At Vertex, we are pioneering the use of large language models and generative AI to create transformative solutions across our organization. Our corporate data science team is at the forefront of that effort, and we are looking for a talented AI Product Engineer – Application to build foundations for the next generation of human augmented AI products. The ideal candidate will bring strong experience in front-end application development, full stack engineering, cloud technologies, and rigorous testing to create user-friendly interfaces. They have become well-versed in the latest Large Language Model (LLM) technologies and AI-driven solutions. You will work on a...

At Vertex, we are pioneering the use of large language models and generative AI to create transformative solutions across our organization. Our corporate data science team is at the forefront of that effort, and we are looking for a Senior AI Product Engineer – Data to build the foundations for the next generation of human augmented AI products. The ideal candidate brings strong expertise in data engineering for AI products and is well-versed in the latest Large Language Model (LLM) technologies including Retrieval-Augmented Generation (RAG) and unstructured knowledge bases. We are seeking engineers with strong experience collaborating with data scientists...

The Medical Coding Principal Analyst manages cross-functional Medical Coding tasks and oversees multiple studies varied complexity. The incumbent also oversees all vendors’ activities on assigned studies. The incumbent is recognized as a key internal resource in all areas of Medical Coding processes and systems. Key Duties and Responsibilities: Manages cross-functional Medical Coding tasks, creates and executives on cross-functional coding plans and objectives Effectively plans and manages multiple activities to meet the objectives of the coding study team Defines and manages coding project timelines on multiple complex studies Responsible for maintenance and upgrades of Medical Coding dictionaries, custom dictionary searches and...

The Medicinal Chemistry Senior Research Scientist is responsible for formidable experimental productivity and emerging creativity and versatility. The Senior Research Scientist designs and executes elaborate experiments for major research projects. Responsibilities may include the design and synthesis of small molecule targets within a project. Demonstrates resourcefulness in running multiple activities concurrently, all related to achievement of goals/ objectives. Adapts to new projects rapidly and to multiple projects effectively ensuring alignment with corporate goals. The Senior Research Scientist commands a broad perspective and a deep knowledge of related disciplines, possesses diverse project experience and a broad panorama of (relevant) literature familiarity....

Vertex Pharmaceuticals is seeking a talented leader to join our Analytical Development team in Boston, MA. As the Sr. Principal Scientist, you will play a central role in advancing transformative medicines through all stages of clinical development. You will lead a team of technical experts dedicated to small molecule and synthetic peptide/oligonucleotide analytical development activities, providing scientific leadership and fostering team development. Key Duties and Responsibilities: Lead a team of talented analytical development scientists, cultivating their growth and development. Oversee the development and validation of core analytical methods, with a focus on chromatographic techniques. Collaborate with project teams to design,...

The DTE Commercial, Marketing Technology team is playing a crucial role in enabling our commercial expansion as Vertex commercializes into new disease areas and brings more transformative medicines to patients around the world. As the Associate Director - Web Platform, you are responsible for overseeing the strategy, management and security of our organization’s web content platforms. This role focuses on ensuring the integrity, scalability, and performance of our CMS and other digital content and development platforms, while driving innovation and alignment with business objectives. The ideal candidate will have a strong background in enterprise CMS platforms, web architecture and security,...

Vertex Pharmaceuticals is seeking a talented leader to join our Analytical Development team in Boston, MA. As the Associate Director, you will play a central role in advancing transformative medicines through all stages of clinical development. You will lead a team dedicated to small molecule analytical development activities, providing scientific leadership and fostering team development. In addition, you will help develop, implement, and champion initiatives related to process improvement and scalability. Key Duties and Responsibilities: People Leadership: Lead and inspire a team of analytical development professionals, fostering their growth and development. Project Oversight: Oversee and be accountable for all analytical...

The Principal Biostatistician will perform advanced scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with some guidance and mentoring on new and complex issues. The incumbent will completed work in a resourceful, self-sufficient manner and create alternative approaches to achieve desired results. The incumbent should possess a good knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. Key Duties and Responsibilities: Conducts advanced scientific and operational statistical work for multiple clinical trials, observational studies, or real world data (RWD) investigations, including the design, development and execution of the technical/statistical infrastructure....

The Associate Director will be responsible for delivering commercial insights to inform strategic choices and commercialization decisions in the North America Cystic Fibrosis business unit. As an integral member of the North America Commercial Brand Team, and a partner to the Global Commercial Brand Team, the Associate Director will maintain a pulse on critical business questions, and formulate and execute an insights plan (involving either primary market research and/or data analytics) to answer them. Key Duties and Responsibilities: Function as a key partner to the North America Marketing lead and provide objective perspective and insights Formulate a comprehensive insights generation...

The Executive Director of Biostatistics is a strategic, dynamic, and empowered leader, overseeing statistical functions in support of multiple company therapeutic areas or portfolios. In addition, The incumbent is responsible for the methodological and quantitative scientific contributions of their group while simultaneously driving operational excellence. The Executive Director will have a highly visible and collaborative role, partnering across various R&D functions to generate evidence in support of Vertex pipelines/products. Key Duties and Responsibilities: Is responsible for leading/driving scientific statistical methodological expertise to impact the Vertex portfolio by application of both best in class and novel statistical approaches as part of...

Associate Director with extensive experience in bioanalysis for cell and gene therapies and proficient knowledge with BA-related regulatory guidance. As a member of the DMPK-Bioanalysis organization, this person will be responsible for method development/qualification of molecular and protein bioanalysis, devising scientific and regulatory strategies, managing a group of junior scientists, and preparation of high-quality reports and presentations. Key Duties and Responsibilities: Design and perform bioanalytical assay development, including quantitation of DNA/RNA and immunogenicity evaluations for cell and gene therapies Supervise junior scientists by providing scientific and technical leadership to bioanalytical assay development/qualification and analysis of study samples Evaluate novel platforms...

The Director, Pharmacology should have an outstanding record of biologics drug development, including overseeing preclinical pharmacology studies to evaluate therapeutic candidates and ensuring strategic alignment with regulatory standards to enable advancement of therapeutic candidates toward IND submission. The candidate should be viewed as an emerging authority in an area of pharmaceutical discovery and autoimmunity, with relevant experience in preclinical model design, development, conduct, and interpretation. Versatile and multidimensional, with a superior command of knowledge in most areas relevant to autoimmunity, the Director should exhibit acumen in connecting diverse activities to address complicated project needs/goals. Additionally, the Director, Pharmacology will manage...

The Clinical Development Associate Medical Director will serve as the Medical Lead for clinical trials, working with cross-functional teams on trial strategy, design, execution, and reporting. In addition to oversight and accountability for the study as a whole, this role will serve as the internal primary Medical Monitor accountable for monitoring the safety of enrolled subjects and ensuring scientific integrity. The incumbent may participate in other projects to support the clinical development program. Key Duties and Responsibilities: Participates in the development of Study Protocols, Investigator's Brochures, Clinical Development Plans and other key documents in conjunction with other line functions and...

The Clinical Development Medical Director will serve as the Medical Lead for Vertex clinical trials focusing on acute pain, working with cross-functional multidisciplinary study teams on clinical trial strategy, design and execution and serving as the Medical Monitor responsible for monitoring the safety of enrolled subjects on assigned trials. The incumbent will work on multiple trials in all Phases of clinical development and may also participate in other selected projects in clinical development. Key Duties and Responsibilities: Leads the development of Study Protocols, Investigator Brochures, Clinical Development Plans and other key study documents in conjunction with other line functions Serves...

Our Medical Writing function at Vertex is in-house, and our Writers are strategic partners in our drug development process, collaborating with cross functional teams to bring innovative new therapies to patients. This is a hybrid position which allows 2 days per week remote work and 3 days per week in our Boston Seaport office. The Medical Writing Science Manager is responsible for preparing moderately complex clinical and regulatory documents and represents Medical Writing Science as a cross-functional team member at clinical study level activities. This role contributes scientific knowledge and analytical skills to the development of clinical regulatory documentation,...

The Icertis Technical Lead will define the technology strategy and drive the delivery and support of the Contract Lifecycle Management (CLM) platform and related solutions. This role will partner with business stakeholders to deliver capabilities and execute on the platform roadmap that aligns with the business strategy. Additionally, the Icertis Technical Lead will maintain reliability, scalability, and compliance of the platform while providing opportunities for developing and implementing innovative solutions and integrations to meet the business needs. Key Duties and Responsibilities: Become a trusted partner by understanding the business needs and vision to deliver technology solutions to enable the business...

Are you adept managing and developing complex financial solutions in partnership with Finance & Accounting? Our DTE Enterprise Technology team is seeking an experienced functional lead analyst with solid technical knowledge, a real passion for addressing business needs using data and technology and strong collaboration capabilities. You will build, support, and develop solutions in our Enterprise Planning & Reporting environment to support Finance, Accounting, and enterprise level efforts. You will partner with colleagues across the DTE organization, external partners, and software vendors with a focus on our financial business systems and processes. You’ll need to be a self-starter with a...

The Cyber Threat Operations (CTOps) analyst is responsible for managing activities relating to monitoring and responding to security events. Additionally, this position is responsible for the development and oversight of the Cyber Security Incident Response Team (CSIRT) program. The CTOps Analyst works with multiple technology platforms and interfaces with other groups within IT security operations, IT security architecture, any offshore partners, and other technology and business functions. The scope of duties for the CTOps Analyst’s organization includes overseeing: CSOC, Global CSIRT, SOAR & SIEM, Forensics and Threat Hunt. Key Duties and Responsibilities: ​ Contribute to the company information and digital...