Vertex Job Trends

The Engineering & Applied Physics team at Vertex, San Diego, is looking to add a top-notch Instrumentation Software Engineer to our small, elite team of engineers and physicists. From advanced robotics and automation to microfluidics and cutting-edge microscopy, this unique in-house team develops a wide array of performance-focused technological solutions for the toughest challenges in drug discovery. Where commercial options don’t exist, the team collaborates directly with Vertex scientists to create innovative solutions that enable ground-breaking science and discovery of life-saving medicines. The Principal Instrumentation Software & Application Engineer plays a lead role in defining instrument control architecture, developing control...

The Associate Director is recognized as an expert internally in the principles and application of quality and regulatory compliance. The individual adapts to new and multiple projects, effectively ensuring alignment with corporate goals and compliance with all regulatory requirements. This role is responsible for oversight and coordination of GMP activities in support of Commercial Stability and serves as primary QA contact on cross-functional teams. The Associate Director manages and develops personnel to support department and functional activities. Key Duties and Responsibilities The responsibilities of this role may include, but are not limited to, the following Leads QA oversight of...

The Senior Director, Enterprise Applications will lead a team responsible for architecture, design, development, support, maintenance and future roadmap s for a number of strategic enterprise platforms and HR applications. These systems and technologies include ServiceNow, Workday , Vertex University , and Readcube . The Senior Director, Enterprise Applications will collaborate with senior leaders and other key stakeholders across severa l areas of the business to identify , prioritize and deliver technology solutions in support of their goals and objectives . KEY RESPONSIBILITIES Partner with business stakeholders across Human Resources and many other functional areas in order to manage and...

The Director, Manufacturing Operations Cell Therapy - Drug Substance Drug Product (DSDP) leads a team in the execution of multi-product global production of investigational cell therapy products in the Type 1 Diabetes (T1D) disease areas. The role is responsible for the compliant production of cell therapy products and the oversight and training of the manufacturing team to ensure that the company effectively and efficiently delivers therapies to patients. This role is directly responsible for leading internal manufacturing teams and working with external manufacturing on the clinical production of cell therapy products. This role will also cultivate and leverage multiple cross-functional...

The Director, Pain, Global Value & Access Strategy role will serve as Market Access Lead for the chronic indications (DPN/LSR/PNP) across our Pain portfolio, with a specific focus on suzetrigine. Based on positive Phase 2 data, Vertex is advancing into pivotal development in diabetic peripheral neuropathy (DPN) and lumbosacral radiculopathy, or LSR, which is pain caused by impairment or injury to nerve roots in the area of the lumbar spine. The individual will be responsible for leading the development of Global Market Access strategies, as well as co-lead the Global Commercial Team across the Vertex Pain portfolio. The role reports...

Vertex is hiring a Head of Access Operations and Analytics , reporting to the Vice President, US Market Access. This leader will oversee multiple teams including but not limited to Government and State Drug Transparency Price Reporting, Gross-to-Net, the US Market Access Data & Analytics Center of Excellence and Access Operations teams. This high-performing function is critical to supporting the success of patient access to Vertex medicines, informing the revenue forecast, ensuring product availability across the US and Canada, and providing data governance and access analytics in support of the Access Strategy and Access Field teams. Importantly, the leader will...

The Sr. Scientist, Biologics, Cell, and Gene Therapy (BioCGT) holds a matrix position within the Analytical Science & Technology (AS&T) team, reporting to the Vertex Manufacturer Science & Technology function. The successful candidate will act as the subject method expert (SME) responsible to support program(s) through the late-stage drug development lifecycle, Biologics Licensure application (BLA), and Life Cycle management. This role will provide expertise and comprehensive analytical supports to assay validation, transfer, and lifecycle management for late-stage and commercial applications. The Sr. Scientist will collaborate closely with all departments within Vertex and with contract testing sites establishing solid partnerships to...

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops, and feel valued by the Vertex community. Not only will co-ops...

The Quality Product Complaints Associate Director is responsible and accountable for providing quality oversight of the Product Complaint Quality System and the Global Recall and Defect Notification Systems. This role will support quality activities associated within the Compliance team and will partner with various internal and external cross-functional teams including Global Patient Safety, Supply Chain/Trade and Distribution, Medical Information, Guidance and Patient Support, Quality Assurance, Contract Manufacturing Organizations, and external Call Centers. The Associate Director also drives continuous improvement in Vertex quality processes and governance to assure Vertex remains adherent to regulatory expectations and supports QA operational quality oversight and...

Vertex Pharmaceuticals is seeking a highly motivated Senior Research Associate to join the Protein Sciences team in San Diego. The Protein Sciences team is responsible for guiding our drug discovery programs through key molecular insights that underlie disease target function and modulation. The successful candidate will support the advancement of our research programs to create transformative medicines for patients with serious diseases through the generation of high-quality recombinant proteins for biochemical, biophysical and / or structural biology experiments. KEY RESPONSIBILITIES With minimal supervision, perform hands-on expression, purification, and characterization of mammalian integral membrane proteins for assay development and biophysical experiments....

The Senior Medical Science Liaison (Sr MSL) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights, and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources, and provide the...

The Product Quality Director is accountable for end-to-end quality oversight of small molecule, biologics, or device program(s) throughout clinical development, commercialization, filing, approval, launch, and post approval lifecycle management activities. This oversight includes setting and maintaining overall Quality strategies in support of commercialization efforts including establishing relevant product quality standards for current or novel technologies (including devices where applicable), ensuring QA and cross-functional alignment with industry and regulatory expectations, identifying product quality risks and mitigations throughout the development lifecycle of the assigned program, through commercialization and decommissioning. The candidate should have a good understanding of drug development and commercialization and...

Vertex is seeking a talented strategic colleague to serve in a critical role supporting the D isease S trategy T eam Program Office in the Office of the CEO . The Strategy & Operations Director will partner closely with a Disease Area Executive (DAE) to drive special initiatives to support a particular DST . We are seeking a candidate that has a strong track record in strategic role s , along with cross functional collaboration and effective communication s kills to apply for this opportunity . Key Duties and Responsibilities Partners with DAE to lead strategic projects and high-profile initiatives...

General/ Vertex is seeking an experienced technology leader to lead the strategy, planning, and delivery to support the Medical Affairs business function across all disease areas and regions. The AD, Business Engagement & Technology will primarily partner with the ‘Medical Information and Innovation’ team as well as external affairs teams within Chief Patient Office organization to create and execute technology strategy in concert with business strategy. This role will work directly with the business partners to understand the business needs and vision and will be accountable for defining technology roadmaps, identifying solutions, and finding synergies across other commercial, medical, and...

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops, and feel valued by the Vertex community. Not only will co-ops...

The Senior Director, GMP Operational Quality Assurance will be responsible for the oversight of Site Quality Operations for the Manufacturing of Cell & Gene products . The role will be responsible for leading the Quality on site operations team across multiple shifts for internal clinical and commercial manufacturing operations . Responsibilities include day- to-day operational quality oversight for internal batch record review, batch disposition and manufacturing operations across the end-to-end manufacturing processes for the manufacture of clinical and commercial intermediates and drug product batches. Responsibility includes ensuring all shift quality operational activities are completed in time by identifying technical risk...

The Senior Manager, Quality Assurance Contamination Control and Sterility Assurance is recognized as having expertise in the principals and application of sterility assurance and providing technical support for manufacturing of cell and gene therapy programs within cGMP manufacturing. This role will partner with stakeholders to define strategies for contamination control activities in key areas that include facility and equipment design and qualification (e.g. cleanroom, isolators, autoclaves, etc.), environmental qualification and monitoring programs, and operational practices (e.g. gowning, cleaning and sanitization, etc.). This individual will interface with internal manufacturing sites to support the maintenance of critical cGMP contamination control activities and...

Reporting to the Director, Contract Operations, this role is responsible for the lifecycle management process of agreements within the US Market Access Organization (Commercial and Government (ex Medicare Advantage and Part D)) Full Line Wholesalers, Specialty Distributors, Specialty Pharmacies, Group Purchasing Organizations, PBMs, and other segments and channels as required. This position will work closely with the Director, Contract Operations and cross-functional leaders to ensure agreements meet business, legal, operational and compliance needs across several therapeutic areas. The ideal candidate will be familiar with and highly conversant in various segments of market access, discuss and incorporate contracting strategies and tactics,...

The Director, Site Activation will oversee the Study Start-Up portfolio within a dedicated region and across therapeutic areas, managing the Study Start-Up personnel and regional management of Start-Up and acting as a member of the Global Start-Up leadership team. This role takes direction from the SSU Head and in coordination with the global study Start-Up team, will set the strategic direction for Study Start-Up planning in the region and will provide oversight and leadership to drive the Study Start-Up activities associated. Furthermore, the Director, Site Activation will work collaboratively with all business partners to communicate decisions, issues, risks and mitigations...

Vertex is seeking a talented Research Scientist to join a collaborative research team focused on non-viral delivery within Vertex Cell and Genetic Therapies (CGT) in Boston, MA. The group’s mission is to deliver the next generation genetic therapies impacting several therapeutic areas. We are looking for a candidate with a strong desire to deliver innovative new medicines to patients in need. In this lab-based role , the ideal candidate is strongly experienced in biologics engineering, bioconjugation of antibodies and antibody-like scaffolds, biologics purification and characterization, and structure/function relationships. Prior experience in lipid nanoparticle formulation and biologics discovery are strongly preferred....

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) team powering Research Technology & Biopharmaceutical Manufacturing have a core mission to improve the lives of patients through digital, data, and technology innovation. Vertex is accelerating our capabilities, technology and data to augment our manufacturing and supply mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Director, Digital Process Control Solutions to join our team and drive our digital evolution initiatives. The Director, Digital Process Control...

The Medical Operations Associate Director provides project management leadership to cross-functional medical affairs teams and manages the strategic planning and tactical execution of medical affairs projects, including medical plans, across clinical stage and/or marketed programs. Collaborates with key stakeholders across multiple functions within medical affairs (including global and regional medical directors, global medical information, medical communications) and to develop role and disease area training plans across Medical Affairs. This role is expected to apply project management knowledge and experience in the development, initiation, planning, execution, maintenance, and closing of projects as well as other departmental initiatives. Key Duties and Responsibilities...

The Associate Director – Business Interpreter, Finance Reporting & Analysis COE is critical to financial data strategy and execution, and champions data-driven decision making across the enterprise. Reporting to the Senior Director, Finance Reporting & Analysis COE , this role will serve as a critical liaison between data analysts, finance teams, and business stakeholders, translating complex data insights into actionable business strategies. The Business Interpreter will play a key role in enhancing data-driven decision-making and ensuring that our financial reporting aligns with organizational goals. This role will develop and execute a comprehensive data and analytics strategy, data integration and governance...

The Medical Science Liaison (MSL) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights, and contribute to the designing and execution of the Medical Affairs strategy and plan. The MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources, and provide the latest emerging data...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) team powering Research Technology & Biopharmaceutical Manufacturing have a core mission to improve the lives of patients through digital, data, and technology innovation. Vertex is accelerating our capabilities, technology and data to augment our manufacturing and supply mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Associate Director, Registration Solutions, to join our team and drive our digital evolution initiatives. The Associate Director, Registration Solutions is...

Vertex is an established, innovative biotech focused on developing lifesaving treatments for patients around the world. Our Data and Knowledge Management team is operating at the intersection of science, data, and technology to create transformative medicines for people with serious diseases. Software engineers in our Data and Knowledge Management team focus on building complex full stack web applications, API's and microservices that support research, clinical and business operations at Vertex. We are passionate about delivering elastic, scalable, and highly available serverless solutions utilizing the latest cloud technologies. We are responsible for maintaining and developing a robust API environment, design system...

The Senior Director, Head of Project Management Office (PMO) is a strategic leader responsible for overseeing the Cell & Gene Therapy (CGT) and biologics CMC project portfolio within the Biopharmaceutical Sciences Cell and Gene Therapy (BiopharmSci CGT) organization. This position reports to the Executive Director, CMC Project Management and Strategic Operations, BiopharmSci CGT. The Head of PMO will lead a high-performing team of project managers who are responsible for translating CMC strategies into executable project plans and driving the project execution. This individual will drive project portfolio planning/execution and build scalable project management capabilities. The successful candidate will bring extensive...

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) team powering Research Technology & Biopharmaceutical Manufacturing & Supply have a core mission to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. We are seeking a dynamic and experienced Senior Director, Solutions Architecture to join our team and drive our digital transformation...

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops, and feel valued by the Vertex community. Not only will co-ops...

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops, and feel valued by the Vertex community. Not only will co-ops...

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops, and feel valued by the Vertex community. Not only will co-ops...

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops, and feel valued by the Vertex community. Not only will co-ops...

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops, and feel valued by the Vertex community. Not only will co-ops...

The Marketing Senior Manager will support the delivery of the marketing strategy by overseeing development of HCP and/or patient and caregiver tactics, and ensuring those tactics are delivered to customers effectively and monitored for effectiveness. Key Duties and Responsibilities Develops and updates marketing materials which are aligned with marketing strategy and business objectives (including branded websites, interactive visual aids, sales brochures, etc.) Enhances customer engagement by ensuring marketing pieces have been uploaded to the CRM platform, administering speakers programs, coordinating conference activities (including promotional booths, conference materials) Analyzes complex digital and print material usage metrics for performance reporting and assessing...

The Marketing Associate Director is accountable for understanding the market landscape, defining and developing key business activities and tactics to support goals of the brand/portfolio, and measuring the success of those activities/tactics. Key Duties and Responsibilities Partners with brand/team-lead to help shape the brand strategy, segment the market, develop messaging and launch into new segments, including label expansions Directs the development and implementation of strategic and tactical plans for assigned product Collaborates with Vertex external communications review committee to approve materials for external use with customers Generates and consolidates key insights across HCPs and patient stakeholders through market research, ad...

The Technical Accounting Associate Director is primarily responsible for researching and documenting accounting positions and analyses for a variety of complex areas, as well as proactively monitoring and performing impact analyses with respect to new accounting standards and other regulatory developments. This position is based in our Boston, MA office, located in the Seaport area. This role requires a hybrid work schedule 3 days in office & 2 days remote on a weekly basis. Key Duties and Responsibilities Perform technical accounting research and prepare analyses and accounting whitepapers, including complex areas such as collaboration accounting; revenue recognition; variable interest entities/other...

Vertex is seeking a hands-on, experienced consolidations leader with accounting systems and process expertise to join our Global Accounting organization. The Director, Accounting Systems & Consolidation will o versee the global close and consolidation process and drive accounting system and financial reporting excellence. In addition, the Director will closely partner with IT and other stakeholders to maintain and enhance our key accounting systems and applications such as HFM, Oracle EBS, and Blackline. This newly established role is ideal for a motivated leader who can effectively lead our small team of experienced professionals to align diverse stakeholders, foster collaboration, and deliver...

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group in Boston, MA. The Health Economics & Outcomes Research Senior Director will lead HEOR strategies and execution of evidence generation that optimize the value proposition of Vertex’s kidney pipeline assets through each stage of development, including launch and post-launch phases. This position reports to the Vice President Global HEOR. Key Duties and Responsibilities Serves as the HEOR Kidney Disease Area Lead Develops the HEOR strategy for assets in the Kidney Disease Area from early development through product lifecycle Serves as HEOR...

The Medical Affairs Associate Medical Director will provide medical leadership for the CF Franchise. This role will be accountable for working with the medical team for the assigned country, for the development and implementation of Country Medical strategy and plans and will work in partnership with the Country Manager as well as other cross functional team colleagues to ensure access to company’s products, develop and implement cross functional country plans aligned with patient, HCPs’ and broader corporate needs. This role is responsible for building and encouraging scientific excellence within the team and engaging in close partnerships with HCPs, scientific societies...

Vertex Pharmaceuticals uses cutting edge science and technologies to create transformative therapies for the treatment of the most serious diseases with unmet medical need. We are seeking an industry experienced individual to join our Global Archive Management group. The Archive Management group is responsible for the global storage and distribution of Vertex’s small molecule assets. The Research Scientist, Archive Management works with a high degree of independence to identify and solve tough problems repeatedly, across several critical and diverse projects. This role will coordinate, manage and refine processes for the receipt, storage and distribution of compounds using highly automated processes,...

The DTE Medical and External Affairs Technology team is playing a crucial role in enabling our commercial expansion as Vertex commercializes into new disease areas and brings more transformative medicines to patients around the world. As the Scientific Content and Publications Platform Lead, you will be responsible for overseeing the technology implementation and operations, including but not limited to platform enhancements and vendor relationships, for scientific content and publications software platforms supporting global medical affairs team. This role focuses on ensuring the integrity, scalability, and performance of our publication strategy and planning platforms while driving innovation and alignment with business...

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group in Boston, MA. The Health Economics & Outcomes Research Senior Manager (Pain) will participate in the development and execution of Health economics and outcomes research studies in support of Vertex's products. This position reports to the Senior Director HEOR, Pain. Key Duties and Responsibilities Executes HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset...

The Real World Evidence (RWE) Associate Director is an integral member of the RWE team, who leverages expertise in epidemiology and real world data to develop fit-for-purpose observational research, and to inform internal and external stakeholders on natural history (NH) of disease and real world outcomes within their assigned therapeutic area. The RWE Associate Director works cross-functionally to support the execution of observational research across the portfolio. This position is Boston based with a hybrid schedule, allowing for 2 days per week remote work and 3 days per week in the office in the Boston Seaport district. (Relocation assistance is...

The Director of Cell and Gene Therapy Commercial Supply Chain will lead the slot management strategy, development, and operations to support Vertex’s autologous cell and gene therapy program. The slot management model includes dynamic, short range, and situational planning and operations to allow visibility and patient scheduling. The Director will also be responsible for establishing, maintaining, revising, and executing slot management rules and principles to ensure patients are appropriately scheduled within manufacturing capacity and regulatory requirements. This includes chairing steering committee meetings and key presentations to cross-functional leaders. Through cross-functional alignment, the Director will drive the creation, maintenance, and usage...

The Associate Quality Director conducts quality assurance oversight and management activities of clinical trial operations to ensure Vertex trials are conducted in accordance with Good Clinical Practice (GCP) guidelines, applicable regulations, protocols and Vertex policies and procedures. These activities include the development and execution of study level audit plans, accurately identifying and communicating compliance risks and overseeing action plans to mitigate risks, monitoring quality issues and compliance metrics, investigation and CAPA management, and proactive inspection readiness activities. This role is located at Vertex’s Leiden Center Building (LC1), 316-318 Northern Ave, Boston, MA-02210. This is a second shift role from Wednesday...