Vertex Job Trends

The Clinical Development Associate Medical Director will serve as the Medical Lead for clinical trials, working with cross-functional teams on trial strategy, design, execution, and reporting. In addition to oversight and accountability for the study as a whole, this role will serve as the internal primary Medical Monitor accountable for monitoring the safety of enrolled subjects and ensuring scientific integrity. The incumbent may participate in other projects to support the clinical development program. Key Duties and Responsibilities Participates in the development of Study Protocols, Investigator's Brochures, Clinical Development Plans and other key documents in conjunction with other line functions and...

The main responsibility of the Commercial Strategy Associate Director is to developing and implementing the commercial strategy for assigned therapeutic areas within scope of role working with their leadership team. This person is accountable for understanding the market landscape and Vertex's position within the market and all business activities aligned with performance goals of the portfolio and tracking performance against those goals, also ensuring identification, activation and onboarding of new business lines, and ongoing engagement to ensure healthcare professionals and patient experiences are seamless throughout the treatment journey. Key Duties and Responsibilities Developing and implementing commercial strategy for therapeutic areas,...

The Field Communication Engagement Senior Manager develops and executes clear, comprehensive communication plans that inform, engage, and activate field teams and key stakeholders. This role supports the VP of Strategic Customer Engagement and field sales leaders by driving engagement, supporting pipeline launches, and strengthening collaboration across the kidney field team. Key Duties and Responsibilities Create high-impact communication and messaging to support kidney field business goals. Proactively identify opportunities for communication optimization through regular field rides, team observations, and performance analysis to enhance field efficiency and effectiveness. Work with cross-functional partners to identify, build, and maintain best internal channels to drive...

The Medical Science Liaison (MSL), with support and guidance from peers and management, will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex’s compounds in a timely, ethical and stakeholder-focused manner. The MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the design and execution of the Medical Affairs strategy and plan. The MSL will engage HCPs in response to scientific educational and research needs with available Vertex...

We are seeking a strategic, analytically rigorous, and innovative MBA summer associate to help measure and increase the impact of Medical Affairs. The intern will lead measurement and KPI establishment of Medical-led activities such as publications, congress presence, digital education, and field medical education, using advanced analytics and AI to generate actionable insights and inform decisions. This role is designed for a candidate who can combine business judgment with hands-on quantitative analysis, translate ambiguous questions into analytical approaches, and communicate findings to senior leaders and non-technical audiences. The Medical Information, Technology and Innovation (MITI) group is responsible for leading the...

Company Overview Vertex is a global biotechnology company focused on investing in scientific innovation to create transformative medicines for people with serious diseases. Across our organization, we work with urgency, rigor, and collaboration to deliver therapies that improve patient outcomes and create long-term value. The Operational Excellence & Business Analytics team serves as the process improvement and performance enablement backbone of CMTO, providing the integrated performance visibility, standardized metrics, and improvement discipline required to run, grow, and optimize Vertex's external commercial manufacturing network. The Associate Director, Operational Excellence & Business Analytics is an end-to-end role that combines capabilities into...

The Chemistry Manufacturing Controls Associate Director executes multi-product global regulatory CMC strategies for investigational and marketed products. This role leads the preparation and filing of regulatory CMC submissions and manages the interactions with Health Authorities for CMC topics. This role also provides regulatory guidance to various cross-functional teams and ensures all applicable global regulatory requirements are considered and appropriately incorporated into investigational and commercial products. This role may supervise other regulatory staff. Key Duties and Responsibilities Leads the preparation and review of CMC sections of regulatory submissions, as well as the interactions and responses with regulatory agencies Develops global CMC...

The Medical Information, Technology and Innovation (MITI) group is responsible for leading the technological advancement and innovation for Vertex’s Medical Affairs teams. MITI enables and advances internal capabilities and efficiency, and external excellence in how we interact with our HCPs in support of our medicines. We are seeking a strategic and innovative MBA Intern to support the transformation of Medical Affairs business processes. This role will be instrumental in designing and implementing systems, processes and technologies – including AI driven solutions that enhance quality, effectiveness, and efficiency – to ultimately increase the impact of medical insights and scientific exchange...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex Pharmaceuticals is seeking a highly motivated Packaging and Labeling Manager to support its growing commercial portfolio and robust pipeline of development-stage products. This role is responsible for managing end-to-end pharmaceutical artwork development and implementation activities, ensuring packaging and labeling materials are developed, reviewed, approved, and implemented accurately and on schedule. The Packaging and Labeling Manager will collaborate extensively with cross-functional stakeholders, including Regulatory Labeling, Quality Assurance, Supply Chain, Manufacturing Science & Technology (MS&T), external graphics providers, and packaging sites worldwide. The ideal candidate is a collaborative leader with strong project management skills, extensive knowledge of pharmaceutical artwork processes, and...

The territory will cover major cities in Greenville and Columbia, South Carolina including Spartanburg, Rock Hill, and Anderson, among other surrounding local towns. The candidate is preferred to live within the surrounding territory. The Kidney Territory Account Manager (KTAM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs), developing a strategic business plan, communicating thorough disease and product knowledge to HCPs and centers of care. This role must understand market dynamics in rare, complex disease states, demonstrate excellent judgment, and be motivated by the desire to improve patients' lives. The KTAM will report into a Regional Field...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Toxicology Senior Research Fellow acts as the Preclinical Safety Assessment (PSA) lead on Research project teams, cross-site teams and steering committees and is accountable for overall project and often disease area and/or site strategy supporting safety assessment of novel molecules and therapies advancing through the Vertex discovery pipeline into early development. The key scientific individual contributor functions as part of cross-functional project teams and designs appropriate safety in vivo and in vitro safety studies to support advancement of project compounds/therapies to the candidate nomination stage. The incumbent is also accountable for site safety strategy and plays an integrated role...

The Director, Biostatistics will independently perform highly scientific statistical functions in support of the company’s Global Medicines Development and Affairs (GMDA) area on new and complex issues. The incumbent will complete work in a resourceful, self-sufficient manner and create alternative approaches to achieve desired results if needed. In addition, the Director provides independent strategic and technical contributions. The incumbent possess an excellent knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. As a people manager within the organization, has financial accountabilities and human resource responsibilities for assigned staff. Key Duties and Responsibilities Directs one or more...

Role Summary The Executive Director of Performance Excellence & Business Transformation for Global Clinical Operations is a senior strategic leader responsible for driving operational excellence, innovation, and transformation across Vertex’s global clinical trial portfolio with a strong focus on technology innovation. This role leads end‑to‑end clinical trials process optimization, oversees global transformation programs, advances digital capabilities (i.e., Clinical Technology Innovations and transformative AI/ML strategies); leads Business Intelligence and Analytics, develops and implements the strategy for workforce planning and resource utilization and embeds a high‑performance culture that accelerates study delivery while ensuring regulatory compliance and patient safety. This role reports to...

We are seeking a highly motivated Research Scientist, Analytical Development – Functional Genomics & Multi-omics to develop, optimize, qualify, and implement sequencing-based analytical methods supporting pluripotent stem cell (PSC) bank characterization, process development, and biomarker translation. This role will combine strong wet-laboratory expertise in nucleic acid preparation, stem cell culture, and sequencing library construction with bioinformatics capabilities for analysis and integration of transcriptomic and epigenomic datasets. The Research Scientist will establish fit-for-purpose workflows spanning transcriptomic and epigenomic methods for multi-omic analysis. A central responsibility will be translating high-dimensional sequencing findings into robust, practical targeted assays—including RT-qPCR and ChIP-qPCR methods—that can...

The Associate Director will be responsible for delivering commercial insights to inform strategic choices and commercial decisions in hemoglobinopathies (SCD/TDT) and other categories. As an integral member of the commercial strategy team and extended brand team, the Associate Director will maintain a pulse on critical business questions to formulate and execute an insights plan (involving either primary market research or data analytics) to answer them. This is a hybrid/on-site role based in Boston, MA (3 days onsite, 2 days remote on a weekly basis). Key Duties and Responsibilities Function as a key partner and provide objective perspective and insights to...

Vertex is seeking an Supply Change Analytics & Insights Manager to join the Supply Chain Operations, Resilience, and Efficiency (SCORE) team. This role will partner with supply chain stakeholders across all disease areas to understand reporting needs, define meaningful metrics, and deliver scalable reports and dashboards that support effective decision-making and improve business performance. The individual will work cross-functionally with Finance, ExM, Quality, DTE (Data & Tech), BAR, and other business partners to align on KPIs, reporting definitions, data sources, and analytics priorities. KEY RESPONSIBILITIES Lead supply chain reporting and analytics initiatives from requirements gathering through implementation, adoption, and continuous...

The DMD Biology team at Vertex Cell and Genetics Therapy Research (VCGT Research) is seeking a highly experienced and motivated Principal Research Associate to build genetic therapy candidates and to develop and execute assays to support advancing non-viral therapeutics through program stage gates. The successful candidate will bring strong hands-on expertise in molecular biology, cell biology, gene-expression analysis, and protein-based assays. This individual will work closely with cross-functional partners to generate high-quality data that informs discovery-stage decisions and candidate progression. This laboratory-based role will design, execute, optimize, and interpret molecular and cellular assays that characterize functional delivery, intracellular activity, gene...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex is seeking a hands-on Azure DevOps Engineer to build, automate, secure, and support Azure cloud platforms used by enterprise applications, data solutions, and AI-enabled capabilities. This is an individual-contributor role for an engineer who enjoys developing practical solutions, improving delivery pipelines, and resolving complex technical issues. Working with software engineers, cloud architects, Information Security, and business stakeholders, this individual will implement DevSecOps practices, infrastructure as code, cloud automation, and reliable software delivery patterns. The ideal candidate combines strong Azure engineering skills, a security-focused mindset, and the ability to work independently in a collaborative environment. Key Duties and Responsibilities Build,...

The Project Management Associate Director role is an exciting opportunity to lead transformational projects that will streamline Supply Chain processes by leveraging digitization and AI. The incumbent will be responsible for the integration, creation and execution of multiple complex project and program plans. By partnering closely with leadership, SMEs and cross-functional team members, the incumbent will develop and maintain fully integrated project plans to ensure that deliverables are successfully executed, are in accordance with project objectives, and are within budget. The incumbent is also responsible for comprehensive communication with leadership and across functions, including status reporting, risk management and escalation...

General position summary Biomarker Operational Quality Associate director provides Biomarker quality leadership and oversight across GxPs-related to research and development, implementation into clinical trials and potential commercialization of clinical biomarkers into IVDs. The incumbent will collaborate with business partners and GCP Operational Quality to drive quality outcomes and operational excellence, through supporting operational management oversight for these areas. The Associate Director will ensure that quality oversight activities maximize value, impact and delivery in assuring compliance, excellence in quality and readiness for future needs. The Associate director, Biomarkers Operational Quality will also collaborate with the Biomarker Operations team to review and...

The Early Development Associate Medical Director will serve as the Medical Lead for Phase 1 clinical trials, working with cross-functional teams on trial strategy, design, execution, and reporting. In addition to oversight and accountability for the study as a whole, this role will serve as the internal primary Medical Monitor accountable for monitoring the safety of enrolled subjects and ensuring scientific integrity. The incumbent may participate in other projects to support the clinical development program. Key Duties and Responsibilities Participates in the development of Study Protocols, Investigator's Brochures, Early Development Plans and other key documents in conjunction with other line...

Vertex is seeking a Commercial Training, Senior Manager to enhance the skills, capabilities, and knowledge of customer-facing teams supporting reimbursement and patient access. This role is responsible for developing, implementing, and facilitating impactful training programs that support field readiness, onboarding, and ongoing capability development for field reimbursement and patient support audiences. The ideal candidate brings strong expertise in reimbursement, access, training strategy, and adult learning, with the ability to translate complex concepts into practical, field-relevant learning experiences. Work Model On-site or Hybrid Key Responsibilities Partner with cross-functional stakeholders to identify training needs and recommend learning solutions for field reimbursement teams...

The Associate Director, Commercial Data Governance will lead the management and continuous improvement of data governance capabilities across Vertex’s commercial organization. This role will establish standards, policies, processes, and accountability frameworks that improve quality, consistency, accessibility, security, and responsible use of commercial data. Key Responsibilities Lead the commercial data governance strategy, roadmap, and operating model in alignment with enterprise data governance priorities and commercial business objectives. Define and maintain data governance policies, standards, procedures, and controls for commercial data domains. Establish clear data ownership, stewardship, and accountability across commercial data assets. Partner with data owners and business stakeholders to define...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Vertex is seeking a strategic and collaborative marketing professional to join our US Kidney Business Unit to support our aspirations of bringing Povetacicept to patients, a Phase 3 investigational therapy that has the potential to transform lives across multiple serious diseases. The Senior Marketing Manager, US Kidney - Pove will lead the strategic execution for the HCP marketing team alongside The US Kidney marketing team, which is preparing for potential commercialization of an investigational therapeutic being studied for the treatment of Immunoglobulin A nephropathy (IgAN) and other B cell-mediated diseases. This individual will lead the development and execution of marketing...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

The Manager of Commercial Rebate Operations has a critical role, reporting into the Associate Director, Rebate Operations team within the US Market Access organization. This is an exciting opportunity for a subject matter expert that applies an enterprise-level mindset and technical expertise at the intersection of data, process optimization, automation and innovation. The ideal candidate is passionate about patients, focused on driving for results, and is willing to be involved in hands-on execution while building new functional capabilities. The successful individual must be adept at cross-functional collaboration, while also having a high degree of attention to detail and accuracy to...

The Senior Regional Sales Director, West Region is accountable for achieving business targets and creating a high-performance culture by leading and developing a team of sales professionals for Vertex’s flagship Cystic Fibrosis Business Unit. This is a high impact highly visible first-line sales leader role accountable for a blockbuster portfolio and a member of the Business Unit Leadership Team. This role reports directly to the Vice President & General Manager of the Business Unit and leads a team of ~7 highly seasoned sales account professionals. Paramount to success in this role is the ability to collaborate cross-functionally with customer-facing and...

Vertex is seeking a Senior Principal Research Scientist, Medicinal Chemistry to provide scientific leadership in the design and optimization of small-molecule therapeutics across discovery programs. Leading from the lab, this role will play a critical part in advancing high-quality drug candidates from early discovery through candidate selection, while partnering across multidisciplinary teams to solve complex scientific challenges. The ideal candidate is an accomplished medicinal chemist with deep expertise in small-molecule drug discovery, a strong record of scientific innovation, and demonstrated success in a fast-paced and matrixed research environment. This is an on-site role with approximately 75% of time being spent...

Vertex is seeking a Director, Medicinal Chemistry to provide people management and strategic leadership for small-molecule discovery programs and to help advance compounds from early discovery through candidate selection. This role is responsible for defining and executing medicinal chemistry strategy, leading compound design and optimization, and advancing programs through close partnership with cross-functional teams. The successful candidate will manage a team and bring deep scientific expertise, strong leadership capabilities, and a proven track record of advancing discovery-stage programs in a fast-paced research environment. This is an on-site role with an approximate 50% lab time commitment. Key Responsibilities Lead medicinal chemistry...

The (Market Access) Operations and Analytics Associate Director leads sophisticated analyses, develops financial models, and generates insights to address strategic market access questions, presenting findings effectively and succinctly to leadership. The role requires the extraction and synthesis of relevant data to deliver timely insights into the underlying factors driving forecasts and variances to plan, while delivering forward-looking perspectives that inform and drive key business decisions— supporting both approved and potential future indications Key Duties and Responsibilities Work independently to surface insights from internal data sets and secondary sources that answer key business questions and inform access and commercial decisions Play...

Vertex San Diego Drug Metabolism and Pharmacokinetics (DMPK) team is seeking a highly motivated, experienced scientist and leader at the Senior Director level to help advance discovery and development of transformational therapies for serious unmet medical needs. The Senior Director will be part of the local site DMPK leadership team. This role's responsibilities include developing and maintaining optimal organization within DMPK, as well as the scientific and managerial coordination of its groups and personnel. This role will optimize interdisciplinary activities within DMPK and integrate activities with those of the other sites and departments and thus play a major role in...

The Director, Innovation and Business Transformation leads the execution across multiple highly complex and interconnected technology-enabled transformation initiatives within Medical Writing Science (MWS). The role translates established transformation priorities into a coordinated slate of initiatives, integrates business, solution, implementation, and adoption approaches, and aligns MWS leaders with enterprise technology partners. The Director manages cross-initiative dependencies, risks, resources, and trade-offs to ensure initiatives progress through the established transformation lifecycle and deliver sustainable business outcomes. Key Duties and Responsibilities Translate MWS transformation priorities into a coordinated slate of executable initiatives with clear outcomes, sequencing, resource requirements, decision pathways, and success measures. Direct...

The Senior Manager, Innovation and Business Transformation drives the execution of defined technology-enabled transformation initiatives across Medical Writing Science (MWS). The role assesses business needs and workflows, translates requirements into practical implementation plans, coordinates testing and implementation activities, and enables successful adoption and continuous improvement of new capabilities. Working closely with MWS leaders, users, and enterprise technology partners, the Senior Manager ensures solutions address established business needs, are effectively implemented, and improve scientific and operational ways of working. Key Duties and Responsibilities Execute defined technology-enabled transformation initiatives, coordinating activities, milestones, stakeholders, and deliverables to achieve established business outcomes. Assess current-state...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that...

Company Overview Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. We are driven by a commitment to patients, scientific excellence, and an inclusive culture where talented people can do their best work. Our teams collaborate across disciplines to translate data, insights, and technology into meaningful business outcomes and improved patient experiences. Role Summary The Director, Commercial Data Strategy & Enablement will lead the strategy, governance, and enablement of commercial data assets, platforms, and capabilities across the organization. This role will partner closely with Commercial, Digital & Technology, Data...

The Associate Director, Innovation and Business Transformation leads complex technology-enabled transformation initiatives across Medical Writing Science (MWS), translating prioritized business needs into well-defined, executable solutions. The role leads workflow analysis and redesign, defines business requirements and success measures, evaluates solution approaches, and partners with MWS leaders and enterprise technology teams to advance initiatives from concept and experimentation through implementation, adoption, and optimization. The Associate Director navigates ambiguity and complex dependencies, facilitates business decisions, and ensures solutions address defined business needs and deliver measurable outcomes. Key Duties and Responsibilities Lead individual complex transformation initiatives from prioritized business need through solution definition,...

Vertex is seeking a talented strategic colleague to serve in a critical role supporting the Disease Strategy Team Program Office in the Office of the CEO. The Strategy & Operations Director will partner closely with a Disease Area Executive (DAE) to drive special initiatives to support a particular DST. We are seeking a candidate that has a strong track record in strategic roles, along with cross functional collaboration and effective communication skills to apply for this opportunity. Key Duties and Responsibilities Partners with DAE to lead strategic projects and high-profile initiatives Act as a liaison between cross functional...

The Engineering and Applied Physics team at Vertex, San Diego, is looking to add a top-notch Senior Mechanical Engineer II to our elite team of engineers and physicists. From advanced robotics and automation to microfluidics and cutting-edge microscopy, this unique in-house team develops a wide array of performance-focused technological solutions for the toughest challenges in drug discovery. Where commercial options don’t exist, the team collaborates directly with Vertex scientists to create innovative solutions that enable ground-breaking science and discovery of life-saving medicines. The Senior Mechanical Engineer II plays a key role, helping us translate ideas into design, design into hardware,...

The Associate Director of Logistics Operations is responsible for management and execution of all Small Molecule & Biologics product distribution and product movement logistics in support of product delivery. This includes establishing, championing, and implementing end to end management of clinical/development and commercial shipments with real-time tracking and troubleshooting of issues. This person will manage Temperature Controlled logistics shipments, 3PL management, carrier management, import/export compliance and product distribution. The role works closely with couriers, Clinical Operations, CMO scheduling staff, QA and other stakeholders to plan and execute product movement logistics. The Associate Director is integral to the success of the...

The Senior Director, US Patient Support Programs (PSP), Affordability Programs will provide strategic and operational leadership for affordability programs designed to help eligible patients access Vertex therapies. This role will lead the development, implementation, oversight, and continuous improvement of patient affordability offerings, including copay assistance, patient assistance programs (PAP/free drug), Bridge, Quick Start, and other access-support programs. This leader will establish a scalable operating model for affordability programs; build and develop a high-performing team; and ensure programs are delivered with a consistent focus on patient experience, operational excellence, appropriate governance, and compliance. The Senior Director will work closely with cross-functional...

The South Florida Territory includes Miami, Naples, Sarasota, Port St Lucie, and Fort Lauderdale areas. The candidate is preferred to reside in the areas of the territory, ideally, Miami, West Palm Beach, or Fort Lauderdale. The Regional Field Leader, Associate Director will be responsible for the oversight of one region in the US Pain Business Unit and will be responsible for the commercialization of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. We are looking for candidates with a strong track record of delivering exceptional results, establishing a strong team culture that aligns with Vertex values, and developing...

The territory will cover multi-states and cities including Louisville and Lexington, Kentucky; Cincinnati, Ohio; and Indianapolis, Indiana . The preferred candidate may reside in one of the Blue Grass cities above, ideally Louisville, Kentucky. The Regional Field Leader, Associate Director will be responsible for the oversight of one region in the US Pain Business Unit and will be responsible for the commercialization of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. We are looking for candidates with a strong track record of delivering exceptional results, establishing a strong team culture that aligns with Vertex values, and developing deep...

Role Summary The Senior Manager, S2P Analytics & Master Data serves as the business owner for the Source-to-Pay (S2P) data and analytics foundation. This role ensures that supplier, taxonomy/category, preferred supplier, item/service, contract, risk, and related reference data are accurate, governed, scalable, and fit for purpose—while translating that data into trusted insights, executive narratives, self-service analytics, automation, and AI-enabled decision support. The role leads the business-side governance model, master-data lifecycle, data quality standards, analytics product portfolio, insight-generation capability, and enabling platform requirements across the S2P lifecycle. It partners closely with S2C and P2P Process & Platform Enablement, Strategy/Governance/Excellence, SBE, Finance,...

The Medical Device & Combination Product Development, Associate Director is a hands-on technical leader responsible for advancing drug-delivery device and combination-product programs supporting Vertex therapies. This player-coach role leads the development of mechanical, electromechanical, wearable, on-body, and connected delivery systems. The successful candidate will integrate device engineering, software, human factors, clinical needs, quality requirements, manufacturing considerations, and regulatory strategy to deliver safe, reliable, patient-centered solutions from feasibility through commercialization readiness. Key Duties and Responsibilities Lead device and combination-product development activities from early feasibility through clinical development and commercialization readiness. Define integrated development strategies that address product requirements, user needs, delivery...

The Quality Operations Director provides operational leadership for commercial resupply and lifecycle management of primary and secondary packaging and labeling across a global CMO network. The role translates strategy, capacity plans, and business priorities into an efficient operating model across global CMO portfolios. The Director leads a risk-based quality oversight structure required to assure compliant, reliable, and uninterrupted commercial supply. The role leads a high-performing organization and serves as a senior Quality partner to CMO leadership, Vertex Sr Director of quality operations, Manufacturing &technical operations, Supply Chain, Regulatory, Launch/Technical Quality, and other internal and external stakeholders. KEY DUTIES AND RESPONSIBILITIES...