Vertex Job Trends

The Patient Support Communications Associate Director, Kidney will be responsible for the development and execution of patient and HCP-focused materials that will support our build out of our kidney franchise patient support program focused on AMKD. A deep passion and curiosity in understanding and supporting the challenges patients face in their lives is imperative. You must be an individual who also embraces supporting patients in underserved and diverse patient populations. General/ The Patient Support Communications Associate Director, Kidney is part of the PSP Marketing team and participates in the day-to-day execution of the patient communications strategy . This individual will...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Director of Solutions Architecture to join our team and drive our digital transformation initiatives. The Director, Solutions...

The Director, Global Patient Safety Individual Case Safety Report (ICSR) oversees global ICSR processing and external PV partners and vendors. This position manages the technical aspects of end-to-end safety case intake, processing, quality control, and regulatory submissions within a therapeutic area (as assigned) covering the applicable drug, biologic, medical device, and combination products, ensuring operations are consistent, compliant, and inspection-ready worldwide. The Director, Global Patient Safety Individual Case Safety Report (ICSR) plays a key role in global ICSR processing excellence and external business management. This position serves as a subject matter expert in pharmacovigilance (PV) and contributes to developing and...

Vertex’s Data, Technology and Engineering (DTE) organization is seeking a Technology Portfolio Management Director to join our Project Management and Strategic Operations (PMSO) team. Project Management and Strategic Operations is charged with streamlining and simplifying the work of our data and technology teams and ensuring the successful deployment of new technologies across our global enterprise. The Director, Information Security Technology Portfolio Management will report to our Senior Director of Project Management and Strategic Operations and partner directly with our Chief Information Security Officer to oversee the Information Security project portfolio of new technology implementations. The role requires portfolio planning, financial...

General/ The Director of Analytical Product Quality, is responsible for the quality oversight of analytical development activities throughout the product development lifecycle for Cell & Genetic therapy programs. This role includes Quality Assurance support to cross-functional partners for the method validation of applicable analytical methods and support on analytical transfer activities to contract manufacturers, test labs and internal laboratories as applicable. The role will closely partner with operational stakeholders to participate in Cell & Genetic therapies projects to meet business, regulatory and operational requirements. Key Duties & Responsibilities Proactively maintain Quality Assurance oversight of the method development, and qualification activities...

The Kidney Territory Account Manager (KTAM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs), developing a strategic business plan, communicating thorough disease and product knowledge to HCPs and centers of care. This role must understand market dynamics in rare, complex disease states, demonstrate excellent judgment, and be motivated by the desire to improve patients' lives. The KTAM will report into a Regional Field Leader (RFL) and is responsible for leading engagement with nephrologists and serving as an account manager for specialty kidney clinics. Key Duties and Responsibilities Establishes meaningful and professional relationships with nephrologists and related...

The Project Management Director serves as the operational backbone of the GCO Digitization Strategy Center of Excellence, responsible for orchestrating the end-to-end portfolio of transformation initiatives across 6 workstreams, 50+ participants, and 10+ functional team transformation roadmaps. This role combines program management, value realization, and executive reporting into a single, high-impact position. The Director partners with GCOLT, DTE, and GCO functional leaders to ensure transformation initiatives are delivered on time, cross-functional dependencies are managed, risks are proactively mitigated, and business value is measured and communicated to leadership. This role is critical to ensuring the COE can scale its impact while...

The Patient Safety Associate Medical Director will provide medical safety expertise, state of the art pharmacovigilance, and safety risk management for assigned products (marketed or in development). This role will optimizes patient safety of Vertex products and maintenance of compliance with the Pharmacovigilance regulations of Regulatory Agencies around the globe, through the effective and timely completion of Safety activities through the product life cycle. Key Duties and Responsibilities Provides medical safety expertise, state of the art pharmacovigilance, and safety risk management for assigned products (marketed or in development) Responsible for the safety assessment activities of assigned products under the supervision...

Vertex is a global biotechnology company that invests in scientific innovation. The Data, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing and Supply (RPMS) group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Associate Director of Laboratory Engineering and Technology Site Lead West Coast (LE&W) to join our team and...

The Associate Director, GxP Operations Support Lab Systems will be responsible for supporting documentation and electronic systems related to manufacturing and quality control at the Vertex Manufacturing Center (VMC). This includes overseeing the writing and editing of SOPs, WIs, batch records, training content, and other related documentation, batch record and analytical data review, quality event ownership, and support of MES, LIMS, Tulip, and electronic training. This position also includes group supervision and management. Key Duties and Responsibilities Management and ownership of deviation, CAPA and Effectiveness Check (EC) and Change Control (CC) records in electronic Quality Management System (eQMS) Identify and...

Vertex Pharmaceuticals is seeking to hire a Patient Educator Senior Manager - WEST to join our growing team. The ideal candidate will reside in one of these metropolitan areas Los Angeles or San Francisco metro areas. This is a field based role and candidates must currently reside in the Western Region of the United States. This Patient Educator will report to the Director, Patient Educators and is responsible for providing people living and affected by sickle cell disease (SCD) and beta thalassemia (BT) with education, tools, and resources that help them have meaningful discussions with their healthcare providers. This team...

At Vertex, we’re driven by a shared purpose to transform the lives of patients with serious diseases. The Executive Director, MSAT will provide strategic and hands-on leadership for Manufacturing Science & Technology (MSAT) across our Type 1 Diabetes cell therapy manufacturing network. This role is accountable for process performance, technical transfer, validation, continued process verification, comparability, and lifecycle management —with a particular focus on external manufacturing partners (CMOs) . You will build and lead a high-performing MSAT organization that bridges Process Development and GMP Manufacturing, ensuring processes are robust, scalable, compliant, and inspection-ready from early clinical supply through commercialization. This...

At Vertex, we are driven by a shared commitment to transform the lives of patients with serious diseases. The Executive Director, Manufacturing Operations will play a critical leadership role in delivering on this mission by building and leading a global external manufacturing network for our Type 1 Diabetes cell therapy programs. This role is accountable for the strategy, governance, and operational oversight of Contract Manufacturing Organizations (CMOs). The leader will operate as a strategic partner to these organizations, ensuring the highest standards of quality, reliability, and scalability to support clinical development and commercialization. Key Duties and Responsibilities External Manufacturing Strategy...

The Senior Administrative Assistant provides high-level administrative and operational support to leaders within Commercial Manufacturing & Technical Operations (CMTO). The role enables efficient execution of CMTO priorities by managing complex logistics, supporting cross-functional coordination, and ensuring seamless day-to-day operations. This position plays a critical role in enabling leadership effectiveness, driving organizational alignment, and supporting key business priorities across CMTO. Key Duties and Responsibilities Manages complex calendars for CMTO leaders, including prioritization of meetings aligned to business criticality across manufacturing, supply chain, and technical operations Coordinates internal and external meetings, including governance forums, offsites, and cross-functional sessions; manages logistics, materials, and...

The Modeling & Simulations Associate Director will be responsible for developing and executing M&S strategies and activities in cross functional drug development project teams in close collaboration with colleagues in Clinical Pharmacology, Biostatistics, Research and other colleagues within the R&D organization. This role determines, plans, and executes technically challenging analyses by using state of the art Modeling & Simulation methodologies to strongly contribute to critical decision making. Key Duties and Responsibilities As Modeling & Simulations (M&S) lead in one or more cross functional drug development teams, responsibilities include the development and execution of Modeling & Simulation plans and analyses fully...

The Strategy & Operations Associate Director is a strategic leadership role responsible for translating enterprise and disease area strategies into Cell & Genetic Therapy (CGT) Research-specific execution plans. This role facilitates leadership decision-making and serves as the bridge between Leiden Campus (LC) Research and critical cross-functional partnerships. Bringing a strong combination of scientific and business acumen, the Associate Director advances multiple cross-functional strategic initiatives across Leiden Campus and Cell & Genetic Therapy (CGT) Research. Partnering closely with senior leaders within and outside LC Research, the role helps shape strategic direction, secure alignment, and drive execution against shared goals and priorities....

General/ Vertex is in an exciting time of growth and innovation, and technology and data are valued as strategic assets for the organization. The North America Commercial Operations CRM Field Operations Team is looking for an Associate Director, CRM Field Operations to ensure continued customer centricity and success. The Associate Director, CRM Field Operations plays a critical role between the cross-section of sales and marketing and a close partnership with other business functions. The primary responsibility of this position will be to support designated BU HQ and Field teams with the continuous improvement of the customer relationship management (CRM) system....

The Senior Manager, FP&A is a key member of Vertex’s Finance Business Partnering organization, providing financial leadership and strategic support to the U.S. Kidney team. As Vertex advances toward commercialization of its Kidney portfolio, this role will help shape and deliver near-term and long-term financial goals. This position will play a critical role in supporting pre-launch and post-launch resource allocation in the U.S., a priority market for the Kidney portfolio. The Senior Manager will partner across Finance, Marketing, Sales, Patient Support, Market Access, and other supporting functions to deliver actionable insights, inform decision-making, and help define the key performance indicators...

We are seeking a strategic, influential Senior Director, HR Business Partner to lead the people strategy for Vertex’s Data, Technology & AI (DTE) organization. This role partners closely with the Chief Digital & Information Officer (CDIO) and leadership team to translate business and technology priorities into an integrated talent and organizational agenda . The position plays a critical role in enabling execution of the Data/Technology/AI roadmap through leadership capability, operating model evolution, and enterprise talent strategy. Key Duties & Responsibilities Strategic HR Partner Serve as the primary HR partner to the CDIO and DTE leadership team, translating strategy into prioritized...

Biostatistics Associate Director will perform sophisticated scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with minimal guidance and mentoring on new and complex issues. The incumbent will completed work in a resourceful, self-sufficient manner and create alternative approaches to achieve desired results. The incumbent is capable of independent strategic and technical contributions. The incumbent should possess a good knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. Key Duties and Responsibilities Conducts all scientific and operational statistical work for multiple clinical trials, observational studies, or real world data (RWD) investigations....

The International Pharmacovigilance (PV) Specialist is responsible for supporting management of the GPS International PV structure. The International PV Specialist works with a moderate level of supervision and helps troubleshoot problems and improve internal procedures, to ensure compliance with applicable regulatory requirements. Key Duties and Responsibilities Assists with ensuring that all GPS procedures are compliant with global PV regulations Contributes to vendor oversight activities Supports the oversight of local Qualified Persons for Pharmacovigilance (QPPVs) Researches PV regulations and guidelines Reviews, assesses, and tracks global PV regulatory intelligence Reviews PV agreements which support local and regional PV requirements Works cross-functionally to...

Vertex is seeking an Analytics & Insights Manager to join the Supply Chain Operations, Resilience, and Efficiency (SCORE) team. This role will partner with supply chain stakeholders across all disease areas to understand reporting needs, define meaningful metrics, and deliver scalable reports and dashboards that support effective decision-making and improve business performance. The individual will work cross-functionally with Finance, ExM, Quality, DTE (Data & Tech), BAR, and other business partners to align on KPIs, reporting definitions, data sources, and analytics priorities. KEY RESPONSIBILITIES Lead supply chain reporting and analytics initiatives from requirements gathering through implementation, adoption, and continuous improvement. Contribute...

The Trade and Distribution Operations Manager is responsible for supporting key trade operations activities across product returns, distribution management, regulatory request processing, and quality documentation. This role partners cross-functionally with Revenue Accounting, Government Pricing, Trade Account Management, Quality, and external distribution partners to ensure compliant, efficient, and accurate execution of trade and distribution processes. The ideal candidate will bring strong operational expertise within the pharmaceutical or biotechnology industry, with experience managing third-party logistics providers, supporting regulated distribution processes, and driving cross-functional resolution of trade-related issues. This role is expected to operate in an on-site or hybrid work model. Key Duties...

The Senior Manager (SM) of Customer Master Data Management reports to the Director of Customer Master & Commercial Data Management in the Commercial Innovation Analytics Operations (CIAO) organization. This individual supports the Global Healthcare Entity Master system (GHEM) and will help drive the customer mastering process, working with a team of data stewards, and supporting overall data governance at Vertex. The ideal candidate is passionate about data, has experience managing data quality and master data initiatives, and understands MDM’s role in enabling and building a 360⁰ view of customers in an enterprise. Key Duties and Responsibilities Support the overall global...

The Kidney Territory Account Manager (KTAM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs), developing a strategic business plan, communicating thorough disease and product knowledge to HCPs and centers of care. This role must understand market dynamics in rare, complex disease states, demonstrate excellent judgment, and be motivated by the desire to improve patients' lives. The KTAM will report into a Regional Field Leader (RFL) and is responsible for leading engagement with nephrologists and serving as an account manager for specialty kidney clinics. Key Duties and Responsibilities Establishes meaningful and professional relationships with nephrologists and related...

The Senior Director, Global Quality Systems holds a pivotal leadership position within the Quality organization. This individual is responsible for providing strategic vision and direction to advance the framework, strengthen organizational capabilities, and ensure the sustainability and effectiveness of the Quality Management System. The role is instrumental in promoting leading practices and supporting the organization's growth as well as adapting to industry changes. This leader provides strategic leadership and oversight across all aspects of Global Quality Systems. This includes guaranteeing the integrity and effectiveness of the framework, enhancing capabilities, and ensuring robust execution throughout GxP domains, various products, modalities, and...

The Senior Manager of Cold Chain Logistics Process is responsible for leading the development and implementation of processes and procedures to ensure the success of cold chain logistics operations within Vertex Pharmaceuticals. This position requires close collaboration with logistics service providers, order management teams, quality assurance, packaging engineering, and other stakeholders to ensure adherence to regulatory guidelines and meet business needs. The Senior Manager will be an integral member of the logistics team, working to develop a robust logistics network to support pipeline programs, evaluate and launch logistics and supply chain information systems, and manage all quality systems from open...

Vertex is seeking a talented leader to join our US Pain Business Unit to support our journey to bring forth new options for the treatment of pain. The Senior Director, US Pain HCP Marketing will lead HCP marketing team for the US Pain Business Unit alongside a team of direct reports, which is launching JOURNAVX, a novel selective pain signal inhibitor of NaV1.8 in acute pain. This role will drive the evolution and implementation of our HCP marketing strategy , supporting the launch through a lean in person presence supplemented by robust digital engagement. This individual will develop/refine the HCP...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The MSAT Senior Scientist (Investigations and Strategic Projects) is responsible for leading complex technical investigations, driving strategic process improvements, and fostering a culture of continuous improvement within manufacturing operations. This role will leverage Six Sigma methodologies, including DMAIC, and lead complex technical investigations utilizing statistical methods and multivariate analysis to understand and identify contributing factors influencing manufacturing outcomes. In addition, this position will drive strategic improvement initiatives across manufacturing operations as a form of continuous improvement. The incumbent will collaborate cross-functionally with Quality, Engineering, Manufacturing, Process Development and Regulatory teams to ensure robust root cause analysis (RCA), effective corrective and...

Vertex is seeking a strategic and collaborative leader to join the US Pain Business Unit to support our journey to bring forth new options for the treatment of pain. The Director, Key Thought Leader (KTL) Strategy & Professional Organizations will play a critical role in shaping and executing Vertex’s engagement strategy with key thought leaders and professional organizations to support the continued launch and growth of JOURNAVX, a novel selective pain signal inhibitor of NaV1.8 in acute pain. This role will be responsible for building and leading a comprehensive KTL engagement strategy, strengthening partnerships with professional societies, and advancing initiatives...