Vertex Job Trends

The Senior Principal Analyst, Source-to-Pay Technology will provide functional and technical expertise, partnership, and cross-functional support focusing on the Source-to-Pay process, including but not limited to Contract Lifecyle Management and Healthcare Entity Engagement tools. The role will focus on the initial implementation and subsequently support of the platforms. Primary responsibilities include collaborating with business partners on the entire Source-to-Pay process to identify and prioritize opportunities to improve business processes with technology and data, gathering and refining requirements, determining options for solution design, delivering enhancements, supporting integrations, and contributing to technology-driven projects and initiatives. Key Duties and Responsibilities Serve as a...

We are seeking a highly motivated computational biologist with a strong background in computational methods development to join Vertex. This position is part of a rapidly growing Data and Computational Sciences team focused on developing therapies for diseases with serious unmet need. You will play a critical key role in developing cutting-edge computational methods that assess the safety and efficacy of transformative therapeutics. You will also cross-functionally collaborate to develop robust and scalable workflows that address strategic questions across Vertex’s programs. A strong background in computational methods development, a proven track record in Python programming and an ability to seamlessly...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Re Research, Pre-Clinical, Manufacturing and Supply (RPMS) group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Director, Data Compute and Consumption Solutions to join our team and drive our digital transformation initiatives....

We are seeking a dynamic and experienced Associate Director, Platform Lead, to join our commercial DTE team to enable technology & architecture for patient services for current CF and future launch Kidney BU. The Platform lead will be responsible for the design & maintenance of secure, scalable, and reliable patient services solution(s) that align with the business strategy for patient services ecosystem. Collaborate with a cross-functional team to define overall platform roadmap for patient services for CF and Kidney BU. The platform lead will drive the architectural vision, strategy, and execution of technology solutions that enable innovation, efficiency, and compliance,...

The Senior Director of External Manufacturing Operations (Drug Product), provides vision, leadership and management of Vertex’s commercial external manufacturing small molecule network. Managing the external manufacturing network is a critical component of the Commercial Manufacturing and Supply Chain team’s role in ensuring that the company effectively and efficiently delivers medicines to patients. This visionary leader will also cultivate and leverage multiple cross-functional business relationships to identify and execute creative solutions to organizational opportunities and challenges. The Senior Director of External Manufacturing Operations reports directly to the Vice President, Small Molecule External Manufacturing Operations and leads a diverse team of direct...

This Commercial Manufacturing and Supply Chain (CMSC) Business Analytics and Reporting (BAR) Associate Director will be responsible for acting as a business analyst for leading and driving complex cross-functional operational analytics solutions for the Manufacturing & Supply Chain organization to drive data-driven decision making . The position will act as a bridge between the CMSC business functions and IT enablement functions to capture CMSC cross-functional operational business needs and ensure that they are translated to use cases and technical requirements. Business functions include various groups in CMSC – Supply Chain, External Manufacturing, Technical Operations, QC – as well as functions...

General position summary The Associate Director, QMS Event and CAPA Management - Process Excellence, will be a key contributor in the GxP Process Operation Center (GPOC) and have overall responsibility for driving improvements to the Event and CAPA quality management system including processes, systems, governance and key performance indicators (KPIs). This role is primarily responsible for Process Ownership for the Event & Capa Management processes but will also support other QMS (Quality Management System) areas. This includes oversight for the end-to-end processes (e.g.) in the design, deployment, oversight and monitoring of the Event and CAPA Global Quality Systems for performance...

Vertex is growing at a rapid pace with challenging and exciting opportunities for motivated professionals who are keen to contribute to the Vertex mission to invest in scientific innovation to create transformative medicines for people with serious diseases. Over the last few years we have evolved a robust and complex R&D pipeline which requires a focus on efficiency and prioritization as we scale. Our finance function is integral to achieving our company’s strategic goals, providing critical insights and analysis in support of decision-making across the organization. We are making heavy investments in our ability to provide data-driven insights by organizing...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Development, Manufacturing & Supply (RDMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Associate Director of Laboratory Engineering and Technology Site Lead West Coast (LE&W) to join our team and...

The Associate Director, MSAT (Investigations and Strategic Projects) is responsible for leading complex technical investigations, driving strategic process improvements, and fostering a culture of continuous improvement within manufacturing operations. This role will leverage Six Sigma methodologies, including DMAIC, and lead complex technical investigations utilizing statistical methods and multivariate analysis to understand and identify contributing factors influencing manufacturing outcomes . In addition, this position will drive strategic improvement initiatives across manufacturing operations as a form of continuous improvement . The incumbent will collaborate cross-functionally with Quality, Engineering, Manufacturing, Process Development and Regulatory teams to ensure robust root cause analysis (RCA), effective...

As a Director Biostatistics at Vertex, you will be at the forefront of cutting-edge medical research, analyzing complex data to unravel crucial insights that may lead to innovative medical breakthroughs. The Biostatistics Director will independently perform highly scientific statistical functions in support of the company’s Immunotherapies program area on new and complex issues, creating alternative approaches to achieve desired results if needed. In addition, the Director provides independent strategic and technical contributions. The incumbent should possess an excellent knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. T his position is hybrid, with a work schedule...

The Analytical Development Senior Research Scientist consistently demonstrates a high level of strategic planning and experimental execution, working within established timelines. Works with a high degree of independence and demonstrates the ability to lead a team, either formally or informally, to achieve experimental and organizational goals. Takes a leading role in writing documents (method documents, protocols, reports) and demonstrates high-level analytical skills and understanding of data interpretation. Actively seeks cross-functional roles to improve communication between groups and achieve efficiency in achieving organizational deliverables. Key Duties and Responsibilities Evaluate and develop molecular-based assays to evaluate DNA, genome integrity, and RNA characteristics...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing and Supply (RPMS) group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Director, External Manufacturing Solutions to join our team and drive our digital transformation initiatives. The Director, External...

The Senior Director, Global Medicines Development Technology will lead a team responsible for planning, architecture, design, development, support, maintenance and future roadmaps for systems supporting the Global Patient Safety (GPS), Clinical Development, Biometrics, and Real-World Evidence (RWE) teams at Vertex. The incumbent will collaborate with senior leaders and other key stakeholders across these areas of the business, as well as peers across the Data, Technology and Engineering (DTE) organization, to identify, prioritize, design and deliver technology solutions in support of their goals and objectives. KEY RESPONSIBILITIES Partner with business stakeholders across GPS, Clinical Development, Biometrics, and RWE teams to manage...

The Senior Principal Analyst, Medical Writing will provide functional and technical expertise, partnership, and support for the Medical Writing function at Vertex. Primary responsibilities include collaborating with business partners to identify and prioritize opportunities to improve business processes with technology and data, gathering and refining requirements, determining options for solution design, delivering enhancements, supporting integrations, and contributing to technology-driven projects and initiatives. KEY RESPONSIBILITIES Collaborate with Medical Writing business stakeholders to understand their current and future state strategy, needs and requirements from a global perspective Proactively offer solution ideas and potential business process improvements in pursuit of driving efficiencies and...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing and Supply (RPMS) group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Director, Chemistry Solutions to join our team and drive our digital transformation initiatives. The Director, Chemistry Solutions...

We are seeking a unique leader with a passion for data and technology – responsible for leading and managing our growing delivery & operations team that manage and enable Vertex’s Clinical Data Standards & Electronic Data Capture (EDC) solutions enterprise wide. As part of the Data & Software Engineering Team (DSE) you will enable our Clinical Data Management & Study Teams with accurate and secure information to analyze trials using our centralized platform. Vertex Pharmaceuticals is in a transformational period where we are accelerating our capabilities, technologies, and data to augment our scientific mission, enable Vertex to grow in scale,...

This Commercial Manufacturing and Supply Chain (CMSC) Senior Project Manager will be responsible for supporting the cross-functional project teams executing our development CMC and CMSC strategies within the POVE program. The position will partner with the Program Management, CMC functional leads and interface directly with CDMOs to manage cross-functional planning and execution of late-stage development program through commercialization. This role will provide operational expertise as part of program management function to lead strategic planning and drive integrated execution for Biologics drug substance manufacturing, process validations, BLA filing and launch readiness. He/she will partner with cross-functional team to lead development and...

The Portfolio & Program Management Senior Director is a global role within the Portfolio & Program Management (PPM) organization. The incumbent is responsible for championing cross-functional program management excellence to programs across the drug development lifecycle (Research, Pre-clinical and Clinical Development, Registration and Commercialization). The incumbent is expected to apply deep subject matter expertise in project management to identify opportunities, shape objectives and drive execution of global strategy for cross-functional drug development teams. This role is a key leadership position providing strategic and operational project management leadership to the Muscular Dystrophy (MD) Disease Strategy Team (DST). Key Duties and Responsibilities...

Vertex is seeking an experienced technology leader to lead the strategy, planning, and delivery to support the Medical Affairs business function across all disease areas and regions. The AD, Business Engagement & Technology will primarily partner with Global Medical Affairs (GMA) and Medical Operations organizations to create and execute technology strategy in concert with business strategy. This role will work directly with the business partners in global medical affairs organization to understand the business needs and vision and will be accountable for defining technology roadmaps, identifying solutions, and finding synergies across other commercial, medical, and external affairs technologies. Key Duties...

This position provides intermediate legal and contracting support for assigned functions such as commercial, general, administrative, or clinical. Key Duties and Responsibilities Draft and review, with minimal Counsel supervision, a range of contracts, including confidentiality agreements, service agreements and other related agreements. Interpret existing contracts and advise on contract interpretation issues, with support from Counsel as needed. Support and provide leadership for ongoing company-wide initiatives, including contracting processes and adoption of contract-related technologies. Maintain global inventory of contract templates, as well as manage and implement requests for new and updated templates across the company. Train and guide legal colleagues and...

The Senior Director, Clinical Pharmacology will serve as a Disease Area leader for Clinical Pharmacology. The Senior Director, Clinical Pharmacology will also manage the scientific functions and coordinate the activities of the Clinical Pharmacology function in collaboration with the other Disease Area leaders. The role’s responsibilities will include maintaining organizational processes across the group, influencing clinical program strategy, and integrating activities with other departments across the Global Research and Development organization, to help shape innovative and integrated clinical development plans. As a Disease Area leader, the Senior Director, Clinical Pharmacology will also direct Clinical Pharmacology efforts for small molecule and...

We are seeking a highly motivated and experienced Computational Chemist to join our Data and Computational Sciences Group in Boston to lead scientific innovation in physics-based molecular modeling and simulations. As a recognized expert and thought leader, you will develop the company’s physics-based computational methods platform prototype, benchmark, and implement computational methodologies, collaborate with software engineers to scale solutions across with organization, collaborate with other scientists to establish best practices, and drive global alignment to accelerate drug discovery. This is a highly visible, scientifically influential role with broad impact across multiple therapeutic areas. This is a Boston based, hybrid position...

The General Ledger Senior Accountant II conducts a range of straightforward accounting activities related to the recording, maintenance and analysis of journal entries and the general ledger under general guidance from accounting and finance managers. Key Duties and Responsibilities Collaborates with U.S. functional finance contacts to analyze and succinctly summarize monthly and quarterly fluctuations in key business accruals in the areas including but not limited to, clinical accruals, R&D accruals, manufacturing, and supply chain accruals. Prepare hedging and investment analyses and reporting deliverables Completion of month end and year end close journals for Vertex's entities as needed. Assists in the...

The Quality Systems Manager serves as a senior technical expert in the principles and application of quality assurance and compliance within a regulated environment. This role leads and supports cross-functional quality initiatives, drives continuous improvement, and ensures robust compliance across Quality Systems. The Quality Systems Manager may also lead and mentor a team to execute department and business objectives. Key Duties and Responsibilities Collaborate with internal stakeholders and external partners to resolve quality issues and deliver compliant, risk-based solutions. Identify and lead initiatives to close compliance gaps and strengthen cross-functional Quality Systems. Act as a subject matter expert and Quality...

Director, Thought Leader Liaison , US Kidney - Pove Vertex is seeking a talented leader to join our US Kidney B usiness Unit to support our aspirations of bringing p ovetacicept and inaxapli n , two Phase 3 investigational therap ies that ha ve the potential to transform multiple serious diseases , to patients . The Director, Thought Leader Liaison , US Kidney lead s thought leader engagement for both povetacicept and inaxaplin within the US Kidney Business Unit to support our launches in IgA nephropathy ( IgAN ) and APOL1 -mediated kidney disease (AMKD) . The Thought Leader Liaison...

The Manager of Quality Control will be responsible for supporting the oversight of QC external contract labs. The position will manage GMP release and stability activities in support of clinical and commercial programs, while ensuring compliance with SOP’s, policies and industry guidances. In addition, this role may support transferring/validating GMP analytical methods, establishment of internal Quality Control systems, processes and procedures in accordance with current GMP, FDA, EU, Global and ICH guidelines and regulations. This role will interact with internal cross-functional teams and Vertex network of external CMOs/contract labs to ensure that all GMP analytical methods for lot release and...

Technology Transfer Director, Technology Transfer Leader, Cell, Gene, and Biological Therapies Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people living with serious diseases, with a focus on specialty markets. We invest in diseases where there is a significant unmet need and we can have a transformative impact for patients, not just an incremental benefit. We invest the majority of our resources in research and development (R&D) to discover new medicines, because we believe the true value in our industry is unleashed through scientific innovation. Cell and genetic therapies represent two...

The Engineering & Applied Physics team at Vertex, San Diego, is looking to add a top-notch Instrumentation Software Engineer to our small, elite team of engineers and physicists. From advanced robotics and automation to microfluidics and cutting-edge microscopy, this unique in-house team develops a wide array of performance-focused technological solutions for the toughest challenges in drug discovery. Where commercial options don’t exist, the team collaborates directly with Vertex scientists to create innovative solutions that enable ground-breaking science and discovery of life-saving medicines. The Instrumentation Software & Applications Engineer plays a key role in developing control software to run our instruments...

The Executive Director of Biostatistics is a strategic, dynamic, and empowered leader, overseeing statistical functions in support of multiple company therapeutic areas or portfolios. In addition, The incumbent is responsible for the methodological and quantitative scientific contributions of their group while simultaneously driving operational excellence. The Executive Director will have a highly visible and collaborative role, partnering across various R&D functions to generate evidence in support of Vertex pipelines/products. This position is based onsite at our Boston Seaport office. Relocation assistance is available. Key Duties and Responsibilities Is responsible for leading/driving scientific statistical methodological expertise to impact the Vertex portfolio...

General/ The Protein Sciences Senior Research Scientist is an expert in purifying (mg to grams scale) and characterizing therapeutic proteins and reagents for early-stage and late-stage discovery research programs. The Senior Research Scientist is a subject matter expert in protein purification and protein analytics for cross-functional project teams. The Senior Research Scientist is seeking opportunities to improve upon existing platform processes by bringing in new technologies in automation and instrumentation along with their deep knowledge in protein purification and characterization. Key Duties & Responsibilities Operate the AKTA Avant and AKTA Explorer systems (Unicorn software) to purify antibodies, Fc fusions, and...

The Director, Regulatory Strategy will be responsible for the development and implementation of innovative global/regional regulatory strategies for assigned projects within the Vertex cell and gene therapy portfolio. This position will play a major role in shaping cohesive regulatory strategy for assigned program(s) and ensuring effective integration of broad regulatory ideas/tactics supporting program strategy. This role's assignments may be global or regional depending on the position and assigned region. This role will understand and translate regulatory, scientific, operational and business knowledge into effective implementation plans and strategy. Key Duties and Responsibilities Leads the development of regulatory strategy for assigned projects/regions...

The Engineering & Applied Physics team at Vertex, San Diego, is looking to add a top-notch Instrumentation Software Engineer to our small, elite team of engineers and physicists. From advanced robotics and automation to microfluidics and cutting-edge microscopy, this unique in-house team develops a wide array of performance-focused technological solutions for the toughest challenges in drug discovery. Where commercial options don’t exist, the team collaborates directly with Vertex scientists to create innovative solutions that enable ground-breaking science and discovery of life-saving medicines. The Principal Instrumentation Software & Application Engineer plays a lead role in defining instrument control architecture, developing control...

The Senior Director, Enterprise Applications will lead a team responsible for architecture, design, development, support, maintenance and future roadmap s for a number of strategic enterprise platforms and HR applications. These systems and technologies include ServiceNow, Workday , Vertex University , and Readcube . The Senior Director, Enterprise Applications will collaborate with senior leaders and other key stakeholders across severa l areas of the business to identify , prioritize and deliver technology solutions in support of their goals and objectives . KEY RESPONSIBILITIES Partner with business stakeholders across Human Resources and many other functional areas in order to manage and...

The Director, Manufacturing Operations Cell Therapy - Drug Substance Drug Product (DSDP) leads a team in the execution of multi-product global production of investigational cell therapy products in the Type 1 Diabetes (T1D) disease areas. The role is responsible for the compliant production of cell therapy products and the oversight and training of the manufacturing team to ensure that the company effectively and efficiently delivers therapies to patients. This role is directly responsible for leading internal manufacturing teams and working with external manufacturing on the clinical production of cell therapy products. This role will also cultivate and leverage multiple cross-functional...

The Director, Pain, Global Value & Access Strategy role will serve as Market Access Lead for the chronic indications (DPN/LSR/PNP) across our Pain portfolio, with a specific focus on suzetrigine. Based on positive Phase 2 data, Vertex is advancing into pivotal development in diabetic peripheral neuropathy (DPN) and lumbosacral radiculopathy, or LSR, which is pain caused by impairment or injury to nerve roots in the area of the lumbar spine. The individual will be responsible for leading the development of Global Market Access strategies, as well as co-lead the Global Commercial Team across the Vertex Pain portfolio. The role reports...

Vertex is hiring a Head of Access Operations and Analytics , reporting to the Vice President, US Market Access. This leader will oversee multiple teams including but not limited to Government and State Drug Transparency Price Reporting, Gross-to-Net, the US Market Access Data & Analytics Center of Excellence and Access Operations teams. This high-performing function is critical to supporting the success of patient access to Vertex medicines, informing the revenue forecast, ensuring product availability across the US and Canada, and providing data governance and access analytics in support of the Access Strategy and Access Field teams. Importantly, the leader will...