Vertex Job Trends

As a key Team Manager and leader in the Strategic Sourcing function, the Director, Strategic Sourcing Enterprise Third-party Risk Process & Governance leader is responsible for leading the operational execution of the end-to-end third party risk process as a key member of the Central Risk Management team. This role is responsible for shaping, driving and managing central third-party risk management processes, supporting cross-functional teams, and ensuring consistent application of risk policies and procedures across the third-party/supplier life cycle. The Director will collaborate closely with business owners, risk SMEs, sourcing teams and the rest of the Central Risk Management team to...

The Financial Analyst is a member of Vertex's Global FP&A Organization. This role will help support the annual budget process, monthly forecasting and management reporting, the Long-Range Plan (LRP) and other ad hoc analyses. The role will often partner with other members of the global FP&A and international finance teams as well as accounting, HR and GIS. Key Duties and Responsibilities Supports the annual budget process and monthly forecasting processes by partnering with finance colleagues on reporting of actual results against budget, prior forecasts and historical performance. Supports the Long-Range Plan process including scenario modeling and preparation of presentation materials....

The Director, GMP Operational Quality (Compliance) responsible for oversight of Commercial and/or Development Quality team activities, technical development of personnel, and ensuring the quality of deliverables and oversight of QMS system records (deviations, CAPA, and change controls) supporting cell and gene therapy programs. The Director is an advanced technical resource in the principles and application of quality assurance and compliance, has experience in participating in cross-functional teams working with deviations, root cause analysis, and CAPAs, as well as developing and communicating department QMS metrics and leading internal Tier meetings such as investigation and change control review boards. The incumbent is...

The Associate Scientific Director, US Pain will play a pivotal role in providing scientific support for the Pain therapeutic area. This individual will work closely with the Scientific Director, US Pain, and be responsible for developing and executing the medical communication strategy and plan, ensuring alignment with corporate and patient needs. Collaborating closely with the North American (NA) Medical Directors and a cross-functional team—including Clinical Development, NA Field Medical Affairs, HEOR, Market Access, Marketing, Regulatory Affairs, and the Global Medical Affairs Lead, the Associate Scientific Director will ensure that scientific and medical strategies are strategically aligned and effectively implemented. This...

Vertex is seeking a strategic and collaborative marketing professional to join our US Kidney Business Unit to support our aspirations of bringing Povetacicept to patients, a Phase 3 investigational therapy that has the potential to transform lives across multiple serious diseases. The Senior Marketing Manager, US Kidney - Pove will lead the strategic execution for the HCP marketing team alongside The US Kidney marketing team, which is preparing for potential commercialization of an investigational therapeutic being studied for the treatment of Immunoglobulin A nephropathy (IgAN) and other B cell-mediated diseases. This individual will lead the development and execution of marketing...

The Pricing & Market Access Director is responsible for supporting the development of Market Access strategies for a product or indication, as well as partnering cross-functionally on the Commercial and Development strategies. Key Duties and Responsibilities Supports Global payer strategic planning and execution to advance value and access optimization Supports the development of Market Access strategies and core pricing & access deliverables operating within the Global Commercial model Ensures the payer position is consistently represented to internal cross-functional stakeholders and ensure robust strategic input into commercialization and development decisions Ensures robust value proposition and integrated evidence plans are optimized to...

Vertex is seeking a strategic and collaborative marketing professional to join our US Kidney Business Unit to support our aspirations of bringing Povetacicept to patients, a Phase 3 investigational therapy that has the potential to transform lives across multiple serious diseases. The Senior Marketing Manager, US Kidney - Pove will lead the strategic execution for the HCP marketing team alongside The US Kidney marketing team, which is preparing for potential commercialization of an investigational therapeutic being studied for the treatment of Immunoglobulin A nephropathy (IgAN) and other B cell-mediated diseases. This role will be pivotal in shaping and delivering impactful...

Vertex is seeking a talented field professional to join our US Diabetes Business Unit to support our aspirations of bringing multiple novel therapies to people living with Type 1 Diabetes (T1D). This role will be responsible for the Southwest region covering AZ, NV, NM, CO, HI and southern CA The Cell Therapy Account Manager (CTAM) will be responsible for leading prospective treatment center engagements, facilitating seamless adoption of Vertex cell therapies and providing proactive ongoing account management. They will need to identify and engage appropriate center stakeholders, educate on the treatment process and logistics, and deeply understand key center drivers...

JOB TITLE Process Dev Engineering Scientific Associate LOCATION 316 - 318 Northern Avenue , Boston, MA 02210 OPENINGS 1 DUTIES Supports the development of upstream or downstream production processes for cell therapy projects. Supports technology transfer to CMO and provides manufacturing support for GMP production. Supports a fully integrated team to facilitate the success of projects Utilizes understanding of principles of molecular and cell biology techniques when troubleshooting typical problems. Applies statistical principles to guide process optimization. Conducts cell culture experiments, characterization and data analyses in support of process characterization and improvement. Supports technical reports, regulatory filings,...

POSITION SUMMARY Vertex is seeking a highly motivated Accounting Systems & Consolidation Manager to join our Global Accounting Team This role is responsible for managing the global consolidation process with a continuous improvement mindset and working closely with key stakeholders to maintain and enhance our key accounting systems and applications, such as HFM, Oracle EBS and Blackline. We are looking for an individual who is passionate about leveraging technology to streamline operations, improve efficiency, and modernize accounting processes. We are also looking for a candidate committed to continuous learning and professional development The role provides an opportunity...

JOB TITLE Validation Manager LOCATION 50 Northern Ave, Boston, MA, 02210 OPENINGS 1 DUTIES Provides direction and technical leadership to validation contractor(s) to achieve effective and efficient resources utilization . Employs a “hands-on approach” to leading the team, managing people, systems and equipment validation activities. Ensures that validation work follows all safety standards, conforms to end-user requirements/specifications, cGMP compliance, and that validation activities are tracked and completed within guidelines and schedule. Expected to execute tasks and responsibilities with minimal guidance demonstrating outstanding multi-tasking, problem solving and excellent communication skills, in a dynamic and challenging internal manufacturing environment....

As a member of Vertex’s Investor Relations team, the I nvestor R elations Analyst is responsible for key activities supporting quarterly earnings call preparation , quarterly shareholder analyses, investor conference s, consensus reporting , stock charts and analyses, calendar/deliverables prioritization, leveraging AI tools to maintain competitive awareness, and supporting the IR team and Executive Committee as needed. This role provides support for the IR team and key insights for various Finance functions (FP&A, Accounting, BD, etc.). This position is based in our Boston, MA location (Seaport area) and requires a hybrid work schedule with 3 days in office/2 days remote...

We are seeking a talented, self-motivated and collaborative in-vivo pharmacologist to join the integrated pharmacology team supporting late-stage drug discovery. The ideal candidate will have a strong foundation in pharmacology, work with a high degree of independence and be adept at conceptually designing, executing and interpreting in vivo/ex vivo experiments to establish therapeutic proof-of-concept across diverse disease areas. Key Duties and Responsibilities Designs and conducts elaborate, conceptually connected, multi-component in vivo/ex vivo experiments to demonstrate proof-of-concept in preclinical disease models including pharmacokinetic, pharmacodynamic and efficacy relationships. Perform advanced and/or complex experimental assay development and troubleshooting. Collates and interprets complex data...

Vertex is seeking an experienced commercial leader to implement field sales and non-personal promotion tactics in support of the North America Commercial (NAC) business. The Customer Strategy & Execution Lead (CSEL) will partner with North America commercial organization to implement the go-to-market (GTM) strategy and deliver customer solutions that meet the business needs. This role will lead a team of Associate Directors, Customer Strategy & Execution Leads and will work directly with the BU stakeholders, Field Operations Leads, Digital Operations Leads, Customer Data Management, and technical stakeholders to optimize HCP customer experience. This role reports to the Executive Director, North...

JOB TITLE GMP Operational Quality Senior Specialist LOCATION 50 Northern Ave, Boston, MA, 02210 OPENINGS 1 DUTIES Supports the principles and application of quality assurance and regulatory compliance. Supports or executes a wide range of standard activities and supports new/existing project initiatives. Supports quality oversight for root-cause analysis and product impact assessment for investigations as a result of deviations and Out of Specification (OOS)/Out of Trend (OOT) investigations ensuring appropriate CAPA actions are implemented/identified. Supports change control assessments, implementation and closure. Identifies and facilitates continuous improvement efforts for quality procedures and systems. Supports drafting and revising Quality...

The Medical Affairs Senior Director provides medical and scientific leadership in Cystic Fibrosis (CF) . This role will work closely with a cross-functional group to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs and will ensure the flawless execution of CF US medical plans. Key Duties and Responsibilities Critically interprets scientific data and determines the potential impact of new research on scientific and medical understanding of assigned products Shares country/regional insights with global teams to ensure global medical strategies and activities reflect the needs of the country/region ; share insights with cross-functional partners...

Vertex is seeking an experienced commercial leader to implement field sales and non-personal promotion tactics in support of the Pain Business Unit (BU). The Customer Strategy & Execution Lead (CSEL) will partner with North America commercial organization to implement the go-to-market (GTM) strategy and deliver customer solutions that meet the business needs. This role will work directly with the BU stakeholders, Field Operations Leads, Digital Operations Leads, Customer Data Management, and technical stakeholders to optimize HCP customer experience. This role reports to the Director, Customer Strategy & Execution Lead. Key Duties and Responsibilities Partner with key business leaders to understand...

Director, HCP Marketing, US Kidney - Pove Vertex is seeking a talented leader to join our US Kidney Business Unit to support our journey to support our aspirations of bringing Povetacicept to patients, a Phase 3 investigational therapy that has the potential to transform lives across multiple serious diseases. The Director, HCP Marketing, US Kidney - Pove leads HCP marketing team for for povetacicept within the US Kidney Business Unit alongside a small team of direct reports, which is preparing for potential commercialization of an investigational therapeutic being studied for the treatment of Immunoglobulin A nephropathy (IgAN) and other B...

The CMC Project Management Associate Director will be responsible for the integration, creation and execution of multiple complex departmental development plans. By partnering closely with Project Leaders and cross-functional Project Team members, the incumbent develops and maintains fully integrated project plans to ensure that deliverables are successfully executed, are in accordance with project objectives, and are within budget. The incumbent is also responsible for comprehensive communication, including status reporting, risk management and escalation of issues to cross-functional stakeholders and Senior Management. Responsibilities include working on departmental organizational projects, creating tools and processes to further streamline and enhance project management flow....

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people living with serious diseases, with a focus on specialty markets. We invest in diseases where there is a significant unmet need and we can have a transformative impact for patients, not just an incremental benefit. We invest the majority of our resources in research and development (R&D) to discover new medicines, because we believe the true value in our industry is unleashed through scientific innovation. Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treat—and even cure—several of...

The Package Engineering Manager will deliver reliably on independent activities within Technical Operations. This role will provide technical support in packaging and process operations, working with internal and external cross-functional teams in a fast-paced environment. The Package Engineering Manager will support completion of project activities and working directly with external Contract Manufacturers. Key Duties and Responsibilities Maintains effective relationships between Vertex and key suppliers of materials, technology, and manufacturing resources Provides technical support on packaging processes to Package Engineering and cross functional teams Author and/or review validation and change control documents such as master batch records, protocols, reports and change...

The External Innovation (EI) Executive Director leads end ‑ to ‑ end identification, evaluation, and advancement of external opportunities that materially strengthen Vertex’s R&D pipeline across modalities (e.g., small molecules, biologics, CGT, RNA, delivery platforms) and enabling technologies (e.g., discovery, translational, and manufacturing tools). The role orchestrates integrated, cross ‑ functional analyses and converts opportunity signals into clear, decision ‑ ready recommendations for EI governance (EI Science, BDSC) and the Executive Committee. Key Duties and Responsibilities Enterprise ‑ wide scouting & horizon scanning Lead systematic, data ‑ driven surveillance of assets, platforms, and enabling technologies irrespective of modality, with explicit...

Vertex is seeking a talented scientist to join our Analytical Development group in Boston, MA. As a member of an industry leading CMC team, this individual will play a central role in advancing transformative medicines treating the underlying cause of serious diseases by leading analytical activities for small molecule development programs from preclinical through to late stage development. Responsibilities include analytical method development and validation, purity and stability characterization of drug substance and drug product, as well as contributing scientifically in the resolution of broader drug development challenges in collaboration with other CMC functions. Experience in laboratory techniques commonly used...

The Senior Manager, External Innovation Portfolio Management and Operations reports into the SD, Portfolio Management & Strategic Operations of External Innovation and is responsible for enabling the team by planning of inbounds evaluations, project management of analysis, monitoring surveillance, tracking internal company/technology evaluation + external opportunities & strategic disease area opportunities that are aligned with the corporate strategy. You will ensure efficient and effective coordination across all research, commercial, and manufacturing functions along with supporting evaluation process phases, lead cross-functional partnerships with the transaction and alliance management teams and manage meetings to ensure communication and alignment across stakeholders. Key Duties...

The Supervisor, Manufacturing Operations leads shift work in the clinical manufacturing facility, assigning work according to detailed schedules and plans. Responsible for daily cGMP operations in the clinical manufacturing area and overseeing the daily work of shift personnel. Responsible for daily operation and staff allocations for shift personnel. Ensures schedule adherence is met daily, troubleshoots, and escalates operational variances. This is a second shift role with a shift schedule of Tuesday - Saturday, 130PM - 10PM (40hrs). Key Duties and Responsibilities Builds and develops an efficient team of 2-8 direct reports capable of consistently producing clinical product according to cGMP...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group’s mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Intelligent supply orchestration and automation solutions Principal Analyst, to join our team and drive our digital transformation...

Vertex is seeking a talented team member to join our Global Commercial Strategy team. The Competitive Intelligence Director will be responsible for executing the competitive intelligence process through collection and generation of strategic analysis and insights across specific disease areas. This position will focus on hematology and neurological diseases. The Director will work under the general direction of the Competitive Intelligence team leadership and will be part of a team that provides insights to help reduce uncertainties and build optimal business decisions. The ideal candidate can work in a dynamic environment and work effectively across cross-functional teams. Additionally, this individual...

Vertex Pharmaceuticals is seeking a highly motivated, collaborative, and innovative Associate Director specializing in analytical CMC strategy to provide scientific leadership within and across functional areas. The Associate Director, Analytical CMC Strategy is the primary analytical liaison for their program(s) and will lead, coordinate, monitor, and collaborate cross-functionally to develop analytical CMC strategies while also providing tactical direction for the execution of the analytical project plan. This is a key leadership position where the incumbent will communicate and execute the analytical strategy and will involve routine interaction with senior management. In this matrix leadership role, the candidate will act as...

Vertex is in an exciting time of growth and innovation, and technology and data are valued as strategic assets. The Data & Software Engineering team in the Data, Technology and Engineering (DTE) organization is seeking an experienced technology lead to contribute to, maintain, and implement the standards, platforms and applications that enable data governance (DG) across the enterprise. As the Senior Principal, Data Governance, you will report to the Director, Data Governance and be responsible for building and managing DG technology platforms and strategy including data catalog, data marketplace, metadata management and integrations that support Vertex’s data strategy. Key Duties...

The Senior Principal Analyst, Medical Writing will provide functional and technical expertise, partnership, and support for the Medical Writing function at Vertex. Primary responsibilities include collaborating with business partners to identify and prioritize opportunities to improve business processes with technology and data, gathering and refining requirements, determining options for solution design, delivering enhancements, supporting integrations, and contributing to technology-driven projects and initiatives. KEY RESPONSIBILITIES Collaborate with Medical Writing business stakeholders to understand their current and future state strategy, needs and requirements from a global perspective Proactively offer solution ideas and potential business process improvements in pursuit of driving efficiencies and...

Vertex Pharmaceuticals is seeking a highly motivated and experienced Senior Manager based in Boston, Massachusetts to join its global accounting team The role will oversee the global month-end close process, manage key relationships with Finance, and lead process and technology transformation initiatives across the global accounting function The successful applicant will have strong leadership experience and be responsible for managing a small, high-performing team across multiple time zones, and play a key role in ensuring the integrity, timeliness, and efficiency of global financial reporting This position involves working collaboratively with stakeholders across multiple teams globally and is highly visible within...

Vertex is a global biotechnology company that operates at the forefront of scientific innovation. We have brought multiple breakthrough therapies to patients with Cystic Fibrosis (CF) and advanced novel treatments such as CASGEVY, a gene therapy for sickle cell disease and beta-thalassemia, and JOURNAVX, the first new class of medicine for moderate-to-severe acute pain in more than two decades. Our research pipeline spans more than a dozen programs targeting the underlying mechanisms of serious diseases, including B cell-mediated renal diseases, APOL-1 mediated kidney disease (AMKD), chronic pain, DM-1, and cell therapies for Type 1 diabetes, among others. The Health Economics...

Vertex MSAT team is seeking a Senior Principal Data Scientist to join a growing team in support of commercial Cell and Gene Therapy programs. This position will be responsible for leading and providing technical support in alignment with defined program priorities pertaining to data acquisition, analysis, trending, visualization, and reporting. Key Responsibilities Identify and develop technical solutions to enable program and company goals. Lead development of data trending visualizations using Statistica and for process parameters Lead the Development of Routine Data Visualization charts and tools Develop scripts for automated reporting of trends and correlations Develop visualization for acknowledged alarm reporting...

We are adding to our passionate, patient and customer-centric team to support our journey to advance, develop, and deliver cell and genetic therapies supporting Hemoglobinopathies. At Vertex, the diversity and authenticity of our people is part of what makes us unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear to be the place where an authentic, diverse mix of talent want to...

At Vertex, we’re relentless in our pursuit of scientific innovation to create transformative medicines for people with serious diseases. We are currently seeking a Heme Territory Manager (HTM) to support our Sickle Cell Disease (SCD) and Transfusion-dependent β-thalassemia (TDT) Heme Business Unit. As part of a national team, the Heme Territory Manager (HTM) will approach each day with a passion for improving the lives of people living with Sickle Cell Disease and Transfusion-dependent β-thalassemia. This role is a field-based position focused on driving Demand Generation (100%) as a performance driven individual contributor who promotes the safe and effective use of...

At Vertex, we’re relentless in our pursuit of scientific innovation to create transformative medicines for people with serious diseases. We are currently seeking a Heme Territory Manager (HTM) to support our Sickle Cell Disease (SCD) and Transfusion-dependent β-thalassemia (TDT) Heme Business Unit. As part of a national team, the Heme Territory Manager (HTM) will approach each day with a passion for improving the lives of people living with Sickle Cell Disease and Transfusion-dependent β-thalassemia. This role is a field-based position focused on driving Demand Generation (100%) as a performance driven individual contributor who promotes the safe and effective use of...

At Vertex, we’re relentless in our pursuit of scientific innovation to create transformative medicines for people with serious diseases. We are currently seeking a Heme Territory Manager (HTM) to support our Sickle Cell Disease (SCD) and Transfusion-dependent β-thalassemia (TDT) Heme Business Unit. As part of a national team, the Heme Territory Manager (HTM) will approach each day with a passion for improving the lives of people living with Sickle Cell Disease and Transfusion-dependent β-thalassemia. This role is a field-based position focused on driving Demand Generation (100%) as a performance driven individual contributor who promotes the safe and effective use of...

The Customer Engagement Platform Architect will serve as the strategic and technical lead responsible for designing, optimizing, and scaling Vertex’s customer engagement platforms across marketing, field CRM, and digital channels. This individual will play a critical role in shaping the future-state architecture that enables seamless, compliant, and personalized engagement with healthcare professionals (HCPs), patients, and caregivers. The role requires deep expertise in enterprise platform integration, data-driven engagement, and governance, with a focus on ensuring scalability, compliance, and business value. Key Duties and Responsibilities Platform Architecture & Strategy Define and maintain the enterprise architecture for customer engagement platforms (e.g., Salesforce Marketing...

Vertex currently operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Pain, and the first CRISPR-based, gene therapy for sickle cell disease and transfusion-dependent beta thalassemia. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Type 1 diabetes, APOL-1 Mediated Kidney Disease, IgA nephropathy, Duchenne Muscular Dystrophy, and Alpha-1 Antitrypsin Deficiency (AATD). The Regional Access and Reimbursement Associate Director will help ensure appropriate access and reimbursement of Vertex cellular...

General/ Vertex is in an exciting time of growth and innovation, and technology and data are valued as strategic assets. We’re seeking a visionary Director of Engineering and Data Governance to lead the strategy, planning, and governance of data and custom software solutions for our research and pre-clinical teams. Reporting to the Sr. Director of DSE (Data & Software Engineering) Governance, you will drive innovation, ensure data quality, and enable impactful research through cutting edge data & AI products. This is a high-visibility leadership role with significant influence on Vertex’s scientific and business outcomes. Your expertise in understanding engineering capabilities,...

Vertex currently operates at the forefront of rare disease scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Pain, Type 1 diabetes, IgA Nephropathy (IgAN), APOL-1 Mediated Kidney Disease, and Muscular Dystrophy, among others. The Director, Market Access Transformation & Strategic Marketing is accountable for leading the development of a strategic “above-brand” market access platform to help guide...

We are currently growing a passionate patient and customer-centric team to support our journey to advance, develop, and deliver cell & genetic therapies supporting Hemoglobinopathies. At Vertex, our people are part of what makes us unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear to be the place where an authentic, diverse mix of talent wants to come, to stay, and do...

MBA Summer Associate, Commercial The Vertex MBA Summer Associate Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our internship program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are fearless" is in everything we do. Each summer, top MBA candidates from business schools around the world find all this and more through our MBA...

Associate Director of Rebate Operations The Associate Director of Commercial Rebate Operations has a critical role, reporting to the Director, Rebate Operations team within the US Market Access organization . This is an exciting opportunity for a subject matter expert that applies an enterprise-level mindset and technical expertise at the intersection of data, process optimization, automation and innovation. This individual is responsible for building the Commercial team to enable management of traditional and value-based US Commercial payer rebates. The ideal candidate is passionate about patients, focused on driving for results, and is willing to be involved in hands-on execution while...

We are currently growing a passionate patient and customer-centric team to support our journey to advance, develop, and deliver cell & genetic therapies supporting Hemoglobinopathies. At Vertex, our people are part of what makes us unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear to be the place where an authentic, diverse mix of talent wants to come, to stay, and do...

The Associate Director, Government Pricing Operations is a key leadership role within Vertex’s U.S. Market Access- Access Operations and Analytics team. This individual will lead government pricing (GP) analysis, calculations, and reporting, ensuring compliance with federal and state requirements. The role is integral to the company’s readiness for product launches across multiple therapeutic areas and the evolving complexity of pricing regulations. This individual will manage a team of GP analysts, collaborate cross-functionally, and serve as a subject matter expert in government pricing methodologies, operations and systems. Key Responsibilities Government Pricing Operations & Compliance Lead the execution of GP calculations and...

At Vertex, we’re relentless in our pursuit of scientific innovation to create transformative medicines for people with serious diseases. We are currently seeking a Heme Territory Manager (HTM) to support our Sickle Cell Disease (SCD) and Transfusion-dependent β-thalassemia (TDT) Heme Business Unit. As part of a national team, the Heme Territory Manager (HTM) will approach each day with a passion for improving the lives of people living with Sickle Cell Disease and Transfusion-dependent β-thalassemia. This role is a field-based position focused on driving Demand Generation (100%) as a performance driven individual contributor who promotes the safe and effective use of...

At Vertex, we’re relentless in our pursuit of scientific innovation to create transformative medicines for people with serious diseases. We are currently seeking a Heme Territory Manager (HTM) to support our Sickle Cell Disease (SCD) and Transfusion-dependent β-thalassemia (TDT) Heme Business Unit. As part of a national team, the Heme Territory Manager, Senior Manager (HTM) will approach each day with a passion for improving the lives of people living with Sickle Cell Disease and Transfusion-dependent β-thalassemia. This role is a field-based position focused on driving Demand Generation (100%) as a performance driven individual contributor who promotes the safe and effective...

Vertex operates at the forefront of scientific innovation. It has seven approved medicines five that treat the underlying cause of cystic fibrosis (“CF”), a life-threatening genetic disease, one that treats severe sickle cell disease (“SCD”) and transfusion dependent beta thalassemia (“TDT”), and one that treats moderate-to-severe acute pain. Our clinical-stage pipeline includes programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, muscular dystrophy, and autosomal dominant polycystic kidney disease. The Senior Director, Global Commercial Strategy CF Pipeline Lead is accountable for understanding...

At Vertex, we’re relentless in our pursuit of scientific innovation to create transformative medicines for people with serious diseases. We are currently seeking a Heme Territory Manager (HTM) to support our Sickle Cell Disease (SCD) and Transfusion-dependent β-thalassemia (TDT) Heme Business Unit. As part of a national team, the Heme Territory Manager (HTM) will approach each day with a passion for improving the lives of people living with Sickle Cell Disease and Transfusion-dependent β-thalassemia. This role is a field-based position focused on driving Demand Generation (100%) as a performance-driven individual contributor who promotes the safe and effective use of Casgevy...

The Senior Director, Regulatory Submission Management champions functional and cross-functional project and submission management excellence. The incumbent is expected to apply deep subject matter expertise in project and submission management to lead and identify opportunities, shape objectives and drive execution of key functional and corporate objectives. This role will be responsible for driving timeline risk mitigation and contingency planning. Key Duties and Responsibilities Provide strategic and operational project, submission and program leadership activities at all stages of the lifecycle (initiation through closeout). Drive communication cross-functionally and with senior leaders on project, submission and program planning topics including timelines, status, risks...

The Pain Territory Account Manager is responsible for plan execution, delivering sales performance, and product promotion in Spokane, WA. (Territory may change upon the needs of the organization). The PTAM must maintain a high level of knowledge within the disease states and product labeling. Activities include disease state and product education to referring HCPs, collaboration with internal and external stakeholders, and shaping and executing sales strategies. The individual in this role must be goal-oriented and accountable for their individual performance, while acting in a professional and compliant manner. This role will drive business growth through effective sales strategies, HCP engagement,...

Vertex is seeking experienced and talented commercial leaders to join our US Pain Business Unit to support our journey to bring forth new options for the treatment of pain. The Territory Account Manager will be responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to generate advocacy and drive sales growth for the US Pain Business Unit, which is preparing for potential commercialization of an investigational novel selective inhibitor of NaV1.8 in acute pain. We are looking for candidates with a strong track record of delivering exceptional results with patient focus, developing...

The Medical Science Liaison (MSL) will play a crucial role in supporting the pain program, with a specific focus on near-term launch. The MSL serves as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with (Allied) Health Care Providers/Professionals (HCPs) and other key stakeholders involved in healthcare decision making to ensure the appropriate dissemination of clinical, scientific, and health economic data with respect to pain and Vertex’s compounds in a timely, ethical, and stakeholder-focused manner. The MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contributing to the...

We are seeking a highly motivated computational biologist with a strong background in computational methods development to join Vertex. This position is part of a rapidly growing Data and Computational Sciences team focused on developing therapies for diseases with serious unmet need. You will play a critical key role in developing cutting-edge computational methods that assess the safety and efficacy of transformative therapeutics. You will also cross-functionally collaborate to develop robust and scalable workflows that address strategic questions across Vertex’s programs. A strong background in computational methods development, a proven track record in Python programming and infrastructure development, and an...

The Clinical Development Medical Director will serve as the Medical Lead for Vertex clinical trials, working with cross-functional multidisciplinary study teams on clinical trial strategy, design and execution and serving as the Medical Monitor responsible for monitoring the safety of enrolled subjects on assigned trials. The incumbent will work on multiple trials in all Phases of clinical development, and may also participate in other selected projects in clinical development. Key Duties and Responsibilities Leads the development of Study Protocols, Investigator Brochures, Clinical Development Plans and other key study documents in conjunction with other line functions and with minimal guidance Serves...

MBA Summer Associate Intern, Finance The Vertex MBA Summer Associate Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our internship program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are fearless" is in everything we do. Each summer, top MBA candidates from business schools around the world find all this and more through our...

The Pain Territory Account Manager is responsible for plan execution, delivering sales performance, and product promotion in Montana. (Territory may change upon the needs of the organization). The PTAM must maintain a high level of knowledge within the disease states and product labeling. Activities include disease state and product education to referring HCPs, collaboration with internal and external stakeholders, and shaping and executing sales strategies. The individual in this role must be goal-oriented and accountable for their individual performance, while acting in a professional and compliant manner. This role will drive business growth through effective sales strategies, HCP engagement, and...

The HCP Marketing, Sr. Manager participates in the day-to-day execution of the marketing strategy by developing marketing tactics that achieve our business objectives ensuring they are delivered to customers effectively. The Sr. Manager will execute HCP activities through peer-to-peer and non-personal promotion (NPP) channels, driving awareness and education of our approved therapies. Key Duties and Responsibilities Develops/updates existing HCP marketing materials that are aligned with marketing strategy and business objectives. Lead branded peer-to-peer activities including speaker programs (content creation, bureau set up, etc.) and advisory boards. Support other critical HCP marketing initiatives and tactical execution (e.g. media planning NPP pull-through)....

The Clinical Pharmacology Associate will analyze and report on clinical pharmacology studies. A professional with non-compartmental PK analysis experience working in the development organization. The Clinical Pharmacology Associate will be a key part of the Clinical Pharmacology function supporting clinical study execution teams. The Clinical Pharmacology Associate, will also be assisting Clinical Pharmacology and cross-functional clinical teams to ensure the successful execution of Clinical Pharmacology strategies. Key Duties and Responsibilities Review pharmacokinetics concentration data & conduct non-compartmental PK analysis Assist in summarizing PK data and generating TFLs to support Clin Pharm updates Quality control (QC) reviews for NCA, TFLs, and...