Vertex Job Trends

The Clinical Pharmacology Associate will analyze and report on clinical pharmacology studies. A professional with non-compartmental PK analysis experience working in the development organization. The Clinical Pharmacology Associate will be a key part of the Clinical Pharmacology function supporting clinical study execution teams. The Clinical Pharmacology Associate, will also be assisting Clinical Pharmacology and cross-functional clinical teams to ensure the successful execution of Clinical Pharmacology strategies. Key Duties and Responsibilities Review pharmacokinetics concentration data & conduct non-compartmental PK analysis Assist in summarizing PK data and generate TFLs to support Clin Pharm updates Quality control (QC) reviews Prepare scientific reports and...

The Global Medical Affairs Publications Science Director for the Kidney Diseases portfolio leads global strategy, development, and execution of the Publication Plans across IgA Nephropathy (IgAN), APOL1 Mediated Kidney Disease (AMKD), primary Membranous Nephropathy (pMN), and Autosomal Dominant Polycystic Kidney Disease (ADPKD), working closely with the Global Medical Lead (GML). This role may expand as additional kidney diseases are added to the Therapeutic Area. This role may additionally include some development of medical content/materials, e.g., slide decks, FAQs and external facing materials, and will require engagement with key thought leaders and external experts. The role requires collaboration with cross-functional business...

The Marketing Operations Process & Analytics Senior Manager is responsible for managing the coordination, design, and delivery of commercial excellence initiatives that enhance Marketing Operations. Activities will support internal stakeholder engagement and data-driven decision making for North America. This role will be responsible for overseeing process improvement activities associated with the CRC (Communications Review Committee) and ensuring the appropriate use of its corresponding system. Furthermore, this role will have varied responsibilities to support the commercial team including developing and supporting the implementation of new Marketing Operations processes. Key Duties and Responsibilities Contributes to the development of all the CRC processes...

Vertex currently operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Pain, and the first CRISPR-based, gene therapy for sickle cell disease and transfusion-dependent beta thalassemia. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Type 1 diabetes, APOL-1 Mediated Kidney Disease, IgA nephropathy, Duchenne Muscular Dystrophy, and Alpha-1 Antitrypsin Deficiency (AATD). The Regional Access and Reimbursement Associate Director will help ensure appropriate access and reimbursement of Vertex cellular...

The Revenue Accounting Manager will be responsible for overseeing the accounting for the order-to-cash process and the delivery of accurate and timely financial information relating to certain product revenues, gross to net accounts and accounts receivable to meet the operational needs and internal and external reporting requirements of the North America Region. The role will partner closely with members of Trade and Distribution, Market Access, Finance, Global Revenue Accounting, Government Pricing and Third-Party Partners. The Manager will also be responsible for identifying and driving process improvement initiatives including automation and data analytics as well as supporting new product launches. Key...

Vertex is seeking a talented strategic colleague to serve in a critical role supporting the D isease S trategy T eam Program Office in the Office of the CEO . The Strategy & Operations Director will partner closely with a Disease Area Executive (DAE) to drive special initiatives to support a particular DST . We are seeking a candidate that has a strong track record in strategic role s , along with cross functional collaboration and effective communication s kills to apply for this opportunity. Key Duties and Responsibilities Partners with DAE to lead strategic projects and high-profile initiatives Act...

General/ The Global Medical Affairs Science Associate Director has a leading role in Global Medical Affairs, working on global activities for the Povetacicept Programs. Povetacicept is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of both IgA Nephropathy (IgAN) and primary Membranous Nephropathy (pMN) that has best-in-class and pipeline-in-a-product potential. Key responsibilities include, but are not limited to, supporting Medical Plan development, supporting creation and deployment of medical content and materials such as slide decks, FAQs and external facing materials, and congress planning. The role requires collaboration with cross-functional business partners, including regional medical teams, health economics...

This Commercial Manufacturing and Supply Chain (CMSC) Senior Project Manager will be responsible for supporting the cross-functional project teams executing our CMC and manufacturing strategies within our Povetacicept (POVE) program. The position will work with the CMSC and CMC leads and interface directly with CDMOs and internal cross-functional teams. The position will track and report project scope/timeline/milestone status associated with technical transfer (analytical/process), regulatory strategies and commitments, product manufacturing, process validation, product testing, capacity planning, and external partner strategy. This is an exciting and visible role for a highly qualified and motivated individual. The successful candidate will be detail-driven and...

The Senior Director, Enterprise Third Party Risk Leader will lead an expanded third party risk management E2E process, include leading a Central Risk Management team and driving a holistic, effective and efficient third party risk management approach for the enterprise. This leader will shape and maintain an integrated and enterprise view of third party risk exposure across a holistic set of risk dimensions , collecting inputs from function and business leads and reporting to key stakeholders. The role will also maintain a comprehensive understanding of the company’s business strategies, organizational structures, resources and risks, policies and procedures and have responsibility...

Vertex Pharmaceuticals is seeking a Senior Manager to join the North America Health Economics & Outcomes Research (HEOR) team in a cross - portfolio role (commercial ly available products + pipeline) to drive and support HEOR strategy and related tactics in the disease areas of P ain, C ystic F ibrosis, H ematology, K idney D isease and T ype - 1 D iabetes. This person will work in a cross-functional team environment, interfacing with key internal groups including Market Access , Medical Affairs, Clinical Development, Regulatory Affairs, Health Policy and Alliance Management , and others, to execute on a...

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops, and feel valued by the Vertex community. Not only will co-ops...

The Process Chemistry Scientific Fellow will develop and apply novel solutions to solve complex problems. This role will demonstrate mastery of drug development processes and quality and regulatory requirements by identifying needs and developing solutions in neighboring areas. Key Duties and Responsibilities Acts as a resource in one or more technical areas providing in-depth technical advice and developing theoretical premise for issues within discipline May identify and manage CRO or external collaborations development efforts within appropriate regulations and SOPs Explores specific new science projects and business initiatives for the company to consider Generates and reviews technical documentation such as reports...

The Senior Medical Science Liaison (Sr MSL) (T1D/islet cell therapy) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources...

The Director, FP&A – CSO G&A Functions is a key member of Vertex's Financial Planning & Analysis organization. The role partners closely with members of the DTE, DSS and BD-EI teams to provide financial direction and strategic insights to enable delivery against short term and long-term goals, including identification of key value drivers and Business KPIs. The Director business partners to provide strategic decision support, influence decisions and identify opportunities for investment, manage budgets prudently and mitigate financial risks on a global basis. Also, leads a team of center of excellence to support the other G&A functions. Key Duties and...

The Senior Medical Science Liaison (Sr MSL) (T1D/islet cell therapy) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources...

The Senior Medical Science Liaison (Sr MSL) (T1D/islet cell therapy) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources...

Vertex is a transformative biotechnology company that creates new possibilities in medicine to cure diseases and improve people’s lives and it is seeking a solutions-oriented healthcare attorney to provide proactive strategic and tactical legal support to the business. The company currently has four drugs on the market that treat the underlying cause of cystic fibrosis. It has also developed a deep pipeline, investing billions of dollars into R&D over the past two decades. As Legal Senior Counsel, you will be a part of our dynamic and highly respected Legal and Compliance Department in a US, remote location. The Department is...

The Senior Medical Science Liaison (Sr MSL) (T1D/islet cell therapy) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources...

The Formulation Senior Research Scientist will work with other scientists dedicated to preclinical formulation – advancing drug candidates from exploratory development through first in human studies using lab based and computational tools to design and select dosage forms and manufacturing processes. This role designs and executes elaborate experiments for pharmaceutical sciences projects and demonstrates resourcefulness in running multiple activities concurrently, all related to achievement of goals/objectives. Key Duties and Responsibilities Develop dosage forms for preclinical and early clinical use – conduct preformulation activities to enable all nonclinical in vivo studies (pharmacology, pharmacokinetic, and safety) Develop stable and bioavailable formulations for...

The US Tax Reporting & State Tax Manager will partner with Associate Director, US Tax Reporting, US Direct Tax Compliance & Technology on US tax reporting. You will be responsible for preparation, review, and/or supervision of all N.A. indirect taxes and state direct taxes, including compliance and tax controversy. Key Duties and Responsibilities Prepare/review US accounting for income tax computations and adhere to internal controls under Sarbanes-Oxley. Includes maintenance of monthly and quarterly account analyses and reconciliations for tax-related accounts. Will coordinate these responsibilities with Associate Director, US Tax Reporting & US Direct Compliance & Technology. Directly supervise third party...

The Senior Statistical Programmer II provides technical guidance on clinical project teams. Work is performed on the design, development, and quality control process for SAS programs used to access, extract, transform, review, analyze, and submit clinical data for individual studies. In addition, the Senior Statistical Programmer II participates in departmental and cross functional technology development and process improvement initiatives. Key Duties and Responsibilities Codes complex SAS programs (including Macro language, SAS/STAT and SAS/GRAPH) for applications designed to analyze and report complex clinical trial data and for electronic review, exchange, transformation, and submission of data in CDlSC SDTM format; consistently meeting...

General/ The Director, CMC Inspection Management as part of the Vertex Quality Assurance Organization is responsible for the inspection management related to CMC activities of the internal manufacturing site for Cell & Gene. This role will be responsible for the development of an inspection program for site compliance and maturity, inspection preparation, consistent state of readiness and inspection management. The role is responsible for designing the program, identifying risks, driving mitigation of such risks and supporting cross-functional partners in ensuring execution. Additional responsibilities include support for external site inspection readiness. Vertex is an exciting, fast paced dynamic environment with a...

POSITION SUMMARY The Senior Manager, Product Protection and Supply Chain Security, will manage and support Vertex’s programs to keep our medicines safe and secure across our commercial portfolio and clinical pipeline. This role is required to direct efforts across the company to prevent, detect, and respond to threats of counterfeiting, theft, and diversion. This role will be critical in developing and implanting a strategy for supply chain risk evaluation and mitigation. This role will report to the Director of Product Protection and Supply Chain Security and work closely with Supply Chain, Quality, Security, Legal and other key stakeholders. KEY RESPONSIBILITIES...

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people living with serious diseases, with a focus on specialty markets. We invest in diseases where there is a significant unmet need and we can have a transformative impact for patients, not just an incremental benefit. We invest the majority of our resources in research and development (R&D) to discover new medicines, because we believe the true value in our industry is unleashed through scientific innovation. Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treat—and even cure—several of...

General/ Vertex

Vertex Pharmaceuticals uses cutting edge science and technologies to create transformative therapies for the treatment of the most serious diseases with unmet medical need . Our culture enables individual empowerment where “We Wins” “Fearless Pursuit of Excellence” and “Innovation” are more than just corporate values They are part of our everyday lives. Preclinical Safety Assessment is a global function responsible for the design and execution of preclinical strategies for the comprehensive safety assessment of Vertex therapies at all stages of research and development, beginning in the early drug discovery phases and continuing through the entire drug development value chain resulting...

As Vertex looks to scale, the Business Process Excellence Associate Director prepares us for the future of work. In support of our Digital Innovation journey, the incumbent will drive process automation leveraging different technologies, identify and eliminate waste, and bring efficiency to our ways of working. The Business Process Excellence Associate Director partners with cross-functional teams/leaders to drive high-visibility, high-value business improvement initiatives to achieve desired results. The incumbent combines knowledge of departmental processes and systems, with effective project management techniques to ensure that initiatives meet scope and deliverables within identified time and cost constraints. The incumbent partners with key...

The Territory Account Manager will be responsible for establishing and maintaining relationships with key institutional decision makers and affiliated Health Care Professionals (HCPs) to generate advocacy and drive sales growth for the US Pain Business Unit, which is currently in launch phase of an investigational novel selective inhibitor of NaV1.8 in acute pain. We are looking for candidates with a strong track record of delivering exceptional results with patient focus, developing deep & strategic account relationships, and executing strategic account plans. Consistently demonstrating behaviors that embody Vertex’s values and earn the trust of stakeholders, developing deep expertise in the science...

The Senior Biostatistician II will perform scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with guidance and mentoring on new and complex issues. The incumbent will complete assigned work in a resourceful manner and create alternative approaches to achieve desired results. The incumbent will develop a good knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset. Key Duties and Responsibilities Within assigned area, designs, develops and executes the technical/statistical infrastructure for the conduct and evaluation of clinical trials, observational studies, or real world data (RWD) investigations, including related areas/activities. Participates...