Vertex Job Trends

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Company Overview Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. Collaboration is central to how Vertexians work across offices and teams worldwide. The Digital Technology and Engineering organization delivers secure, reliable, and intuitive technology experiences that enable employees to connect, collaborate, and advance Vertex’s mission. Role Summary The Sr. AV Conference and Events Technologies Platforms Administrator is a client-facing technical leader responsible for delivering an exceptional global audio/visual, videoconferencing, live event, webcast, and collaboration experience for Vertexians working in hybrid and in-office environments. This role serves as the...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

The Pain Territory Business Manager (TBM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. The TBM reports into a Regional Field Leader and serves as a field representative for JOURNAVX within the community setting. The TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex’s Data, Technology and Engineering (DTE) organization is seeking a Director, AI Portfolio Management to join the Project Management and Strategic Operations (PMSO) team. PMSO is responsible for streamlining and simplifying the work of Vertex’s data and technology teams and supporting the successful deployment of new technologies across the global enterprise. This role reports to the Senior Director, Project Management and Strategic Operations and partners closely with the Chief Technology Officer (CTO) to oversee a portfolio of AI-driven initiatives supporting Vertex’s ambition of a tech-enabled workforce. The role requires leadership across portfolio planning, financial management, governance, and oversight of program,...

Vertex Pharmaceuticals is seeking to hire a Patient Educator Senior Manager - WEST to join our growing team. The ideal candidate will reside in one of these metropolitan areas Los Angeles or San Francisco metro areas. This is a field based role and candidates must currently reside in the Western Region of the United States. This Patient Educator will report to the Director, Patient Educators and is responsible for providing people living and affected by sickle cell disease (SCD) and beta thalassemia (BT) with education, tools, and resources that help them have meaningful discussions with their healthcare providers. This team...

The Manager, Manufacturing Operations manages a team and gives oversight to the day-to-day operations of the Drug Product Facility. The responsibilities include defining and directing activities for the DPF and DPF personnel while maintaining organizational balance across the group. The Manager will foster interdisciplinary communication and understanding within the group and with other departments. Key Duties and Responsibilities Responsible for day-to day operation of the Drug Product Facility and maintaining a cGMP environment Direct the activities of the group through managing of staff, prioritization and assignment of tasks Responsible for aligning with site leadership to provide departmental and technical leadership...

The Manager, Manufacturing Operations leads cell therapy manufacturing activities and ensures execution aligns with production schedules, operational plans, and business objectives. This role is responsible for defining and directing activities for cell therapy and cell therapy personnel while maintaining organizational balance across the group. This position is accountable for safe, compliant, and efficient cGMP operations, including equipment setup, assembly, operation, disassembly, and cleaning, while providing leadership to supervisors and manufacturing staff. The Manager will foster interdisciplinary communication and understanding within the group and across departments, maintain an audit-ready facility, and support the successful production of pharmaceutical drug products. Key Duties...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

DUTIES Provide functional and technical support for the Oracle E-Business Suite (EBS), working primarily with the Oracle Process Manufacturing (OPM) related modules and supporting business stakeholders in the Supply Chain Management and Materials Management business functions. Collaborate with business partners to identify and prioritize areas for opportunity, gathering and refining requirements, determining options for solution design. Collaborate with developers, support team, and other data, technology, and engineering partners to deliver innovative technology-driven projects, enhancements, and integrations. Maintain reliable, scalable, and compliant systems that meet business needs. Create, analyze, and validate detailed functional and technical specification documents and process flows to...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Trade and Distribution Data and Analytics Manager Job Profile Summary Vertex is a biotechnology company with commercialized medicines for Cystic Fibrosis, Sickle Cell Disease, Transfusion Depended Beta-thalassemia and Acute Pain. Vertex also has a robust pipeline with programs in Type 1 Diabetes and targeted kidney diseases in phase 3 clinical trials, as well as several programs in phase 2 development. This opportunity is unique in the breadth of disease areas in scope as well as the product modalities which span small molecule, gene therapy, cell therapy, subcutaneous injections, and mRNA therapy, each requiring unique and innovative access and distribution strategies....

The Manufacturing Process & Technical Quality Associate Director provides end-to-end l quality oversight for cell and gene therapy programs across clinical development, commercialization, product launch, and post-approval lifecycle management. The role is responsible for establishing product quality standards for both established and emerging technologies, ensuring alignment with regulatory expectations and industry best practices, and proactively identifying and mitigating product quality risks throughout the product lifecycle and end to end patient journey. This position partners closely with Manufacturing, Technical Operations, Regulatory Affairs, and Quality stakeholders to support program execution and governance, ensuring business, regulatory, quality, and operational objectives are achieved while...

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group in Boston, MA. The Health Economics & Outcomes Research Senior Director will lead strategies and execution of evidence generation that optimize the value proposition of Vertex’s inline and pipeline assets for the Hemoglobinopathies (Heme) Disease Area through each stage of development, including launch and post-launch phases. This position reports to Global HEOR Cell and Gene Therapy Lead. Key Responsibilities · Serves as the HEOR Heme Disease Area Lead · Develops the HEOR strategy for assets in the Heme Disease Area from...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

General/ The Director, Manufacturing Process & Technical Quality provides Quality leadership and end-to-end technical Quality oversight for assigned Cell & Genetic Therapies programs from development through commercialization and post-approval lifecycle management. The role is accountable for translating Quality strategy into compliant execution, establishing phase-appropriate product and process standards, identifying and mitigating Quality risks, and enabling operational and site readiness. Working across Development, Technical Operations, Manufacturing, Supply Chain, Regulatory, and external partners, the Director ensures alignment with the Vertex Quality Management System, global regulatory expectations, and business priorities. Key Duties & Responsibilities Strategic Quality Execution Translate program and CGT Quality...

The Senior Analyst is a member of Vertex's Financial Planning & Analysis team supporting a number of functions by providing financial analyses including identification of key value drivers and business key performance indicators (KPIs). Helps functions achieve their short- and long-term goals through proactive day-to-day decision support. The role ensures relevant functional activities are reflected in company budgets, forecasts, and long-range planning. The role will build analytics and models to aid functional management in decision-making. Key Duties and Responsibilities Conduct the financial performance management process for assigned functions (i.e., objective setting, tracking budget versus actuals, etc.), including the monthly forecast...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Sr. Director, ICX Data, Analytics & AI leads the intelligence engine behind Vertex’s integrated customer experience. This role is accountable for the data, analytics, models, decisioning, and AI agents that power precision engagement today and enable Vertex’s broader agentic capabilities over time. The role sets the strategic direction for ICX data and AI capabilities; oversees the intelligence layer across the customer experience; and partners with Digital Technology & Engineering/Data Science Solutions (DTE/DSS), Commercial, Legal, Medical, Regulatory, and external vendors to deliver compliant, scalable, and commercially impactful solutions. Key Duties and Responsibilities Set and execute the data, analytics, AI, and...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Senior Director, CMC Product Leader (T1D) will lead the Chemistry, Manufacturing, and Controls (CMC) functional team supporting cell therapy products within Biopharmaceutical Sciences - Cell & Gene Therapy. The role is accountable for developing and executing integrated CMC strategies across development, scale-up, technology transfer, validation, regulatory submission, and commercialization readiness. As the CMC representative on the Program Team, a sub-team of the Disease Strategy Team, the CMC Product Leader will partner across BiopharmSci CGT, Manufacturing, Quality, Regulatory, Clinical, Commercial, Finance, and other functions to align CMC plans with broader product objectives. The successful candidate will provide strategic and technical...

We are seeking an innovative physician-scientist to lead drug discovery and translational research within the Hemoglobinopathies Research Group. This role serves as the cross-functional Research Project Lead for in vivo gene editing therapies, with additional responsibilities across the Leiden Research portfolio and broader hematopoietic stem cell (HSC) biology initiatives. The primary focus is to advance in vivo gene editing programs from preclinical proof-of-concept through IND-enabling studies and into Phase 1/2 trials. This leader will bridge clinical expertise with translational science to shape disease strategy, direct preclinical and translational research, and define the path to first-in-human studies. The successful candidate will...

The Associate Director, Manufacturing Operations for Cell Therapy leads a team responsible for the execution of multi-product manufacturing operations. This role is accountable for the compliant production of cell therapy products and for the oversight, development, and training of the manufacturing team to ensure the efficient and effective delivery of therapies to patients. The role also cultivates and leverages cross-functional partnerships to identify and implement creative solutions to organizational opportunities and challenges. The Associate Director, Manufacturing Operations reports directly to the Senior Director, Manufacturing Operations and is a key member of the operational and manufacturing execution leadership team. This position...

Vertex is growing at a rapid pace with exciting opportunities for motivated professionals who want to contribute to our mission to invest in scientific innovation to create transformative medicines for people with serious diseases. Our Finance function plays a critical role in delivering on this mission by shaping strategy, enabling informed decision making, and providing deep business insight to support value creation across the enterprise. General The Senior Director of Commercial Finance is a senior leader within the US Commercial Finance organization and serves as the primary strategic business partner to the US Commercial Vice President and Business Unit...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Senior Manager, Manufacturing Operations manages a supervisory team and provides oversight to the day-to-day operations. This position provides strategic and operational leadership to ensure safe, compliant, and efficient execution of cGMP manufacturing operations in alignment with production schedules, site objectives, and business priorities. The Senior Manager is accountable for maintaining an audit-ready facility, driving continuous improvement, building organizational capability, and supporting the successful production of pharmaceutical drug products. Key Duties and Responsibilities Manage and develop a supervisory team, ensuring strong execution, accountability, and team effectiveness. Direct the activities of the group through management of staff, prioritization, and assignment of...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

We are seeking a highly motivated and experienced computational chemist to join our Computational Drug Design group in Boston. This individual will be responsible for contributing to both hit/lead identification and optimization programs using a broad range of computational approaches including molecular modeling, cheminformatics, data science, and AI-enabled methods. The right candidate's responsibilities include close interaction with interdisciplinary projects teams to identify and advance safe and efficacious molecules. In addition, this individual will work collaboratively within the global Data and Computational Sciences group to provide expertise in data analysis, computational chemistry and AI method development. This individual must demonstrate strong...

The Director, Integrated Customer Experience (ICX), Brand Engagement is responsible for translating brand priorities and customer needs into integrated healthcare professional (HCP) and patient experience strategies, prioritized journeys, activation roadmaps, and measurable business outcomes. This role is a strategic and trusted thought-partner to internal Business Units, working across Brand, Data and Technology, Insights and Analytics, Medical and external agency partners. The Director will define and orchestrate the customer experience vision and associated ICX activation plan, establish clear priorities across channels and touchpoints, enable consistent execution through enterprise standards and governance, and identify opportunities to apply AI and emerging digital capabilities...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Manufacturing Operations Supervisor is a critical first-line leadership role within Cell Manufacturing. This position is responsible for direct management of personnel executing GMP cell processing operations for adherent and suspension cell cultures. The candidate will have strong leadership skills, GMP expertise, and commitment to patients. The Supervisor will work one of the following shifts Second Shift - Tuesday to Saturday, 230PM - 11PM Second Shift - Sunday to Thursday, 230PM - 11PM Key Duties and Responsibilities Builds and develops an efficient team of 2-8 direct reports capable of consistently producing clinical cellular product or intermediates according to cGMP standards....

The Manufacturing Operations Supervisor is a critical first-line leadership role within Cell Manufacturing. This position is responsible for direct management of personnel executing GMP cell processing operations for adherent and suspension cell cultures. The candidate will have strong leadership skills, GMP expertise, and commitment to patients. The Supervisor will work one of the following shifts Second Shift - Tuesday to Saturday, 230PM - 11PM Second Shift - Sunday to Thursday, 230PM - 11PM Key Duties and Responsibilities Builds and develops an efficient team of 2-8 direct reports capable of consistently producing clinical cellular product or intermediates according to cGMP standards....

The Regional Field Leader, Associate Director will be responsible for the oversight of one of the eighteen geographic regions across three area teams for the US Pain Business Unit, which is preparing for potential commercialization of an investigational novel selective inhibitor of NaV1.8 in acute pain. We are looking for candidates with a strong track record of delivering exceptional results, establishing a strong team culture that aligns with Vertex values, and developing deep strategic account relationships. Regional Leaders will lead a team of 8-10 pain territory account managers and report into one of our three Area Field Leaders, Senior Directors....

The Principal Scientist Aseptic Control is recognized as having expertise in the principals and application of sterile and low bioburden processing technologies and providing technical support for manufacturing of cell and gene therapy (C>), small molecule, and combination medical device programs within cCMP manufacturing. This aseptic processing SME will partner with stakeholders to define strategies for microbial control of activities such as gowning, facility monitoring programs (EM, Water, Gases, etc.), disinfectant efficacy, aseptic processing simulations, filtration, particulate control, risk assessments, and will ensure the control strategies comply with industry guidance. The individual will interface with internal and external manufacturing sites...

The Senior Medical Science Liaison (Sr MSL) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights, and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources, and provide the...

The Senior Manager, Manufacturing Operations manages a supervisory team and provides oversight to the day-to-day operations. This position provides strategic and operational leadership to ensure safe, compliant, and efficient execution of cGMP manufacturing operations in alignment with production schedules, site objectives, and business priorities. The Senior Manager is accountable for maintaining an audit-ready facility, driving continuous improvement, building organizational capability, and supporting the successful production of pharmaceutical drug products. Key Duties and Responsibilities Manage and develop a supervisory team, ensuring strong execution, accountability, and team effectiveness. Direct the activities of the group through management of staff, prioritization, and assignment of...

At Vertex, we continue to invest in a future-ready workforce where AI helps people strengthen expertise, improve decision-making, and create greater impact for our people and patients. We are looking for an Associate Director, Workforce Intelligence to be the analytical and research engine behind how we plan our workforce, redesign work with AI, and make trusted workforce data easy for leaders to reach and act on. The role reports to the Senior Director of People Data, Analytics, & Technology and is fully dedicated to the Workforce Strategy & Innovation function, which spans workforce planning, Human-AI organizational design, and AI learning...

Role Summary Vertex is seeking a highly motivated Senior Research Scientist, Molecular & Cell Biology to join the Human Cell Models group in Boston Research. In this role, you will develop, characterize, and apply physiologically relevant human cellular models using stem cells and primary cells to deepen understanding of disease biology, identify therapeutic opportunities, and support the advancement of novel drug discovery programs. The successful candidate will bring deep expertise in disease modeling, with particular strength in neuronal model development using induced pluripotent stem cells (iPSC) and/or primary cells. This individual will have demonstrated experience developing neuronal models (i.e. dopaminergic...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Director will be responsible for building, maintaining, and continuously evolving Vertex’s Kidney forecasting capabilities across multiple assets and disease areas. This includes leading the development of robust forecast models, refining forecast logic and assumptions, and ensuring models remain responsive to new data, emerging insights, market events, and changes in program strategy. This leader will provide strategic forecasting and analytical support for key business questions, commercialization decisions, and portfolio planning needs. As a senior partner to Marketing, Commercial Strategy, Finance, Market Access, Medical, and other cross-functional stakeholders, the Director will bring objective perspective, strong business judgment, and deep forecasting expertise...

Role Summary The High Throughput Human Biology group is seeking a highly motivated Research Scientist to support discovery programs through the development and implementation of innovative human biology assays. Working in a collaborative, multidisciplinary environment, the successful candidate will draw on expertise in cellular and molecular biology, laboratory automation, and data analysis to develop in vitro assays spanning multiple levels of biological complexity and define their application within high-throughput screening strategies. The successful candidate will also evaluate and incorporate emerging technologies, establish scalable experimental workflows, and partner across disciplines to translate scientific needs into robust solutions. They will leverage AI-enabled...

GENERAL POSITION SUMMARY The Global Patient Safety (GPS) Pharmacovigilance Science (PVSci) Manager leads assigned activities related to cross-functional safety data monitoring, assessment, and aggregate reporting to regulatory agencies, and support signal and risk management activities. KEY RESPONSIBILITIES Leads PVSci activities for assigned Vertex product, including coordinating review of emerging safety data and ensuring timely identification and communication of any potential safety issues Prepares aggregate safety report content, including risk management plans and responses to regulatory authority requests Conducts signal detection/tracking and other assessments/risk management activities Provides project management support for PVSci deliverables by establishing and managing timelines, content planning and...

The Associate Director, Global Pain Forecasting & Analytics will join the Global Forecasting & Analytics team within the Commercial organization to lead forecasting and analytics for Vertex’s global Pain portfolio, spanning current programs and future pipeline assets. This role will serve as a key partner to the Global Pain Marketing Lead and Global Commercial Strategy, leading the development and evolution of forecast models that support long-range planning, near-term operations, commercialization decisions, and cross-functional alignment across Pain disease areas. The Associate Director will build, maintain, and continuously evolve Vertex’s global Pain forecasting capabilities. This includes developing a deep understanding of the...

The High Throughput Biology Senior Research Scientist is responsible for experimental productivity and emerging creativity and versatility. The Senior Research Scientist designs and executes experiments for major research projects. These may include the development of cells and prosecution of biochemical and cellular assays for small molecule hit finding campaigns. Demonstrates resourcefulness in running multiple activities concurrently, all related to achievement of goals/ objectives. Adapts to new projects rapidly and to multiple projects effectively ensuring alignment with corporate goals. The Senior Research Scientist commands a deep understand of specialized discipline(s) and possesses diverse project experience and a broad panorama of (relevant)...

This role will cover the territory of Grand Rapids, Michigan area, which includes Kalamazoo, Lansing, Muskegon, Holland, Wyoming, Battle Creek and Jackson. The preferred candidate will reside within the surrounding areas of this territory. The Kidney Territory Account Manager (KTAM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs), developing a strategic business plan, communicating thorough disease and product knowledge to HCPs and centers of care. This role must understand market dynamics in rare, complex disease states, demonstrate excellent judgment, and be motivated by the desire to improve patients' lives. The KTAM will report into a...

The Associate Director, Speaker Bureau Content & Execution, US Kidney will support development and execution of peer-to-peer educational content across the US Kidney franchise, with initial emphasis on AMKD. This role reports to the Director, Speaker Bureau and Content Lead, US Kidney and ensures the franchise has high-quality, strategically aligned content to support current and future educational initiatives. The Associate Director will initially focus on content development, agency coordination, review/approval support, and executional pull-through for AMKD, with support for IgAN and POVE as needed. Over time, the role may expand to include speaker training logistics, speaker readiness, field enablement, and...

The Senior Biostatistician II will perform scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with guidance and mentoring on new and complex issues. The incumbent will complete assigned work in a resourceful manner and create alternative approaches to achieve desired results. The incumbent will develop a good knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. Key Duties and Responsibilities Within assigned area, designs, develops and executes the technical/statistical infrastructure for the conduct and evaluation of clinical trials, observational studies, or real world data (RWD) investigations, including related areas/activities. Participates...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Role Summary The Automation Engineer supports management and implementation of control systems for equipment in a GMP manufacturing facility. This role supports equipment upgrades, troubleshooting, lifecycle planning, and compliant system operation as well as configuration for network integration and data historian management. The engineer provides day-to-day technical direction to contractors and works closely with Manufacturing, Engineering, Quality, Validation, and vendors. Key Responsibilities Support automation upgrades and modifications for data integrity and reliability improvements for manufacturing equipment. Configure, troubleshoot, test, and maintain PLCs, HMIs, industrial networks, and related automation components. Maintain OT asset inventories, software versions, patching records, and equipment lifecycle...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The GxP Operations Support Specialist will support the implementation, maintenance, and continuous improvement of digital manufacturing systems. Working under the guidance of more senior team members, this role will partner with Manufacturing, Quality, Engineering, and IT stakeholders to document business processes, support system enhancements, test system changes, and help ensure reliable and compliant system operations. Key Duties and Responsibilities Help configure, test, and deploy MES and other system changes under the direction of senior team members, system owners, and technical teams. Participate in workshops and meetings with Manufacturing, Quality, Engineering, Supply Chain, and IT stakeholders. Support user acceptance testing (UAT),...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Director of Kidney Analytics will provide advanced analytics and data science leadership for strategic commercial initiatives across the U.S. Kidney therapeutic area. This role will use sophisticated analytical, statistical, and data science methods to identify and quantify market drivers, barriers, risks, and opportunities. The Associate Director will lead the development of scalable data products, analytical models, dashboards, and reporting solutions that enable data-driven decision-making across the Kidney business. The ideal candidate combines deep commercial analytics expertise with strong technical and data science capabilities. They will be able to work with large, complex datasets; develop fit-for-purpose models; communicate technical findings clearly;...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Facilities Maintenance Technician performs daily work supporting building operations and maintenance (plumbing, electrical, carpentry, HVAC). This role is expected to monitor the building management system software, and triage and respond to incidents and alarms, conduct facility walks to identify and correct issues, perform maintenance or repair of facilities equipment, install lab gases and/or connections, support space planning and furniture installations, and all other tasks and duties as assigned with minimal supervision. Professional in appearance and the ability to communicate clearly verbally and in writing. The Facilities Operations Technician performs repairs and maintenance to building equipment, machinery, and prepares or...

The MS&T Senior Scientist exercises a high level of experimental productivity contributing to the advancement of projects in pharmaceutical development or commercial manufacturing and may be running chemistry on multiple projects concurrently. This role requires bench chemistry as well as the management of projects, including roles on cross-functional project teams representing MS&T. This role will interpret complex chemistry, may champion new technologies and involve an increasing knowledge of related scientific disciplines, including regulatory and quality compliance. Cross functional association with Analytical Sciences & Technology (AS&T) Supply Chain management (SCM), Quality (QA) and Regulatory is expected, along with change management activities....

The Senior Director, Marketing is accountable for understanding the market landscape and Vertex's position within the market, actively contributing to defining the strategic and performance goals of the portfolio, and tracking performance against those goals. As a people manager, this role may have financial accountabilities and human resource responsibilities for assigned staff. Key Duties and Responsibilities Develops the portfolio strategy, and oversees creation of brand strategies and brand lifecycle activities Oversees development and implementation of strategic and tactical plans for brand Leads team through challenges related to creating external (promotional) communications materials for external use with customers Provides input into...

The Commercial Training Associate Director will be part of the Global Commercial Excellence team and contribute to the development of a marketing competency model, overall marketing excellence, change management initiatives, and innovation. Key Duties and Responsibilities Drives the organizational adoption of the Marketing Competency Model Leads the communication plan and channels in the roll out Works with and influences senior commercial leaders to ensure a consistent message and usage Establishes metrics for what a successful adoption of the competency model entails both globally and locally Works with Learning and Development business partners to ensure the competency model is included in...