Illumina Job Trends

The Senior Reliability Engineer within the Strategic Operations team ensures that consumables manufacturing systems in San Diego, CA, are optimally operated and maintained throughout their lifecycle. They support equipment engineer teams through the provision of reliability expertise and services in a fast pace regulated environment. They will work in a dynamic team-oriented environment that supports multiple operations and technologies helping Illumina deliver its highly complex product pipeline. Responsibilities Work closely with NPI and Equipment Engineering teams to assess and prepare equipment transfer from development to sustaining. Lead and execute the provision of maintenance dossiers for new equipment containing Criticality Studies,...

Staff AI Enablement, Manufacturing Lead sits at the forefront of Illumina’s AI transformation—driving the adoption, scale, and real‑world impact of AI and intelligent automation across Instrument and Consumables Manufacturing within our life sciences business. In this highly visible role, you will help translate cutting‑edge AI innovation into everyday operational advantage, enabling teams to understand what’s possible, generate high‑value demand, and deliver prioritized solutions that matter. You will serve as a catalyst for change—championing training, enablement, and adoption so AI becomes seamlessly embedded in how work gets done. Blending strong business influence, operational expertise, and AI fluency with a solid technical...

Location San Diego, CA Travel 20–25% The Staff Events Manager is responsible for executing high-profile internal and executive events globally, ensuring seamless delivery of programs that support company priorities and leadership engagement. This role partners closely with senior stakeholders to translate event strategies into high-quality, flawlessly executed experiences. This individual owns the full event lifecycle—from planning through execution and post-event reporting—ensuring alignment with organizational goals, brand standards, and operational excellence. The role requires strong executional leadership, exceptional project management, and ability to deliver complex programs in fast-paced, high-visibility environments. Success in this role requires exceptional project management capabilities, discretion,...

Designs, implements and maintains quality master data to support processing materials into partially finished or finished products and transacting them in the ERP system. Responsible for planning, implementing, improving, and managing compliance of quality master data, material movement, acceptance, and control processes. Assesses and performs these processes in alignment with internal and external safety, quality and regulatory standards requirements for worldwide distribution. Performs analysis of reports and ERP/ production data to identify trends and recommend updates or changes to quality standards and procedures when necessary. May assure compliance to in-house and/or external specifications and standards (i.e. GLP, GMP, ISO, Six...

Overview Hundreds of millions of human genomes and exomes are expected to be sequenced over the next decade, driven by steady innovations in sequencing technologies pioneered by Illumina. The enormous quantities of genomic data being generated by Illumina in collaboration with our partners worldwide represents a major opportunity to develop novel data-driven and artificial intelligence methods to extract clinically actionable information from the genome, and apply it towards improving human health. Our Exceptional Multi-disciplinary Team Is Unlocking The Power Of The Genome Illumina is the worldwide leader in genome sequencing and deriving insights on the impact of the human genome...

The Senior Talent Acquisition Coordinator works closely with other members of the Talent Acquisition team to assist in logistics and administrative support, scheduling, coordinating and onboarding. The Senior Talent Acquisition Coordinator is responsible for contacting candidates, scheduling interviews, ensuring a positive candidate experience, managing new employee onboarding including Form I-9s and managing special projects as assigned. Tasks and Responsibilities Collaborates with recruiters, hiring managers, executive assistants and candidates to coordinate high volume phone, virtual, and onsite interviews Manages several stages of the recruitment life-cycle process which includes, monitoring and clearing background checks, closing candidate records within applicant tracking system (Workday...

Illumina is seeking an Associate Human Factors Engineer to join our growing team of experience designers and researchers as we build best-in-class customer experiences across all Illumina hardware and software products. You must be skilled with human factors and ergonomics research, applied cognitive research and human-machine integration design. Successful candidates should have a foundation in designing medical device experiences and be familiar with appropriate standards including IEC 62366-1 and -2, ANSI/AAMI HE75 and FDA guidance on Applying Human Factors and Usability Engineering to Medical Devices. Experience with international regulatory bodies including IVDD and EU IVDR 2017/746 is a plus. In...

Position Director, Corporate Development Location Hybrid Reports To Senior Vice President of Corporate Development & Strategic Planning (eventually to Vice President, M&A) This role serves as a strategic leader, leading high‑impact M&A, partnership, and investment initiatives across the deal lifecycle. The Director is accountable for translating enterprise priorities into actionable external opportunity agendas, shaping investment strategy through rigorous analysis, and delivering executive‑level recommendations that inform capital allocation and long‑term growth. The individual brings a combination of deep scientific and technical insight and strategic investment rigor to independently assess complex external opportunities, develop and defend investment theses, and integrate...

The General Manager, USCAN Central East will be the face of the Illumina organization, setting out the strategic direction of the Central East sub-region and ensuring alignment of the different Illumina functions. A strategic, empowered leader who can drive the success of our business to support our local markets with local resourcing to maximize market opportunities. This leader is responsible for all customers within the geography across all customer segments. This leader will be one of five General Managers driving Illumina’s business in the US and Canada. Key Relationships Reports to USCAN Head of Region Direct reports 6 District Sales...

We are seeking a Software Engineer to join the Primary Analysis Test Team. The engineer will work closely with primary analysis developers to understand product requirements, translate them into effective test infrastructure and test strategies. The role is accountable for ensuring the reliability, robustness, refinement, and release readiness of primary analysis software. Focus will be on designing, developing, and maintaining automated test framework which validate core primary analysis functionality, boosting confidence in software during development. It also involves supporting continuous integration pipelines, collaborating across teams, tracking defects found during test cycles, supporting release candidate verification. Responsibilities Design, implement, and maintain...

As sequencing technology advances into clinical, diagnostic, and AI-driven applications, the regulatory and quality requirements governing software have become as demanding as those governing physical devices. IEC 62304 compliance, SaMD classification, EU AI Act readiness, and cybersecurity within the QMS are front-line regulatory risks. The Sr Director, Software Quality will establish and lead Illumina's standalone Software Quality function, reporting directly to the VP of Global Quality. This leader will define the operating model, build the team, and own the end-to-end quality framework for all software products and software-driven medical devices across Illumina's global portfolio. The role requires deep technical expertise,...

Illumina is seeking an experienced Upstream Product Manager to drive strategy and market intelligence for our high-throughput next-generation sequencing (NGS) platform portfolio, with a focus on the NovaSeq X and adjacent whole genome sequencing (WGS) solutions. This is a high-visibility role that sits at the intersection of market insight, competitive intelligence, and long-range strategy — directly informing how Illumina shapes the future of sequencing. You will serve as the voice of the market internally, translating customer research, competitive signals, and technology trends into clear strategic direction for R&D, commercial, and executive stakeholders. Key Responsibilities Market Research & Customer Insights Design...

Illumina's instruments generate more sequencing data than any other platform on earth. The strategic data programs you will deliver as part of our BioInsight business sit at the intersection of that data generation and the world's most consequential genomics research national genome projects sequencing entire populations, biopharma programs linking genomic variation to therapeutic targets, and clinical research initiatives building the evidence base for precision medicine. This is a role where your technical work directly enables scientific discovery at population scale. You will not be writing slide decks about what could be built. You will be building it, operating it, and...

Drives development and implementation of corporate policy through strategic partnerships with government and industry groups, aligning with business objectives. Works on a team to foster relationships with key members of the federal government and industry groups to promote company interests in Washington, D.C. Prepares policy briefings, testimony for pending legislative actions, and provides thought leadership and recommendations in collaboration with the government affairs team. Works on a team to ensure appropriate company participation in government forums and industry group meetings. Responsible for engaging with policymakers, leaders of government and industry councils, and lobbyists to influence public policy, monitor government initiatives,...

NovaSeq X Series Core Consumables As Staff / Sr. Staff Product Manager for the NovaSeq X Series Core Consumables portfolio, you will drive the business performance, strategic direction, and sustained growth of one of Illumina’s most critical high-throughput sequencing revenue lines. This role operates as the business owner for the NovaSeq X core consumables portfolio, responsible for identifying and executing the highest-impact levers to increase customer adoption, expand utilization across the installed base, improve portfolio mix, and strengthen long-term platform competitiveness. You will translate customer behavior, application trends, competitive dynamics, and installed base economics into clear product, pricing, and commercial...

Summary The validation engineer 2 works as an integral part of the validation team supporting new product introduction, sustaining manufacturing, computerized system introduction / sustaining. Collaborate in a dynamic team-oriented environment and lead the effort for defining, implementing and maintaining validation for manufacturing processes and systems. Become highly proficient in use of Validation Life Cycle Management System. Key Responsibilities Develops and articulates robust strategies for validation of processes/systems and generate validation plans Develops validation protocols for and oversee execution of IQ, OQ, PQ and manufacturing processes, systems and equipment in collaboration with end users and process owners Writes reports summarizing...

Illumina is seeking a driven and dynamic candidate to join a successful and expanding Finance organization. This role will suit a positive and hands-on candidate, who will have direct exposure in understanding the Illumina USCAN business, including its challenges and strategies. This position will also offer an opportunity to influence decision-making across the organization. The ideal candidate will provide quality financial and commercial input to individual investment decisions, understand/challenge key revenue forecasting assumptions, and deliver financial analysis of performance, forecasts, key risks and sensitivities. This candidate will be viewed by USCAN regional leaders as a financial process and data/systems expert...

The Associate Director, Operational Excellence is a pivotal leader and true partner across every function at Illumina. In this role, you’ll collaborate directly with the leadership team to drive high‑impact transformations that fuel our company strategy, deploy our Operational Excellence business systems, and build strong, self‑sustaining capabilities across the organization. This is an opportunity to be at the center of Illumina’s innovation engine — shaping how we operate, elevating our performance, and influencing the way teams across the company work and grow. You’ll thrive here if you love solving complex challenges, navigating across diverse disciplines, and empowering, inspiring, and mentoring...

Location San Diego, CA Strong onsite presence required. This is not a remote role. We are seeking a strategic, results-driven Director, IT SAP Finance/Commercial to own the delivery, operations, and evolution of our SAP Finance and Commercial landscape (Finance plus Order-to-Cash/Commercial capabilities) within a complex global environment. In this senior leadership role, you will be accountable for end-to-end value realization across the S/4HANA transformation and ongoing product roadmap—balancing deep domain expertise with executive partnership, people leadership, vendor/portfolio management, and budget accountability. You will serve as a primary liaison between IT and Finance/Commercial leadership, ensuring our SAP ecosystem enables growth,...

Position Director, Strategic Finance Location San Diego, CA (Hybrid – 2–3 days onsite weekly) Will consider Northern CA / Foster City Reports To VP, Strategic & Bioinsight Finance The Director, Strategic Finance is a senior finance leader responsible for shaping and advancing Illumina’s enterprise growth agenda through financial leadership across mergers and acquisitions, strategic investments, partnerships, alliances, joint ventures, divestitures, licensing arrangements, and new venture formation. The role serves as a trusted advisor to senior Finance and Executive Leadership, bringing rigorous financial analysis, strategic insight, and sound judgment to complex decisions that have meaningful enterprise impact. This role...

Head of Pharma Development We are seeking a visionary and strategic Head of Pharma Development to lead our pharmaceutical partnerships, data commercialization efforts, and AI-driven initiatives. This role will be instrumental in shaping the future of our pharma collaborations, driving innovation through data and technology, and unlocking new value across the drug development lifecycle. The successful candidate will report directly to the SVP of BioInsight and serve as a critical bridge between internal teams and external pharma stakeholders. Key Responsibilities Strategic Leadership Define and execute the pharma development and data strategy aligned with organizational goals. Serve as the primary...