Vertex Job Trends

The Portfolio & Program Management Senior Manager is a global role within the Program and Portfolio Management (PPM) organization. The incumbent is responsible for delivering cross-functional project management excellence to programs across the drug development lifecycle (Research, Pre-clinical and Clinical Development, Registration and Commercialization). The incumbent is expected to apply project management best practices to solve complex problems and facilitate the execution of integrated project plans and deliverables for cross-functional drug development teams and portfolio operations initiatives. Key Duties and Responsibilities Oversee integrated project planning processes for one or more teams including scheduling, risk management, communication plans and reporting Provide...

The Health Economics & Outcomes Research Senior Manager will participate in the development and execution of Health economics and outcomes research studies in support of Vertex's products. Key Duties and Responsibilities Executes HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value Provides best practices insights into the design of Vertex observational research studies Executes key HEOR pre-launch/launch deliverables Develops presentations to communicate complex HEOR evidence Acts as a resource for team members...

Job Posting Vertex Fellows Program Location San Diego, CA Flex Designation On-Site Designated Start Date August/September 2026 Application Deadline January 9, 2026, by 500 PM ET Please submit a CV/resume and cover letter with your application. Letters of Recommendation will be requested if invited to interview. About the Program The Vertex Fellowship is a unique, one-year training program for outstanding scientists and physicians passionate about solving unmet medical needs and advancing transformative science. Fellows join Vertex for a customized post-doctoral experience, gaining hands-on experience with real-world R&D challenges and benefiting from mentorship by Vertex leaders. This program is designed to...

Job Posting Vertex Fellows Program Location Boston, MA Flex Designation On-Site Designated Start Date August/September 2026 Application Deadline January 9, 2026, by 500 PM ET Please submit a CV/resume and cover letter with your application. Letters of Recommendation will be requested if invited to interview. About the Program The Vertex Fellowship is a unique, one-year training program for outstanding scientists and physicians passionate about solving unmet medical needs and advancing transformative science. Fellows join Vertex for a customized post-doctoral experience, gaining hands-on experience with real-world R&D challenges and benefiting from mentorship by Vertex leaders. This program is designed to provide...

About the Program The Vertex Physician Investigator (VPI) Program is a full-time, immersive opportunity for exceptional early-career physician-scientists who are passionate about solving unmet medical needs and advancing transformative science. Over two years, participants will complete four customized six-month rotations, receive intensive training, and benefit from direct mentorship by Vertex senior leaders. This program is designed to provide a broad understanding of the drug development process and prepare participants for future leadership roles in biotechnology. Program Highlights Four Rotations Over Two Years Two mandatory rotations Drug Discovery and Clinical Development Two elective rotations in other Vertex functions of the participant’s...

Vertex is seeking a strategic and collaborative Senior Director, Finance Technology to drive innovation and transformation across Financial Systems, with a focus on Tax, Treasury, and Accounting. This role sits within the Data, Technology & Engineering (DTE) organization and serves as a trusted partner to the CFO organization, aligning technology solutions with business strategies to deliver impactful outcomes. The ideal candidate will bring deep expertise in financial systems, strong stakeholder engagement capabilities, and a passion for enabling change through technology and AI. You will also be close to the technology and have the ability to lead from a technical first...

The Senior Director, HR Technology and Digital Innovation leads the strategic transformation of HR technologies and HR data platforms at Vertex. This role is responsible for architecting and executing a forward-looking digital roadmap that integrates AI, automation, and analytics to enhance employee experience, operational efficiency, and data-driven decision-making across the HR function. This role will lead a team responsible for architecture, design, development, support and future roadmaps for HR applications. These systems include as examples Workday, Cornerstone , GoodTime or a new Digital Assistant . The Senior Director, HR Technology and Digital Innovation will collaborate with senior leaders and other...

Vertex is seeking a high-impact , strategic recruiter to join our Talent Acquisition team as an Associate Director supporting senior hiring across Finance, Accounting, and Legal. This role offers broad visibility across senior leadership and requires exceptional business fluency, executive presence, and relationship management . The ideal candidate brings deep executive search expertise and functional knowledge of Finance, Accounting and/or Legal , enabling them to understand the talent landscape, leverage existing networks, and deliver business-aligned hiring strategies in a fast-paced, matrixed environment. This candidate is a bold, business-minded talent advisor who is passionate about building teams that drive excellence. The...

The Director, Thought Leader Liaison Lead, US Kidney leads thought leader engagement for both povetacicept and inaxaplin within the US Kidney Business Unit to support our launches in IgA nephropathy (IgAN) and APOL1-mediated kidney disease (AMKD). They will act as the lead for the development of cross-functional Thought Leader engagement plans, regional insights meetings, regional conferences and will bring back field insights that will inform the development and evolution of the marketing strategy. We are seeking a candidate that has a strong track record in US commercial roles and the ability to thrive in a fast-paced, innovation-focused environment. This role...

Job Posting Description As the Associate Director of Strategic Sourcing, you will be a part of a fast-growing and innovative organization at the company’s world headquarters in Boston, MA. The department is committed to a trusting and collaborative culture where we value growth and development. We engage proactively with our stakeholders to truly understand their needs and deliver results for our company and for patients. If you are looking for an entrepreneurial, hands-on, team-oriented environment where you can have a big impact, then this is the right place for you! This role is responsible for leading category management activities for...

General/ The Expense Manager will deliver auditing and operational support to the Global Expense & Card Program Team. This role will oversee the Concur Detect by Oversight technology, build expense report auditing strategies, and provide support to employees related to expense reports. The ideal candidate demonstrates a proficient level knowledge of Concur and a critical thinking & detail-oriented mindset. The role demands a proven ability to provide expense guidance & support to end-users and the ability to audit expenses against policy. Strong communication, judgment, collaboration, customer service, and stakeholder management are critical. Key Duties & Responsibilities Define expense auditing strategy...

The individual in this position will provide strategic and solutions-oriented advice to a broad spectrum of internal clients on worldwide regulatory issues related to the processing of personal data, including but not limited to the US State Privacy Laws, Section 5 of the FTC Act, CAN-SPAM, EU General Data Protection Regulation (GDPR), and Canadian privacy laws. The role will also support the maturation of privacy-related policies, notices, and SOPs, supporting the strategic direction for the global privacy program and related processes and training. Key Duties and Responsibilities Performing regular privacy assessments of new and existing business processes (including through data...

Vertex is in an exciting time of growth and innovation, and technology and data are valued as strategic assets for the organization. The North America Commercial Operations CRM Field Operations Team is looking for a CRM Field Operations Lead to ensure continued customer centricity and success. The CRM Field Operations Lead plays a critical role between the cross-section of sales and marketing and a close partnership with other business functions. The primary responsibility of this position will be to support designated BU HQ and Field teams with the continuous improvement of the customer relationship management (CRM) system. The Senior Manager,...

Vertex is seeking experienced and talented commercial leaders to join our US Pain Business Unit to support our journey to bring forth new options for the treatment of pain. The Territory Account Manager will be responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to generate advocacy and drive sales growth for the US Pain Business Unit, which is preparing for potential commercialization of an investigational novel selective inhibitor of NaV1.8 in acute pain. We are looking for candidates with a strong track record of delivering exceptional results with patient focus, developing...

Vertex is seeking an experienced Regulatory Affairs Advertising & Promotion Director to provide strategic and tactical regulatory direction for the review and approval of product, pipeline, and disease state communications for its pain assets in the US. This role is critical in ensuring that all promotional and nonpromotional communications meet regulatory requirements and support Vertex’s business objectives. The Director will collaborate cross-functionally to develop viable communications and implement processes that drive compliance and business success. Key Duties and Responsibilities Serve as a regulatory expert on US statute, regulations, and relevant guidance governing product promotion and related communications, including pipeline and...

The Director , Order Management Operations - Heme develops and provides strategic direction and leads daily operations of the US care management team supporting the US, Heme Business Unit . This individual will represent the US on the global cross-functional manufacturing team, developing slot allocation policies, managing exceptions processes, and managing system/manufacturing capacit y. This individual will also play a key role in ensuring exceptional support is provided to our customers by our care manger team. This critical role will be highly cross functional within Vertex with the goal of providing industry-leading patient support through patient facing interactions and logistical...

General position summary The R&D Quality Assurance (RDQA) Director, as part of the Analytics and Centers of Excellence (ACE) vertical, is responsible for providing leadership, management, operational oversight and effective delivery of both large- and small-scale ACE initiatives in support of all verticals within RDQA and other related Vertex Quality organizations. These initiatives are focused on building a robust process / data rich landscape that empowers teams through standards and a data-driven decision-making culture as well as integrating and standardizing operations, processes, information, data, and technology to advance and align the capabilities, competencies, and outputs with high value goals /...

The Senior Medical Science Liaison (Sr MSL) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights, and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources, and provide the...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Corporate Finance Senior Manager is a key member of Vertex’s Finance organization, supporting the annual budgeting and monthly forecast processes including the analysis, preparation, and communication of headcount and compensation and benefits results to the Finance Leadership Team. The role will collaborate closely across Finance, HRBPs, HR Total Rewards and other teams to identify and deliver actionable insights that drive performance, maintain fit-for-purpose reporting as the business evolves, and advance enterprise initiatives to scale corporate planning processes. The ideal candidate will be an excellent communicator, with the ability to simplify complexity, maintain strong attention to detail and influence decision-making...

The Quality Specialist will provide QA support for manufacturing operations, analytical laboratory operations, and materials management for the internal programs at Vertex Manufacturing Center (VMC), Boston, MA. The position will be a part of the QA operation floor support team. This role will review & support activities related to product disposition, including batch data, batch records, deviations, in-process data, EM data, QC release testing, and other quality systems documentation. The Quality Specialist supports or executes daily activities related to equipment or instrumentation supporting Facilities, Utilities, Manufacturing, and Labs. The position will support multiple production functions (from Quality operations to Quality...

The Senior Manager, Strategic Sourcing IT & Telecom will lead category management activities, including the development and execution of sourcing strategies for IT and telecommunications spend areas. This role involves Strategy creation and implementation, RFx development, competitive bid analysis, contract negotiation, and strategic supplier management. The individual will collaborate closely with business partners to align sourcing initiatives with organizational priorities and optimize internal processes to enhance efficiency and cost-effectiveness. Key Duties and Responsibilities Lead category management for IT and telecom areas including specifically hardware and telecom, including sourcing strategy development and supplier performance management. Utilize e-sourcing tools to support sourcing...

Vertex currently operates at the forefront of rare disease scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Sickle Cell Disease, Transfusion-Dependent Beta Thalassemia and Acute Pain. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Diabetic Peripheral Neuropathy, Type 1 Diabetes, IgA Nephropathy (IgAN), APOL-1 Mediated Kidney Disease, and Muscular Dystrophy, among others. The Director, Channel Distribution Strategy is accountable for the design, implementation and evolution of channel distribution strategies across the organization’s...

The Director, Global Process Excellence, Finance Systems and Reporting is a key member of the Vertex Global Finance organization and will be leading continuous improvement workstreams including projects aimed at improvement of Global Finance processes, implementation and enhancement of finance systems and support of enterprise reporting capabilities. Reporting to the VP, Global Process Excellence, Finance Systems and Reporting, this role is a key leader in ensuring that Vertex’s global R&D/BSMO finance teams can scale efficiently to meet the needs of an increasingly large and complex pipeline by optimizing global processes, implementing and enhancing finance systems and building new scalable global...

Vertex is seeking to hire a Senior Manager, Data Enablement, Infrastructure and Reporting for Pain Therapeutic Area, within the U.S. Market Access (USMA) department, who will be a key contributor in the Data & Analytics (D&A) Center of Excellence (COE) team. The role requires strong data and analytics experience as well as deep subject matter expertise of value & access strategies, with an in-depth understanding of U.S. pricing and reimbursement dynamics. This individual will contribute to the generation of market access specific insights that impact patient access to Vertex inline brands and pipeline therapies by informing market access strategy, as...

Vertex is seeking a talented individual to join our process chemistry group in San Diego, CA. This role will support drug substance development programs at Vertex performing synthetic organic chemistry in the laboratory at a high level to design and execute syntheses of challenging compounds, troubleshoot a diverse range of chemistry issues and devise corrective solutions, and analyze complex data sets that lead to clear conclusion or recommendations to guide the synthetic decision. In addition, the individual is expected to work both independently and in a matrix team environment. Key Duties and Responsibilities Designs, executes, and interprets synthetic organic experiments...

The Medical Writing Science Manager is responsible for preparing moderately complex clinical and regulatory documents and represents Medical Writing Science as a cross-functional team member at clinical study level activities. This role contributes scientific knowledge and analytical skills to the development of clinical regulatory documentation, under minimal supervision. Key Duties and Responsibilities Authors moderately complex clinical regulatory documents (e.g., including clinical study protocols, clinical study reports, investigator’s brochures, and sections of regulatory submissions) in partnership with key cross-functional stakeholders Serves as the lead Medical Writing Scientist for moderately complex clinical studies Supports Medical Lead with review and interpretation of clinical...

Vertex Pharmaceuticals is seeking an Associate Director (AD) of Kidney Field Training & Development to join the North America Commercial Field Training (NACFT) organization. Reporting to the Director, North America Commercial Field Training – Kidney, this individual will play a critical role in preparing our field organization for launch excellence across Vertex’s Kidney portfolio. The AD will partner closely with cross-functional Kidney BU leaders in Marketing, Medical Affairs, Market Access, and Field Leadership to design, deliver, and continuously evolve learning solutions that build deep scientific fluency, confident messaging, and customer engagement excellence across our field and field leadership teams. Key...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through data, and technology innovation – with AI at the core of our transformation strategy. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. The Senior Director, CMC and Manufacturing Data & Technology will define, lead and execute the...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through data, and technology innovation – with AI at the core of our transformation strategy. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. The Senior Director, Supply Chain Data & Technology will define, lead and execute the vision for...

The Business Engagement & Technology Principal Analyst will be a technical resource in ensuring delivery and support of commercial-off-the-shelf (COTS) and a wide range of custom solutions in support of their business partners. The Business Engagement & Technology Principal Analyst will partner with business leadership to deliver capabilities and execute on a roadmap that align to support business strategy in Clinical Operations and Medical Writing . Additionally, the Business Engagement & Technology Principal Analyst will maintain reliable, scalable and compliant systems that easily meet business needs by efficient delivery and enhancements that provides opportunities for developing and implementing innovative solutions...

Vertex is seeking to hire an Associate Director, NA Pain Market Research to join the North America Forecasting, Analytics and Insights team. The Associate Director will be responsible for overseeing and delivering commercial insights to inform strategic choices and commercialization decisions for the Pain business unit (BU). Market research workstreams will span functions within the BU including Marketing, Field, and Patient Support. The Associate Director will work alongside the Director of NA Pain Market Research to provide integral support primarily for the US Pain BU and Patient Support team. This person will maintain a pulse on critical business questions and...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Please note Experience within Montana is essential for this role. The Pain Territory Account Manager is responsible for plan execution, delivering sales performance, and product promotion in Montana. (Territory may change upon the needs of the organization). The PTAM must maintain a high level of knowledge within the disease states and product labeling. Activities include disease state and product education to referring HCPs, collaboration with internal and external stakeholders, and shaping and executing sales strategies. The individual in this role must be goal-oriented and accountable for their individual performance, while acting in a professional and compliant manner. This role will...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...