, regulatory filings, and external communications. In this role, the Associate Director will be responsible for supporting drug development programs in Vertex’s pipeline through the execution of strategic plans to obtain scientifically rigorous global...

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. As Vertex continues to grow, we are accelerating capabilities in technology and data to remain at the forefront of science, medicine, and technology. The Data & Technology Engineering, Biopharmaceutical Science, Manufacturing, Supply & Quality organization is focused on improving patients’ lives through AI, data, and technology innovation. The Senior Director, Quality AI, Data & Technology Engineering will define and execute the strategic vision for transforming Vertex’s global Quality operations through AI, data, and technology. This leader will champion AI-driven approaches...

We are seeking an innovative physician-scientist to help lead translational research and product strategy within the Type 1 Diabetes Research Group. This role serves as a cross-functional research leader for SC-islet therapies, with additional responsibilities across the broader T1D research portfolio. The primary focus is to advance next-generation SC-islet therapies from discovery through translational development by integrating disease biology, stem cell biology, bioengineering, manufacturing, and clinical considerations. This leader will bridge clinical expertise with translational science, help direct preclinical and translational research, and guide the path toward future clinical development. The successful candidate will bring deep expertise in diabetes and...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Associate Director (AD) of Portfolio and Program Management (PPM) sits within the COO’s organization at Vertex and leads programs from Research through early Development. This role will support program teams involved in early research through to candidate preclinical development. The AD will partner with program leads and cross-functional teams to establish cross-functional strategy and plans to ensure execution against program goals. Key Duties and Responsibilities Support disease strategy development within Research and drive cross-functional decision-making across the drug research and early development lifecycle, ensuring alignment between scientific objectives, portfolio priorities, and organizational goals In partnership with the program leader...

The Clinical Development Medical Director will serve as the Medical Lead for Vertex clinical trials, working with cross-functional multidisciplinary study teams on clinical trial strategy, design and execution and serving as the Medical Monitor responsible for monitoring the safety of enrolled subjects on assigned trials. The incumbent will work on multiple trials in all Phases of clinical development, and may also participate in other selected projects in clinical development. Key Duties and Responsibilities Leads the development of Study Protocols, Investigator Brochures, Clinical Development Plans and other key study documents in conjunction with other line functions and with minimal guidance Functions...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Job Posting Senior Category Manager - Commercial Summary The Senior Category Manager will own Category Management activities across Vertex for certain Commercial/Marketing categories. Working collaboratively with internal business stakeholders, this role is expected to develop sound category and sourcing strategies for multi-year, multi-geography teams across regions. Duties will include development and execution of Sourcing Strategies, as well as RFx development, competitive bid analysis, contract development, negotiation planning, and strategic supplier management. The Senior Manager will interface closely with Business Partners to understand their business priorities and needs, and in turn, to define specific initiatives to support the business. This...

The GMP Operational Quality Senior Specialist supports the principles and application of quality assurance and regulatory compliance. The incumbent supports or executes a wide range of straightforward activities, and supports new/existing project initiatives. Key Duties and Responsibilities Supports quality oversight for root-cause analysis and product impact assessment for investigations as a result of deviations, OOS, and OOT investigations ensuring appropriate CAPA actions are identified. Supports change control assessments, implementation and closure Identifies and facilitates continuous improvement efforts Supports drafting and revising Quality Agreements between CMOs/Suppliers and Vertex, as needed Helps represents Vertex Quality on cross-functional working teams, applying strong communication...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Executive Assistant provides specialized, independent administrative/business support to a Senior Vice President. Key Duties and Responsibilities Serves as the primary support professional for a Sr. Vice President, independently handling a full range administrative activities As the delegate for the executive, handles details of a highly confidential and critical nature related to the function/department Interacts regularly with senior leaders inside and outside the Company in coordinating the affairs of the executive Manages the executive's complex and detailed calendar, frequently coordinating logistics and sharing information with other assistants and leaders both internally and externally; coordinates complex travel and meetings logistics, anticipating...

Role Summary Vertex is entering an exciting phase of commercial diversification. As we expand into new pipeline disease areas and new geographies, we are investing in data, technology, and AI to scale commercial operations globally. The Commercial, Medical and External Affairs Technology team is expanding our capabilities with increased investment in data, platforms, and AI. The Commercial AI Product Management team leads a portfolio of high-value AI products that help accelerate commercialization, improve decision-making, simplify operations, and strengthen customer and patient engagement. The team connects business priorities with responsible AI capability development, product delivery, adoption, and value realization across Commercial,...

The Formulation Senior Research Associate will perform an array of activities working with other scientists to advance drug candidates from exploratory development through commercial line extension in a Quality by Design (QbD) environment using lab based and computational tools. Key Duties and Responsibilities Contribute to the development of solid dosage forms for clinical and commercial use, generate data for project progression and regulatory filings, conduct a range of activities for optimization and scale up studies Help execute, and interpret laboratory experiments, with minimal supervision, to meet established project timelines Maintain accurate and complete laboratory notebook capturing protocols, results and observations...

Vertex Pharmaceuticals is a global biotechnology leader committed to scientific innovation and the development of transformative medicines for people with serious diseases. Our finance function is a strategic enabler of Vertex's mission — providing the insights, rigor, and partnership that drive high-quality decisions across the enterprise. This is a high-visibility, high-impact role at the frontier of science and finance — where your work directly shapes how Vertex invests in advancing its pipeline from target identification through candidate nomination and beyond. We are seeking a strategic finance leader to serve as Director, R&D Finance, acting as the primary finance partner to...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Senior Director, Portfolio & Program Management is a global role within the Program and Portfolio Management (PPM) organization. The incumbent is responsible for championing cross-functional project management excellence to programs across the drug development lifecycle (Research, Pre-clinical and Clinical Development, Registration and Commercialization). The incumbent is expected to lead the application of project management to identify opportunities, shape objectives and drive execution of global strategy for cross-functional drug development teams and portfolio operations initiatives. This role is a key leadership position within PPM, with accountability for the performance and end results of a department/area. Key Duties and Responsibilities Provide...

The Pain Territory Business Manager (TBM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. The TBM reports into a Regional Field Leader and serves as a field representative for JOURNAVX within the community setting. The TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as...

The Senior Manager, Heme Patient Support Communications team member will be part of the Heme Patient Support Team within the Vertex Patient Support Business Unit. The Heme Patient Support Team is dedicated to providing end-to-end order management support for Authorized Treatment Centers (ATCs) and support for patients undergoing gene therapy for sickle cell disease (SCD) and transfusion dependent thalassemia (TDT). This individual will be become deeply familiar with the CASGEVY treatment journey and needs of key HCP & patient communities. Key Duties and Responsibilities Clearly understand and compliantly support the needs of healthcare providers and patients undergoing treatment with CASGEVY...

The Director of Portfolio and Program Management (PPM) sits within the COO organization and provides strategic and operational leadership across a portfolio of cross-functional Research programs and projects, spanning early research through candidate preclinical development. The role is accountable for both portfolio-level oversight and direct program management, ensuring alignment with research priorities and delivery against organizational objectives. Working in close partnership with the Cell and Gene Therapies (CGT) Site Head, Chief of Staff, Program Leaders, and cross-functional stakeholders, the Director provides integrated portfolio insights, enables prioritization, drives strategic decision-making, and ensures execution of critical site and program objectives. As a...

The Pain Territory Business Manager (TBM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. The TBM reports into a Regional Field Leader and serves as a field representative for JOURNAVX within the community setting. The TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex is seeking a talented individual to join our Process Development team as a Senior Scientist. The primary focus of this role is to lead the execution of process development and engineering studies for a cell-based drug candidate designed to treat diabetes. The Senior Scientist will be responsible for internal process development work, including process robustness and characterization studies, and may support manufacturing investigations. Importantly, the Senior Scientist will lead a weekend shift team to provide continuity for on-going studies over weekends and holidays. Shift Information This is a full-time weekend Thursday to Monday 8am to 5pm. The Process Development...

Vertex is seeking an experienced and talented commercial leader to join the US Pain Business Unit. The Area Director, Strategic Accounts will be responsible for leading the Strategic Accounts Team that supports the largest health systems in the Western US, with the adoption of Journavx, an oral non-opioid, inhibitor of NaV1.8 in the treatment of acute pain. We are seeking candidates with a strong track record of exceptional results, establishing a culture of performance that aligns with Vertex values, while expanding deep relationships across target health systems. The Area Director, Strategic Accounts, will lead a team of Strategic Account Leaders...

The Principal Engineer, Microsoft 365 and Copilot Platforms serves as the execution-focused technical lead for Microsoft 365 Modern Work and enterprise AI capabilities. This role translates business demand into secure, governed, supportable outcomes. The ideal candidate provides technical leadership across Microsoft Teams, SharePoint Online, OneDrive, Exchange with deep specialization in Microsoft Copilot, GitHub Copilot, Copilot Studio, agents, and AI governance. The role balances approximately 60% hands on work with 40% technical leadership. Key Duties and Responsibilities Own Technical Delivery Lead Modern Work and AI initiatives, technical design, change control, implementation, working with our operations team. Lead business escalations, Critical incident...

The Pain Territory Business Manager (TBM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. The TBM reports into a Regional Field Leader and serves as a field representative for JOURNAVX within the community setting. The TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as...

Vertex completed its acquisition of Crinetics Pharmaceuticals on September 1, adding commercial and pipeline endocrinology programs to Vertex’s innovation portfolio. The acquisition is expected to accelerate revenue growth and enhance the Company’s long-term earnings profile. The acquired portfolio includes PALSONIFY® (paltusotine), atumelnant, and several additional pipeline programs. PALSONIFY is the first and only once-daily oral therapy for acromegaly; it has launched in the United States, is approved in the European Union, and is under review by other global regulatory authorities. Atumelnant is an investigational, once-daily oral adrenocorticotropic hormone (ACTH) receptor antagonist in Phase 3 development for congenital adrenal hyperplasia (CAH)...

Vertex completed its acquisition of Crinetics Pharmaceuticals on September 1, adding commercial and pipeline endocrinology programs to Vertex’s innovation portfolio. The acquisition is expected to accelerate revenue growth and enhance the Company’s long-term earnings profile. The acquired portfolio includes PALSONIFY® (paltusotine), atumelnant, and several additional pipeline programs. PALSONIFY is the first and only once-daily oral therapy for acromegaly; it has launched in the United States, is approved in the European Union, and is under review by other global regulatory authorities. Atumelnant is an investigational, once-daily oral adrenocorticotropic hormone (ACTH) receptor antagonist in Phase 3 development for congenital adrenal hyperplasia (CAH)...

The Pain Territory Business Manager (TBM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. The TBM reports into a Regional Field Leader and serves as a field representative for JOURNAVX within the community setting. The TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as...

The Clinical Development Associate Medical Director will serve as the Medical Lead for clinical trials, working with cross-functional teams on trial strategy, design, execution, and reporting. In addition to oversight and accountability for the study as a whole, this role will serve as the internal primary Medical Monitor accountable for monitoring the safety of enrolled subjects and ensuring scientific integrity. The incumbent may participate in other projects to support the clinical development program. Key Duties and Responsibilities Participates in the development of Study Protocols, Investigator's Brochures, Clinical Development Plans and other key documents in conjunction with other line functions and...

Vertex is seeking a seasoned commercial executive to serve as VP U.S. General Manager (GM), accountable for end-to-end business performance, including results delivery, performance management, budget and strategic priorities for their designated portfolio, in the US. The VP GM will lead a fully integrated U.S. Business Unit, with responsibility for commercial execution through cross-functional alignment to sustain market leadership while preparing for future innovation. Key Duties & Responsibilities Owns full P&L responsibility for the U.S. designated Business Unit, delivering against revenue, profitability, and long-range plan commitments Leads an established commercial organization with opportunities for future builds with direct reports across...