Vertex Job Trends

Vertex is seeking a strategic Senior Director to lead AI Product Management within our Commercial Technology organization. This role will be responsible for building and managing a portfolio of high-value commercial AI products that automate operations, accelerate patient access, and enhance customer experience. The Senior Director will define and drive the AI strategy, lead the development and adoption of agentic AI-powered solutions, and collaborate closely with business engagement and platform teams to deliver measurable value. A key focus will be on defining and tracking the impact of AI investments, fostering upskilling and capability building across the functional teams to ensure...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex Pharmaceuticals is looking to hire a Commercial Training Associate Director, Pain on a full-time basis. The AD will report to the Head of Pain Training to develop training materials/curriculum and enhance the skill and knowledge for our US field teams for Pain. The ideal candidate must possess a unique blend of customer-facing field & pharmaceutical training experience, but most importantly scientific aptitude that will enable them to lead through science. The individual must be a strong collaborator to work cross-functionally within the US Commercial Team (Sales, Marketing, Managed Markets) but more importantly across the entire organization (Medical Affairs, HR,...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex is a global biotechnology company that invests in scientific innovation. The Data, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. Role Overview We are seeking a data driven, scientifically literate, and technically skilled Principal Engineer to serve as the Automated Data QC and Reporting...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Senior Manager, GxP Strategic Document Partner supports the Associate Director of GxP Quality Document and Records Management by managing, assessing, and delivering high-impact, compliant documents and records management solutions in alignment with quality objectives, regulatory standards, and business priorities. The Senior Manager serves as a strategic document partner for assigned area(s) and/or quality system(s), leading document impact and needs analyses and partners with the business to lead Global document initiatives, supporting a functional document hierarchy which integrates the development, maintenance, and distribution of critical documents that support the organization’s strategic goals and initiatives. This role requires expertise in consulting,...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

We are seeking a unique individual with a passion for data and AI technology who can help our team drive forward enterprise-scale AI adoption of our data & AI platform. Vertex Pharmaceuticals is in a transformational period where we are accelerating our capabilities, technologies, and data to augment our scientific mission, enable Vertex to grow in scale, and continue to be on the forefront of science, medicine, and technology. As part of this effort, it is critical that users have data “at their fingertips”, with the patterns and technology to support AI adoption at scale. As a Senior Principal AI...

Job Posting Title Senior Manager, Strategy & Operations Market Access Strategy The Senior Manager, Strategy and Operations, US Market Access Strategy is a key partner and advisor to the VP US Market Access Strategy and Market Access Strategy Leadership Team (MAS-LT) on a variety of strategic, operational, and organizational matters. The role requires both strategic thinking as well as the ability to drive project management, and operational execution through preparing, implementing, and effectively managing tactical initiatives. The ideal candidate is a highly motivated and highly organized individual with exceptional emotional intelligence, communication skills and judgment with the ability to...

The Patient Support Communications Senior Manager, Kidney will be responsible for the development and execution of patient and HCP-focused materials that will support our build out of our kidney patient support program(s). A deep passion and curiosity in understanding and supporting the challenges patients face in their lives is imperative. General/ The Patient Support Communications Senior Manager, Kidney is part of the communications team and participates in the day-to-day execution of the patient communications strategy that supports those enrolled in our patient support program. The individual will support the development of our executed communication strategy by developing and/or updating materials...

The Associate Director of Early Pipeline Forecasting & Process will lead commercial forecasting efforts across multiple pre-clinical and early clinical programs, shaping Vertex’s understanding of potential opportunities long before pivotal data becomes available. This individual will build structured, assumption-driven models, stress-test evolving inputs, and synthesize insights across scientific, clinical, competitive, and market research sources. They will collaborate closely with marketing science and external vendors to ensure primary and secondary market research is appropriately interpreted and incorporated into forecasts. The role serves as a key voice across the broader Vertex portfolio—coordinating portfolio-wide analytics during the long-range planning (LRP) cycle, aligning assumptions...

The Senior Director, Project Management and Strategic Operations, is a key leadership role that will provide strategic leadership and direction to the advancement of the framework, capabilities, and sustainability of the compliance function in driving leading practices and keeping pace with the evolving organization and industry. This role will provide strategic direction and oversee the vendor qualification and compliance oversight program across areas ensuring effectiveness of risk management strategies across third parties and internal vendor management. This role will also provide strategic direction and oversee advancement of the inspection readiness framework with responsibility for strategic management and hosting of regulatory...

As a key Team Manager and leader in the Strategic Sourcing function, the Director, Strategic Sourcing CoE Programs & Initiatives Leader is responsible for leading the strategic sourcing organizational through designing and driving key programs for value delivery and organizational AI readiness in partnership with the functional sourcing teams, business, DTE and other key stakeholders, elevating sourcing and procurement impact to the enterprise. The role provides people leadership to elevate the capabilities of the sourcing team, and has responsibility to help shape the future of an AI centered operating model. The ideal candidate understands Vertex systems and processes, is a...

The Director, Quality Analytics is accountable for advancing the Quality Analytics Center of Excellence by delivering trusted, decision‑grade insights across Quality and GxP domains. This role leads a team that designs and scales metrics, dashboards, and advanced analytics to strengthen quality governance, operational oversight, and continuous improvement across modalities and product lifecycle stages. This role is a people manager, responsible for building and developing a high‑performing team, establishing clear priorities and operating rhythms, and ensuring analytics and AI solutions are implemented in a controlled, compliant manner suitable for regulated environments. The role partners cross‑functionally to improve data quality and reliability,...

The Senior Director, Biostatistics will independently perform highly scientific statistical functions in support of a company therapeutic area or areas on new and complex issues. The incumbent will complete work in a resourceful, self-sufficient manner and create alternative approaches to achieve desired results if needed. In addition, the Senior Director provides independent strategic and technical contributions. The incumbent should possess an excellent knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. As a people manager within the organization, may have financial accountabilities and human resource responsibilities for assigned staff. Key Duties and Responsibilities Defines and implements...

Vertex is seeking an experienced and energized consolidation leader with accounting systems and process expertise to join our Global Accounting organization . T he Associate Director, Accounting Systems & Consolidation is responsible for overseeing the team’s performance of monthly consolidation tasks , supporting various process improvement and optimization initiatives, and collaborating with the IT department to enhance and upgrade key accounting systems . The ideal candidate is passionate about leveraging technology to streamline operations, improve efficiency, and modernize accounting processes . Key Duties and Responsibilities Oversee team execution of the global consolidation process, focusing on accuracy and timely preparation of...

The Patient Support Communications Manager, Kidney will be responsible for the development and execution of patient and HCP-focused materials that will support our build out of our kidney patient support program(s). A deep passion and curiosity in understanding and supporting the challenges patients face in their lives is imperative. General/ The Patient Support Communications Manager, Kidney is part of the communications team and participates in the day-to-day execution of the patient communications strategy that supports those enrolled in our patient support program. The individual will support the development of our executed communication strategy by developing and/or updating materials for patients...

Role Overview The Sr. Director, Commercial Technology Business Engagement Leader – Kidney & Patient Services is responsible for executing and operationalizing commercial technology capabilities in direct support of the North America Kidney Business Unit and the Patient Services Program. Reporting the Executive Director, US Commercial Technology this role acts as the day‑to‑day technology leader embedded with Kidney commercial and patient services leadership, accountable for translating business priorities into deliverable roadmaps, funded initiatives, and reliable operations. The Sr. Director ensures that technology solutions—spanning CRM, digital engagement, data, analytics, and AI‑enabled workflows—are implemented effectively, adopted by the business, and operated reliably within...

We are seeking a dedicated and skilled Senior Research Associate to join our Tissue Dissection Group within the Molecular & Cell Biology team in San Diego. The successful candidate will play a critical role in generating high-quality cells from primary human tissues, contributing to various Vertex research programs. This position requires expertise in human tissue dissection, a commitment to excellence, and a deep respect for the gift of donated human tissues. Key Responsibilities Perform dissection of human tissues, including dorsal root ganglia (DRG), lung, and precision-cut tissue slices. Develop and optimize dissection workflows and methods to enhance efficiency and quality....

Vertex currently operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Pain, and the first CRISPR-based, gene therapy for sickle cell disease and transfusion-dependent beta thalassemia. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Type 1 diabetes, APOL-1 Mediated Kidney Disease, IgA nephropathy, Duchenne Muscular Dystrophy, and Alpha-1 Antitrypsin Deficiency (AATD). The Regional Access and Reimbursement Associate Director will help ensure appropriate access and reimbursement of Vertex cellular...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Job Summary Vertex is seeking a highly motivated and experienced Associate Director, Quality Control to join our External Manufacturing, Cell and Genetic Therapies (CGT) team. This role is pivotal in driving quality excellence and operational efficiency across our commercial CGT manufacturing sites and testing facilities. The successful candidate will lead key quality initiatives, develop and execute lifecycle management (LCM) strategies, and champion digital transformation within the Quality Control (QC) function. This is a hybrid role, offering a dynamic and collaborative work environment. Key Responsibilities Develop and execute Lifecycle Management (LCM) strategies to ensure continuous improvement, scalability and compliance across QC...

The Commercial Field Strategy & Execution Associate Director assesses business opportunities and challenges within the kidney field sales business unit. This role entails collaborating with various customer-facing teams and internal stakeholders to maximize commercial opportunities while meeting assigned performance goals. This individual will focus on driving brand performance by leading the development, integration, and implementation of the business planning process for the commercial field team. The role involves close collaboration with marketing, market access, and other key stakeholders to develop and execute strategies within the kidney BU. The Commercial Field Strategy & Execution AD will serve as a liaison between...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Director, Clinical Trial Management is responsible for the planning, oversight, and execution of study and program-level deliverables across a range of study phases within one or more therapeutic areas to ensure corporate goals are met. This role often has responsibility for complex therapeutic areas with multiple compounds under simultaneous clinical development. This role will also manage a high performing global team of Clinical Trial Managers in the fast-paced and expanding Global Clinical Operations (GCO) organization, and may also manage individuals at the Associate Director level who also have program-level responsibilities. This position has a strong affiliation with the GCO...

Qualified candidates Must live within a 25 mile radius of Kissimmee / Lakeland, Florida areas. The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within...

The Pharmacology Research Scientist works with a high degree of independence and is adept at conceptually outlining in vivo and in vitro immunological studies to design, execute and interpret assays to study the action of compounds on disease biology. Completes work in a resourceful, self-sufficient manner and is able to design alternative approaches to achieve desired outcomes. Keeps current on the scientific literature relevant to scientific methodology or field(s) of technical expertise. This level captures both the Research organization’s entry level for staff with a research doctoral degree (PhD) and the advanced experimental expert leading one or more critical laboratory...

As the Field Analytics and Reporting Associate Director , you will be responsible for supporting all field analytics to support the current and upcoming product launches for Vertex. This role reports to the Director of Field Analytics in North America IACO (Insights Analytics & Commercial Operations). This role will support strategy, design, roadmap planning, delivery, and adoption of all analytics across all field roles within the Strategic Customer Engagement Team including Field Account Managers, Regional/Area Managers, Strategic Account Leads, and Virtual Field Representatives. This role will also serve as a critical team member for the Business Unit Analytical Support team...

Vertex is seeking a talented leader to join our US Kidney Business Unit to support our aspirations of bringing Povetacicept and Inaxaplin , Phase 3 investigational therapies that have the potential to transform lives across multiple serious diseases, to patients. The Senior Director, Patient Support Lead will be key to creating the necessary processes, systems, infrastructure, and operations for the Patient Support organization within the US Kidney Business Unit. They will develop the launch strategy , define the appropriate patient support model, recruit and develop a high-performing patient support team and ensure execution of launch activities. This role is a...

The Associate Director, Portfolio Management R&D Quality (RDQ) reports to the Head of Analytics & Centers of Excellence (ACE) and provides operational leadership and oversight for the successful execution and delivery of all R&D Quality (RDQ) initiatives across the business portfolio. Supporting all RDQ and Quality Assurance (QA) business units, these initiatives focus on implementing effective business tools, systems, and processes to establish a robust governance model and a data‑rich environment that drives operational excellence, process optimization and automation, informed study oversight, transparent and proactive portfolio and program governance, and strategic, evidence‑based planning and prediction. With additional responsibilities for staff...

The Senior Director, Regulatory Submission Management champions functional and cross-functional project and submission management excellence. The incumbent is expected to apply deep subject matter expertise in project and submission management to lead and identify opportunities, shape objectives and drive execution of key functional and corporate objectives. This role will be responsible for driving timeline risk mitigation and contingency planning. Key Duties and Responsibilities Provide strategic and operational project, submission and program leadership activities at all stages of the lifecycle (initiation through closeout). Drive communication cross-functionally and with senior leaders on project, submission and program planning topics including timelines, status, risks...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex

Vertex is seeking an experienced commercial leader to implement field sales and non-personal promotion tactics in support of the Pain Business Unit (BU). The Customer Strategy & Execution Lead (CSEL) will partner with North America commercial organization to implement the go-to-market (GTM) strategy and deliver customer solutions that meet the business needs. This role will work directly with the BU stakeholders, Field Operations Leads, Digital Operations Leads, Customer Data Management, and technical stakeholders to optimize HCP customer experience. This role reports to the Director, Customer Strategy & Execution Lead. Key Duties and Responsibilities Partner with key business leaders to understand...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

The Medical Affairs Strategy Medical Director will provide medical leadership for the Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of IgA Nephropathy (IgAN), that has best-in-class and pipeline-in-a-product potential across a variety of autoimmune diseases. This role will be responsible for developing the medical strategy and medical plan under the direction of the VP/Executive Director, as well as executing against the medical plan encompassing the pove programs. This role will collaborate closely with cross-functional groups to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs,...

The Executive Director (ED), North America Commercial Operations leads a team that supports multiple in-line disease areas, supporting each US Business Unit and their respective leadership teams within North America Commercial. The ED oversees 5 district functions Commercial Data Management, Field Operations, Marketing Operations, Field Training, and Business Engagement Leads. This position reports to the Vice President, North America Commercial Operations, Insights & Analytics and is located at our headquarters in Boston, MA in the Seaport area. Key Duties and Responsibilities Leads 5 distinct functions Commercial Data Management, Field Operations, Marketing Operations, Field Training, and business engagement leads in support...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Commercial Data Management Senior Manager, Pain, is responsible for contributing to the coordination, design and delivery of the commercial data activities that enhance customer engagement and facilitate data driven decision making for the Pain therapy business unit. Key Duties and Responsibilities Acts as an advisor and coach for and collaborates with the governance team(s) Manages data services vendors Supports the training of internal teams on processes and procedures, including CRM Collaborates with Global Information Systems (GIS) team regarding implementation of fixes and enhancements Partners with Sales and Marketing teams to manage and administer content update requests Manages HCP-to-HCO affiliations...

We are seeking an innovative and highly motivated Senior Scientist to lead discovery-stage development of targeted lipid nanoparticle (LNP) platforms. This role will drive receptor target identification and validation, establish high-throughput ligand conjugation workflows, and develop scalable assay systems to enable systematic screening of targeted LNP constructs. The successful candidate will build a modular, data-driven targeting engine capable of evaluating single and multi-ligand strategies across multiple cell types and therapeutic indications. This is an onsite position in San Diego. KEY RESPONSIBILITIES Receptor Target Identification & Validation Identify and prioritize cell-surface receptor targets aligned with disease biology and delivery feasibility. Integrate...

Vertex

The Senior Administrative Assistant provides experienced office/business support to a department. The Senior Administrative Assistant generally reports directly to a(n) Country Manager, Executive Director or Vice President-level manager. Key Duties and Responsibilities Manages calendars for assigned personnel, including meeting scheduling (both internal and off-site meetings), accepting/declining invites, meeting prioritization, securing conference rooms, ordering catering and "day-of" logistical and administrative support Serves as a departmental resource for Vertex's internal technologies (i.e; Procurement, SharePoint, Concur, Vertex U, VLearn, etc.) Exchanges and integrates information from stakeholders into departmental reports Books flights/hotels, completes expense reports, and arranges team lunches/dinners and offsite meetings for assigned...

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group in Boston, MA. The Health Economics & Outcomes Research Senior Manager will participate in the development and execution of Health economics and outcomes research studies in support of Vertex's products. This position reports to the Director HEOR, Pain. Key Duties and Responsibilities Executes HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value Provides...

The Senior Administrative Assistant provides experienced business support to the Quality department, reporting directly to a Vice President. The role is responsible for core administrative duties including calendar management, budget planning, and partnering with other assistants to drive continuous improvement. A primary focus of this position is establishing and leveraging digital technologies and AI to enhance task execution and optimize departmental workflows. Key Duties and Responsibilities Ensures seamless execution of day-to-day activities including proactive calendar management, meeting prioritization, and logistical support. Serves as a departmental resource for internal technologies such as SharePoint, Procurement, and Concur. Books travel logistics and completes...

The Patient Safety Associate Medical Director will provide medical safety expertise, state of the art pharmacovigilance, and safety risk management for assigned products (marketed or in development). This role will optimizes patient safety of Vertex products and maintenance of compliance with the Pharmacovigilance regulations of Regulatory Agencies around the globe, through the effective and timely completion of Safety activities through the product life cycle. Key Duties and Responsibilities Provides medical safety expertise, state of the art pharmacovigilance, and safety risk management for assigned products (marketed or in development) Responsible for the safety assessment activities of assigned products under the supervision...

Reporting to the Senior Director, Contract Operations, this role is responsible for the lifecycle management process of agreements within the US Market Access Organization (Commercial and Government (ex Medicare Advantage and Part D)) Full Line Wholesalers, Specialty Distributors, Specialty Pharmacies, Group Purchasing Organizations, PBMs, and other segments and channels as required. This position will work closely with the Senior Director, Contract Operations and cross-functional leaders to ensure agreements meet business, legal, operational and compliance needs across several therapeutic areas. The ideal candidate will be familiar with and highly conversant in various segments of market access, discuss and incorporate contracting strategies...

The Director, Congress, Ad Board, and Strategic Council Lead, US Kidney is responsible for setting the strategic direction, planning, and flawless execution of congresses, advisory boards, and strategic councils for povetacicept and inaxaplin to support our launches in IgA nephropathy (IgAN) and APOL1-mediated kidney disease (AMKD). This leader will define and oversee the immediate and long-term vision for the company’s presence and influence across 50 regional and national conferences, ensuring alignment with the overall brand strategy and business objectives. Additionally, this person will be responsible for engaging with Key Thought Leaders (KTLs) to plan and execute high-impact ad boards and...

We are seeking a visionary People Research Associate Director to lead the design and execution of high-impact research initiatives that shape workforce strategy and elevate organizational effectiveness. This role demands deep expertise in experimental methods, program evaluation, and storytelling with data. The People Research Associate Director will hold a PhD in a relevant field and bring a strong track record of translating complex research into actionable insights for senior leadership. Key Duties and Responsibilities Lead End-to-End Research Design Architect and execute research studies to evaluate the effectiveness of HR programs, policies, and interventions. Plan, design and conduct experiments to understand...

Vertex Pharmaceuticals, Inc. is seeking a highly skilled and proactive Principal Research Associate to join our Human Cell Core, contributing to the development and execution of advanced human cell models at scale. The ideal candidate is an expert experimentalist who excels in a fast paced , team-oriented environment and operates with a high level of scientific rigor and independence. This role involves maintaining and expanding primary human cells at scale, operating automation-enabled cell culture platforms and executing functional assays to support cell optimization and troubleshooting efforts. Success in this position requires exceptional reliability, attention to detail, adaptability, problem solving skills...

The Senior Manager, GxP Strategic Training Partner (STP) serves as a dedicated strategic partner to assigned operational or functional business areas, responsible for translating business needs and regulatory expectations into effective, practical, and inspection-ready learning solutions. This role operates as part of a Strategic Training Partner (STP) model led by the Associate Director, GxP Training & Learning Strategy. STPs are expected to be experts in adult learning and deeply knowledgeable in the business areas they support, enabling them to diagnose needs, challenge assumptions, and design learning approaches that improve execution—not just training completion. The STP is accountable for shaping learning...

The Senior Quality Manager will be part of the Program Quality Team in Vertex’s North America Commercial Patient Support Program Center of Excellence (NAC PSP COE). The COE is a group of compassionate and determined individuals who provide operational support to our commercial Patient Support Programs (Cystic Fibrosis, Hematology, Diabetes and Kidney) in areas such as systems and technology, data and analytics, vendor management and program quality. Additionally, COE team members help design patient support offerings and policies for future Vertex Patient Support Programs (PSP). The Senior Quality Manager will play a meaningful role within the COE and contribute to...

The Clinical Pharmacology Director leads strategic, scientific and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the development of clinical pharmacology plans; assists in departmental management through program reviews and collaborative decision-making; supervises asset leads, provides career development; routinely co-leads cross-functional efforts and leads department initiatives. Key Duties and Responsibilities Responsible for the application of clinical quantitative pharmacology strategy to support the immunology portfolio. Guides metabolic, co-dosing and drug-drug interaction issues, collaborating closely with cross functional colleagues. Co-leads or serves on cross-functional committees and/or contributes...

The Associate Director, Marketing Operations – Speaker, Exhibit, and Sponsorship Platform role serves as the strategic lead for North American commercial peer-to-peer programming and congress exhibit, sponsorship activities. Overseeing effective healthcare professional engagement in support of business unit objectives. Establishing capabilities and process to manage the end-to-end speaker lifecycle, contracting, and payment reconciliation for exhibits, sponsorships, and memberships. This role bridges brand objectives with operational excellence to accelerate education while maintaining adherence to global compliance requirements. Key Duties and Responsibilities Speaker Lifecycle & Contract Management Lead the execution and resolution process for a business unit speaker contracts and manage the...

Position Overview The Payer Account Director–Government Accounts (PAD-GA) leads national payer and PBM strategies to secure optimal access and reimbursement for Vertex’s commercialized products in Federal and State Medicaid channels. This includes ensuring appropriate pharmacy and medical benefit policies, building relationships with key decision-makers, negotiating contracts, and aligning Vertex’s value with payer priorities. As the primary contact for assigned national accounts, the PAD-GA drives market access, supports sales across Business Units, and ensures strategic alignment to improve patient access and brand performance. The role involves collaborating with Payer Account Associate Directors (PAADs) and Payer Account Directors (PADs) to develop and...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

Company Overview Vertex is growing at a rapid pace with exciting opportunities for motivated professionals who want to contribute to our mission to invest in scientific innovation to create transformative medicines for people with serious diseases. Our Finance function plays a critical role in delivering on this mission by shaping strategy, enabling informed decision making, and providing deep business insight to support value creation across the enterprise. The Senior Director of Commercial Finance is a senior leader within the US Commercial Finance organization and serves as the primary strategic business partner to the U S Commercial Vice President and...

The External Manufacturing Associate Director role is a key member of Vertex’s External Manufacturing Organization (ExM), providing support, strategic insights and enterprise thinking to the Biopharmaceutical Sciences and Manufacturing Operations organization (BSMO). This leader will cultivate and leverage multiple cross-functional business relationships to identify and execute creative solutions to organizational opportunities and challenges. This role will be responsible for managing a subset of the Small Molecule Drug Product external network of Contract Manufacturing Organizations (CMOs). Key Duties and Responsibilities In partnership with Supply Chain, MSAT, Quality and Finance, develop external manufacturing production plans and drive plans to execution (on time...

Vertex is seeking a talented and experienced leader to join our Analytical Development Team to lead Biologic project CMC analytical development activities. The experienced leader will play a central role in advancing our biologics projects by executing development activities through a combined internal and external network. The individual is expected to closely work with external partners in developing and executing the development activities of biologics from the discovery interface to first license approval and beyond. The individual is expected to lead the execution of analytical activities according to phase appropriate development strategies. The successful candidate must work well in a...