Vertex Job Trends

Role Overview The Sr. Director, Commercial Technology Business Engagement Leader – Kidney & Patient Services is responsible for executing and operationalizing commercial technology capabilities in direct support of the North America Kidney Business Unit and the Patient Services Program. Reporting the Executive Director, US Commercial Technology this role acts as the day‑to‑day technology leader embedded with Kidney commercial and patient services leadership, accountable for translating business priorities into deliverable roadmaps, funded initiatives, and reliable operations. The Sr. Director ensures that technology solutions—spanning CRM, digital engagement, data, analytics, and AI‑enabled workflows—are implemented effectively, adopted by the business, and operated reliably within...

The Director, Biostatistics will independently perform highly scientific statistical functions in support of the company’s Global Medicines Development and Affairs (GMDA) area on new and complex issues. The incumbent will complete work in a resourceful, self-sufficient manner and create alternative approaches to achieve desired results if needed. In addition, the Director provides independent strategic and technical contributions. The incumbent possess an excellent knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. As a people manager within the organization, has financial accountabilities and human resource responsibilities for assigned staff. Key Duties and Responsibilities Directs one or more...

General/ The Senior Director, CGT Quality Systems, Personalized Medicine provides strategic Quality leadership for personalized medicine and advanced cell therapies across the patient journey. The role is accountable for advancing Quality oversight, governance, compliance, and continuous improvement while ensuring efficient, patient-centric process across the end to end patient journey. This highly cross-functional position requires strong matrix leadership and partnership with Global Quality and Manufacturing, MS&T, Regulatory, Commercial, and Supply Chain stakeholders. Success requires the ability to influence enterprise decisions, build strong partnerships, and drive alignment through executive presence and effective communication. The ability to balance long-term vision with flawless execution...

Committed to advancing breakthrough treatments for patients with immune-mediated diseases, Vertex is building the clinical organization to match its scientific ambition in immunology. We are seeking a physician-scientist with a comprehensive understanding of molecular pathways as drivers of inflammatory and autoimmune diseases across a range of organs — and of the investigative treatment landscape targeting those pathways — to help shape Vertex's immunology portfolio beyond existing programs. Povetacicept, our lead immunology asset, is a differentiated TACI-Fc fusion protein that dually inhibits BAFF and APRIL, now advancing into a broad portfolio of antibody-mediated autoimmune indications with compelling early signals. As Executive...

Vertex is seeking a Senior Director, Solution Architect – Core Technology to serve as a senior individual contributor responsible for defining and driving an integrated architecture strategy across infrastructure and collaboration platforms in a global, GxP-regulated biopharma environment. This leader will establish the foundational architecture function within Core Technology and partner closely with domain leaders across cloud, network, collaboration, end-user computing, workplace technology, and service management. This role will ensure that enterprise technologies are cohesive, scalable, secure, and compliant, while helping shape a unified AI and digital workplace strategy across Microsoft 365, cloud platforms, and end-user environments. This role will...

The Portfolio & Program Management Business Technology Director is a role within the Portfolio & Program Management (PPM) organization and newly formed Center of Excellence. The incumbent is responsible for business ownership of technology platforms and AI tools supporting PPM and the broader Transactions, Alliances, and Portfolio Management (TAPM) organization, with accountability for enabling integrated planning, portfolio reporting and analytics, and scalable new ways of working. This role leads cross-functional efforts to evolve project management systems, strengthen data governance, and advance an integrated, AI-ready portfolio technology environment. Key Duties and Responsibilities Partner with TAPM leadership to shape and execute the...

The Kidney Territory Account Manager (KTAM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs), developing a strategic business plan, communicating thorough disease and product knowledge to HCPs and centers of care. This role must understand market dynamics in rare, complex disease states, demonstrate excellent judgment, and be motivated by the desire to improve patients' lives. The KTAM will report into a Regional Field Leader (RFL) and is responsible for leading engagement with nephrologists and serving as an account manager for specialty kidney clinics. Key Duties and Responsibilities Establishes meaningful and professional relationships with nephrologists and related...

The Clinical Study Quality Lead (SQL), Associate Director is responsible for advanced quality assurance oversight of clinical trial operations and applicable vendors, across a range of study phases within assigned disease area(s). The SQL will ensure clinical trials are conducted in accordance with GCP requirements, applicable protocols, Vertex policies and procedures and quality standards as set forth in the Quality Management System. Overall, the SQL is responsible for the development and execution of audit/quality plans, accurately identifying and communicating compliance risks and overseeing action plans to mitigate risks, real-time study inspection readiness oversight, and collaboratively identifying and driving inspection preparedness...

The State Government Affairs Director is responsible for supporting the company’s state government affairs strategy across several functional areas, including marketing, communications, policy, and medical affairs within their designated region. This role will help lead the company’s ongoing efforts to build and sustain meaningful relationships and collaborations to support the needs of patients and advance our company’s goals. This role will be responsible for grassroots campaigns execution across disease areas. Field-based position. Incumbent resides in the region (TX, TN, AR, LA, OK) Key Duties and Responsibilities Develops, coordinates, and leads the company’s state/regional public policy efforts. Collaboratively creates and leads...

The Senior GCP Operational Quality Manager conducts quality assurance oversight and management activities of clinical trial operations to ensure Vertex trials are conducted in accordance with Good Clinical Practice (GCP) guidelines, applicable regulations, protocols and Vertex policies and procedures. These activities include the development and execution of study level audit plans, accurately identifying and communicating compliance risks and overseeing action plans to mitigate risks, monitoring quality issues and compliance metrics, investigation and CAPA management, and proactive inspection readiness activities. Key Duties and Responsibilities Serves as the Quality Lead for assigned clinical programs providing GCP compliance interpretation, consultation, and other support...

Vertex is seeking an experienced scientist eager to help develop cutting-edge small molecules and the science underpinning the analytical control of their syntheses. As a member of the Drug Substance Control Strategy team in Analytical Development, this role will support synthetic drug development programs at Vertex with a focus on small molecule drug substance process and control strategy development across clinical and commercial-enabling phases. Specifically, the individual will oversee and execute experiments to develop the overall control strategy for novel drug substances, collaborate closely with associated CMC functions, and act as a subject matter expert liaison with our global network...

Job Summary The Principal Engineer, VaiDA Mobile Experience will help bring Vertex’s AI experience tool, VaiDA, to life through intuitive, high-quality mobile experiences that make AI accessible wherever work happens. This role will design and develop secure, performant, and user-friendly mobile capabilities that connect seamlessly to Vertex’s AI and agentic platform, while also supporting existing mobile applications across Vertex. The ideal candidate combines strong mobile engineering expertise with a sharp eye for usability, polish, and responsiveness, and can translate complex AI-driven functionality into clear, elegant mobile interactions. This person will play a key role in making VaiDA a trusted and...

The Senior Medical Director, Patient Safety, Disease Area Safety Head (DASH) will lead all safety and benefit-risk related activities for products within the role's Disease-area and/or Franchise, including pre-franchise products from first in-human clinical trials, into and throughout commercialization. This role will assist Global Patient Safety (GPS) Leadership in ensuring the consistency and compliance in the safety assessment, analysis and reporting for all designated product(s) throughout Vertex’s world markets. Directly and/or via oversight of direct reports, the role will lead pre-marketing risk assessment, planning for First-In-Human (FIH) studies, safety content of key Modules (SCS, CLO, Labelling) in regulatory authority submissions...

The Clinical Development Associate Medical Director will serve as the Medical Lead for clinical trials, working with cross-functional teams on trial strategy, design, execution, and reporting. In addition to oversight and accountability for the study as a whole, this role will serve as the internal primary Medical Monitor accountable for monitoring the safety of enrolled subjects and ensuring scientific integrity. The incumbent may participate in other projects to support the clinical development program. Key Duties and Responsibilities Participates in the development of Study Protocols, Investigator's Brochures, Clinical Development Plans and other key documents in conjunction with other line functions and...

The Manufacturing Process & Technical Quality Associate Director provides end-to-end l quality oversight for cell and gene therapy programs across clinical development, commercialization, product launch, and post-approval lifecycle management. The role is responsible for establishing product quality standards for both established and emerging technologies, ensuring alignment with regulatory expectations and industry best practices, and proactively identifying and mitigating product quality risks throughout the product lifecycle and end to end patient journey. This position partners closely with Manufacturing, Technical Operations, Regulatory Affairs, and Quality stakeholders to support program execution and governance, ensuring business, regulatory, quality, and operational objectives are achieved while...

This notice is being provided as a result of the filing of an application for permanent alien labor certification for the below job opportunity. Any person may provide documentary evidence bearing on the application to the Certifying Officer, U.S. Department of Labor, Employment and Training Administration, Office of Foreign Labor Certification, 200 Constitution Avenue NW, Room N–5311, Washington, DC 20210. Phone (202) 693-2991. Employer Vertex Pharmaceuticals Incorporated Chemistry Manufacturing Controls Manager Job Location 50 Northern Ave., Boston, Massachusetts 02210 Openings 1 Job Type Full Time Duties Review chemistry manufacturing control (CMC) sections of regulatory submissions, as well as...

The People Analytics Sr. Manager will play a pivotal role in shaping Vertex’s HR data strategy by leveraging advanced analytics, experimentation, and storytelling to drive data-informed decisions across the employee lifecycle. This role will partner closely with HR and business leaders to uncover insights, design experiments, and communicate findings that influence talent strategies and organizational effectiveness. The People Analytics Sr. Manager will be focused on building scalable data and AI solutions and translating research and analytics into actionable business insights Key Duties and Responsibilities · Lead the design and execution of people analytics projects that support strategic HR initiatives, including...

Vertex is seeking a talented, experienced analytical chemist for late-stage product development in a commercial setting with an interest in Process Excellence. Working directly with our contract manufacturing organizations and a highly diverse group of scientists at Vertex you will solve complex problems encountered in commercial production/manufacturing of drug products. You will be part of an organization that thrives on innovation and is at the forefront of implementing Quality by Design and Continuous Manufacturing. To be considered for this position the applicant will need to be a collaborative, experienced and competent analytical chemist with a history of developing, implementing and...

The Senior Director, Business Operations Lead is a senior role within the Business Operations function supporting Commercial Manufacturing and Technical Operations (CMTO). Reporting to the Executive Director, Business Operations and Performance , this role is accountable for product-level business leadership across commercial manufacturing activities, with a primary focus on CDMO business management, manufacturing performance governance, readiness and growth planning, cost of goods oversight, and scenario-based business decision support. This individual represents the business position for assigned product(s) across governance forums and key cross-functional decision-making bodies. The role ensures that product business requirements are translated into manufacturing priorities, performance expectations, contractual...

The Senior Medical Science Liaison (Sr MSL) will play a crucial role in supporting the pain program, with a specific focus on near-term launch. The Sr MSL serves as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with (Allied) Health Care Providers/Professionals (HCPs) and other key stakeholders involved in healthcare decision making to ensure the appropriate dissemination of clinical, scientific, and health economic data with respect to pain and Vertex’s compounds in a timely, ethical, and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights...

Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. The Associate Director role is within HEOR’s Analytics Center of Excellence (CoE), a specialized team that provides strategic and technical support to HEOR, Market Access & Pricing, and the broader commercial organization. In this role, the Associate Director will primarily support HEOR disease/asset teams in real-world observational and claims data research activities. The Associate Director will support colleagues looking to answer key questions that can be addressed...

Role Summary We are seeking a n innovative high performing individual to support global commercial Field (Veeva CRM) platform delivery. This role will integrate AI-driven solutions into CRM processes, enabling scalability, operational efficiency, and enhanced demand management. The ideal candidate will bring strong organizational, communication, and analytical skills, with a focus on leveraging AI tools and methodologies to optimize platforms, streamline governance, and improve team operations in a regulated, global environment. Additionally, the role will emphasize ensuring operational efficiency with Managed Service Providers (MSPs) and adherence to DevOps standards and best practices. Key Responsibilities Business Analysis Gather, analyze, and document...

The Senior Administrative Assistant provides experienced office/business support to a department. The Senior Administrative Assistant generally reports directly to a(n) Country Manager, Executive Director or Vice President-level manager. Key Duties and Responsibilities Manages calendars for assigned personnel, including meeting scheduling (both internal and off-site meetings), accepting/declining invites, meeting prioritization, securing conference rooms, ordering catering and "day-of" logistical and administrative support Serves as a departmental resource for Vertex's internal technologies (i.e; Procurement, SharePoint, Concur, Vertex U, VLearn, etc.) Exchanges and integrates information from stakeholders into departmental reports Books flights/hotels, completes expense reports, and arranges team lunches/dinners and offsite meetings for assigned...

We are seeking a dedicated and skilled Senior Research Associate to join our Tissue Dissection Group within our Molecular & Cell Biology group. The successful candidate will play a critical role in generating high-quality cells and tissue samples from primary human organs, contributing to various Vertex research programs. This position requires expertise in human tissue dissection, a commitment to excellence, and a deep respect for the gift of donated human tissues. Key Duties and Responsibilities Perform dissection of human tissues, including dorsal root ganglia (DRG), lungs, kidneys and precision-cut tissue slices. Develop and optimize dissection workflows and methods to enhance...