Vertex Job Trends
48
Active Jobs (Last 14 Days)
11
Fresh Jobs (Last 3 Days)
100%
Jobs with Salary Data
Recent Job Posting Activity (30 Days)
Job Category Distribution
Current Vertex Jobs, Salary Data, and Stats
In the last two weeks, Vertex has posted 48 positions. 8% of those roles offer remote or hybrid work. We've been tracking Vertex since February 7, 2025.
Career Tracks Currently Hiring
Currently Hiring Office Locations
Boston, MA Providence, RI San Diego, CA Seattle, WA 5000 - Vertex US - Boston and 16 moreCurrent Vertex Jobs
Last updated: Dec 16, 2025
Showing 48 active jobs. Active jobs were posted in the last 14 days. Fresh jobs were posted within the last 3 days. Click a row for more details.
Showing filtered results for ""
| Role | |
|---|---|
Associate Director, Digital Marketing - HCPApply →Fresh
Comm
Dec 16 $0 - $0
Boston, MAThe Associate Director, Digital Marketing HCP will be responsible for developing and executing digital marketing strategies to enhance the engagement and communication with healthcare professionals (HCPs) within the US Kidney Business Unit. This role will focus on creating and implementing omnichannel communication journeys, non-personal promotion (NPP) execution, and leveraging search and AI strategies. The Associate Director will also serve as the Legal and Regulatory HCP Digital lead, ensuring alignment with regulatory and compliance standards. Key Duties and Responsibilities Develop and execute HCP digital marketing strategies, including content creation and omnichannel communication journeys, to reach and engage HCPs effectively Lead the... | |
HCP Marketing Associate DirectorApply →Fresh
Comm
Dec 16 $162,800 - $244,200
Boston, MAThe Marketing Associate Director is accountable for understanding the market landscape, defining and developing key business activities and tactics to support goals of the brand/portfolio, and measuring the success of those activities/tactics. Key Duties and Responsibilities Partners with brand/team-lead to help shape the brand strategy, segment the market, develop messaging and launch into new segments, including label expansions Directs the development and implementation of strategic and tactical plans for assigned product Collaborates with Vertex external communications review committee to approve materials for external use with customers Generates and consolidates key insights across HCPs and patient stakeholders through market research, ad... | |
Associate Director, Media/Social Marketing - HCPApply →Fresh
Comm
Dec 16 $0 - $0
Boston, MAThe Associate Director, Media/Social Marketing - HCP will lead the development and execution of comprehensive media and social marketing strategies to enhance the digital presence and engagement of the US Kidney business unit. This role will focus on driving influencer strategies, managing digital opinion leaders (DOLs), and leading HCP media planning and execution. The ideal candidate will have a strong background in media planning, media buying, analytics measurement, as well as channel selection and optimization. Key Duties and Responsibilities Oversee media planning and media buying activities to ensure effective allocation of resources. Develop Marketing content for media platforms for HCPs.... | |
Associate Director, NA Cystic Fibrosis Analytics & ReportingFresh
Dec 15 $157,800 - $236,700 Boston, MA Apply →Associate Director, NA Cystic Fibrosis Analytics & ReportingApply →Fresh
Dec 15 $157,800 - $236,700
Boston, MAVertex is seeking to hire an Associate Director, NA Cystic Fibrosis (CF) Analytics & Reporting to join the North America Forecasting, Analytics, and Insights team in the Commercial organization. This role will provide analytics support for strategic commercial initiatives by identifying and quantifying market drivers, barriers, and opportunities using advanced analytical methods. Additionally, this role will provide support for ongoing analytics, quantitative tracking, and reporting of national and sub-national commercial performance of the NA CF business. This individual will work cross-functionally and lead requirement gathering, development, execution, and insight generation for performance analytics, dashboards, and present insights to stakeholders. The... | |
Project Management & Strategic Operations Associate DirectorFresh
Dec 15 $155,700 - $233,600 Boston, MA Apply →Project Management & Strategic Operations Associate DirectorApply →Fresh
Dec 15 $155,700 - $233,600
Boston, MAVertex is seeking a talented strategic & operations colleague to serve in a critical role joining our US Pain Business Unit to support the ongoing launch of Journavx in moderate to severe acute pain, the first new class of medicines in over two decades on our journey to fundamentally transform pain management. The Associate Director , US Pain Strategy & Operations will drive critical strategic planning and execution as continue to scale launch within the US Pain Business Unit. We are seeking a candidate that has a strong track record in strategic and project management roles to report directly into... | |
Executive Medical Director, Global Medical Lead (Pain)Fresh
Med Practice
Dec 15 $316,800 - $475,100 Boston, MA Apply →Executive Medical Director, Global Medical Lead (Pain)Apply →Fresh
Med Practice
Dec 15 $316,800 - $475,100
Boston, MAThe Executive Medical Director, Global Medical Lead (GML), Pain is a critical leadership role in Global Medical, responsible for the global medical strategy and impl eme ntation and tracking of global activities for a designated disease area(s) . Key responsibilities include, but are not limited to, disease area specific Integrated Medical Plan development, including the publication plan, global launch strategy and execution, scientific leadership, external medical expert engagement, and strategic alignment with commercial and other cross-functional business partners. This leader will also be critical in leading post-approval evidence generation strategy in the disease area. This leader reports directly to the... | |
Senior Manager, Third-Party Risk Management (TPRM)Fresh
Remote
Dec 15 $126,400 - $189,600 Boston, MA Apply →Senior Manager, Third-Party Risk Management (TPRM)Apply →Fresh
Remote
Dec 15 $126,400 - $189,600
Boston, MAThe Senior Manager, Third-Party Risk Management (TPRM) will serve as the Subject Matter Expert (SME) for the operational processes of the enterprise-wide TPRM program. Reporting to the Senior Director of Strategic Sourcing Enterprise Third-Party Risk Management, this role will focus on managing day-to-day TPRM operations, ensuring seamless stakeholder engagement, and providing excellent user support. The Senior Manager will act as a liaison between vendors and business owners, triaging questions, facilitating communication, and tracking issues to resolution. The role also includes supporting the use and maintenance of TPRM tools (e.g., ProcessUnity, Archer, RiskConnect, or similar platforms) and driving the resolution of... | |
Director, Talent Acquisition, CommercialApply →Fresh
Comm
Dec 15 $181,200 - $271,800
Boston, MAVertex is seeking a hands-on, strategic, and collaborative Director of Talent Acquisition to lead talent acquisition efforts across all U.S. Commercial Business Units. The ideal candidate is a bold, business-minded talent advisor who thrives in a fast-paced, matrixed environment and is passionate about building teams that drive commercial excellence. The Director will serve as a trusted partner to senior leaders, shaping and executing talent strategies that align with Vertex’s mission to transform lives. Key Duties and Responsibilities · Own and actively manage a desk of high-impact requisitions, including key and business-critical roles, ensuring timely and high-quality outcomes. · Drive and... | |
Learning Management Systems ManagerApply →Fresh
Tech
Dec 15 $119,700 - $179,600
Boston, MAThe Learning Management Systems (LMS) Manager will oversee the administration and optimization of Vertex University’s LMS platform, Cornerstone OnDemand. This role ensures seamless delivery of learning programs by managing system configurations, resolving technical issues, and partnering in the implementation of new releases. The position plays a critical role in supporting Vertex’s learning strategy and enhancing user experience across the organization. Key Duties and Responsibilities Serve as the primary administrator for Cornerstone OnDemand, managing system configurations and ensuring data integrity Partner with stakeholders in development of custom and automated LMS reporting Advise on best practices for learning assignments and data collection... | |
Chief of Staff - Chief Digital and Information Officer (CDIO)Fresh
Dec 15 $182,800 - $274,200 Boston, MA Apply →Chief of Staff - Chief Digital and Information Officer (CDIO)Apply →Fresh
Dec 15 $182,800 - $274,200
Boston, MAVertex Pharmaceuticals is seeking an experienced and driven Technology focused Chief of Staff to support our Chief Digital and Information Officer in leading Vertex’s digital transformation and IT strategy. This high-impact role functions as a trusted advisor and operational leader for the Office of the CDIO, ensuring that Digital, Data, and Technology initiatives are executed with excellence and aligned with our mission to improve patients’ lives. You will drive strategic planning, oversee key initiatives, enhance operational processes, and facilitate cross-functional collaboration. The ideal candidate is a proactive problem-solver with a strong background in digital and technology leadership and exceptional interpersonal... | |
Principal Research Associate, BioanalyticalFresh
Research
Dec 15 $86,500 - $129,800; $0 - $0 Boston, MA Apply →Principal Research Associate, BioanalyticalApply →Fresh
Research
Dec 15 $86,500 - $129,800; $0 - $0
Boston, MAEmployer Vertex Pharmaceuticals Incorporated JOB TITLE Principal Research Associate, Bioanalytical LOCATION 316-318 Northern Ave, Boston, Massachusetts, 02210 OPENINGS 1 DUTIES Conduct bioanalytical assays to support preclinical study sample analysis. Carry out method development and optimization to quantify target proteins. Maintain proper documentation of experiments and support QC data review. Collaborate with cross-functional teams to review study design and interpret results. Prepare technical reports and presentations to document and communicate results. REQUIREMENTS Employer will accept a Master’s degree or equivalent, in applied science, biotechnology or a related field and 3 years of experience in the job offered or... | |
Analytical Development ScientistApply →Research
Dec 12 $113,464 - $132,400; $0 - $0
Boston, MAEmployer Vertex Pharmaceuticals Incorporated JOB TITLE Analytical Development Scientist LOCATION 316 - 318 Northern Avenue, Boston, Massachusetts 02210 OPENINGS 1 DUTIES Perform a variety of well-defined, supportive functions including leading design and execution of analytical procedures that support development of cell therapy products. Develop, qualify and validate new test methods for characterization, purity and potency of hESCs and iPSC derived cell intermediates and drug products. Rapidly incorporate and adapt longstanding methods to the most recent FDA guidelines. Generate hypotheses and creative solutions to pursue Project goals, set new experimental directions, and overcome obstacles. Establish assay design criteria... | |
Quality Control Senior SpecialistApply →Quality
Dec 12 $94,300 - $141,400; $0 - $0
Boston, MAEmployer Vertex Pharmaceuticals Incorporated JOB TITLE Quality Control Senior Specialist LOCATION 1 Harbor Street, Boston, Massachusetts, 02210 OPENINGS 1 DUTIES Provide a variety of analytical functions that occur in the QC department supporting validation, testing and reporting of in-process, release and stability samples. Ensure activities occur in an efficient and cGMP compliant manner while fostering the Vertex vision and values. Serve as RSL representative in cross-functional, cross-departmental working teams and/or working with outside vendors to meet all laboratory needs. Coordinate and facilitate laboratory activities to meet commitments on-time. Maintain accurate laboratory records and adhere to cGMP/GDP expectations.... | |
Vertex Summer Intern 2026, Preclinical FormulationApply →Dec 12 $0 - $0; $20 - $32
San Diego, CAKickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that... | |
Associate Director, Consumer Media Strategy & Execution - US KidneyApply →Dec 12 $0 - $0
Boston, MAAssociate Director, Consumer Media Strategy and Execution will lead the development and execution of comprehensive media strategies to enhance the digital presence and engagement plan as a critical part of the US Consumer Marketing team within the US Kidney Business Unit. This role will focus on designing the consumer media plan around a focused understanding of the patient journey with disciplined follow through and drive for optimizing patient experience. The ideal candidate will have a strong background in media planning, media buying, analytics measurement, as well as channel selection and optimization. Key Duties and Responsibilities Oversee media planning and media... | |
Pharmacology Research ScientistApply →Research
Dec 12 $105,600 - $158,400
Boston, MAWe are seeking a talented, self-motivated and collaborative in-vivo pharmacologist to join the integrated pharmacology team supporting late-stage drug discovery. The ideal candidate will have a strong foundation in pharmacology, work with a high degree of independence and be adept at conceptually designing, executing and interpreting in vivo/ex vivo experiments to establish therapeutic proof-of-concept across diverse disease areas. Key Duties and Responsibilities Designs and conducts elaborate, conceptually connected, multi-component in vivo/ex vivo experiments to demonstrate proof-of-concept in preclinical disease models including pharmacokinetic, pharmacodynamic and efficacy relationships. Perform advanced and/or complex experimental assay development and troubleshooting. Collates and interprets complex data... | |
Associate Director, Consumer Digital Marketing - US KidneyApply →Comm
Dec 12 $0 - $0
Boston, MAAssociate Director, Consumer Digital Marketing will be responsible for developing and executing digital marketing strategies to enhance the engagement and communication with US immunoglobulin A Nephropathy (IgAN) patients as part of the US Povetacicept Marketing team within the US Kidney Business Unit. This role will focus on creating and implementing the consumer omnichannel communication journeys, including but not limited to display, CRM, social, and search integration while considering the evolving AI landscape. The Associate Director will also serve as the Consumer Digital lead for CRC, ensuring alignment with regulatory and compliance standards. Key Duties and Responsibilities Develop and execute consumer... | |
Vertex Summer Intern 2026, Formulation DevelopmentApply →Dec 12 $0 - $0; $20 - $32
Boston, MAKickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that... | |
Microsoft 365 Security & Data ProtectionApply →Remote
Dec 12 $141,200 - $211,800
Boston, MAThis person will be responsible for the day-to-day administration of the Microsoft 365 Purview and Entra ID platforms, as well as the Veritas Data Insight platform, in a heavily-regulated GxP environment. This person will be responsible for working with business and technical leaders to identify systems containing critical data and labeling them accordingly. S/he will be responsible for creating data protection awareness programs for end-users and using standardized metrics to document compliance. S/he will participate in incident investigations and assist, when necessary, to resolve complex software and hardware problems. This person will be required to follow strict change control processes... | |
Associate Director, Marketing Science (Portfolio)Apply →Comm
Dec 12 $0 - $0
Boston, MAVertex is seeking an Associate Director (AD) to join the Forecasting, Analytics and Insights team in the North America Commercial organization. The AD will be responsible for delivering commercial insights to inform strategic choices and commercialization decisions for launched and pipeline assets in disease areas such as hemoglobinopathies (e.g., sickle cell disease, beta thalassemia), cystic fibrosis, pain, and other serious diseases. The AD will partner with the US & Canada business units and the Global Commercial Brand teams, to maintain a clear understanding of the overall business and key questions for the programs, and will formulate and execute an insights... | |
Federal Accounts Lead - East, Pain BUDec 11 $166,400 - $249,600 5010 - Vertex US - Distribution Apply →Federal Accounts Lead - East, Pain BUApply →Dec 11 $166,400 - $249,600
5010 - Vertex US - DistributionFederal Accounts Lead, US Pain Business Unit Vertex is seeking a highly motivated and experienced Federal Accounts Lead to join our US Pain Business Unit to support our journey to bring forth new options for the treatment of pain. The Federal Accounts Lead will be part of the strategic accounts field team for the US Pain Business Unit, for the commercialization of JOURNAVX in acute pain. We are seeking a candidate who has a strong track record of engaging key DoD and VA decision-makers to drive access and use of innovative pain medicines . The Federal Accounts Lead will report... | |
Commercial Supply Chain Associate DirectorApply →Comm
Dec 11 $149,300 - $224,000
Boston, MAThis role will lead and drive the Sales and Operations Planning (S&OP) process for Casgevy, a commercially launched product within Vertex’s Cell and Gene Therapy portfolio. This is a critical role within the Vertex Supply Chain, that includes the ability to perform complex modeling, utilizing assumptions, demand and capacity to meet both short- and long-term requirements. The Associate Director will be responsible for working with the commercial team to align assumptions and the demand plan, External Manufacturing to work with CDMO’s to align capacity assumptions, Finance, Materials, Quality Control and Regulatory that will culminate in the monthly S&OP process. This... | |
Pain Territory Account Manager - Colorado Springs, COComm
Dec 11 $133,600 - $200,400 United States - Field Based Apply →Pain Territory Account Manager - Colorado Springs, COApply →Comm
Dec 11 $133,600 - $200,400
United States - Field BasedThe Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a... | |
Principal Technology Analyst, MarTech PlatformsApply →Dec 10 $158,800 - $238,100
Boston, MAThe Principal Analyst will serve as a strategic liaison between Marketing stakeholders and technical delivery teams, ensuring that business objectives are translated into actionable technology solutions. This role focuses on enabling and optimizing the Marketing Technology ecosystem—including Marketing Automation, Customer Data Platforms (CDP), and Web technologies—while maintaining compliance with legal and privacy regulations in a highly regulated industry. The ideal candidate combines deep technical expertise with strong business acumen and solution architecture principles. Key Duties and Responsibilities Business Engagement & Requirements Translation Execute the translation of defined business milestones, objectives , and KPIs from Marketing into clear, actionable functional requirements,... | |
Medicinal Chemistry Research ScientistApply →Research
Dec 10 $100,000 - $150,000
Boston, MAVertex Pharmaceuticals has an exciting opportunity for a Research Scientist in the field of medicinal chemistry. Job responsibilities include the preparation of both single and focused sets of small organic molecules, developing and optimizing synthetic methods, creating and interpreting project-relevant Structure-Activity Relationship (SAR) and problem solving. Candidates must demonstrate an expert understanding of organic reaction mechanisms, formulation of executable synthetic routes, up to date understanding of contemporary synthetic methods as well as an ability to balance rational concepts with creativity which includes the development of new synthetic methodology as needed. The successful candidate will have the ability to work independently... | |
Pain Territory Account Manager - Denver (North) - COComm
Dec 10 $133,600 - $200,400 United States - Field Based Apply →Pain Territory Account Manager - Denver (North) - COApply →Comm
Dec 10 $133,600 - $200,400
United States - Field BasedThe Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a... | |
Executive Director, Head of NA Commercial OperationsApply →Comm
Dec 10 $265,600 - $398,400
Boston, MAThe Executive Director (ED), North America Commercial Operations leads a team that supports multiple in-line disease areas, supporting each US Business Unit and their respective leadership teams within North America Commercial. The ED oversees 6 district functions Commercial Data Management, Digital Customer Engagement, Field Operations, Marketing Operations, Field Training, and Business Engagement Leads. This position reports to the Vice President, North America Commercial Operations, Insights & Analytics and is located at our headquarters in Boston, MA in the Seaport area. Key Duties and Responsibilities Leads 6 distinct functions Commercial Data Management, Digital Customer Engagement, Field Operations, Marketing Operations, Field Training,... | |
Senior Statistical Programmer IIApply →Remote
Data
Dec 9 $124,600 - $186,900; $0 - $0
Boston, MAEmployer Vertex Pharmaceuticals Incorporated JOB TITLE Senior Statistical Programmer II LOCATION 50 Northern Ave., Boston, Massachusetts, 02110 OPENINGS 1 DUTIES Codes complex SAS programs (including Macro language, SAS/STAT and SAS/GRAPH) for applications designed to analyze and report complex clinical trial data and for electronic review, exchange, transformation, and submission of data in CDlSC SDTM format; consistently meeting objectives of the study. Performs quality control checks of SAS code and output produced by other Statistical Programmers. Demonstrates proficient knowledge of clinical development and medical data. Solves clinical trial reporting problems and has a proven technical proficiency in... | |
Internal Audit ManagerApply →Dec 9 $111,700 - $167,600
Boston, MAThrough internal audits the Internal Audit Manager will identify risk areas, evaluate business process controls and complete test plans on operational audits. Additionally, this role will provide recommendations to improve the effectiveness and efficiency of operations and business systems. This role will also participate in ensuring that the yearly internal control review is brought to fruition by interacting with SOX testers, other stakeholders, and subject matter experts on special projects and the development and execution of departmental goals. Key Duties and Responsibilities Plans and performs financial, operational and, as applicable, IT audits; reviews related records for compliance with established and... | |
Associate Director, GMP Operational Quality (Biologics and Device Quality)Quality
Dec 9 $154,100 - $231,200 Boston, MA Apply →Associate Director, GMP Operational Quality (Biologics and Device Quality)Apply →Quality
Dec 9 $154,100 - $231,200
Boston, MAThe Associate Director, GMP Operational Quality will provide leadership and quality oversight for contract testing laboratories (CTLs) supporting Vertex’s biologics and combination product portfolio across development, PPQ, launch, and commercial lifecycle management. This role ensures that analytical testing, method execution, and data generated by external laboratories meet Vertex, global regulatory, and data integrity standards. Key Duties and Responsibilities Serve as the primary QA lead for CTLs supporting release, stability, characterization, and device-related testing for Vertex’s biologics and combination products. Provide quality oversight for analytical method qualification/validation, method transfer, and lifecycle management activities executed by CTLs. Review and approve analytical protocols,... | |
Principal Clinical ProgrammerApply →Remote
Tech
Dec 8 $161,803 - $204,200; $0 - $0
Boston, MAEmployer Vertex Pharmaceuticals Incorporated JOB TITLE Principal Clinical Programmer LOCATION 50 Northern Ave. , Boston, MA, 02110 OPENINGS 1 DUTIES Utilize SAS and other supporting tools to design, write, validate , and maintain programs to meet specifications in a quality, timely and productive manner following standard development procedures. Solid understanding of Clinical data warehouse platform ( Elluminate ), act as a subject matter expert for all the end users. Excellent programming skills to perform all the report development, data analytics and configuration in Elluminate application. Generate and maintain all required documentation, including the development of specifications,... | |
Senior Director, Global Medical Affairs - NephrologyMed Affairs
Dec 7 $240,000 - $360,000 Boston, MA Apply →Senior Director, Global Medical Affairs - NephrologyApply →Med Affairs
Dec 7 $240,000 - $360,000
Boston, MAThe Medical Affairs Senior Director provides medical and scientific leadership in the assigned Therapeutic Area(s) (TA). This role will work closely with a cross-functional group to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs and will ensure the flawless execution of Nephrology medical plans. Key Duties and Responsibilities Critically interprets scientific data and determines the potential impact of new research on scientific and medical understanding of assigned products Develops medical affairs plans, including Launch and Life Cycle Management plans Shares country/regional insights with global teams to ensure global medical strategies and activities reflect... | |
Accounting Transformation Associate DirectorApply →Dec 5 $144,000 - $216,000
Boston, MAVertex is seeking a hands-on, experienced team member with a passion for transformation and bringing new capabilities to our organization. The Associate Director, Accounting Transformation will manage and support initiatives that will modernize, streamline, and enhance processes impacting the Accounting and Finance teams. This new role is ideal for a motivated individual who thrives on working on meaningful projects while bringing stakeholders along through all facets of the journey. Key Duties and Responsibilities Manage daily aspects of various transformation projects while keeping deliverables on track to meet agreed upon timelines. Drive analysis of large data sets and provide clear interpretations... | |
Associate Director, Internal AuditApply →Dec 5 $0 - $0
Boston, MAThe Associate Director of Internal Audit will support the development and execution of a risk-based audit plan to evaluate and improve the effectiveness of Vertex’s risk management, control, and governance processes. Reporting to the VP, Chief Audit Executive (CAE), this role will assist in implementing departmental strategy, contributing to annual functional goals, and overseeing portions of the SOX testing program. Key Responsibilities Maintain strong knowledge of Vertex’s core business and assist in developing a risk and control assurance program aligned with company objectives and risk appetite . Contribute to the development of departmental strategy, Audit Committee reporting, and departmental initiatives... | |
DMPK Senior Research Fellow - BiotherapeuticsApply →Data
Dec 5 $232,800 - $349,200
Boston, MAWe are seeking an accomplished and strategic leader to serve as Senior Research Fellow, DMPK Project Lead to guide the DMPK strategy for our Biotherapeutics portfolio including protein, antibody, ADC and cell and genetic therepies. The responsibilities will span from early research through clinical development. This leader will play a central role in ensuring that PK, bioanalysis, ADME, and translational PKPD insights are fully integrated into program decision-making and development plans. The ideal candidate will bring deep strategic and technical expertise in DMPK for one or more biotherapeutic modalities described above, have demonstrated leadership in a matrixed environment, and have... | |
Associate Director, Compliance Business PartnerApply →Comm
Dec 5 $166,500 - $249,800
Boston, MAAssociate Director, Compliance Business Partner (Hybrid) Why Join Us? Vertex is a transformative biotechnology company that creates new possibilities in medicine to transform diseases and improve people’s lives. The company currently has approved products in cystic fibrosis, acute pain, sickle cell disease, and beta thalassemia. It has also developed a deep pipeline, investing billions of dollars into R&D over the past two decades. Vertex is seeking an experienced Compliance professional to join its Office of Business Integrity & Ethics (OBIE) as Associate Director, Compliance Business Partner providing support to our cell and gene, and kidney teams. OBIE is responsible for... | |
Manufacturing Operations Support & Materials Management Manager (3rd Shift, 4/10)Manuf
Dec 5 $123,600 - $185,300 Boston, MA Apply →Manufacturing Operations Support & Materials Management Manager (3rd Shift, 4/10)Apply →Manuf
Dec 5 $123,600 - $185,300
Boston, MAThe Manufacturing Operations Support & Materials Management Manager is the accountable off-shift superintendent for cGMP cleaning and materials management support for cell manufacturing sites located in Boston and Cambridge. This role provides general oversight for Materials Management and Manufacturing Support functions. The Manager will partner with with Manufacturing Operations, Quality Assurance, Facilities, and Vertex managed service partners for troubleshooting and resolving issues as well as escalations to leadership for direction as necessary. As the off-shift superintendent, the Manager ensures compliant operations, cGMP cleaning, and materials management through proactive management. This leadership position monitors service level agreements with managed service partners... | |
Director, Protein TherapeuticsApply →Dec 4 $188,800 - $283,200
Seattle, WADirector, Protein Therapeutics Vertex is seeking an accomplished and highly skilled scientific leader to join our Protein Therapeutics team in Seattle. This role will be critical in advancing our pipeline of innovative biologics from early development to clinical readiness in a dynamic, fast-paced, and highly collaborative environment. The ideal candidate will leverage deep scientific expertise, strong leadership and mentorship skills, and strategic vision to deliver transformational protein-based therapeutics for diseases with serious unmet medical need. Key Duties & Responsibilities Provide strategic leadership and scientific direction for a team specializing in protein engineering and production while fostering a culture... | |
Senior Medical Science Liaison- North Carolina South/Central & VirginiaMed Affairs
Dec 4 $171,300 - $245,000 United States - Field Based Apply →Senior Medical Science Liaison- North Carolina South/Central & VirginiaApply →Med Affairs
Dec 4 $171,300 - $245,000
United States - Field BasedThe Senior Medical Science Liaison (Sr MSL) (Nephrology) for Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of IgA Nephropathy (IgAN). The Sr MSL will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the designing and execution of the Medical... | |
Operational Area Quality Associate DirectorApply →Quality
Dec 4 $154,100 - $231,200
Boston, MAThe Associate Director, GMP Operational Quality is an advanced technical resource in the principles and application of quality assurance and compliance. This role is responsible for primary QA oversight of commercial drug substance manufacturing performed at Vertex’s external vendors as well as secondary quality support of commercial drug product manufacturing vendors. This position ensures robust sterile manufacturing controls, commercial supply continuity, support for global jurisdictional expansion, and high‑level combination product quality alignment. The incumbent will mentor team members to provide individual development in addition to efficient and valuable service to project teams. Key Duties and Responsibilities Collaborate with internal and... | |
Pain Territory Account Manager, Tulsa, OKComm
Dec 3 $133,600 - $200,400 United States - Field Based Apply →Pain Territory Account Manager, Tulsa, OKApply →Comm
Dec 3 $133,600 - $200,400
United States - Field BasedThe Pain Territory Account Manager (PTAM) is responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor ofNaVl.8 in acute pain. The PTAM develops deep & strategic account relationships within hospital settings, executing strategic account plans. This role will report into a Regional Field Leader and is responsible for leading engagement with 15-20 institutions (hospitals & ambulatory surgery centers) as well as select physicians within the hospital setting or hospital networks. This role will work alongside Territory Business Managers, a... | |
Associate Director, GMP Operational Quality (Hybrid)Quality
Dec 3 $152,200 - $228,300 Boston, MA Apply →Associate Director, GMP Operational Quality (Hybrid)Apply →Quality
Dec 3 $152,200 - $228,300
Boston, MAThe Associate Director is recognized as an expert in the principles and application of quality and regulatory compliance. The individual adapts to new and multiple projects, effectively ensuring alignment with corporate goals and compliance with regulatory requirements. This role is responsible for oversight and coordination of GMP activities in support of Commercial Release and serves as primary QA contact on cross-functional teams. The Associate Director manages and develops personnel and support department and functional activities. KEY DUTIES AND RESPONSIBILITIES The responsibilities of this role may include, but are not limited to, the following Responsible for oversight of analytical activities... | |
Global Medical Director, PovetaciceptApply →Med Practice
Dec 3 $236,800 - $355,200
Boston, MAThe Global Medical Affairs Strategy Medical Director will provide medical leadership for the Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of IgA Nephropathy (IgAN), primary Membranous Nephropathy (pMN), and generalized Myasthenia Gravis (gMG) that has best-in-class and pipeline-in-a-product potential across a variety of autoimmune diseases. This role will be responsible for developing the medical strategy and medical plan under the direction of the Global Medical Affairs Lead/Executive Director, as well as executing against the medical plan encompassing the pove programs, with a focus on gMG. This role will collaborate closely with... | |
Vertex Summer Intern 2026, Clinical and Quantitative PharmacologyResearch
Dec 2 $0 - $0; $33 - $50 Boston, MA Apply →Vertex Summer Intern 2026, Clinical and Quantitative PharmacologyApply →Research
Dec 2 $0 - $0; $33 - $50
Boston, MAKickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab. Why Vertex? Real Projects You’ll work on assignments that... | |
Meeting & Events ManagerApply →Dec 2 $112,000 - $168,000
Boston, MAThe Meetings & Events Manager will be expected to monitor and provide guidance to Preferred Logistics Agencies (PLA) in addition to independently planning and executing a broad range of complex in-person and virtual internal and external meetings, including highly visible engagements for Senior Leadership. The role will advise stakeholders, assist in the development of meeting strategies and guide cross-functional planning teams to ensure meeting logistics and planned activities are aligned and support the overall meeting goals and objectives. The role will work collaboratively with the Global M&E Management Team to identify, build, and propose process efficiencies and best practices for... | |
Pain Territory Business Manager, Jupiter, FLComm
Dec 2 $140,000 - $160,000 United States - Field Based Apply →Pain Territory Business Manager, Jupiter, FLApply →Comm
Dec 2 $140,000 - $160,000
United States - Field BasedThe Pain Territory Business Manager (TBM) is responsible for establishing and maintaining relationships with Health Care Professionals (HCPs) to promote the safe and effective use of JOURNAVX, a novel selective inhibitor of NaV1.8 in acute pain. The TBM reports into a Regional Field Leader and serves as a field representative for JOURNAVX within the community setting. The TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as... | |
Senior Director, Global Develoment Financial Planning & AnalysisDec 2 $212,000 - $318,000 Boston, MA Apply →Senior Director, Global Develoment Financial Planning & AnalysisApply →Dec 2 $212,000 - $318,000
Boston, MAVertex is growing at a rapid pace with challenging and exciting opportunities for motivated professionals who are keen to contribute to the Vertex mission to invest in scientific innovation to create transformative medicines for people with serious diseases. Our robust and complex R&D pipeline requires a focus on efficiency and prioritization as we scale. The Vertex finance function is integral to achieving our company’s strategic goals, providing critical insights and analysis in support of decision-making across the organization. We are investing in our ability to provide data-driven insights by organizing and automating financial data and processes to enable our growing... | |