Vertex Job Trends

The Director, Clinical Pharmacology leads strategic, scientific and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the development of clinical pharmacology plans; assists in departmental management through program reviews and collaborative decision-making; supervises asset leads, provides career development; routinely co-leads cross-functional efforts and leads department initiatives. Key Duties and Responsibilities Guides metabolic, co-dosing and drug-drug interaction issues, collaborating closely with cross functional colleagues Co-leads or serves on cross-functional committees and/or contributes to or leads departmental initiatives Creates protocol concepts and guides protocol start-up including site...

The CMC Statistics Director (Scientific Fellow) provides strategic and technical leadership for the application of statistical sciences across the product lifecycle, including process development, analytical development, manufacturing, process validation, continued process verification (CPV), stability, quality control, and regulatory submissions. This individual will establish and lead the CMC Statistics capability, enabling data-driven decision-making to enhance product quality, process robustness, operational efficiency, and regulatory compliance. The role partners closely with Development, MSAT, Quality, Regulatory Affairs, and Data & Digital teams to ensure the effective application of advanced statistical methodologies across all CMC functions. The position will drive the adoption of best practices...

Manager, Marketing Operations The Marketing Operations Manager serves as the lead and subject matter expert for assigned Communications Review Committee (CRC) team(s), supporting the efficient and compliant review, approval, production, and distribution of branded and non-branded communications. This role partners closely with business stakeholders, agency partners, and cross-functional reviewers to help ensure materials move through the promotional review process in a timely, well-coordinated, and effective manner. In addition to leading planning, forecasting, and review operations for assigned CRC team(s), this individual is responsible for generating performance insights, leading quarterly business reviews, and driving continuous improvement initiatives that enhance efficiency,...

The Associate Director, FP&A is a key member of Vertex’s Finance Business Partnering organization, providing financial leadership and strategic support to the U.S. Kidney team. As Vertex advances toward commercialization of its Kidney portfolio, this role will help shape and deliver near-term and long-term financial goals. This position will play a critical role in supporting pre-launch contracting strategies and post-launch commercial revenue planning in the U.S., a priority market for the Kidney portfolio. The Associate Director will partner across Finance, Market Access, Commercial, Trade, and Analytics to deliver actionable insights, inform decision-making, and help define the key performance indicators that...

The Director, Intellectual Property Operations is responsible for leading and continuous ly improv ing Vertex's IP Operations function. This role focuses on driving operational excellence through strong project execution, project management, communication, collaboration, and managing a team supporting patent and trademark administration, docketing, annuities, budgeting, software assessment, developing standard practices and vendor engagement and management. The position also serves as a key partner to IP attorneys, Finance, Technologists , and external counsel to ensure efficient processes, data integrity, compliance, and successful delivery of strategic initiatives . The Director will report directly to the Executive Director , Intellectual Property for Cell...

The Analytical Science and Technology (AS&T) Principal Scientist, Separation Method Expert, will be responsible for providing scientific and technical expertise within and across functional areas for late-stage & commercial methods and vendor management. S/He will manage the method life cycle, including method remediation, validation, transfer, troubleshooting and investigations for OOT/OOS, along with data trending analysis. Additionally, the principal scientist will partner closely with all stakeholders, and with contract testing sites establishing partnerships to ensure compliance with cGMP and Quality Management systems for the global network to deliver our medicines to patients effectively. Key Duties and Responsibilities Lead analytical method remediation,...

The Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a...

We are seeking a Senior Director, US New Product Planning, to help shape the future of our pipeline and build the foundation for successful US launches. This is a highly visible leadership role for a strategic, commercially minded, and pragmatic leader who thrives at the intersection of asset strategy, US market planning, and enterprise capability building. This role is ideal for someone who has worked in both the US business and on global teams, and who understands what it takes to succeed in the US market across functions—not just within a single discipline. The individual will represent the US perspective...

The Quality Analytics Manager utilizes data analysis skills and tools to evaluate Vertex operations, processes, and systems and recommends strategic process improvements based on research findings. This role is a key contributor in driving data-centric decision making within the Quality organization. The role also advises and supports business partners in design and delivery of data models and data analysis that enhance Vertex delivery and oversight. Key Duties and Responsibilities Identifies, analyzes, and interprets trends and patterns in complex data sets and prepares ongoing reports and data visualizations to support decision-making Develops and implements data analyses, data collection systems and other...

We are seeking a Director, US New Product Planning, Early Market Development to partner closely with the Senior Director Director, US New Product Planning in preparing early pipeline assets for future US success. This role is ideal for a commercially minded, externally oriented leader who is energized by shaping markets well ahead of launch. The successful candidate will focus on early market development and engagement with emerging thought leaders, including both healthcare professional (HCP) stakeholders and patient advocacy / community leaders. This individual will help build the foundational understanding, relationships, and market readiness required to support future launch success in...

We are seeking a Senior Director, US New Product Planning to help shape the future of our pipeline and build the foundation for successful US launches within an expanding and highly visible Business Unit. This is a high-impact leadership role for a strategic, commercially minded, and pragmatic leader who thrives at the intersection of asset strategy, US market planning, launch readiness, and Business Unit build-out. This role is ideal for someone who has worked in both the US business and on global teams, and who understands what it takes to succeed in the US market across functions—not just within a...

Vertex is seeking a highly skilled Senior Azure DevSecOps Engineer to design, implement, secure, and optimize cloud platforms that power enterprise software, data, and AI-driven solutions. This role will be a key technical contributor supporting VaiDA and other strategic initiatives built on Microsoft Azure, Microsoft Foundry, and related cloud technologies. Working closely with software engineers, cloud architects, information security teams, and business stakeholders, this individual will drive the adoption of DevSecOps best practices, cloud automation, infrastructure as code, and secure software delivery pipelines. The ideal candidate combines deep Azure expertise with a strong security mindset and a passion for building...

Job Summary Vertex is seeking a Senior Director, Market Transformation to help position the company as a commercial leader in delivering life-changing medicines to patients through innovative capabilities, cutting-edge solutions, and strategic partnerships. This role will identify emerging market trends, bring external insights into the organization, and translate opportunities into scalable programs that increase awareness for our brands, improve patient access, and support business objectives. The Senior Director will work cross-functionally to shape strategic decisions, accelerate innovation, and strengthen relationships with influential stakeholders across the healthcare ecosystem. This leader will play a critical role in improving patient access to our...

The Director, Marketing Operations, Promotional Materials Management will lead Vertex’s centralized promotional materials operations function across all U.S. products and businesses. This role is responsible for the end-to-end operational management of promotional material review, approval, production, distribution, and lifecycle management, ensuring efficient, scalable, and compliant execution. This leader will operationalize and continuously improve the review committee SOP, strengthen review committee practices across the organization, and drive measurable improvement across people, process, and platform. The role will also oversee coordinator services, including a team of five FTEs, and serve as a key partner to Commercial, Legal, Regulatory, Medical, Compliance, and external...

The Modeling & Simulations Associate Director will be responsible for developing and executing M&S strategies and activities in cross functional drug development project teams in close collaboration with colleagues in Clinical Pharmacology, Biostatistics, Research and other colleagues within the R&D organization. This role determines, plans, and executes technically challenging analyses b y using state of the art Modeling & Simulation methodologies to strongly contribute to critical decision making. Key Duties and Responsibilities As Modeling & Simulations (M&S) lead in one or more cross functional drug development teams, responsibilities include the development and execution of Modeling & Simulation plans and analyses...

Vertex is seeking a talented individual to join our Process Development team as a Scientist. The primary focus of this role is to lead and manage the execution of development studies for a cell-based drug candidate designed to treat diabetes. This is a full-time position based in our Boston, MA facilities, with occasional weekend work required. The Process Development group offers a fast-paced and high energy environment. The right candidate will be a subject matter expert in bioprocess engineering and have a solid technical operations background. Key Duties and Responsibilities Design and execute experiments to develop robust manufacturing processes for...

Reporting to the Director, Materials Operations, this role is responsible for developing and executing the Materials Management Technical Support strategy for Manufacturing support operations, material control process design, compliant material flows, and system reconciliation in support of product commercialization. The individual will also support key Materials Management systems and processes, including change controls, risk assessments, deviations, and GMP documentation. This role provides oversight of commercial material control process development, materials management system design, warehouse material flows and performance monitoring. The Senior Manager will collaborate cross-functionally with Manufacturing, Process Development (PD), Quality Control (QC), Operational Quality, Facilities, Operations, and other stakeholders...

The Senior Biostatistician II will perform scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with guidance and mentoring on new and complex issues. The incumbent will complete assigned work in a resourceful manner and create alternative approaches to achieve desired results. The incumbent will develop a good knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. Key Duties and Responsibilities Within assigned area, designs, develops and executes the technical/statistical infrastructure for the conduct and evaluation of clinical trials, observational studies, or real world data (RWD) investigations, including related areas/activities. Participates...

The Associate Director, Kidney Training & Development is a strategic leadership role responsible for designing and leading capability-building initiatives that support the success of the Kidney business at Vertex. This position oversees more than traditional training and development activities and plays a critical role in advancing leadership development, organizational effectiveness, and field readiness. In addition, this role serves as the primary training lead for our customer engagement liaison team. The Associate Director partners closely with Commercial, Medical, Market Access, HR, Compliance, and other key stakeholders to build a high-performing, customer-centric, and compliant organization. Key Duties and Responsibilities Design, implement, and...

Vertex is seeking a strategic and collaborative marketing professional to join our US Kidney Business Unit to support our aspirations of bringing Povetacicept to patients, a Phase 3 investigational therapy that has the potential to transform lives across multiple serious diseases. The Senior Marketing Manager, US Kidney - Pove will lead the strategic execution for the HCP marketing team alongside The US Kidney marketing team, which is preparing for potential commercialization of an investigational therapeutic being studied for the treatment of Immunoglobulin A nephropathy (IgAN) and other B cell-mediated diseases. This individual will lead the development and execution of marketing...

Role Overview The Sr. Director, Commercial Technology Business Engagement Leader – Kidney & Patient Services is responsible for executing and operationalizing commercial technology capabilities in direct support of the North America Kidney Business Unit and the Patient Services Program. Reporting the Executive Director, US Commercial Technology this role acts as the day‑to‑day technology leader embedded with Kidney commercial and patient services leadership, accountable for translating business priorities into deliverable roadmaps, funded initiatives, and reliable operations. The Sr. Director ensures that technology solutions—spanning CRM, digital engagement, data, analytics, and AI‑enabled workflows—are implemented effectively, adopted by the business, and operated reliably within...

The Director, Biostatistics will independently perform highly scientific statistical functions in support of the company’s Global Medicines Development and Affairs (GMDA) area on new and complex issues. The incumbent will complete work in a resourceful, self-sufficient manner and create alternative approaches to achieve desired results if needed. In addition, the Director provides independent strategic and technical contributions. The incumbent possess an excellent knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. As a people manager within the organization, has financial accountabilities and human resource responsibilities for assigned staff. Key Duties and Responsibilities Directs one or more...